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WO1997006268A3 - Dna constructs - Google Patents

Dna constructs Download PDF

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Publication number
WO1997006268A3
WO1997006268A3 PCT/GB1996/001846 GB9601846W WO9706268A3 WO 1997006268 A3 WO1997006268 A3 WO 1997006268A3 GB 9601846 W GB9601846 W GB 9601846W WO 9706268 A3 WO9706268 A3 WO 9706268A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
gene
insects
encodes
damaging
Prior art date
Application number
PCT/GB1996/001846
Other languages
French (fr)
Other versions
WO1997006268A2 (en
Inventor
Ian Jepson
Jacqueline Ann Mary Paine
Original Assignee
Zeneca Ltd
Ian Jepson
Jacqueline Ann Mary Paine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Ian Jepson, Jacqueline Ann Mary Paine filed Critical Zeneca Ltd
Priority to PL96324880A priority Critical patent/PL324880A1/en
Priority to CA002227445A priority patent/CA2227445A1/en
Priority to APAP/P/1998/001194A priority patent/AP863A/en
Priority to IL12317296A priority patent/IL123172A0/en
Priority to AU66252/96A priority patent/AU704172B2/en
Priority to BR9609873A priority patent/BR9609873A/en
Priority to SK169-98A priority patent/SK16998A3/en
Priority to EP96925889A priority patent/EP0846179A2/en
Priority to MX9801008A priority patent/MX9801008A/en
Priority to JP9508208A priority patent/JPH11510694A/en
Priority to NZ313724A priority patent/NZ313724A/en
Publication of WO1997006268A2 publication Critical patent/WO1997006268A2/en
Publication of WO1997006268A3 publication Critical patent/WO1997006268A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A chemically-inducible plant gene expression cassette comprising a first promoter operatively linked to a regulator sequence which is derived from the alcR gene and encodes a regulator protein, and an inducible promoter operatively linked to a target gene which encodes a protein which is damaging to insects or whose expression induces a metabolic pathway which produces a metabolite which is damaging to insects, the inducible promoter being activated by the regulator protein in the presence of an effective exogenous inducer whereby application of the inducer causes expression of the target gene.
PCT/GB1996/001846 1995-08-08 1996-07-29 Dna constructs WO1997006268A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
PL96324880A PL324880A1 (en) 1995-08-08 1996-07-29 Dna constructs
CA002227445A CA2227445A1 (en) 1995-08-08 1996-07-29 Dna constructs
APAP/P/1998/001194A AP863A (en) 1995-08-08 1996-07-29 Dna constructs.
IL12317296A IL123172A0 (en) 1995-08-08 1996-07-29 Dna constructs
AU66252/96A AU704172B2 (en) 1995-08-08 1996-07-29 DNA constructs
BR9609873A BR9609873A (en) 1995-08-08 1996-07-29 Chemically inducible plant gene expression cassette plant cell plant tissue plant seed and process for controlling insects
SK169-98A SK16998A3 (en) 1995-08-08 1996-07-29 Chemically-inducible plant gene expression cassette
EP96925889A EP0846179A2 (en) 1995-08-08 1996-07-29 Dna constructs
MX9801008A MX9801008A (en) 1995-08-08 1996-07-29 Dna constructs.
JP9508208A JPH11510694A (en) 1995-08-08 1996-07-29 DNA construct
NZ313724A NZ313724A (en) 1995-08-08 1996-07-29 Dna constructs and promoter sequences and their use in the expression of genes which confer insecticidal activity on plants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9516241.8 1995-08-08
GBGB9516241.8A GB9516241D0 (en) 1995-08-08 1995-08-08 Dna constructs

Publications (2)

Publication Number Publication Date
WO1997006268A2 WO1997006268A2 (en) 1997-02-20
WO1997006268A3 true WO1997006268A3 (en) 1997-03-13

Family

ID=10778942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1996/001846 WO1997006268A2 (en) 1995-08-08 1996-07-29 Dna constructs

Country Status (19)

Country Link
EP (1) EP0846179A2 (en)
JP (1) JPH11510694A (en)
KR (1) KR19990036251A (en)
CN (1) CN1199425A (en)
AP (1) AP863A (en)
AR (1) AR002914A1 (en)
AU (1) AU704172B2 (en)
BR (1) BR9609873A (en)
CA (1) CA2227445A1 (en)
CZ (1) CZ36998A3 (en)
GB (1) GB9516241D0 (en)
HU (1) HUP9900057A3 (en)
IL (1) IL123172A0 (en)
MX (1) MX9801008A (en)
NZ (1) NZ313724A (en)
PL (1) PL324880A1 (en)
SK (1) SK16998A3 (en)
TR (1) TR199800177T1 (en)
WO (1) WO1997006268A2 (en)

