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WO1999024070A3 - Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field - Google Patents

Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field Download PDF

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Publication number
WO1999024070A3
WO1999024070A3 PCT/EP1998/007020 EP9807020W WO9924070A3 WO 1999024070 A3 WO1999024070 A3 WO 1999024070A3 EP 9807020 W EP9807020 W EP 9807020W WO 9924070 A3 WO9924070 A3 WO 9924070A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronic acid
biomedical
ester derivatives
viscoelastic properties
healthcare field
Prior art date
Application number
PCT/EP1998/007020
Other languages
French (fr)
Other versions
WO1999024070A2 (en
Inventor
Davide Renier
Alessandra Pavesio
Lanfranco Callegaro
Original Assignee
Fidia Advanced Biopolymers Srl
Davide Renier
Alessandra Pavesio
Lanfranco Callegaro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl, Davide Renier, Alessandra Pavesio, Lanfranco Callegaro filed Critical Fidia Advanced Biopolymers Srl
Priority to AU15598/99A priority Critical patent/AU1559899A/en
Publication of WO1999024070A2 publication Critical patent/WO1999024070A2/en
Publication of WO1999024070A3 publication Critical patent/WO1999024070A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Viscoelastic compositions are described comprised of esters of hyaluronic acid which are uniquely advantageous because their viscoelastic characteristics may vary according to shearing stress and temperature.
PCT/EP1998/007020 1997-11-06 1998-11-05 Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field WO1999024070A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU15598/99A AU1559899A (en) 1997-11-06 1998-11-05 Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITPD97A000253 1997-11-06
IT97PD000253A IT1296689B1 (en) 1997-11-06 1997-11-06 ESTERE DERIVATIVES OF HYALURONIC ACID HAVING VISCOELASTIC PROPERTIES AND THEIR USE IN THE BIOMEDICAL-HEALTH FIELD

Publications (2)

Publication Number Publication Date
WO1999024070A2 WO1999024070A2 (en) 1999-05-20
WO1999024070A3 true WO1999024070A3 (en) 1999-07-15

Family

ID=11391956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/007020 WO1999024070A2 (en) 1997-11-06 1998-11-05 Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field

Country Status (3)

Country Link
AU (1) AU1559899A (en)
IT (1) IT1296689B1 (en)
WO (1) WO1999024070A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1302534B1 (en) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl INJECTABLE, BIOCOMPATIBLE AND BIODEGRADABLE COMPOSITIONS INCLUDING AT LEAST A DERIVATIVE OF HYALURONIC ACID, CHONDROGENIC CELLS, FOR
FR2794763B1 (en) * 1999-06-08 2001-08-24 Centre Nat Rech Scient NOVEL HYALURONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE
EP1481695A1 (en) * 1999-10-15 2004-12-01 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
CA2407925C (en) * 2000-05-03 2008-12-16 Dennis Von Heimburg Biomaterials comprised of preadipocyte cells for soft tissue repair
JP2004530452A (en) * 2000-11-06 2004-10-07 アルコン，インコーポレイテッド Non-attractable transition viscoelastic materials for use in surgery
US7820194B2 (en) 2001-12-21 2010-10-26 Alcon, Inc. Combinations of viscoelastics for use during surgery
CN1665525A (en) 2002-05-17 2005-09-07 惠氏公司 Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
US20100098772A1 (en) * 2008-10-21 2010-04-22 Allergan, Inc. Drug delivery systems and methods for treating neovascularization
IT1395392B1 (en) * 2009-08-27 2012-09-14 Fidia Farmaceutici VISCOELASTIC FROSTS LIKE NEW FILLERS
CN104725529A (en) * 2013-12-19 2015-06-24 上海建华精细生物制品有限公司 Hyaluronic acid derivative synthesis method
CZ307158B6 (en) * 2016-12-23 2018-02-07 Contipro A.S. An ophthalmic preparation
IT201900019762A1 (en) * 2019-10-24 2021-04-24 Fidia Farm Spa Pharmaceutical composition for use in the treatment of cystitis of various etiology

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216453A2 (en) * 1985-07-08 1987-04-01 FIDIA S.p.A. Esters of hyaluronic acid and their salts.
EP0341745A1 (en) * 1988-05-13 1989-11-15 FIDIA S.p.A. Crosslinked carboxy polysaccharides
WO1996037519A1 (en) * 1995-05-22 1996-11-28 Fidia Advanced Biopolymers S.R.L. A polysaccharide hydrogel material, a process for its preparation and its use in medicine, surgery, cosmetics and for the preparation of health care products
WO1997049412A1 (en) * 1996-06-21 1997-12-31 Fidia S.P.A. Autocross-linked hyaluronic acid and related pharmaceutical compositions for the treatment of arthropathies

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216453A2 (en) * 1985-07-08 1987-04-01 FIDIA S.p.A. Esters of hyaluronic acid and their salts.
EP0341745A1 (en) * 1988-05-13 1989-11-15 FIDIA S.p.A. Crosslinked carboxy polysaccharides
WO1996037519A1 (en) * 1995-05-22 1996-11-28 Fidia Advanced Biopolymers S.R.L. A polysaccharide hydrogel material, a process for its preparation and its use in medicine, surgery, cosmetics and for the preparation of health care products
WO1997049412A1 (en) * 1996-06-21 1997-12-31 Fidia S.P.A. Autocross-linked hyaluronic acid and related pharmaceutical compositions for the treatment of arthropathies

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 9739, Derwent World Patents Index; Class B04, AN 97-418785, XP002102269 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7300772B2 (en) 1986-07-01 2007-11-27 Genetics Institute, Llc BMP products
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7365052B2 (en) 1993-12-07 2008-04-29 Genetics Institute, Llc. Tendon-inducing methods
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Also Published As

Publication number Publication date
ITPD970253A0 (en) 1997-11-06
AU1559899A (en) 1999-05-31
WO1999024070A2 (en) 1999-05-20
ITPD970253A1 (en) 1999-05-06
IT1296689B1 (en) 1999-07-14

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