WO1998008499A1 - Biocidal compositions - Google Patents
Biocidal compositions Download PDFInfo
- Publication number
- WO1998008499A1 WO1998008499A1 PCT/IB1997/001068 IB9701068W WO9808499A1 WO 1998008499 A1 WO1998008499 A1 WO 1998008499A1 IB 9701068 W IB9701068 W IB 9701068W WO 9808499 A1 WO9808499 A1 WO 9808499A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- benzoic acid
- derivative
- animal
- composition
- animals
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 36
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 6
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 78
- 239000005711 Benzoic acid Substances 0.000 claims abstract description 39
- 235000010233 benzoic acid Nutrition 0.000 claims abstract description 39
- 241001465754 Metazoa Species 0.000 claims abstract description 38
- 241000282887 Suidae Species 0.000 claims abstract description 18
- 150000001413 amino acids Chemical class 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims abstract description 6
- 239000003651 drinking water Substances 0.000 claims abstract description 3
- 235000020188 drinking water Nutrition 0.000 claims abstract description 3
- 235000005911 diet Nutrition 0.000 claims description 6
- 230000037213 diet Effects 0.000 claims description 6
- 235000001014 amino acid Nutrition 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 4
- 150000001558 benzoic acid derivatives Chemical class 0.000 claims description 4
- 239000003792 electrolyte Substances 0.000 claims description 4
- 235000019752 Wheat Middilings Nutrition 0.000 claims description 3
- -1 alkali metal benzoates Chemical class 0.000 claims description 3
- 239000003139 biocide Substances 0.000 claims description 3
- 235000012054 meals Nutrition 0.000 claims description 3
- 235000019737 Animal fat Nutrition 0.000 claims description 2
- 241000283690 Bos taurus Species 0.000 claims description 2
- 244000068988 Glycine max Species 0.000 claims description 2
- 235000010469 Glycine max Nutrition 0.000 claims description 2
- 235000019735 Meat-and-bone meal Nutrition 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- 241000209140 Triticum Species 0.000 claims description 2
- 235000021307 Triticum Nutrition 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 2
- 235000019270 ammonium chloride Nutrition 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 235000005822 corn Nutrition 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 235000013343 vitamin Nutrition 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims description 2
- 229940088594 vitamin Drugs 0.000 claims description 2
- 229930003231 vitamin Natural products 0.000 claims description 2
- KWIPUXXIFQQMKN-UHFFFAOYSA-N 2-azaniumyl-3-(4-cyanophenyl)propanoate Chemical compound OC(=O)C(N)CC1=CC=C(C#N)C=C1 KWIPUXXIFQQMKN-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 1
- 229940090948 ammonium benzoate Drugs 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 abstract description 5
- 235000019621 digestibility Nutrition 0.000 abstract description 5
- 239000002253 acid Substances 0.000 abstract description 4
- 239000003242 anti bacterial agent Substances 0.000 abstract description 3
- 230000007423 decrease Effects 0.000 abstract description 3
- 150000001559 benzoic acids Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 6
- 229910021529 ammonia Inorganic materials 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Substances [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 208000012868 Overgrowth Diseases 0.000 description 1
- 235000019772 Sunflower meal Nutrition 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- VWSRWGFGAAKTQG-UHFFFAOYSA-N ammonium benzoate Chemical class [NH4+].[O-]C(=O)C1=CC=CC=C1 VWSRWGFGAAKTQG-UHFFFAOYSA-N 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 125000005605 benzo group Chemical group 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000010815 organic waste Substances 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
Definitions
- This invention relates to the use of compositions comprising benzoic acid for use as a medicament for animals, especially pigs, at the same time promoting growth thereof and improving the digestibility of amino acids fed to such animals.
- animal feed compositions comprising benzoic acid or salts thereof can be used to minimise the emission of odoriferous ammonia from organic wastes, especially animal excrements and manure.
