+

WO1996017585A1 - Preparation pour empecher d'une maniere permanente la repousse des poils - Google Patents

Preparation pour empecher d'une maniere permanente la repousse des poils Download PDF

Info

Publication number
WO1996017585A1
WO1996017585A1 PCT/GB1995/002709 GB9502709W WO9617585A1 WO 1996017585 A1 WO1996017585 A1 WO 1996017585A1 GB 9502709 W GB9502709 W GB 9502709W WO 9617585 A1 WO9617585 A1 WO 9617585A1
Authority
WO
WIPO (PCT)
Prior art keywords
hair
growth
hair growth
permanent hair
breaker composition
Prior art date
Application number
PCT/GB1995/002709
Other languages
English (en)
Inventor
Sultan Daham
Original Assignee
Al-Ramadhani, Nabeel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Al-Ramadhani, Nabeel filed Critical Al-Ramadhani, Nabeel
Priority to AU38768/95A priority Critical patent/AU3876895A/en
Publication of WO1996017585A1 publication Critical patent/WO1996017585A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A61Q7/02—Preparations for inhibiting or slowing hair growth

Definitions

  • the present invention relates to the permanent prevention of undesired hair growth and, in particular, to a preparation and method for the permanent prevention of undesired hair growth on the face or body.
  • the most widely used methods of undesired hair removal can be divided into two categories. In the first of these, the upper part of the hair is removed either chemically or mechanically and the lower part remains intact beneath the skin. Examples of this first category include the use of depilatory preparations based on thiogiycollate, analogues thereof or similarly-acting compounds, and shaving. Hair removed by this method re-grows within a few days.
  • the second category of undesired hair removal is characterised in that the hair is plucked from its roots.
  • European Patent Application No. 0 532 219 is concerned with many different compositions suitable for topical application to mammalian skin for affecting hair growth in various ways.
  • This document acknowledges that an effective amount of the composition and frequency of application to the skin varies from person to person.
  • a daily topical application of 0.00001 to 1 g of a glutamine metabolism inhibitor will, in most cases, maintain the skin in a hairless condition.
  • this document teaches prophylactic treatment and does not provide a permanent solution to the user.
  • the invention recognises, for the first time, that the combination of zinc or its salts and copper or its salts in a single formulation is effective to prevent hair re-growth on a permanent basis, when applied to an area of skin from which the hair has previously been plucked from its roots.
  • a permanent hair growth-breaker composition effective to preventthe re-growth of undesired hair which is plucked from its roots using any suitable method such as waxing, sugaring, plucking with tweezers or a mechanical device which grasps the hair and plucks it from the roots, as described above, said composition comprising a combination of the two active ingredients identified below in a single formulation in the stated proportions: zinc (elemental or as salt) 0.0001 to 10 g/100ml copper (elemental or as salt) 0.0001 to 10 g/100ml and further comprising excipient to a total volume of 100ml.
  • the permanent hair growth breaker has the active constituents combined together in a single formulation in the following proportions: zinc sulphate 0.0001 to 3.0 g/100ml copper sulphate 0.0001 to 3.0 g/100ml and further comprises excipient to a total volume of 100ml.
  • Figure 1 is a graph showing the effect of the invention on the proportion of undesired hair growth prevention compared to compositions having only one of the active constituents in non-human mammals, and
  • Figure 2 is a graph showing the effect of the invention on the proportion of undesired hair growth prevention compared to compositions having only one of the active constituents in human volunteers.
  • the permanent hair growth-breaker composition is applied immediately to the part of the body from which undesired hair has been plucked from its roots.
  • the composition should be left in place for a number of hours and then removed by washing with soap and water.
  • the effect of permanently preventing re-growth of undesired hair which has been plucked from its roots may be achieved after a single application of the permanent hair growth-breaker composition. If necessary, however, the process can be repeated, typically three or four times, until the desired effect of permanent prevention of hair re-growth is achieved. It is usually the case that application of the composition for the first time after removing hair by plucking it from its roots has a marked impact.
  • the percentage of success in permanent prevention of hair re-growth for sugar/citric acid- depleted hair was 75%.
  • a thioglycollate preparation for hair removed using a thioglycollate preparation, there was only a delay in hair re-growth, rather than permanent prevention thereof. Moreover, such delay was only observed in 20% of cases. It is therefore clear that the method of hair removal preparatory to application of the inventive composition is also influential upon the level of success.
  • the composition may be applied in the form of an aqueous solution, a lotion, cream, ointment, gel or similar preparation.
  • the composition may be formulated in any suitable vehicle which enables the two active ingredients combined together to be dissolved or held in suspension to facilitate application to the skin after plucking out the undesired hair from its roots.
  • Any liquid or semi-liquid preparation which contains the two active ingredients combined together may also include suitable anti-microbial preservatives in keeping with normal pharmaceutical practice.
  • the formulation may further include a viscosity builder to thicken the product for improved consumer acceptance. Fragrances and/or colouring additives are further optional constituents which may be included to enhance customer acceptance.
  • the formulation may also comprise emollient/humectant constituents to improve skin feel, as well as stabilisers such as EDTA which are effective to reduce any formulation interaction with added essential oil fragrance.
  • the composition is formulated at a pH which enables the combination of the two active ingredients to be stabilised.
  • the formulation is rendered mildly basic, for example having a pH which falls in the range 8.5 to 10.5.
  • the composition is thought to exert its preventative effect by interaction with hair growth factors released by the hair dermal papilla cells (DPC). These growth factors stimulate hair growth in normal, healthy hair. By plucking the hair from its roots, an improved pathway is provided whereby the combination of active ingredients in the composition is enabled to reach the hair DPC and break the effect of the growth factors. No other forms of hair removal (e.g. shaving or dissolution with depilatory creams) are effective in this regard, since the surviving hair stem blocks the pathway for the combined active ingredients and prevents them from reaching the hair DPC in an effective amount.
  • DPC hair dermal papilla cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