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GB9606062D0 (en) 1996-03-22 1996-05-22 Zeneca Ltd Promoters
GB9817704D0 (en) * 1998-08-13 1998-10-07 Zeneca Ltd Gene switch
GB9902234D0 (en) * 1999-02-01 1999-03-24 Zeneca Ltd Expression system
GB9902236D0 (en) * 1999-02-01 1999-03-24 Zeneca Ltd Formulation
GB9918154D0 (en) * 1999-08-02 1999-10-06 Zeneca Ltd Expression system
EP1925672A1 (en) 2001-06-22 2008-05-28 Syngeta Participations AG Abiotic stress responsive polynucleotides and polypeptides
DE10212158A1 (en) 2002-03-19 2003-10-02 Metanomics Gmbh & Co Kgaa Population of transgenic plants, derived biological material, corresponding plasmid collection and population of transformed host organisms, as well as their use and methods for their production
CN100552030C (en) 2002-12-20 2009-10-21 梅坦诺米克斯有限及两合公司 Prepare amino acid whose method
EP2322633A3 (en) 2003-02-17 2011-08-17 Metanomics GmbH Preparation of organisms with faster growth and/or higher yield
CN1852985A (en) 2003-08-01 2006-10-25 巴斯福植物科学有限公司 Process for the production of fine chemicals
WO2006069610A2 (en) 2004-07-02 2006-07-06 Metanomics Gmbh Process for the production of fine chemicals
US20100050296A1 (en) 2004-07-31 2010-02-25 Metanomics Gmbh Preparation of organisms with faster growth and/or higher yield
MX2007007040A (en) 2004-12-17 2008-10-24 Metanomics Gmbh Process for the control of production of fine chemicals.
EP2573188A2 (en) 2005-03-02 2013-03-27 Metanomics GmbH Process for the production of fine chemicals
AU2006219823A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
EP2166102B1 (en) 2005-03-08 2012-12-19 BASF Plant Science GmbH Expression enhancing intron sequences
BRPI0612710A2 (en) 2005-07-06 2012-10-02 Cropdesign Nv method for increasing plant yield over control plants, and for producing a transgenic plant having increased yield, plant, construction, collectable parts of a plant, products, and use of a ste20 type gene or variant or variant or use a ste20-like polypeptide or its counterpart
CA2621489A1 (en) 2005-09-15 2007-03-22 Cropdesign N.V. Plant yield improvement by group 3 lea expression
EP2199398A1 (en) 2006-03-31 2010-06-23 BASF Plant Science GmbH Plants having enhanced yield-related traits and a method for making the same
CA2644273A1 (en) 2006-04-05 2008-03-27 Metanomics Gmbh Process for the production of a fine chemical
MX2008015090A (en) 2006-05-31 2008-12-15 Metanomics Gmbh Manipulation of the nitrogen metabolism using ammonium transporter or glucose 6-phosphate deshydrogenases or farnesyl phosphate synthetase (fpp).
CA2649341A1 (en) 2006-06-08 2007-12-13 Basf Plant Science Gmbh Plants having improved growth characteristics and method for making the same
EP2540832A1 (en) 2006-08-02 2013-01-02 CropDesign N.V. Plants transformed with a small inducible kinase having improved yield related traits and a method for making the same
ITUD20060280A1 (en) 2006-12-29 2008-06-30 Univ Degli Studi Udine ARTIFICIAL SEQUENCE OF DNA EVENT FUNCTION OF LEADER IN 5 '(5'-UTR) OPTIMIZED FOR THE OVEREXPRESSION OF HETEROLOGICAL PLANT PROTEINS
EP2492345A3 (en) 2007-05-04 2012-12-12 BASF Plant Science GmbH Seed enhancement by combinations of pyruvate kinases
EP2074220A2 (en) 2007-05-22 2009-07-01 BASF Plant Science GmbH Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-ko
CA2704271C (en) 2007-12-03 2016-07-19 Syngenta Participations Ag Engineering enzymatically susceptible phytases
AU2008340002A1 (en) 2007-12-21 2009-07-02 Basf Plant Science Gmbh Plants with increased yield (KO NUE)
WO2011074959A1 (en) 2009-12-15 2011-06-23 Edwin Henricus Antonius Holman Transgenic ozone-resistant plants
AR083029A1 (en) 2010-12-09 2013-01-23 Syngenta Participations Ag METHODS AND COMPOSITIONS THAT USE SMALL INTERFERENT ARN (ARNIP) FOR THE CONTROL OF NEMATODES IN PLANTS
CN103314115A (en) 2011-01-18 2013-09-18 先正达参股股份有限公司 Methods and compositions for modified ethanol inducible promoter systems
US8951752B2 (en) 2011-10-20 2015-02-10 University Of Iowa Research Foundation N-demethyase genes and uses thereof
ES2670505T3 (en) 2012-02-16 2018-05-30 Syngenta Participations Ag Modified Pesticide Proteins
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WO1993007278A1 (en) * 1991-10-04 1993-04-15 Ciba-Geigy Ag Synthetic dna sequence having enhanced insecticidal activity in maize
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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
EP0159884A2 (en) * 1984-04-13 1985-10-30 Lubrizol Genetics Inc. Heat shock promoter and gene
WO1993007278A1 (en) * 1991-10-04 1993-04-15 Ciba-Geigy Ag Synthetic dna sequence having enhanced insecticidal activity in maize
WO1993021334A1 (en) * 1992-04-13 1993-10-28 Zeneca Limited Dna constructs and plants incorporating them
WO1995014098A1 (en) * 1993-11-19 1995-05-26 Biotechnology Research And Development Corporation Chimeric regulatory regions and gene cassettes for expression of genes in plants

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Title
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Also Published As

Publication number Publication date
KR19990036251A (en) 1999-05-25
CZ36998A3 (en) 1998-06-17
AP9801194A0 (en) 1998-03-31
EP0846179A2 (en) 1998-06-10
AU6625296A (en) 1997-03-05
TR199800177T1 (en) 1998-05-21
JPH11510694A (en) 1999-09-21
AP863A (en) 2000-08-04
WO1997006268A2 (en) 1997-02-20
AU704172B2 (en) 1999-04-15
CN1199425A (en) 1998-11-18
GB9516241D0 (en) 1995-10-11
MX9801008A (en) 1998-04-30
AR002914A1 (en) 1998-04-29
IL123172A0 (en) 1998-09-24
SK16998A3 (en) 1998-09-09
HUP9900057A3 (en) 2001-06-28
CA2227445A1 (en) 1997-02-20
HUP9900057A2 (en) 1999-04-28
PL324880A1 (en) 1998-06-22
BR9609873A (en) 1999-03-23
NZ313724A (en) 1999-04-29

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