WO1999024070A3 - Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire - Google Patents
Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire Download PDFInfo
- Publication number
- WO1999024070A3 WO1999024070A3 PCT/EP1998/007020 EP9807020W WO9924070A3 WO 1999024070 A3 WO1999024070 A3 WO 1999024070A3 EP 9807020 W EP9807020 W EP 9807020W WO 9924070 A3 WO9924070 A3 WO 9924070A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hyaluronic acid
- biomedical
- ester derivatives
- viscoelastic properties
- healthcare field
- Prior art date
Links
- -1 Ester derivatives of hyaluronic acid Chemical class 0.000 title 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000010008 shearing Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Materials For Medical Uses (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU15598/99A AU1559899A (en) | 1997-11-06 | 1998-11-05 | Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITPD97A000253 | 1997-11-06 | ||
IT97PD000253A IT1296689B1 (it) | 1997-11-06 | 1997-11-06 | Derivati esterei dell'acido ialuronico aventi proprieta viscoelastiche e loro uso in campo biomedico-sanitario |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999024070A2 WO1999024070A2 (fr) | 1999-05-20 |
WO1999024070A3 true WO1999024070A3 (fr) | 1999-07-15 |
Family
ID=11391956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1998/007020 WO1999024070A2 (fr) | 1997-11-06 | 1998-11-05 | Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1559899A (fr) |
IT (1) | IT1296689B1 (fr) |
WO (1) | WO1999024070A2 (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6984623B2 (en) | 1993-12-07 | 2006-01-10 | Genetics, Institute Institute, LLC. | Tendon-inducing compositions |
US7091007B2 (en) | 1993-09-17 | 2006-08-15 | Genetics Institute, Llc | DNA molecules encoding BMP receptor proteins |
US7189392B1 (en) | 1999-10-15 | 2007-03-13 | Genetics Institute, Llc | Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins |
US7217691B2 (en) | 1986-07-01 | 2007-05-15 | Genetics Institute, Llc | Methods of treatment of periodontal disease |
US7226587B2 (en) | 2001-06-01 | 2007-06-05 | Wyeth | Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins |
US7323445B2 (en) | 1999-02-01 | 2008-01-29 | Genetics Institute, Llc | Methods and compositions for healing and repair of articular cartilage |
US7413753B2 (en) | 2001-06-08 | 2008-08-19 | Wyeth | Calcium phosphate delivery vehicles for osteoinductive proteins |
US9144631B2 (en) | 2003-01-27 | 2015-09-29 | Benedicte Asius | Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1302534B1 (it) * | 1998-12-21 | 2000-09-05 | Fidia Advanced Biopolymers Srl | Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per |
FR2794763B1 (fr) * | 1999-06-08 | 2001-08-24 | Centre Nat Rech Scient | Nouveaux derives de l'acide hyaluronique, leur preparation et leur utilisation |
EP1481695A1 (fr) * | 1999-10-15 | 2004-12-01 | Genetics Institute, LLC | Formulations a base d'acide hyaluronique aux fins de l'administration de proteines osteogenes |
CA2407925C (fr) * | 2000-05-03 | 2008-12-16 | Dennis Von Heimburg | Biomateriaux composes de cellules preadipocytes concus pour reparer des tissus mous |
JP2004530452A (ja) * | 2000-11-06 | 2004-10-07 | アルコン,インコーポレイテッド | 外科手術において使用するための非吸引性遷移粘弾性物質 |
US7820194B2 (en) | 2001-12-21 | 2010-10-26 | Alcon, Inc. | Combinations of viscoelastics for use during surgery |
CN1665525A (zh) | 2002-05-17 | 2005-09-07 | 惠氏公司 | 用于递送骨生成蛋白质的可注入固体透明质酸载体 |
US20100098772A1 (en) * | 2008-10-21 | 2010-04-22 | Allergan, Inc. | Drug delivery systems and methods for treating neovascularization |
IT1395392B1 (it) * | 2009-08-27 | 2012-09-14 | Fidia Farmaceutici | Geli viscoelastici come nuovi filler |
CN104725529A (zh) * | 2013-12-19 | 2015-06-24 | 上海建华精细生物制品有限公司 | 一种透明质酸衍生物的合成方法 |
CZ307158B6 (cs) * | 2016-12-23 | 2018-02-07 | Contipro A.S. | Oftalmologický prostředek |
IT201900019762A1 (it) * | 2019-10-24 | 2021-04-24 | Fidia Farm Spa | Composizione farmaceutica per uso nel trattamento della cistite di varia eziologia |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0216453A2 (fr) * | 1985-07-08 | 1987-04-01 | FIDIA S.p.A. | Esters de l'acide hyaluronique et leurs sels. |
EP0341745A1 (fr) * | 1988-05-13 | 1989-11-15 | FIDIA S.p.A. | Polysaccharides carboxylés réticulés |
WO1996037519A1 (fr) * | 1995-05-22 | 1996-11-28 | Fidia Advanced Biopolymers S.R.L. | Hydrogel polysaccharide, son procede de preparation et son utilisation en medecine, en chirurgie, en cosmetique et pour la preparation de produits d'hygiene |
WO1997049412A1 (fr) * | 1996-06-21 | 1997-12-31 | Fidia S.P.A. | Acide hyaluronique autoreticule et compositions pharmaceutiques associees pour le traitement des arthropathies |
-
1997
- 1997-11-06 IT IT97PD000253A patent/IT1296689B1/it active IP Right Grant
-
1998
- 1998-11-05 WO PCT/EP1998/007020 patent/WO1999024070A2/fr active Application Filing