Une composition pour empêcher d'une manière permanente la repousse des poils indésirables, que l'on a auparavant arrachés avec leur racine, contient deux ingrédients actifs combinés ensemble dans les proportions suivantes: zinc (élémentaire ou sous la forme d'un sel) 0,0001 à 10 g/100 m, cuivre (élémentaire ou sous forme d'un sel) 0,0001 à 10 g/100 ml, et un excipient jusqu'à concurrence d'un de 100 ml. La préparation peut être formulée comme solution, lotion, crème, onguent, gel ou similaire, pour qu'elle puisse rester pendant une durée prédéterminée sur la peau où elle a été appliquée. Parmi les composants facultatifs, on peut citer les agents pour augmenter la viscosité (épaississants); les agents émollients/hydratants pour assouplir la peau, les stabilisants pour diminuer l'interaction avec les autres constituants, les huiles essentielles (parfum) et les agents colorants. On élimine les poils indésirables avec les racines, par exemple en utilisant une cire, un caramel, des pinces à épiler ou un appareil d'épilation mécanique spécial. Lorsque cela est nécessaire, l'épilation et l'application de la composition peuvent être répétées plusieurs fois jusqu'à ce que la repousse soit définitivement empêchée.
PCT/GB1995/002709 1994-12-06 1995-11-17 Preparation pour empecher d'une maniere permanente la repousse des poils WO1996017585A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU38768/95A AU3876895A (en) 1994-12-06 1995-11-17 Permanent hair growth-breaker

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9424828.3A GB9424828D0 (en) 1994-12-06 1994-12-06 Hair removal preparation
GB9424828.3 1994-12-06

Publications (1)

Publication Number Publication Date
WO1996017585A1 true WO1996017585A1 (fr) 1996-06-13

Family

ID=10765642

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1995/002709 WO1996017585A1 (fr) 1994-12-06 1995-11-17 Preparation pour empecher d'une maniere permanente la repousse des poils

Country Status (3)

Country Link
AU (1) AU3876895A (fr)
GB (1) GB9424828D0 (fr)
WO (1) WO1996017585A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627624A1 (fr) 2004-08-17 2006-02-22 L'oreal Composition topique comprenant des particules poreuses chargées et un composé absorbant le sébum

