TN2013000179A1 - Piperidinone carboxamide azaindane cgrp receptor antagonists - Google Patents
Piperidinone carboxamide azaindane cgrp receptor antagonistsInfo
- Publication number
- TN2013000179A1 TN2013000179A1 TNP2013000179A TN2013000179A TN2013000179A1 TN 2013000179 A1 TN2013000179 A1 TN 2013000179A1 TN P2013000179 A TNP2013000179 A TN P2013000179A TN 2013000179 A TN2013000179 A TN 2013000179A TN 2013000179 A1 TN2013000179 A1 TN 2013000179A1
- Authority
- TN
- Tunisia
- Prior art keywords
- receptor antagonists
- cgrp receptor
- piperidinone carboxamide
- carboxamide azaindane
- piperidinone
- Prior art date
Links
- 108010078311 Calcitonin Gene-Related Peptide Receptors Proteins 0.000 title abstract 2
- 102000008323 calcitonin gene-related peptide receptor activity proteins Human genes 0.000 title 1
- 150000003857 carboxamides Chemical class 0.000 title 1
- LPAGFVYQRIESJQ-UHFFFAOYSA-N indoline Chemical compound C1=CC=C2NCCC2=C1 LPAGFVYQRIESJQ-UHFFFAOYSA-N 0.000 title 1
- XUWHAWMETYGRKB-UHFFFAOYSA-N piperidin-2-one Chemical compound O=C1CCCCN1 XUWHAWMETYGRKB-UHFFFAOYSA-N 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 108090000932 Calcitonin Gene-Related Peptide Proteins 0.000 abstract 2
- 102100025588 Calcitonin gene-related peptide 1 Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000014468 Calcitonin Gene-Related Peptide Receptors Human genes 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- -1 piperidinone carboxamide azaindane derivatives Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention is directed to piperidinone carboxamide azaindane derivatives of formula I which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/060081 WO2012064910A1 (en) | 2010-11-12 | 2011-11-10 | Piperidinone carboxamide azaindane cgrp receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2013000179A1 true TN2013000179A1 (en) | 2014-11-10 |
Family
ID=54360614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2013000179A TN2013000179A1 (en) | 2011-11-10 | 2013-04-24 | Piperidinone carboxamide azaindane cgrp receptor antagonists |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2013000179A1 (en) |
-
2013
- 2013-04-24 TN TNP2013000179A patent/TN2013000179A1/en unknown
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