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WO1999006598A3 - Determination d'alleles communs fonctionnels dans une population et applications de ceux-ci - Google Patents

Determination d'alleles communs fonctionnels dans une population et applications de ceux-ci Download PDF

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Publication number
WO1999006598A3
WO1999006598A3 PCT/US1998/016574 US9816574W WO9906598A3 WO 1999006598 A3 WO1999006598 A3 WO 1999006598A3 US 9816574 W US9816574 W US 9816574W WO 9906598 A3 WO9906598 A3 WO 9906598A3
Authority
WO
WIPO (PCT)
Prior art keywords
population
common functional
uses therefor
alleles
determining common
Prior art date
Application number
PCT/US1998/016574
Other languages
English (en)
Other versions
WO1999006598A2 (fr
Inventor
Patricia D Murphy
Original Assignee
Oncormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncormed Inc filed Critical Oncormed Inc
Priority to AU87768/98A priority Critical patent/AU8776898A/en
Publication of WO1999006598A2 publication Critical patent/WO1999006598A2/fr
Publication of WO1999006598A3 publication Critical patent/WO1999006598A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention a trait des méthodes d'identification de profils d'allèles d'un gène donné. Dans ces profils d'allèle fonctionnel figurent les allèles se présentant habituellement dans une population ainsi que les fréquences relatives de la survenue des allèles d'un gène donné. Ces profils d'allèle fonctionnel sont utiles en matière de traitement et de diagnostic de maladies, pour des applications en génétique et en pharmacogénétique ainsi que pour l'évaluation du degré auquel le gène ou les gènes se trouvent sous pression sélective.
PCT/US1998/016574 1997-08-04 1998-08-04 Determination d'alleles communs fonctionnels dans une population et applications de ceux-ci WO1999006598A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU87768/98A AU8776898A (en) 1997-08-04 1998-08-04 Determining common functional alleles in a population and uses therefor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US90577297A 1997-08-04 1997-08-04
US08/905,772 1997-08-04
US8447198A 1998-05-22 1998-05-22
US09/084,471 1998-05-22

Publications (2)

Publication Number Publication Date
WO1999006598A2 WO1999006598A2 (fr) 1999-02-11
WO1999006598A3 true WO1999006598A3 (fr) 1999-04-29

Family

ID=26771013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/016574 WO1999006598A2 (fr) 1997-08-04 1998-08-04 Determination d'alleles communs fonctionnels dans une population et applications de ceux-ci

Country Status (2)

Country Link
AU (1) AU8776898A (fr)
WO (1) WO1999006598A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9206478B2 (en) 2002-12-31 2015-12-08 Branhaven LLC Methods and systems for inferring bovine traits

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075163A2 (fr) * 2000-04-04 2001-10-11 Polygenyx, Inc. Procede d'haplotypage a haut debit
US6844154B2 (en) 2000-04-04 2005-01-18 Polygenyx, Inc. High throughput methods for haplotyping
ITMI20030434A1 (it) 2003-03-07 2004-09-08 Istituto Oncologico Romagnolo Coope Rativa Sociale Metodo per l'individuazione di tumori del colon-retto.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654155A (en) * 1996-02-12 1997-08-05 Oncormed, Inc. Consensus sequence of the human BRCA1 gene
WO1998005677A1 (fr) * 1996-08-05 1998-02-12 Oncormed, Inc. Mutation du gene de susceptibilite du cancer du sein et de l'ovaire
WO1998044157A2 (fr) * 1997-03-28 1998-10-08 Oncormed, Inc. Procedes d'identifications des variations de sequences polynucleotidiques

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654155A (en) * 1996-02-12 1997-08-05 Oncormed, Inc. Consensus sequence of the human BRCA1 gene
WO1998005677A1 (fr) * 1996-08-05 1998-02-12 Oncormed, Inc. Mutation du gene de susceptibilite du cancer du sein et de l'ovaire
WO1998044157A2 (fr) * 1997-03-28 1998-10-08 Oncormed, Inc. Procedes d'identifications des variations de sequences polynucleotidiques

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
AL MOUDALLAL Z ET AL.: "Monoclonal antibodies as probes of the antigenic structure of tobacco mosaic virus", THE EMBO JOURNAL, vol. 1, no. 8, 1982, pages 1005 - 1010, XP002095330 *
HACIA J G ET AL: "DETECTION OF HETEROZYGOUS MUTATIONS IN BRCA1 USING HIGH DENSITY OLIGONUCLEOTIDE ARRAYS AND TWO-COLOUR FLUORESCENCE ANALYSIS", NATURE GENETICS, vol. 14, no. 4, December 1996 (1996-12-01), pages 441 - 447, XP000615885 *
MADSEN H O ET AL: "A NEW FREQUENT ALLELE IS THE MISSING LINK IN THE STRUCTURAL POLYMORPHISM OF THE HUMAN MANNAN-BINDING PROTEIN", IMMUNOGENETICS, vol. 40, no. 1, 1994, pages 37 - 44, XP000609909 *
MATTILA P S ET AL.: "Extensive allele sequence variation in the J region of the human immunoglobin heavy chain gene locus", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 25, 1995, pages 2578 - 2582, XP002095329 *
MERAJVER ET AL: "Risk assessment and presymptomatic molecular diagnosis in hereditary breast cancer", CLINICS IN LABORATORY MEDICINE, vol. 1, no. 16, March 1996 (1996-03-01), pages 139 139, XP002079197 *
MORRISON N ET AL: "Frequent alleles of the human vitamin D receptor gene are functionally distinct", JOURNAL OF CELLULAR BIOCHEMISTRY. SUPPLEMENT, no. SUPPL. 16C, 21 February 1992 (1992-02-21), pages 20, XP002080808 *
WAINSCOAT J S ET AL.: "Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms", NATURE, vol. 319, 1986, pages 491 - 493, XP002095332 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9206478B2 (en) 2002-12-31 2015-12-08 Branhaven LLC Methods and systems for inferring bovine traits

Also Published As

Publication number Publication date
WO1999006598A2 (fr) 1999-02-11
AU8776898A (en) 1999-02-22

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