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WO1993003841A1 - Echangeur d'ions, sa fabrication et procede pour separer un biopolymere a l'aide de celui-ci - Google Patents

Echangeur d'ions, sa fabrication et procede pour separer un biopolymere a l'aide de celui-ci Download PDF

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Publication number
WO1993003841A1
WO1993003841A1 PCT/JP1992/001061 JP9201061W WO9303841A1 WO 1993003841 A1 WO1993003841 A1 WO 1993003841A1 JP 9201061 W JP9201061 W JP 9201061W WO 9303841 A1 WO9303841 A1 WO 9303841A1
Authority
WO
WIPO (PCT)
Prior art keywords
cross
linked
ion exchanger
production
pores
Prior art date
Application number
PCT/JP1992/001061
Other languages
English (en)
Japanese (ja)
Inventor
Keiko Kudo
Hideaki Kiniwa
Original Assignee
Mitsubishi Kasei Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corporation filed Critical Mitsubishi Kasei Corporation
Publication of WO1993003841A1 publication Critical patent/WO1993003841A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

Sont décrits un échangeur d'ions comprenant un composite présentant un degré de gonflement dans l'eau de 2 à 7 ml/g de résine, ledit composite étant préparé par le maintien d'un gel réticulé, lequel comprend une macromolécule naturelle hydrophile possédant une structure réticulée tridimensionnelle et comporte des groupes échangeurs d'ions, dans les pores d'une particule poreuse d'un copolymère réticulé hydrophile présentant des pores d'un diamètre de 0,01 à moins de 1 νm, un volume de pores de 30 à 70 % du volume de résine et de préférence un diamètre particulaire de 5 à 500 νm; un procédé pour sa production; et un procédé pour séparer des biopolymères tels que des protéines à l'aide dudit échangeur d'ions. Cet échangeur subit peu de variations de volume, sert à remédier aux insuffisances des gels réticulés classiques lors du passage de divers liquides, et offre l'avantage d'être exempt d'adsorption non spécifique et d'avoir des taux élevés d'adsorption et de désorption dans la séparation de biopolymères tels que des protéines.
PCT/JP1992/001061 1991-08-23 1992-08-24 Echangeur d'ions, sa fabrication et procede pour separer un biopolymere a l'aide de celui-ci WO1993003841A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21229691 1991-08-23
JP3/212296 1991-08-23

Publications (1)

Publication Number Publication Date
WO1993003841A1 true WO1993003841A1 (fr) 1993-03-04

Family

ID=16620234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1992/001061 WO1993003841A1 (fr) 1991-08-23 1992-08-24 Echangeur d'ions, sa fabrication et procede pour separer un biopolymere a l'aide de celui-ci

Country Status (1)

Country Link
WO (1) WO1993003841A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013011632A (ja) * 2012-10-19 2013-01-17 Sekisui Chem Co Ltd ヘモグロビンＡ１ｃの測定方法
JP2013515258A (ja) * 2009-12-22 2013-05-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ クロマトグラフィーカラムを乾式充填する方法
JP2017125796A (ja) * 2016-01-15 2017-07-20 日立化成株式会社 分離材及びカラム
JP2017125814A (ja) * 2016-01-15 2017-07-20 日立化成株式会社 分離材及びカラム
JP2019177509A (ja) * 2018-03-30 2019-10-17 株式会社リコー ハイドロゲル構造体、その製造方法、及び臓器モデル
JP2021069991A (ja) * 2019-10-31 2021-05-06 昭和電工株式会社 糖化ヘモグロビン分析用カラムの充填剤の製造方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01254247A (ja) * 1988-04-01 1989-10-11 Mitsubishi Kasei Corp 複合化分離剤及びその製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01254247A (ja) * 1988-04-01 1989-10-11 Mitsubishi Kasei Corp 複合化分離剤及びその製造法

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013515258A (ja) * 2009-12-22 2013-05-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ クロマトグラフィーカラムを乾式充填する方法
US9958421B2 (en) 2009-12-22 2018-05-01 Ge Healthcare Bioprocess R&D Ab Method for dry packing chromatography columns
JP2013011632A (ja) * 2012-10-19 2013-01-17 Sekisui Chem Co Ltd ヘモグロビンＡ１ｃの測定方法
JP2017125796A (ja) * 2016-01-15 2017-07-20 日立化成株式会社 分離材及びカラム
JP2017125814A (ja) * 2016-01-15 2017-07-20 日立化成株式会社 分離材及びカラム
JP2019177509A (ja) * 2018-03-30 2019-10-17 株式会社リコー ハイドロゲル構造体、その製造方法、及び臓器モデル
JP2021069991A (ja) * 2019-10-31 2021-05-06 昭和電工株式会社 糖化ヘモグロビン分析用カラムの充填剤の製造方法

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