WO1990005520A3 - Traitement antiviral de cultures de tissus et compositions - Google Patents
Traitement antiviral de cultures de tissus et compositions Download PDFInfo
- Publication number
- WO1990005520A3 WO1990005520A3 PCT/US1989/005022 US8905022W WO9005520A3 WO 1990005520 A3 WO1990005520 A3 WO 1990005520A3 US 8905022 W US8905022 W US 8905022W WO 9005520 A3 WO9005520 A3 WO 9005520A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue culture
- compositions
- processes
- antiviral processes
- culture antiviral
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000012894 fetal calf serum Substances 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000003104 tissue culture media Substances 0.000 abstract 1
- 150000003648 triterpenes Chemical class 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
On décrit des substances nutritives, telles que le sérum de veau f÷tal, pour les milieux de culture de tissus, comprenant un sérum et un ou plusieurs composés triterpenoïdes glycyrrhiziques, capables d'inactiver le cytomégalovirus (CMV), le virus de diarrhée bovine (BVD) et autres virus spécifiques, ainsi que des procédés permettant de protéger lesdites cultures de tissus des infections virales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27611388A | 1988-11-23 | 1988-11-23 | |
US276,113 | 1988-11-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1990005520A2 WO1990005520A2 (fr) | 1990-05-31 |
WO1990005520A3 true WO1990005520A3 (fr) | 1990-07-12 |
Family
ID=23055226
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1989/005025 WO1990005547A1 (fr) | 1988-11-23 | 1989-11-08 | Procede de traitement antiviral du sperme |
PCT/US1989/005023 WO1990005533A1 (fr) | 1988-11-23 | 1989-11-08 | Albumine biologiquement competente, capable d'inactiver un virus |
PCT/US1989/005024 WO1990005546A1 (fr) | 1988-11-23 | 1989-11-08 | Amelioration du procede antiviral d'echantillonnage de sang et son appareil |
PCT/US1989/005021 WO1990005550A1 (fr) | 1988-11-23 | 1989-11-08 | Traitement antiviral applique aux organes de transplantation |
PCT/US1989/005022 WO1990005520A2 (fr) | 1988-11-23 | 1989-11-08 | Traitement antiviral de cultures de tissus et compositions |
PCT/US1989/005117 WO1990005548A1 (fr) | 1988-11-23 | 1989-11-13 | Procede et produit sanguin d'inactivation d'un virus |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1989/005025 WO1990005547A1 (fr) | 1988-11-23 | 1989-11-08 | Procede de traitement antiviral du sperme |
PCT/US1989/005023 WO1990005533A1 (fr) | 1988-11-23 | 1989-11-08 | Albumine biologiquement competente, capable d'inactiver un virus |
PCT/US1989/005024 WO1990005546A1 (fr) | 1988-11-23 | 1989-11-08 | Amelioration du procede antiviral d'echantillonnage de sang et son appareil |
PCT/US1989/005021 WO1990005550A1 (fr) | 1988-11-23 | 1989-11-08 | Traitement antiviral applique aux organes de transplantation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1989/005117 WO1990005548A1 (fr) | 1988-11-23 | 1989-11-13 | Procede et produit sanguin d'inactivation d'un virus |
Country Status (5)
Country | Link |
---|---|
US (4) | US4891221A (fr) |
EP (2) | EP0399027A1 (fr) |
JP (2) | JPH03503287A (fr) |
AU (6) | AU4636589A (fr) |
