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WO1999035907A3 - Modele - Google Patents

Modele Download PDF

Info

Publication number
WO1999035907A3
WO1999035907A3 PCT/IB1999/000217 IB9900217W WO9935907A3 WO 1999035907 A3 WO1999035907 A3 WO 1999035907A3 IB 9900217 W IB9900217 W IB 9900217W WO 9935907 A3 WO9935907 A3 WO 9935907A3
Authority
WO
WIPO (PCT)
Prior art keywords
animal model
xenobiotic
pylori infection
animal
model
Prior art date
Application number
PCT/IB1999/000217
Other languages
English (en)
Other versions
WO1999035907A2 (fr
Inventor
Giudice Giuseppe Del
Rino Rappuoli
Original Assignee
Chiron Spa
Giudice Giuseppe Del
Rino Rappuoli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9801000.2A external-priority patent/GB9801000D0/en
Priority claimed from GBGB9809398.2A external-priority patent/GB9809398D0/en
Priority claimed from GBGB9820976.0A external-priority patent/GB9820976D0/en
Application filed by Chiron Spa, Giudice Giuseppe Del, Rino Rappuoli filed Critical Chiron Spa
Priority to NZ500160A priority Critical patent/NZ500160A/en
Priority to JP53695899A priority patent/JP2001523116A/ja
Priority to AU20709/99A priority patent/AU2070999A/en
Priority to CA002283401A priority patent/CA2283401A1/fr
Priority to EP99901086A priority patent/EP0967858A2/fr
Publication of WO1999035907A2 publication Critical patent/WO1999035907A2/fr
Publication of WO1999035907A3 publication Critical patent/WO1999035907A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un modèle animal qui peut être infecté expérimentalement par Helicobacter pylori et qui présente les symptômes aigus d'une infection à Helicobacter pylori. On prépare ledit modèle en injectant à un animal, tel qu'un chien xénobiotique, une dose de bactéries antérieurement adaptées à la souris. L'invention concerne également l'utilisation d'un modèle animal pour le développement de vaccins, de médicaments chimiques et de méthodes diagnostiques.
PCT/IB1999/000217 1998-01-16 1999-01-15 Modele WO1999035907A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
NZ500160A NZ500160A (en) 1998-01-16 1999-01-15 Xenobiotic canine model of Helicobacter pylori infection
JP53695899A JP2001523116A (ja) 1998-01-16 1999-01-15 Ｈ．ｐｙｌｏｒｉ感染の生体異物動物モデル
AU20709/99A AU2070999A (en) 1998-01-16 1999-01-15 Xenobiotic animal model of H. Pylori infection
CA002283401A CA2283401A1 (fr) 1998-01-16 1999-01-15 Modele animal xenobiotique de l'infection h. pylori
EP99901086A EP0967858A2 (fr) 1998-01-16 1999-01-15 Modele

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9801000.2A GB9801000D0 (en) 1998-01-16 1998-01-16 Crystalline carbapenem intermediates and process for synthesis thereof
GB9801000.2 1998-01-16
GB9809398.2 1998-04-30
GBGB9809398.2A GB9809398D0 (en) 1998-04-30 1998-04-30 Immunization and treatment
GB9820976.0 1998-09-25
GBGB9820976.0A GB9820976D0 (en) 1998-09-25 1998-09-25 Immunization and treatment

Publications (2)

Publication Number Publication Date
WO1999035907A2 WO1999035907A2 (fr) 1999-07-22
WO1999035907A3 true WO1999035907A3 (fr) 1999-09-23

Family

ID=27269175

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1999/000217 WO1999035907A2 (fr) 1998-01-16 1999-01-15 Modele

Country Status (6)

Country Link
EP (1) EP0967858A2 (fr)
JP (1) JP2001523116A (fr)
AU (1) AU2070999A (fr)
CA (1) CA2283401A1 (fr)
NZ (1) NZ500160A (fr)
WO (1) WO1999035907A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001011953A1 (fr) * 1999-08-19 2001-02-22 Board Of Regents, The University Of Texas System Modele animal grande echelle d'aspergillose pulmonaire invasive chez un hote immunodeprime
CN116369278B (zh) * 2023-05-17 2024-09-20 上海溯源生物技术有限公司 一种幽门螺杆菌感染的动物模型构建方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009757A1 (fr) * 1994-09-28 1996-04-04 Biocine Spa Modele souris d'infection a helicobacter pylori
EP0757888A1 (fr) * 1994-12-13 1997-02-12 Yoshitomi Pharmaceutical Industries, Ltd. Gerbille de mongolie colonisee par helicobacter pylori, procede pour realiser cette colonisation, milieu pour la separation de helicobacter pylori et procede d'evaluation preliminaire de substances actives contre helicobacter pylori
WO1997011721A1 (fr) * 1995-09-25 1997-04-03 Astra Aktiebolag Procede pour identifier des composes therapeutiquement actifs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009757A1 (fr) * 1994-09-28 1996-04-04 Biocine Spa Modele souris d'infection a helicobacter pylori
EP0757888A1 (fr) * 1994-12-13 1997-02-12 Yoshitomi Pharmaceutical Industries, Ltd. Gerbille de mongolie colonisee par helicobacter pylori, procede pour realiser cette colonisation, milieu pour la separation de helicobacter pylori et procede d'evaluation preliminaire de substances actives contre helicobacter pylori
WO1997011721A1 (fr) * 1995-09-25 1997-04-03 Astra Aktiebolag Procede pour identifier des composes therapeutiquement actifs

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KRAKOWKA S ET AL: "Establishment of Campylobacter pylori infection in the neonatal gnotobiotic piglet", INFECTION AND IMMUNITY, vol. 55, no. 11, 1987, pages 2789 - 2796, XP002107381 *
LEE A: "Animal models for host-pathogen interaction studies", BR MED BULL, vol. 54, no. 1, 1998, pages 163 - 173, XP002107384 *
MARCHETTI M ET AL: "Development of a mouse model of Helicobacter pylori infection that mimics human disease", SCIENCE, vol. 267, 17 March 1995 (1995-03-17), pages 1655 - 1658, XP002107382 *
RADIN M ET AL: "Helicobacter pylori gastric infection in gnotobiotic beagle dogs", INFECTION AND IMMUNITY, vol. 58, no. 8, August 1990 (1990-08-01), pages 2606 - 2612, XP002107383 *
ROSSI G ET AL: "A conventional beagle dog model for acute and chronic infection with helicobacter pylori", INFECTION AND IMMUNITY, vol. 67, no. 6, June 1999 (1999-06-01), pages 3112 - 3120, XP002107385 *

Also Published As

Publication number Publication date
NZ500160A (en) 2002-03-01
EP0967858A2 (fr) 2000-01-05
WO1999035907A2 (fr) 1999-07-22
JP2001523116A (ja) 2001-11-20
AU2070999A (en) 1999-08-02
CA2283401A1 (fr) 1999-07-22

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