PL2833907T3 - Kompozycje i sposoby hamowania masp-1 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii - Google Patents

Kompozycje i sposoby hamowania masp-1 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii

Info

Publication number: PL2833907T3
Authority: PL; Poland
Prior art keywords: masp; inhibting; compositions; treatment; methods
Prior art date: 2012-04-06

Application number

PL13798222T

Other languages

English (en)

Inventor

Hans-Wilhelm Schwaeble

Gregory A. Demopulos

Original Assignee

Omeros Corporation

University Of Leicester

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-04-06

Filing date

2013-04-05

Publication date

2018-08-31

2013-04-05 Application filed by Omeros Corporation, University Of Leicester filed Critical Omeros Corporation

2018-08-31 Publication of PL2833907T3 publication Critical patent/PL2833907T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Hematology (AREA)
Diabetes (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Mechanical Treatment Of Semiconductor (AREA)
Medicinal Preparation (AREA)

PL13798222T 2012-04-06 2013-04-05 Kompozycje i sposoby hamowania masp-1 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii PL2833907T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201261621461P	2012-04-06	2012-04-06
PCT/US2013/035488 WO2013180834A2 (en)	2012-04-06	2013-04-05	Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria
EP13798222.9A EP2833907B1 (en)	2012-04-06	2013-04-05	Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria

Publications (1)

Publication Number	Publication Date
PL2833907T3 true PL2833907T3 (pl)	2018-08-31

Family

ID=49325295

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL13798222T PL2833907T3 (pl)	2012-04-06	2013-04-05	Kompozycje i sposoby hamowania masp-1 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii
PL18158799T PL3366307T3 (pl)	2012-04-06	2013-04-05	Kompozycje i sposoby hamowania masp-1 i/lub masp-2 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL18158799T PL3366307T3 (pl)	2012-04-06	2013-04-05	Kompozycje i sposoby hamowania masp-1 i/lub masp-2 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii

Country Status (29)

Country	Link
US (3)	US20130273053A1 (pl)
EP (2)	EP2833907B1 (pl)
JP (3)	JP6366571B2 (pl)
KR (2)	KR102318623B1 (pl)
CN (1)	CN104661676A (pl)
AU (3)	AU2013267909B2 (pl)
BR (1)	BR112014024793A2 (pl)
CA (2)	CA3087933A1 (pl)
CL (1)	CL2014002694A1 (pl)
CY (1)	CY1120736T1 (pl)
DK (2)	DK2833907T3 (pl)
ES (2)	ES2894944T3 (pl)
HR (1)	HRP20180671T1 (pl)
HU (1)	HUE036930T2 (pl)
IL (2)	IL234991B (pl)
IN (1)	IN2014KN02324A (pl)
LT (1)	LT2833907T (pl)
MX (2)	MX388278B (pl)
NO (1)	NO2881536T3 (pl)
NZ (2)	NZ781091A (pl)
PL (2)	PL2833907T3 (pl)
PT (1)	PT2833907T (pl)
RS (1)	RS57266B1 (pl)
RU (2)	RU2655299C2 (pl)
SI (1)	SI2833907T1 (pl)
SM (1)	SMT201800253T1 (pl)
TR (1)	TR201806939T4 (pl)
WO (1)	WO2013180834A2 (pl)
ZA (1)	ZA201408100B (pl)

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CN118924900A (zh) *	2012-06-18	2024-11-12	奥默罗斯公司	抑制masp-1和/或masp-2和/或masp-3的组合物和方法
CA2906096C (en)	2013-03-15	2022-03-15	Omeros Corporation	Methods of generating bioactive peptide-bearing antibodies and compositions comprising the same
US20140363433A1 (en)	2013-03-15	2014-12-11	Omeros Corporation	Methods of Generating Bioactive Peptide-bearing Antibodies and Compositions Comprising the Same
JOP20170154B1 (ar) *	2016-08-01	2023-03-28	Omeros Corp	تركيبات وطرق لتثبيط masp-3 لعلاج أمراض واضطرابات مختلفة
CN110214151A (zh)	2016-11-28	2019-09-06	中外制药株式会社	具有可调节的配体结合活性的配体结合分子
KR102630923B1 (ko) *	2016-11-28	2024-01-30	추가이 세이야쿠 가부시키가이샤	항원 결합 도메인 및 운반 부분을 포함하는 폴리펩티드
WO2018186322A1 (en) *	2017-04-03	2018-10-11	Chugai Seiyaku Kabushiki Kaisha	Anti-masp-1 antibodies and methods of use
CA3083259A1 (en)	2017-11-28	2019-06-06	Chugai Seiyaku Kabushiki Kaisha	Polypeptide including antigen-binding domain and carrying section
KR20200089312A (ko)	2017-11-28	2020-07-24	추가이 세이야쿠 가부시키가이샤	리간드 결합 활성을 조정 가능한 리간드 결합 분자
IL311042A (en) *	2018-05-29	2024-04-01	Omeros Corp	MASP-2 inhibitors and methods of use
US12077577B2 (en)	2018-05-30	2024-09-03	Chugai Seiyaku Kabushiki Kaisha	Polypeptide comprising aggrecan binding domain and carrying moiety
JOP20220011A1 (ar) *	2019-07-31	2023-01-30	Biocryst Pharm Inc	نظم جرعات لمثبطات عامل متمم d عن طريق الفم
IL293588A (en)	2019-12-04	2022-08-01	Omeros Corp	Masp-2 inhibitor compounds, compositions comprising same and uses thereof
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WO2024251199A1 (zh) *	2023-06-09	2024-12-12	舒泰神（北京）生物制药股份有限公司	特异性结合masp3的抗体以及特异性结合masp3和masp2的多特异性抗体