WO (6) | WO1990005547A1 (fr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5112804A (en) * | 1987-04-01 | 1992-05-12 | Temple University Of The Commonwealth System Of Higher Education | Pharmaceutical composition and method of intranasal administration |
JPH01175942A (ja) * | 1987-12-28 | 1989-07-12 | Sanyo Kokusaku Pulp Co Ltd | 抗ウイルス性医薬用組成物 |
US5248501A (en) * | 1988-11-22 | 1993-09-28 | Parnell Pharmaceuticals | Drug delivery systems containing eriodictyon fluid extract as an excipient, and methods and compositions associated therewith |
US5128132A (en) * | 1988-11-22 | 1992-07-07 | Parnell Pharmaceuticals, Inc. | Eriodictyon compositions and methods for treating internal mucous membranes |
US5156973A (en) * | 1988-11-23 | 1992-10-20 | Edward Shanbrom | Antiviral blood sampling process and apparatus |
US5149718A (en) * | 1989-01-19 | 1992-09-22 | New York University | Biological fluid purification system |
US5562608A (en) * | 1989-08-28 | 1996-10-08 | Biopulmonics, Inc. | Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation |
EP0530216A4 (en) * | 1990-04-19 | 1993-06-30 | Medimmune, Inc. | Administration of monoclonal antibodies against respiratory viruses |
ATE175123T1 (de) * | 1990-07-19 | 1999-01-15 | Us Commerce | Verbesserte immunotherapeutische methode zur verhinderung oder behandlung viraler krankheiten der atemwege |
US5316768A (en) * | 1990-12-28 | 1994-05-31 | Murdock International Corporation | Pharmaceutical compositions having antiviral activity against human cytomegalovirus |
US5290540A (en) * | 1991-05-01 | 1994-03-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for treating infectious respiratory diseases |
USRE37525E1 (en) | 1991-05-01 | 2002-01-22 | Henry M. Jackson Foundation | Method for treating infectious respiratory diseases |
US5356880A (en) * | 1991-05-30 | 1994-10-18 | Sanwa Kagaku Kenkyusho Co., Ltd. | Glycyrrhetinic acid derivatives |
US5792835A (en) * | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
US6207107B1 (en) | 1992-10-05 | 2001-03-27 | Baxter International Inc. | Steam sterilizable system for inactivating viral contaminants in body fluids |
US5591350A (en) * | 1994-04-15 | 1997-01-07 | Pall Corporation | Iodine disinfection method using a gaseous iodine treated porous medium |
US5797871A (en) * | 1994-08-19 | 1998-08-25 | Lifenet Research Foundation | Ultrasonic cleaning of allograft bone |
US5556379A (en) * | 1994-08-19 | 1996-09-17 | Lifenet Research Foundation | Process for cleaning large bone grafts and bone grafts produced thereby |
US5977034A (en) * | 1994-08-19 | 1999-11-02 | Lifenet Research Foundation | Composition for cleaning bones |
US5976104A (en) * | 1994-08-19 | 1999-11-02 | Lifenet Research Foundation | Recirculation method for cleaning essentially intact bone grafts using pressure mediated flow of solutions and bone grafts produced thereby |
US5760189A (en) * | 1995-06-02 | 1998-06-02 | Genetics Institute, Inc. | Protein recovery & purification methods |
GB9517622D0 (en) * | 1995-08-29 | 1995-11-01 | Univ Edinburgh | Regulation of intracellular glucocorticoid concentrations |
TW505653B (en) * | 1996-02-26 | 2002-10-11 | Meiji Seika Co | Triterpene derivatives possessing an effect of treating liver diseases and pharmacentical compositions containing the same |
US5881720A (en) * | 1997-04-29 | 1999-03-16 | The Procter & Gamble Company | Method of delivering halotherapy |