- benzoic acid can be used instead of relatively expensive antibiotics for such animals and furthermore, such acid/salts have the advantage of being able to promote growth, decrease feed conversion and improve digestibility of amino acids in animal feeds.
- the present invention is a composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid / ' // vivo for use as a medicament for animals Benzoic acid or a derivative thereof capable of giving rise to benzoic acid
- benzoic acid and derivatives thereof may be suitably administered to the animals as a component of the animal feed or in their drinking water.
- Specific examples of derivatives of benzoic acid which can give rise to benzoic acid /// vivo include salts of benzoic acid such as eg the alkali metal- alkaline earth metal- and ammonium benzoates.
- the amount of benzoic acid oi a derivative thereof administered to the animal is suitably such that ii is sufficient to prevent/cure any infection in the animal in its capacity as a biocide
- Such an amount is suitably in the range from 0.001 - 5% based on the total weight of each feed fed to the animal.
- This amount may. however, be higher if the function of benzoic acid or a derivative thereof is not only to act as a biocide but also to control the pH of the animal excreta fed on such a diet in order to suppress the emission of ammonia from the excreta.
- Such higher amounts are suitably limited to a maximum of about 10% based on the total animal feed composition.
- the benzo e acid/salt functions inter alia as an antibiotic, promotes growth, decreases feed conversion and improves digestibility of amino acids administered in animal feeds.
- benzoic acid or a derivative thereof may be used in combination with conventional ingredients present in an animal feed composition (diet) such as calcium carbonates, electrolytes such as eg ammonium chloride, proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal, amino acids, animal fat, vitamins and trace minerals.
- Diet animal feed composition
- electrolytes such as eg ammonium chloride
- proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal
- amino acids animal fat, vitamins and trace minerals.
- the ratio of the electrolyte to the benzoic acid or a derivative thereof is suitably in the range from 0.5 : 1 to 5 : 1 w/w, preferably from 1.5 : 1 to 3 : I w/w.
- Benzoic acid or a derivative thereof is particularly effective as a medicament for animals such as poultry, pigs or cattle, especially pigs.
- *-lt is a blend of Ca (25%) and a mixture of carboxylic acids (75%) - the acids and their amounts in the mixture being formic (30%). acetic (30%) propionic (30%) and citric (10%).
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
This invention relates to a composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid in vivo for use as a medicament for animals, wherein said acid/derivative functions as an antibiotic, promotes growth, decreases feed conversion and improves digestibility of amino acids administered in animal feeds. The benzoic acid or its derivative can be administered to the animal either in its feed composition or in its drinking water. It is particularly effective in pigs.
Description
B1OCIDAL COMPOSITIONS
This invention relates to the use of compositions comprising benzoic acid for use as a medicament for animals, especially pigs, at the same time promoting growth thereof and improving the digestibility of amino acids fed to such animals.
It is known from our own prior published EP-A-0683985 that animal feed compositions comprising benzoic acid or salts thereof can be used to minimise the emission of odoriferous ammonia from organic wastes, especially animal excrements and manure.
It has now been found that in addition to the above function, benzoic acid can be used instead of relatively expensive antibiotics for such animals and furthermore, such acid/salts have the advantage of being able to promote growth, decrease feed conversion and improve digestibility of amino acids in animal feeds.
Accordingly, the present invention is a composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid /'// vivo for use as a medicament for animals Benzoic acid or a derivative thereof capable of giving rise to benzoic acid
//•/ vivo may be administered to the animals as a component of a composition which is conventionally fed to animals. Thus, benzoic acid and derivatives thereof may be suitably administered to the animals as a component of the animal feed or in their drinking water. Specific examples of derivatives of benzoic acid which can give rise to benzoic acid /// vivo include salts of benzoic acid such as eg the alkali metal- alkaline earth metal- and ammonium benzoates.
