+

WO1998001460A8 - Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein - Google Patents

Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein

Info

Publication number
WO1998001460A8
WO1998001460A8 PCT/US1997/011946 US9711946W WO9801460A8 WO 1998001460 A8 WO1998001460 A8 WO 1998001460A8 US 9711946 W US9711946 W US 9711946W WO 9801460 A8 WO9801460 A8 WO 9801460A8
Authority
WO
WIPO (PCT)
Prior art keywords
brca1
methods
compositions
diagnosis
treatment
Prior art date
Application number
PCT/US1997/011946
Other languages
English (en)
Other versions
WO1998001460A1 (fr
WO1998001460A9 (fr
Inventor
Wen-Hwa Lee
Yumay Chen
Chi-Fen Chen
Phang-Lang Chen
Andrew A Farmer
Diane C Jones
D Craig Allred
C Kent Osborne
Original Assignee
Univ Texas
Lee Wen Hwa
Yumay Chen
Chen Chi Fen
Chen Phang Lang
Andrew A Farmer
Diane C Jones
D Craig Allred
C Kent Osborne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Lee Wen Hwa, Yumay Chen, Chen Chi Fen, Chen Phang Lang, Andrew A Farmer, Diane C Jones, D Craig Allred, C Kent Osborne filed Critical Univ Texas
Priority to AU36550/97A priority Critical patent/AU736210B2/en
Priority to JP50534598A priority patent/JP2002513272A/ja
Priority to NZ333635A priority patent/NZ333635A/en
Priority to EP97933344A priority patent/EP0918788A4/fr
Publication of WO1998001460A1 publication Critical patent/WO1998001460A1/fr
Publication of WO1998001460A9 publication Critical patent/WO1998001460A9/fr
Publication of WO1998001460A8 publication Critical patent/WO1998001460A8/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des procédés et des compositions s'appliquant au diagnostic et au traitement du cancer du sein et autres cancers apparentés. L'invention concerne également des compositions et des procédés de détection du produit génique BRCA1 in vivo et in vitro, ainsi que des procédés de diagnostic de localisation aberrante de la protéine BRCA1 dans des cellules mettant en oeuvre des anticorps anti-BRCA1. L'invention concerne de plus des procédés d'identification des protéines associées à BRCA1 qui agissent dans la translocation correcte du produit génique BRCA1 vers le noyau cellulaire.
PCT/US1997/011946 1996-07-08 1997-07-08 Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein WO1998001460A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU36550/97A AU736210B2 (en) 1996-07-08 1997-07-08 Brca1 compositions and methods for the diagnosis and treatment of breast cancer
JP50534598A JP2002513272A (ja) 1996-07-08 1997-07-08 乳癌の診断および処置のためのｂｒｃａ１組成物および方法
NZ333635A NZ333635A (en) 1996-07-08 1997-07-08 BRCA1 associated proteins and peptides and the nucleotide encoding such proteins
EP97933344A EP0918788A4 (fr) 1996-07-08 1997-07-08 Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1586396P 1996-07-08 1996-07-08
US60/015,863 1996-07-08

Publications (3)

Publication Number Publication Date
WO1998001460A1 WO1998001460A1 (fr) 1998-01-15
WO1998001460A9 WO1998001460A9 (fr) 1998-04-23
WO1998001460A8 true WO1998001460A8 (fr) 2000-01-06

Family

ID=21774065

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/011946 WO1998001460A1 (fr) 1996-07-08 1997-07-08 Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein

Country Status (7)

Country Link
EP (1) EP0918788A4 (fr)
JP (1) JP2002513272A (fr)
KR (1) KR20000023600A (fr)
AU (1) AU736210B2 (fr)
CA (1) CA2259154A1 (fr)
NZ (1) NZ333635A (fr)
WO (1) WO1998001460A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0950189A4 (fr) 1996-08-02 2000-06-07 Wistar Inst Proteine bap-1 associee a la brca1 et ses utilisations
WO2001025255A2 (fr) * 1999-10-07 2001-04-12 Baylor College Of Medicine Nouvelle proteine a doigt de zinc
EP1399460A4 (fr) * 2001-04-27 2005-04-13 Sunnybrook & Women S College H Genes associes au cancer du sein et utilisations correspondantes
KR100468466B1 (ko) * 2001-08-25 2005-01-27 주식회사 랩 지노믹스 유방암 및 난소암 진단에 유용한 ｂｒｃａ１, ｂｒｃａ２유전자 돌연변이 및 이를 이용한 검색 방법
WO2003023404A1 (fr) * 2001-09-12 2003-03-20 The Walter And Eliza Hall Institute Of Medical Research Procede de diagnostic et de traitement et agents mis en oeuvre par ledit procede
CN111253483B (zh) * 2020-03-02 2021-07-30 江苏莱森生物科技研究院有限公司 一种抗brca1单克隆抗体及其用途
WO2025059215A1 (fr) 2023-09-12 2025-03-20 Aadigen, Llc Méthodes et compositions pour traiter ou prévenir le cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019369A1 (fr) * 1994-01-14 1995-07-20 Vanderbilt University Procede de detection et de traitement du cancer du sein
US5756294A (en) * 1995-09-25 1998-05-26 Oncormed, Inc. Susceptibility mutation for breast and ovarian cancer
US5654155A (en) * 1996-02-12 1997-08-05 Oncormed, Inc. Consensus sequence of the human BRCA1 gene

