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WO1999009177A3 - Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen - Google Patents

Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen Download PDF

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Publication number
WO1999009177A3
WO1999009177A3 PCT/DE1998/002379 DE9802379W WO9909177A3 WO 1999009177 A3 WO1999009177 A3 WO 1999009177A3 DE 9802379 W DE9802379 W DE 9802379W WO 9909177 A3 WO9909177 A3 WO 9909177A3
Authority
WO
WIPO (PCT)
Prior art keywords
virus
papilloma virus
therapy
agents
detection
Prior art date
Application number
PCT/DE1998/002379
Other languages
English (en)
French (fr)
Other versions
WO1999009177B1 (de
WO1999009177A2 (de
Inventor
Zur Hausen Ethel-M De Villiers
Hausen Harald Zur
Original Assignee
Deutsches Krebsforsch
Villiers Zur Hausen Ethel Mich
Hausen Harald Zur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch, Villiers Zur Hausen Ethel Mich, Hausen Harald Zur filed Critical Deutsches Krebsforsch
Priority to JP2000509841A priority Critical patent/JP2001514895A/ja
Priority to EP98949901A priority patent/EP1003877A2/de
Priority to US09/485,973 priority patent/US6488935B1/en
Publication of WO1999009177A2 publication Critical patent/WO1999009177A2/de
Publication of WO1999009177A3 publication Critical patent/WO1999009177A3/de
Publication of WO1999009177B1 publication Critical patent/WO1999009177B1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Die Erfindung betrifft eine DNA, die für ein Peptid eines Papillomvirus-Hauptcapsid-Proteins bzw. ein Papillomvirus-Genom codiert. Des weiteren betrifft die Erfindung durch das Papillomvirus-Genom codierte Proteine und gegen sie gerichtete Antikörper sowie deren Verwendung in Diagnose, Therapie und Vakzinierung.
PCT/DE1998/002379 1997-08-13 1998-08-12 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen WO1999009177A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2000509841A JP2001514895A (ja) 1997-08-13 1998-08-12 パピローマウイルス、該ウイルスの検出用試薬、および該ウイルスにより引き起こされる疾患の治療用試薬
EP98949901A EP1003877A2 (de) 1997-08-13 1998-08-12 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
US09/485,973 US6488935B1 (en) 1997-08-13 1998-08-12 Papilloma viruses, products for the detection thereof as well as for treating diseases caused by them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19735118.2 1997-08-13
DE19735118A DE19735118C1 (de) 1997-08-13 1997-08-13 Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen

Publications (3)

Publication Number Publication Date
WO1999009177A2 WO1999009177A2 (de) 1999-02-25
WO1999009177A3 true WO1999009177A3 (de) 1999-08-12
WO1999009177B1 WO1999009177B1 (de) 1999-09-16

Family

ID=7838878

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1998/002379 WO1999009177A2 (de) 1997-08-13 1998-08-12 Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen

Country Status (5)

Country Link
US (1) US6488935B1 (de)
EP (1) EP1003877A2 (de)
JP (1) JP2001514895A (de)
DE (1) DE19735118C1 (de)
WO (1) WO1999009177A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19735118C1 (de) * 1997-08-13 1998-08-13 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
DE19840263C1 (de) * 1998-09-03 2000-05-25 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
WO2009151697A2 (en) * 2008-03-14 2009-12-17 The Government Of United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and processes relating to human bocavirus
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー． 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235004A2 (de) * 1986-01-31 1987-09-02 Institut Pasteur Sonden für Papilloma-Virus und Verfahren zur Diagnose der Papilloma-Virusinfektionen
EP0451550A2 (de) * 1990-03-20 1991-10-16 BEHRINGWERKE Aktiengesellschaft Seroreaktive Epitope von den Proteinen 16 des menschlichen Papillomavirus (HPV)
WO1995030754A1 (de) * 1994-05-04 1995-11-16 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Für ein peptid eines papillomvirus-hauptcapsid-proteins codierende dna und dessen verwendungen
WO1997004099A2 (de) * 1995-07-19 1997-02-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
WO1998023752A2 (de) * 1996-11-26 1998-06-04 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
DE19735118C1 (de) * 1997-08-13 1998-08-13 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen
WO1998042847A2 (de) * 1997-03-25 1998-10-01 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomvirus-hauptcapsid-proteins und deren verwendung in diagnose, therapie und vakzinierung