US5916919A (en) * | 1997-06-27 | 1999-06-29 | Dalhousie University | Retrovirus protease inhibitors |
US6045787A (en) * | 1998-09-01 | 2000-04-04 | Shanbrom Technologies Llc | Protection of labile proteins during iodine disinfection |
GB9902000D0 (en) | 1999-01-30 | 1999-03-17 | Delta Biotechnology Ltd | Process |
US6323183B1 (en) * | 1999-06-02 | 2001-11-27 | Ornella Flore | Composition for and method of treatment using triterpenoids |
FI113942B (fi) * | 2000-08-18 | 2004-07-15 | Control Ox Oy | Kasviperäisten fenolisten yhdisteiden käyttö valmistettaessa klamydiainfektion hoidossa ja ennaltaehkäisyssä käyttökelpoista farmaseuttista valmistetta, terveyteen myönteisesti vaikuttavaa ravintoainekoostumusta tai koostumusta lisättäväksi tällaisiin elintarvikkeisiin |
TWI282275B (en) * | 2000-08-17 | 2007-06-11 | Control Ox Oy | Plant-derived and synthetic phenolic compounds and plant extracts, effective in the treatment and prevention of chlamydial infections |
AU2002308648A1 (en) * | 2001-05-04 | 2002-11-18 | Theralife, Inc. | Compositions and methods for reducing cytotoxicity and inhibiting angiogenesis |
EP1397149A1 (fr) * | 2001-06-18 | 2004-03-17 | S.A.V Virex Co Ltd | Extrait de nerium oleander, compositions contenant cet extrait de nerium oleander l. et procede permettant de preparer cet extrait |
US20030163147A1 (en) * | 2002-02-22 | 2003-08-28 | Rabiner Robert A. | Apparatus and method for using a vascular introducer with an ultrasonic probe |
EP2324838A1 (fr) | 2005-09-12 | 2011-05-25 | Abela Pharmaceuticals, Inc. | Compositions comprenant du diméthylsulfoxyde |
US7955418B2 (en) | 2005-09-12 | 2011-06-07 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (DMSO) or related compounds or odors associated with same |
US8435224B2 (en) | 2005-09-12 | 2013-05-07 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds |
ITRM20060163A1 (it) * | 2006-03-24 | 2007-09-25 | Ist Farmacoterapico It Spa | Composizione spray ad uso topico per il tratamento e la prevenzione delle infezioni labiali da herpes simplex |
US20080124395A1 (en) * | 2006-06-22 | 2008-05-29 | Weiliam Chen | Formulations and devices for treatment or prevention of neural ischemic damage |
US8226964B2 (en) * | 2006-09-07 | 2012-07-24 | Biolargo Life Technologies, Inc. | Systems and methods for cleaning liquid carriers related applications data |
US8021610B2 (en) * | 2006-09-07 | 2011-09-20 | Biolargo Life Technologies, Inc. | Systems providing antimicrobial activity to an environment |
US20080063560A1 (en) * | 2006-09-07 | 2008-03-13 | Biolargo Life Technologies, Incorporated | Ground treatment for reducing microbial content |
US9414601B2 (en) * | 2006-09-07 | 2016-08-16 | Biolargo Life Technologies, Incorporated | Material having antimicrobial activity when wet |
US7943158B2 (en) * | 2006-09-07 | 2011-05-17 | BioLargo Life Technologies, Inc | Absorbent systems providing antimicrobial activity |
US20080306610A1 (en) * | 2007-06-07 | 2008-12-11 | Zimmer Orthobiologics, Inc. | Tissue processing for nonimmunogenic implants |
US9839609B2 (en) * | 2009-10-30 | 2017-12-12 | Abela Pharmaceuticals, Inc. | Dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) formulations to treat osteoarthritis |