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2380775A1 (fr) * 1977-02-22 1978-09-15 Sederma Sarl Composition " apres-epilation " favorisant un ralentissement progressif de la repousse des poils
FR2587208A1 (fr) * 1985-09-19 1987-03-20 Scherninski Francois Lotion antichute et regeneratrice capillaire
EP0302265A1 (fr) * 1987-08-07 1989-02-08 Wella Aktiengesellschaft Agent pour onduler ou épiler les cheveux
EP0532219A2 (fr) * 1991-09-04 1993-03-17 Unilever Plc Composition cosmétique
WO1993008791A1 (fr) * 1991-10-31 1993-05-13 The Boots Company Plc Compositions depilatoires
WO1994021216A1 (fr) * 1993-03-19 1994-09-29 Handelman, Joseph, H. Compositions topiques destinees a inhiber la pousse des poils

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2380775A1 (fr) * 1977-02-22 1978-09-15 Sederma Sarl Composition " apres-epilation " favorisant un ralentissement progressif de la repousse des poils
FR2587208A1 (fr) * 1985-09-19 1987-03-20 Scherninski Francois Lotion antichute et regeneratrice capillaire
EP0302265A1 (fr) * 1987-08-07 1989-02-08 Wella Aktiengesellschaft Agent pour onduler ou épiler les cheveux
EP0532219A2 (fr) * 1991-09-04 1993-03-17 Unilever Plc Composition cosmétique
WO1993008791A1 (fr) * 1991-10-31 1993-05-13 The Boots Company Plc Compositions depilatoires
WO1994021216A1 (fr) * 1993-03-19 1994-09-29 Handelman, Joseph, H. Compositions topiques destinees a inhiber la pousse des poils

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627624A1 (fr) 2004-08-17 2006-02-22 L'oreal Composition topique comprenant des particules poreuses chargées et un composé absorbant le sébum

Also Published As

Publication number Publication date
GB9424828D0 (en) 1995-02-08
AU3876895A (en) 1996-06-26

Similar Documents

Publication Publication Date Title
KR100341300B1 (ko) 장미씨 기름을 함유하는 치약조성물
JP3768233B2 (ja) 毛髪成長の抑制
US6479043B1 (en) Depilatory composition
CA1325383C (fr) Traitement du cuir chevelu
US5217711A (en) Hair care system
WO2001093817A1 (fr) Compositions cosmetiques destinees au soin du cuir chevelu et des cheveux
WO2008034178A1 (fr) Composition dépilatoire topique
US5750107A (en) Hair growth promoter
AU664602B2 (en) Hair growth and restoration promoter
JPH03188019A (ja) テストステロン―５α―レダクターゼ阻害剤
JPH03227911A (ja) 育毛剤
JPH1143422A (ja) 毛髪化粧料
US6271260B1 (en) Prevention/retardation of hair growth
GB2326335A (en) Composition for the prevention of hair re-growth
WO1996017585A1 (fr) Preparation pour empecher d'une maniere permanente la repousse des poils
GB2341091A (en) Essential oil composition for treatment of head-lice
GB2295771A (en) Composition for the prevention of hair growth
CA2053089C (fr) Systeme de soins capillaires
JPH0853327A (ja) アラントインまたはその誘導体による養毛・育毛剤
JPH0615462B2 (ja) 毛髪用組成物
FR2680104A1 (fr) Composition cosmetique comprenant des herbes officinales et son procede de preparation.
JPH01242516A (ja) 養毛剤、養毛シャンプー及び養毛促進剤
JP2702794B2 (ja) 毛髪付着塩素除去剤
JPH04193821A (ja) 養毛化粧料
JPH0525024A (ja) シヤンプー

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AM AU BB BG BR BY CA CN CZ EE FI GE HU IS JP KE KG KP KR KZ LK LR LT LV MD MG MK MN MW MX NO NZ PL RO RU SD SG SI SK TJ TM TT UA UG US UZ VN

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载