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235004A2 (de) * 1986-01-31 1987-09-02 Institut Pasteur Sonden für Papilloma-Virus und Verfahren zur Diagnose der Papilloma-Virusinfektionen
EP0451550A2 (de) * 1990-03-20 1991-10-16 BEHRINGWERKE Aktiengesellschaft Seroreaktive Epitope von den Proteinen 16 des menschlichen Papillomavirus (HPV)
WO1995030754A1 (de) * 1994-05-04 1995-11-16 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Für ein peptid eines papillomvirus-hauptcapsid-proteins codierende dna und dessen verwendungen
WO1997004099A2 (de) * 1995-07-19 1997-02-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
WO1998023752A2 (de) * 1996-11-26 1998-06-04 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomviren, mittel zu deren nachweis sowie zur therapie von durch sie verursachten erkrankungen
WO1998042847A2 (de) * 1997-03-25 1998-10-01 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Papillomvirus-hauptcapsid-proteins und deren verwendung in diagnose, therapie und vakzinierung
DE19735118C1 (de) * 1997-08-13 1998-08-13 Deutsches Krebsforsch Papillomviren, Mittel zu deren Nachweis sowie zur Therapie von durch sie verursachten Erkrankungen

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
DELIUS H ET AL: "PRIMER-DIRECTED SEQUENCING OF HUMAN PAPILLOMAVIRUS TYPES", CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, vol. 186, 1994, pages 13 - 31, XP000602940 *
E.M. DE VILLIERS ET AL.: "An interlaboratory study to determine the presence of human papillomavirus DNA in esophageal carcinoma from China", EMBL SEQUENCE DATABASE, 11 August 1998 (1998-08-11), Heidelberg, FRG, XP002105381 *
G. ASTORI ET AL.: "Human papillomaviruses are commonly found in normal skin of imunocompetent hosts", J. INVEST. DERMATOLOGY, vol. 110, no. 5, May 1998 (1998-05-01), Blackwell Sciences Inc., Oxford, UK, pages 752 - 755, XP002105382 *
G. ASTORI ET AL.: "The papilomaviruses found in benign and malignant cutaneous lesions are present in normal skin", EMBL SEQUENCE DATABASE, 11 August 1998 (1998-08-11), Heidelberg, FRG, XP002094683 *
J. CLIN. MICROBIOL., vol. 33, no. 3, March 1995 (1995-03-01), ASM, WASHINGTON,DC,US, pages 690 - 695, XP002083613 *
J. INVEST. DERMATOLOGY, vol. 108, no. 1, January 1997 (1997-01-01), Blackwell Sciences Inc., Oxford, UK, pages 53 - 56 *
KIRNBAUER R ET AL: "EFFICIENT SELF-ASSEMBLY OF HUMAN PAPILLOMAVIRUS TYPE 16 L1 AND L1-L2 INTO VIRUS-LIKE PARTICLES", JOURNAL OF VIROLOGY, vol. 67, no. 12, December 1993 (1993-12-01), pages 6929 - 6936, XP000613170 *
R. HOPFL ET AL.: "Human papillomavirus DNA in non-melanoma skin cancers of a renal transplant recipient: detection of a new sequence related to epidermodysplasia verruciformis associated types", EMBL SEQUENCE DATABASE, 13 February 1997 (1997-02-13), Heidelberg, FRG, XP002105380 *
R.J. BERKHOUT ET AL.: "Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients", EMBL SEQUENCE DATABASE, 10 July 1995 (1995-07-10), Heidelberg, FRG, XP002105379 *
S.-Y. CHAN ET AL.: "Phylogenetic analysis of 48 papillomavirus types and 28 subtypes and variants: a showcase of the molecular evolution of DNA viruses", J. VIROLOGY, vol. 66, no. 10, October 1992 (1992-10-01), AM.SOC.MICROBIOL.,WASHINGTON,US, pages 5714 - 5725, XP002094682 *
SHAMANIN V ET AL: "DEVELOPMENT OF A BROAD SPECTRUM PCR ASSAY FOR PAPILLOMAVIRUSES AND ITS APPLICATION IN SCREENING LUNG CANCER BIOPSIES", JOURNAL OF GENERAL VIROLOGY, vol. 75, no. 5, May 1994 (1994-05-01), pages 1149 - 1156, XP000616268 *
V. SHAMANIN ET AL.: "Human papillomavirus infection in nonmelanoma skin cancers from renal transplant recipients and nonimmunosuppressed patients", J. NATL CANCER INST., vol. 88, no. 12, 19 June 1996 (1996-06-19), Bethesda, MD, US, pages 802 - 811, XP000616318 *
V. SHAMANIN ET AL.: "Specific types of human papillomavirus found in benign proliferations and carcinomas of the skin in immunosuppressed patients", CANCER RESEARCH, vol. 54, no. 17, 1 September 1994 (1994-09-01), AACR, BALTIMORE, US, pages 4610 - 4613, XP002094681 *
W.E. PIERCALL ET AL.: "Presence of human papilloma virus type 16 DNA sequences in human nonmelanoma skin cancers", J. INVEST. DERMATOLOGY, vol. 97, no. 5, November 1991 (1991-11-01), elsevier, new york, US, pages 880 - 884, XP002094680 *

Also Published As

Publication number Publication date
DE19735118C1 (de) 1998-08-13
WO1999009177B1 (de) 1999-09-16
WO1999009177A2 (de) 1999-02-25
JP2001514895A (ja) 2001-09-18
EP1003877A2 (de) 2000-05-31
US6488935B1 (en) 2002-12-03

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