The amount of benzoic acid oi a derivative thereof administered to the animal is suitably such that ii is sufficient to prevent/cure any infection in the animal in its capacity as a biocide Such an amount is suitably in the range from 0.001 - 5% based on the total weight of each feed fed to the animal. This amount may.
however, be higher if the function of benzoic acid or a derivative thereof is not only to act as a biocide but also to control the pH of the animal excreta fed on such a diet in order to suppress the emission of ammonia from the excreta. Such higher amounts are suitably limited to a maximum of about 10% based on the total animal feed composition. The benzo e acid/salt functions inter alia as an antibiotic, promotes growth, decreases feed conversion and improves digestibility of amino acids administered in animal feeds.
A typical formulation for an animal feed composition is shown in Table 1 below in which all the amounts shown in % by weight were fed to pigs:
TABLE 1
Thus, benzoic acid or a derivative thereof may be used in combination with conventional ingredients present in an animal feed composition (diet) such as calcium carbonates, electrolytes such as eg ammonium chloride, proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal, amino acids, animal fat, vitamins and trace minerals.
In such a composition, the ratio of the electrolyte to the benzoic acid or a derivative thereof is suitably in the range from 0.5 : 1 to 5 : 1 w/w, preferably from 1.5 : 1 to 3 : I w/w.
Benzoic acid or a derivative thereof is particularly effective as a medicament for animals such as poultry, pigs or cattle, especially pigs.
The present invention is further illustrated with reference to the following Examples: EXAMPLE 1:
The following feed compositions (shown in Table 2 below) in which all the amounts shown in % by weight were fed to pigs.
TABLE 2
The pH of the urine of the pigs fed on these diets for two days was monitored over various durations and found to be as follows (see Table 3 below):
TABLE 3
*First excretion by the pigs after the two day feeding stage.
From these results it is abundantly clear that the use of the additives of the present invention gives rise to excrements of highly acidic and stable pH values and consequently gives rise to little or no ammonia emissions. EXAMPLE 2:
In a further comparative test, a number of pigs were fed with a standard feed as shown below in Table 4 This was repeated in Example 2 except that 0.7% wt. of the wheat middlings in the standard feed was replaced with benzoic acid. The results are shown in Table 5 below:
TABLE 4
*0.7% wt of the wheat middlings in the standard fee replaced by benzoic acid.
The above results show that pigs fed with a diet comprising benzoic acid have a much lower feed conversion (calculated as a ratio of feed intake over growth per pig per day) than those eel on a diet tree of such benzoic acid. This signifies that the feed to the pigs is being used more efficiently. Example 3:
The effect of the experimental feed containing benzoic acid on the performance of the pigs was compared with the control feed which did not contain any benzoic acid. A pig room with six pens was used for this example during three periods. In three pens pigs were fed with the control feed, and in the other three pens pigs were fed with the experimental feed The feed compositions are shown in the Table 6 and the performance results are shown in Table 7 below. It, can be seen from Table 7 that the pigs fed on the experimental feed had a significant lower feed conversion ratio. This is probably due to the lower pH in the intestine which perhaps improves digestibility.
TABLE 6
*-lt is a blend of Ca (25%) and a mixture of carboxylic acids (75%) - the acids and their amounts in the mixture being formic (30%). acetic (30%) propionic (30%) and citric (10%).
Calculated Chemical Composition
# - Unii Energy value = X X MJ net available energy for pigs for production and maintenance
TABLE 7
Performance of Experimental Pigs
Claims
Claims
1 A composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid /// vivo for use as a medicament for animals
2 A composition according to Claim 1 wherein benzoic acid or a derivative thereof capable of giving rise to benzoic acid /// vivo is administered to the animals as a component of an animal feed composition.