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2013
- 2013-04-05 PL PL13798222T patent/PL2833907T3/pl unknown
- 2013-04-05 BR BR112014024793A patent/BR112014024793A2/pt not_active Application Discontinuation
- 2013-04-05 MX MX2018008658A patent/MX388278B/es unknown
- 2013-04-05 NZ NZ781091A patent/NZ781091A/en unknown
- 2013-04-05 AU AU2013267909A patent/AU2013267909B2/en active Active
- 2013-04-05 RS RS20180586A patent/RS57266B1/sr unknown
- 2013-04-05 SI SI201331032T patent/SI2833907T1/en unknown
- 2013-04-05 US US13/857,391 patent/US20130273053A1/en not_active Abandoned
- 2013-04-05 HR HRP20180671TT patent/HRP20180671T1/hr unknown
- 2013-04-05 HU HUE13798222A patent/HUE036930T2/hu unknown
- 2013-04-05 EP EP13798222.9A patent/EP2833907B1/en active Active
- 2013-04-05 ES ES18158799T patent/ES2894944T3/es active Active
- 2013-04-05 RU RU2014144621A patent/RU2655299C2/ru active
- 2013-04-05 MX MX2014012045A patent/MX357540B/es active IP Right Grant
- 2013-04-05 CA CA3087933A patent/CA3087933A1/en active Pending
- 2013-04-05 LT LTEP13798222.9T patent/LT2833907T/lt unknown
- 2013-04-05 DK DK13798222.9T patent/DK2833907T3/en active
- 2013-04-05 KR KR1020207022397A patent/KR102318623B1/ko active Active
- 2013-04-05 PL PL18158799T patent/PL3366307T3/pl unknown
- 2013-04-05 KR KR1020147030787A patent/KR102142508B1/ko active Active
- 2013-04-05 EP EP18158799.9A patent/EP3366307B1/en active Active
- 2013-04-05 CA CA2869326A patent/CA2869326C/en active Active
- 2013-04-05 WO PCT/US2013/035488 patent/WO2013180834A2/en active Application Filing
- 2013-04-05 RU RU2018114903A patent/RU2018114903A/ru unknown
- 2013-04-05 IN IN2324KON2014 patent/IN2014KN02324A/en unknown
- 2013-04-05 DK DK18158799.9T patent/DK3366307T3/da active
- 2013-04-05 NZ NZ629675A patent/NZ629675A/en unknown
- 2013-04-05 SM SM20180253T patent/SMT201800253T1/it unknown
- 2013-04-05 TR TR2018/06939T patent/TR201806939T4/tr unknown
- 2013-04-05 CN CN201380029994.3A patent/CN104661676A/zh active Pending
- 2013-04-05 JP JP2015504751A patent/JP6366571B2/ja active Active
- 2013-04-05 ES ES13798222.9T patent/ES2670668T3/es active Active
- 2013-04-05 PT PT137982229T patent/PT2833907T/pt unknown
2014
- 2014-10-05 IL IL234991A patent/IL234991B/en active IP Right Grant
- 2014-10-06 CL CL2014002694A patent/CL2014002694A1/es unknown
- 2014-11-05 ZA ZA2014/08100A patent/ZA201408100B/en unknown
- 2014-12-04 NO NO14196403A patent/NO2881536T3/no unknown
2018
- 2018-01-31 AU AU2018200721A patent/AU2018200721B2/en active Active
- 2018-05-23 CY CY181100540T patent/CY1120736T1/el unknown
- 2018-07-03 JP JP2018126460A patent/JP6815355B2/ja active Active
2019
- 2019-02-26 US US16/285,741 patent/US20190382505A1/en not_active Abandoned
2020
- 2020-05-17 IL IL274721A patent/IL274721B/en unknown
- 2020-06-22 AU AU2020204163A patent/AU2020204163A1/en not_active Abandoned
- 2020-09-17 JP JP2020156216A patent/JP2021001199A/ja active Pending
2021
- 2021-10-11 US US17/498,521 patent/US20220242972A1/en active Pending