Also Published As

Publication number Publication date
WO1998001460A1 (fr) 1998-01-15
AU3655097A (en) 1998-02-02
EP0918788A1 (fr) 1999-06-02
EP0918788A4 (fr) 2002-02-13
NZ333635A (en) 2000-06-23
AU736210B2 (en) 2001-07-26
JP2002513272A (ja) 2002-05-08
KR20000023600A (ko) 2000-04-25
CA2259154A1 (fr) 1998-01-15

Similar Documents

Publication Publication Date Title
WO1998010771A8 (fr) Prevention du cancer de l'ovaire par administration de produits a la progestine
WO1999045910A3 (fr) Methodes et compositions pour le traitement et la prevention des mucosites
WO1998015622A8 (fr) Transformation et regeneration de cotonniers fertiles
WO1998024183A8 (fr) Dispositif d'interface de souris pour fournir un retour de force
WO1998010386A8 (fr) Dispositif en forme de disque avec materiau de systeme electronique de surveillance d'articles
WO1998023046A8 (fr) Procede et appareil de notification a marge elevee
WO1998018888A8 (fr) Raffinage d'une huile comestible riche en carotenes naturels et en vitamine e
WO1997020575A8 (fr) Vecteurs adenoviraux cibles
WO1997048032A8 (fr) Corps cellulaire de metallisation programmable et procede de fabrication
WO1998016421A8 (fr) Dispositif de lecture, detection, choix d'objectifs, communication et reponse base sur un aeronef
WO1998000479A8 (fr) Procede d'hydroconversion de raffinat
WO1997025042A8 (fr) Utilisation d'un agoniste de ppar-alpha et de ppar-gamma dans le traitement du syndrome x
WO1998017782A8 (fr) Procede pour produire des modeles animaux transgeniques avec modulation du phenotype, et animaux ainsi obtenus
WO1998023050A3 (fr) Telechargement simultane de donnees par radiodiffusion vers plusieurs emetteurs-recepteurs
WO1999015684A8 (fr) Methode
WO1998016077A8 (fr) Systeme de communication utilisant des donnees de position geographique
WO1997017980A8 (fr) Traitement de la cardiomyopathie par elimination des auto-anticorps
WO1998025264A8 (fr) Micro-actionneur de curseur de bord avant
WO1998022094A3 (fr) Procede de preparation de compositions polyol façonnees ou non façonnees
WO1998023962A8 (fr) Diagnostic de maladies a prions
WO1998015272A8 (fr) Procede d'inhibition de proteines kinases activees par contrainte
WO1996001622A8 (fr) Nouvelle preparation pharmaceutique a administration orale contenant un sel magnesien d'omeprazole
WO1998001460A8 (fr) Compositions brca1 et procedes de diagnostic et de traitement du cancer du sein
WO1998027107A8 (fr) Procede de couplage de polysaccharides a des proteines
WO1998023002A8 (fr) Baie comportant un cadre inferieur et un cadre superieur constitues d'un profile continu

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL

COP Corrected version of pamphlet

Free format text: PAGES 21-85, DESCRIPTION, REPLACED BY NEW PAGES BEARING THE SAME NUMBER; PAGES 6/14 AND 10/14-14/14, DRAWINGS, REPLACED BY NEW PAGES 6/15 AND 10/15-15/15; AFTER RECTIFICATION OF OBVIOUS ERRORS AS AUTHORIZED BY THE INTERNATIONAL SEARCHING AUTHORITY; PAGES 1/14-5/14 AND 7/14-9/14 REPLACED BY NEW PAGES 1/15-5/15 AND 7/15-9/15; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2259154

Country of ref document: CA

Ref country code: CA

Ref document number: 2259154

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 333635

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 1019997000046

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: PA/a/1999/000406

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 1997933344

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1997933344

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09214356

Country of ref document: US

AK Designated states

Kind code of ref document: C1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i
WWP Wipo information: published in national office

Ref document number: 1019997000046

Country of ref document: KR

WWW Wipo information: withdrawn in national office

Ref document number: 1997933344

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1019997000046

Country of ref document: KR

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载