RU2429227C1 (ru) * | 2010-04-08 | 2011-09-20 | Учреждение Российской академии наук Институт технической химии Уральского отделения РАН | АЦЕТИЛГИДРАЗОН 1-ЦИАНО-19β,28-ЭПОКСИ-2,3-СЕКО-18α-ОЛЕАН-3-АЛЯ, ПРОЯВЛЯЮЩИЙ ИНГИБИРУЮЩУЮ АКТИВНОСТЬ В ОТНОШЕНИИ ВИРУСА ВЕЗИКУЛЯРНОГО СТОМАТИТА ШТАММ "ИНДИАНА" |
WO2012019991A1 (fr) * | 2010-08-09 | 2012-02-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédés et compositions pharmaceutiques pour le traitement des infections par le vih-1 |
WO2012026928A1 (fr) * | 2010-08-25 | 2012-03-01 | Diacarta Llc | Utilisation d'acide glycyrrhétinique, d'acide glycyrrhizique et de composés associés pour prévention et/ou traitement de fibrose pulmonaire |
US9416151B2 (en) | 2010-08-25 | 2016-08-16 | Lurong ZHANG | Use of glycyrrhetinic acid, glycyrrhizic acid and related compounds for prevention and/or treatment of pulmonary fibrosis |
US8435305B2 (en) | 2010-08-31 | 2013-05-07 | Zimmer, Inc. | Osteochondral graft delivery device and uses thereof |
EP2726606A1 (fr) * | 2011-06-28 | 2014-05-07 | Leukocare Ag | Nouveau procédé de stabilisation pour des virus ou bactéries |
WO2013023362A1 (fr) * | 2011-08-16 | 2013-02-21 | 深圳市卫武光明生物制品有限公司 | Immunoglobuline dirigée contre le cytomégalovirus humain pour injection intraveineuse et son procédé de préparation |
WO2016086060A1 (fr) * | 2014-11-26 | 2016-06-02 | The J. David Gladstone Institutes | Procédés pour traiter une infection à cytomégalovirus |
WO2017177966A1 (fr) * | 2016-04-15 | 2017-10-19 | 正大天晴药业集团股份有限公司 | Préparation à inhaler d'acide isoglycyrrhizique ou d'un sel de celui-ci et utilisation dans la préparation de médicaments pour traiter des maladies du système respiratoire |
EP3888662A1 (fr) * | 2020-04-02 | 2021-10-06 | Vossensteyn | Composés, compositions et dispositifs destinés à être utilisés dans le traitement d'infections à coronavirus |
EP4216975A4 (fr) * | 2020-09-25 | 2024-09-04 | Laila Nutraceuticals | Compositions à base de plantes synergiques pour l'immunité, le rhume et la toux |
MX2021005280A (es) | 2021-05-04 | 2022-02-23 | Spv Timser S A P I De C V | Composicion farmaceutica que contiene triterpenoides pentaciclicos. |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2140809A (en) * | 1983-06-01 | 1984-12-05 | Biorex Laboratories Ltd | New derivatives of glycyrrhetinic acid |
EP0249557A1 (fr) * | 1986-06-12 | 1987-12-16 | Fondation Centre National De Transfusion Sanguine | Milieu de culture comportant de l'albumine humaine, procédé de préparation d'un produit injectable à partir de ce milieu, produit obtenu et son utilisation, composition obtenue |
EP0255420A2 (fr) * | 1986-07-26 | 1988-02-03 | Minophagen Pharmaceutical Company | Agent antiviral d'inhibition de la croissance du virus du syndrome immuno-deficitaire acquis (SIDA) |
DE3733181C1 (de) * | 1987-10-01 | 1989-01-19 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines hochreinen,virussicheren,biologisch aktiven Transferrinpraeparates |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1390683A (en) * | 1972-12-18 | 1975-04-16 | Biorex Laboratories Ltd | Pharmaceutical composition |
GB1555796A (en) * | 1976-10-15 | 1979-11-14 | Unilever Ltd | Composition for treating acne |
US4699789A (en) * | 1985-09-27 | 1987-10-13 | Eastern Artificial Insemination Cooperative, Inc. | Viral free semen and methods of producing the same |
-
1988
- 1988-12-28 US US07/290,161 patent/US4891221A/en not_active Expired - Lifetime