- 1998-11-05 AU AU15598/99A patent/AU1559899A/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0216453A2 (fr) * | 1985-07-08 | 1987-04-01 | FIDIA S.p.A. | Esters de l'acide hyaluronique et leurs sels. |
EP0341745A1 (fr) * | 1988-05-13 | 1989-11-15 | FIDIA S.p.A. | Polysaccharides carboxylés réticulés |
WO1996037519A1 (fr) * | 1995-05-22 | 1996-11-28 | Fidia Advanced Biopolymers S.R.L. | Hydrogel polysaccharide, son procede de preparation et son utilisation en medecine, en chirurgie, en cosmetique et pour la preparation de produits d'hygiene |
WO1997049412A1 (fr) * | 1996-06-21 | 1997-12-31 | Fidia S.P.A. | Acide hyaluronique autoreticule et compositions pharmaceutiques associees pour le traitement des arthropathies |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Section Ch Week 9739, Derwent World Patents Index; Class B04, AN 97-418785, XP002102269 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7217691B2 (en) | 1986-07-01 | 2007-05-15 | Genetics Institute, Llc | Methods of treatment of periodontal disease |
US7300772B2 (en) | 1986-07-01 | 2007-11-27 | Genetics Institute, Llc | BMP products |
US7091007B2 (en) | 1993-09-17 | 2006-08-15 | Genetics Institute, Llc | DNA molecules encoding BMP receptor proteins |
US6984623B2 (en) | 1993-12-07 | 2006-01-10 | Genetics, Institute Institute, LLC. | Tendon-inducing compositions |
US7365052B2 (en) | 1993-12-07 | 2008-04-29 | Genetics Institute, Llc. | Tendon-inducing methods |
US7323445B2 (en) | 1999-02-01 | 2008-01-29 | Genetics Institute, Llc | Methods and compositions for healing and repair of articular cartilage |
US7189392B1 (en) | 1999-10-15 | 2007-03-13 | Genetics Institute, Llc | Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins |
US7226587B2 (en) | 2001-06-01 | 2007-06-05 | Wyeth | Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins |
US7413753B2 (en) | 2001-06-08 | 2008-08-19 | Wyeth | Calcium phosphate delivery vehicles for osteoinductive proteins |
US9144631B2 (en) | 2003-01-27 | 2015-09-29 | Benedicte Asius | Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
ITPD970253A0 (it) | 1997-11-06 |
AU1559899A (en) | 1999-05-31 |
WO1999024070A2 (fr) | 1999-05-20 |
ITPD970253A1 (it) | 1999-05-06 |
IT1296689B1 (it) | 1999-07-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1999024070A3 (fr) | Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire | |
EP0265116A3 (fr) | Esters réticulés d'acide hyaluronique | |
YU13602A (sh) | Čvrste lipidne smeše | |
AU7442398A (en) | Glucosamine fatty acid compositions and their use | |
WO2000069449A3 (fr) | Compositions de milieu de culture cellulaire conditionne et techniques d'utilisation | |
DE69534669D1 (de) | Nukleinsaeure enthaltende zusammensetzungen, herstellung und verwendung | |
DE69635609D1 (de) | Nukleinsäure enthaltende zusammensetzung, herstellung und verwendung | |
WO1997042975A3 (fr) | Compositions a base de chitosane et procedes de diffusion d'acides nucleiques dans une cellule | |
BRPI0210011B8 (pt) | cateter com septo de arrasto reduzido. | |
CA2282183A1 (fr) | 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines hydroxy substitue | |
MY130670A (en) | 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines | |
DE60113121T2 (de) | Herstellung von vernetzter Hyaluronsäure und dessen Hydrogel, daraus hergestellte Produkte und deren Verwendung | |
BR9908578A (pt) | Composição cosmética | |
WO1991005754A3 (fr) | Derives des alcools gras a longue chaine, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant | |
DE69031732D1 (de) | Verfahren zur herstellung von glykosid-estern und zusammensetzungen daraus | |
WO2001040240A3 (fr) | Dérivés de monosaccharides et de disaccharides | |
EP1193257A3 (fr) | Composés pour la transduction de signaux à médiation par la céramide | |
WO2007066309A3 (fr) | Composition cosmetique comprenant un ester d’acide dimerdilinoleique et d’un ou plusieurs polyols et un polymere semi-cristallin | |
EP1219636A3 (fr) | Mutéines d'érythropoiétine (EPO) modifiées, produites par des systèmes d'expression microbiologiques in vitro ou in vivo | |
AU3025795A (en) | Compositions which are suitable for employment as antidotes to blood anticoagulants, and their use | |
WO2000030667A3 (fr) | Compositions et methodes d'utilisation de lactadherine ou de ses variants | |
WO2003008457A3 (fr) | Esters polysaccharidiques d'acide retinoique | |
DE69635670D1 (de) | Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung | |
WO2005107828A3 (fr) | Articles médicaux inserables ou implantables ayant des surfaces biocompatibles modifiees covalentes | |
AU2703297A (en) | New derivatives of pregnane with no substituent in position 17-alpha, their use as medicaments, their preparation process, the intermediates of this process and the compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
NENP | Non-entry into the national phase |
Ref country code: KR |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: CA |