Also Published As

Publication number	Publication date
AU2013267909B2 (en)	2018-03-01
WO2013180834A2 (en)	2013-12-05
IN2014KN02324A (pl)	2015-05-01
JP2015514117A (ja)	2015-05-18
HUE036930T2 (hu)	2018-08-28
AU2018200721B2 (en)	2020-03-26
AU2018200721A1 (en)	2018-02-22
KR20200097808A (ko)	2020-08-19
IL234991A0 (en)	2014-12-31
EP2833907A2 (en)	2015-02-11
CL2014002694A1 (es)	2015-08-28
NZ727063A (en)	2021-10-29
MX2014012045A (es)	2015-05-15
TR201806939T4 (tr)	2018-06-21
KR102142508B1 (ko)	2020-08-10
CA2869326C (en)	2021-09-21
MX357540B (es)	2018-07-13
SMT201800253T1 (it)	2018-07-17
MX388278B (es)	2025-03-18
RU2014144621A (ru)	2016-05-27
EP3366307A1 (en)	2018-08-29
JP6366571B2 (ja)	2018-08-01
NO2881536T3 (pl)	2018-06-30
PL3366307T3 (pl)	2022-03-07
WO2013180834A3 (en)	2014-04-03
EP2833907B1 (en)	2018-02-28
JP6815355B2 (ja)	2021-01-20
MX2018008658A (es)	2021-10-19
US20220242972A1 (en)	2022-08-04
RS57266B1 (sr)	2018-08-31
DK2833907T3 (en)	2018-05-28
AU2013267909A1 (en)	2014-11-27
KR102318623B1 (ko)	2021-11-02
IL274721A (en)	2020-07-30
NZ629675A (en)	2017-02-24
EP2833907A4 (en)	2016-03-16
EP3366307B1 (en)	2021-07-28
PT2833907T (pt)	2018-05-29
BR112014024793A2 (pt)	2019-08-27
CN104661676A (zh)	2015-05-27
LT2833907T (lt)	2018-06-11
KR20150003785A (ko)	2015-01-09
IL274721B (en)	2022-04-01
ES2670668T3 (es)	2018-05-31
SI2833907T1 (en)	2018-07-31
JP2021001199A (ja)	2021-01-07
HRP20180671T1 (hr)	2018-07-13
NZ781091A (en)	2022-04-29
HK1206996A1 (en)	2016-01-22
IL234991B (en)	2020-06-30
ZA201408100B (en)	2022-05-25
CA2869326A1 (en)	2013-12-05
CY1120736T1 (el)	2019-12-11
CA3087933A1 (en)	2013-12-05
ES2894944T3 (es)	2022-02-16
US20190382505A1 (en)	2019-12-19
RU2018114903A3 (pl)	2021-08-12
JP2018162307A (ja)	2018-10-18
DK3366307T3 (da)	2021-11-01
RU2018114903A (ru)	2019-03-04
RU2655299C2 (ru)	2018-05-24
AU2020204163A1 (en)	2020-07-09
US20130273053A1 (en)	2013-10-17

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PL2833907T3 (pl)	2018-08-31	Kompozycje i sposoby hamowania masp-1 i/lub masp-3 do leczenia napadowej nocnej hemoglobinurii
IL266582A (en)	2019-07-31	Preparations and methods for the treatment of hemoglobin diseases
HUE041553T2 (hu)	2019-05-28	Lizoszomális tárolási betegségek (LSD) kezelése és génterápia
EP2831001A4 (en)	2016-04-27	COMPOSITION FOR THE TREATMENT OF WATER AND METHOD FOR USE
SG11201601412XA (en)	2016-03-30	Compositions and methods for the treatment of presbyopia
IL238177A0 (en)	2015-05-31	Methods and preparations for the treatment of cancer
IL242483B (en)	2020-03-31	Preparations containing omomyc and their use for cancer treatment
EP2817018A4 (en)	2015-09-23	METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
ZA201408056B (en)	2016-04-28	Compositions and methods for the treatment of mucositis
ZA201408055B (en)	2016-03-30	Compositions and methods for the treatment of local pain
IL225793A0 (en)	2013-09-30	Methods and preparations for curing insulin-related medical conditions
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IL238126B (en)	2019-07-31	Compositions for the treatment and prevention of obesity
ZA201503844B (en)	2017-11-29	Compositions and methods for treating dental caries
IL238602A0 (en)	2015-06-30	Preparations and methods for the treatment of ectodermal dysplasia
IL235812A0 (en)	2015-01-29	Preparations and methods for increasing the effectiveness of bactericidal contraceptives
EP2934501A4 (en)	2016-06-01	USES AND METHOD FOR THE TREATMENT OF LIVER DISEASES OR DRESSES
ZA201408058B (en)	2016-03-30	Compositions and methods for the treatment of epilepsy
ZA201408065B (en)	2016-04-28	Compositions and methods for the treatment of diabetes
PL3079684T3 (pl)	2020-06-01	Kompozycje i sposoby do leczenia chorób związanych z układem renina-angiotensyna
PL2862576T3 (pl)	2017-06-30	Drobnoustroje i zawierające je kompozycje do stosowania do leczenia lub profilaktyki zapalenia sutka
SG11201500838UA (en)	2015-03-30	Eprotirome for use in the prevention and/or treatment of hair disorders and compositions thereof