-
1989
- 1989-03-09 US US07/321,521 patent/US4933169A/en not_active Expired - Lifetime
- 1989-10-20 US US07/424,682 patent/US5128149A/en not_active Expired - Lifetime
- 1989-10-23 US US07/425,466 patent/US5128150A/en not_active Expired - Lifetime
- 1989-11-08 WO PCT/US1989/005025 patent/WO1990005547A1/fr unknown
- 1989-11-08 AU AU46365/89A patent/AU4636589A/en not_active Abandoned
- 1989-11-08 JP JP2500391A patent/JPH03503287A/ja active Pending
- 1989-11-08 WO PCT/US1989/005023 patent/WO1990005533A1/fr not_active Application Discontinuation
- 1989-11-08 AU AU45252/89A patent/AU4525289A/en not_active Abandoned
- 1989-11-08 WO PCT/US1989/005024 patent/WO1990005546A1/fr unknown
- 1989-11-08 WO PCT/US1989/005021 patent/WO1990005550A1/fr unknown
- 1989-11-08 AU AU46539/89A patent/AU4653989A/en not_active Abandoned
- 1989-11-08 AU AU46649/89A patent/AU4664989A/en not_active Abandoned
- 1989-11-08 EP EP90900468A patent/EP0399027A1/fr not_active Ceased
- 1989-11-08 AU AU45250/89A patent/AU4525089A/en not_active Abandoned
- 1989-11-08 WO PCT/US1989/005022 patent/WO1990005520A2/fr unknown
- 1989-11-13 EP EP90900524A patent/EP0406369A1/fr not_active Ceased
- 1989-11-13 JP JP2500750A patent/JPH03503170A/ja active Pending
- 1989-11-13 WO PCT/US1989/005117 patent/WO1990005548A1/fr not_active Application Discontinuation
- 1989-11-13 AU AU47503/90A patent/AU4750390A/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2140809A (en) * | 1983-06-01 | 1984-12-05 | Biorex Laboratories Ltd | New derivatives of glycyrrhetinic acid |
EP0249557A1 (fr) * | 1986-06-12 | 1987-12-16 | Fondation Centre National De Transfusion Sanguine | Milieu de culture comportant de l'albumine humaine, procédé de préparation d'un produit injectable à partir de ce milieu, produit obtenu et son utilisation, composition obtenue |
EP0255420A2 (fr) * | 1986-07-26 | 1988-02-03 | Minophagen Pharmaceutical Company | Agent antiviral d'inhibition de la croissance du virus du syndrome immuno-deficitaire acquis (SIDA) |
DE3733181C1 (de) * | 1987-10-01 | 1989-01-19 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines hochreinen,virussicheren,biologisch aktiven Transferrinpraeparates |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 106, No. 13, 15 March 1987, (Columbus, Ohio, US), D.J. DARGAN et al.: "The Antiviral Activity against Herpes Simplex Virus of the Triterpenoid Compounds Carbenoxolone Sodium and Cicloxolone Sodium", see page 26 *Abstract 95655m & J. Antimicrob. Chemother. 1986, 1, (Suppl. B), 185-200* * |
Also Published As
Publication number | Publication date |
---|---|
AU4525089A (en) | 1990-06-12 |
AU4664989A (en) | 1990-06-12 |
AU4653989A (en) | 1990-06-12 |
EP0406369A1 (fr) | 1991-01-09 |
EP0399027A1 (fr) | 1990-11-28 |
WO1990005546A1 (fr) | 1990-05-31 |
AU4750390A (en) | 1990-06-12 |
US5128149A (en) | 1992-07-07 |
AU4525289A (en) | 1990-06-12 |
US4891221A (en) | 1990-01-02 |
WO1990005550A1 (fr) | 1990-05-31 |
JPH03503170A (ja) | 1991-07-18 |
WO1990005547A1 (fr) | 1990-05-31 |
JPH03503287A (ja) | 1991-07-25 |
US5128150A (en) | 1992-07-07 |
AU4636589A (en) | 1990-06-12 |
WO1990005533A1 (fr) | 1990-05-31 |
WO1990005548A1 (fr) | 1990-05-31 |
WO1990005520A2 (fr) | 1990-05-31 |
US4933169A (en) | 1990-06-12 |
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