3 A composition according to Claim I wherein benzoic acid and derivatives thereof are administered to the animals as a component of the drinking water fed to the animals 4 A composition according to any one of the preceding Claims wherein derivatives of benzoic acid which can give rise to benzoic acid /// vivo are salts of benzoic acid selected from the alkali metal benzoates, alkaline earth metal benzoates and ammonium benzoate
5 A composition according to any one of the preceding Claims wherein the amount of benzoic acid or a derivative thereof administered to the animal is such that it is sufficient to act as a biocide
6 A composition according to any one of the preceding Claims wherein the amount of benzoic acid or a derivative thereof is limited to a maximum of about 10% based on the total animal feed composition 7 A composition according to any one of the preceding Claims wherein the amount of benzoic acid or a derivative thereof administered to the animal is in the range from 0 001 - 5% based on the total weight of each feed fed to the animal. 8 A composition according to any one of the preceding Claims wherein the benzoic acid or a derivative thereof is administered to the animal in combination with one or more of the following ingredients present in an animal feed
composition (diet) calcium caibonates, electrolytes including inter alia ammonium chloride, pi tems including inl t alia soya bean meal, wheat, starch, sunflowei meal, corn, meat and bone meal, amino acids, animal fat, vitamins, and tiace minerals
9 A composition accoi ing to Claim 8 wheiem the ratio of the electrolyte to the benzoic acid oi a deπvalive theieof in the animal feed composition is in the range from 0 5 I to 5 1 w/w
10 A formulation foi an animal feed composition as shown in the Table below in which ail the amounts shown tn % by weight
1 1 A an animal feed composition compiismg benzoic acid or a derivative theieof whenevei admmistei ed as a medicament for animals selected from poultiy, pigs and cattle
I 12 A composition accoi ing to any one of the piecedmg Claims wherein benzoic acid is used in a pig teed loi mulation compi ismg the components shown in Tables 4 and 8 below
20
TABLE 4
TABLE 8
"0.7% wt of the wheat middlings in the standard fee replaced by benzoic acid.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9711977A BR9711977A (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
| AU40277/97A AU4027797A (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
| PL331763A PL191241B1 (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
| EP97937758A EP0921792A1 (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
| CA2265046A CA2265046C (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9618008.8A GB9618008D0 (en) | 1996-08-27 | 1996-08-27 | Biocidal compositions |
| GB9618008.8 | 1996-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1998008499A1 true WO1998008499A1 (en) | 1998-03-05 |
Family
ID=10799084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB1997/001068 WO1998008499A1 (en) | 1996-08-27 | 1997-08-19 | Biocidal compositions |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0921792A1 (en) |
| KR (1) | KR100505971B1 (en) |
| CN (1) | CN1236314A (en) |
| AU (1) | AU4027797A (en) |
| BR (1) | BR9711977A (en) |
| CA (1) | CA2265046C (en) |
| GB (1) | GB9618008D0 (en) |
| PL (1) | PL191241B1 (en) |
| WO (1) | WO1998008499A1 (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1016974C2 (en) * | 2000-12-22 | 2002-06-25 | Dsm Nv | Benzoic acid particles. |
| WO2007079970A1 (en) | 2006-01-13 | 2007-07-19 | Dsm Ip Assets B.V. | Novel use of a nutraceutical composition in animal feed |
| DE102006021392A1 (en) * | 2006-05-08 | 2007-11-15 | Ligrana Gmbh | Composition, useful in animal nutrition or for fattening animals, preferably for breeding and/or fattening pig, comprises benzoic acid, wetting agent and releasing agent |
| JP2009029789A (en) * | 2007-06-26 | 2009-02-12 | Marubeni Nisshin Feed Co Ltd | Composition for prevention and treatment of urinary tract infections in livestock |
| EP2042041A3 (en) * | 2007-06-29 | 2009-05-13 | DSMIP Assets B.V. | Use of benzoic acid and thymol, eugenol and piperine in animal feeding |
| DE102016203477A1 (en) | 2016-03-03 | 2017-09-07 | Addcon Europe Gmbh | Preparation and use of alkali metal diformates with medium-chain fatty acid derivatives |
| WO2020002595A1 (en) | 2018-06-29 | 2020-01-02 | Dsm Ip Assets B.V. | Fast release benzoic acid in feed |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104686814A (en) * | 2015-02-16 | 2015-06-10 | 广州英赛特生物技术有限公司 | Application of p-methyl benzoic acid or salt thereof as animal feed additive |
| DE102016101603B3 (en) | 2016-01-29 | 2017-05-11 | Hanon Systems | Fastening element and method for fastening fluid pipe ends |
| CN105661046B (en) * | 2016-02-23 | 2020-12-18 | 广州英赛特生物技术有限公司 | Application of calcium benzoate in preparation of animal feed additive |
| CN108617856A (en) * | 2018-03-14 | 2018-10-09 | 广州英赛特生物技术有限公司 | Application of the zinc benzoate in preparing animal feed additive |
| KR102703901B1 (en) * | 2023-07-26 | 2024-09-06 | 남이현 | Pig feed composition for immunity enhancement and weight gain |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1535233A (en) * | 1975-02-19 | 1978-12-13 | Plate Kofasil Gmbh | Method for preventing aerobic decomposition processes in fermentated fodder |
| GB2008381A (en) * | 1977-11-19 | 1979-06-06 | Basf Ag | Animal Feed supplements |
| GB2109217A (en) * | 1981-08-04 | 1983-06-02 | Nitrokemia Ipartelepek | Fodder and fodder additives promoting the weight increase of domestic animals and a process for the preparation thereof |
| WO1993016611A1 (en) * | 1992-02-27 | 1993-09-02 | Kemira Oy | Preservative compositions for a plant material |
| JPH06298641A (en) * | 1993-02-19 | 1994-10-25 | Takeda Chem Ind Ltd | Agent for preventing and treating urinary calculus of pet and method for treating the same disease |
| JPH07228533A (en) * | 1994-02-17 | 1995-08-29 | Jun Kimura | Drink agent for animal |
| EP0683985A1 (en) * | 1994-05-27 | 1995-11-29 | Verdugt B.V. | Control of ammonia emission and odour from animal excrements |
| WO1996024247A1 (en) * | 1995-02-06 | 1996-08-15 | Kemira Chemicals Oy | New preservative composition |
| US5603945A (en) * | 1993-02-19 | 1997-02-18 | Takeda Chemical Industries, Ltd. | Therapeutic/prophylactic agents and method of treating for urinary calculosis in pets |
-
1996
- 1996-08-27 GB GBGB9618008.8A patent/GB9618008D0/en active Pending
-
1997
- 1997-08-19 PL PL331763A patent/PL191241B1/en unknown
- 1997-08-19 AU AU40277/97A patent/AU4027797A/en not_active Abandoned
- 1997-08-19 EP EP97937758A patent/EP0921792A1/en not_active Ceased
- 1997-08-19 KR KR10-1999-7001506A patent/KR100505971B1/en not_active Expired - Lifetime
- 1997-08-19 WO PCT/IB1997/001068 patent/WO1998008499A1/en not_active Application Discontinuation
- 1997-08-19 CN CN97198985A patent/CN1236314A/en active Pending
- 1997-08-19 CA CA2265046A patent/CA2265046C/en not_active Expired - Lifetime
- 1997-08-19 BR BR9711977A patent/BR9711977A/en active Search and Examination
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1535233A (en) * | 1975-02-19 | 1978-12-13 | Plate Kofasil Gmbh | Method for preventing aerobic decomposition processes in fermentated fodder |
| GB2008381A (en) * | 1977-11-19 | 1979-06-06 | Basf Ag | Animal Feed supplements |
| GB2109217A (en) * | 1981-08-04 | 1983-06-02 | Nitrokemia Ipartelepek | Fodder and fodder additives promoting the weight increase of domestic animals and a process for the preparation thereof |
| WO1993016611A1 (en) * | 1992-02-27 | 1993-09-02 | Kemira Oy | Preservative compositions for a plant material |
| JPH06298641A (en) * | 1993-02-19 | 1994-10-25 | Takeda Chem Ind Ltd | Agent for preventing and treating urinary calculus of pet and method for treating the same disease |
| US5603945A (en) * | 1993-02-19 | 1997-02-18 | Takeda Chemical Industries, Ltd. | Therapeutic/prophylactic agents and method of treating for urinary calculosis in pets |
| JPH07228533A (en) * | 1994-02-17 | 1995-08-29 | Jun Kimura | Drink agent for animal |
| EP0683985A1 (en) * | 1994-05-27 | 1995-11-29 | Verdugt B.V. | Control of ammonia emission and odour from animal excrements |
| WO1996024247A1 (en) * | 1995-02-06 | 1996-08-15 | Kemira Chemicals Oy | New preservative composition |
| WO1996024248A1 (en) * | 1995-02-06 | 1996-08-15 | Kemira Chemicals Oy | Antimicrobic composition and its use |
Non-Patent Citations (2)
| Title |
|---|
| DATABASE WPI Section Ch Week 9502, Derwent World Patents Index; Class B05, AN 95-011742, XP002046599 * |
| DATABASE WPI Section Ch Week 9543, Derwent World Patents Index; Class B05, AN 95-332478, XP002046600 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1016974C2 (en) * | 2000-12-22 | 2002-06-25 | Dsm Nv | Benzoic acid particles. |
| WO2002051785A1 (en) * | 2000-12-22 | 2002-07-04 | Dsm N.V. | Benzoic acid particles |
| WO2007079970A1 (en) | 2006-01-13 | 2007-07-19 | Dsm Ip Assets B.V. | Novel use of a nutraceutical composition in animal feed |
| DE102006021392A1 (en) * | 2006-05-08 | 2007-11-15 | Ligrana Gmbh | Composition, useful in animal nutrition or for fattening animals, preferably for breeding and/or fattening pig, comprises benzoic acid, wetting agent and releasing agent |
| DE102006021392B4 (en) * | 2006-05-08 | 2013-06-27 | Ligrana Gmbh | composition |
| JP2009029789A (en) * | 2007-06-26 | 2009-02-12 | Marubeni Nisshin Feed Co Ltd | Composition for prevention and treatment of urinary tract infections in livestock |
| EP2042041A3 (en) * | 2007-06-29 | 2009-05-13 | DSMIP Assets B.V. | Use of benzoic acid and thymol, eugenol and piperine in animal feeding |
| RU2400101C2 (en) * | 2007-06-29 | 2010-09-27 | ДСМ АйПи АССЕТС Б.В. | Composition for animal fodder |
| EP2368440A1 (en) * | 2007-06-29 | 2011-09-28 | DSM IP Assets B.V. | Feed additive composition comprising an organic acid and and at least one adsorbed essential oil compound |
| JP2014057591A (en) * | 2007-06-29 | 2014-04-03 | Dsm Ip Assets Bv | Feed additive composition and use thereof |
| DE102016203477A1 (en) | 2016-03-03 | 2017-09-07 | Addcon Europe Gmbh | Preparation and use of alkali metal diformates with medium-chain fatty acid derivatives |
| WO2020002595A1 (en) | 2018-06-29 | 2020-01-02 | Dsm Ip Assets B.V. | Fast release benzoic acid in feed |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4027797A (en) | 1998-03-19 |
| CA2265046A1 (en) | 1998-03-05 |
| CA2265046C (en) | 2010-05-25 |
| PL191241B1 (en) | 2006-04-28 |
| KR100505971B1 (en) | 2005-08-05 |
| EP0921792A1 (en) | 1999-06-16 |
| GB9618008D0 (en) | 1996-10-09 |
| BR9711977A (en) | 1999-08-24 |
| KR20000035832A (en) | 2000-06-26 |
| PL331763A1 (en) | 1999-08-02 |
| CN1236314A (en) | 1999-11-24 |
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