EP1265634A4 - Procede et composition pour traiter une hyperreactivite bronchique - Google Patents
Procede et composition pour traiter une hyperreactivite bronchiqueInfo
- Publication number
- EP1265634A4 EP1265634A4 EP01918368A EP01918368A EP1265634A4 EP 1265634 A4 EP1265634 A4 EP 1265634A4 EP 01918368 A EP01918368 A EP 01918368A EP 01918368 A EP01918368 A EP 01918368A EP 1265634 A4 EP1265634 A4 EP 1265634A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- airway hyperresponsiveness
- treating airway
- treating
- hyperresponsiveness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000002200 Respiratory Hypersensitivity Diseases 0.000 title 1
- 230000010085 airway hyperresponsiveness Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52504300A | 2000-03-14 | 2000-03-14 | |
US525043 | 2000-03-14 | ||
PCT/US2001/007069 WO2001068130A1 (fr) | 2000-03-14 | 2001-03-06 | Procede et composition pour traiter une hyperreactivite bronchique |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1265634A1 EP1265634A1 (fr) | 2002-12-18 |
EP1265634A4 true EP1265634A4 (fr) | 2005-12-28 |
Family
ID=24091672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01918368A Withdrawn EP1265634A4 (fr) | 2000-03-14 | 2001-03-06 | Procede et composition pour traiter une hyperreactivite bronchique |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1265634A4 (fr) |
AU (2) | AU4545301A (fr) |
CA (1) | CA2403196A1 (fr) |
WO (1) | WO2001068130A1 (fr) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997031532A1 (fr) * | 1996-02-28 | 1997-09-04 | University Of Medicine & Dentistry Of New Jersey | Interleukine-10 anti-sens et procedes d'utilisation |
WO1998010787A2 (fr) * | 1996-09-11 | 1998-03-19 | Prendergast Patrick T | Therapie a but immunitaire |
US5843697A (en) * | 1996-07-17 | 1998-12-01 | University Of Medicine And Dentistry Of New Jersey | Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein |
WO1999027937A2 (fr) * | 1997-11-26 | 1999-06-10 | Previsan Ag | Procede d'inhibition de la production cellulaire de cytokines |
WO2000071140A2 (fr) * | 1999-05-21 | 2000-11-30 | Foodscience Corporation | Procedes et compositions de modulation de la reponse immunitaire et de traitement des maladies inflammatoires |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5833976A (en) * | 1991-08-06 | 1998-11-10 | Schering Corporation | Use of interleukin-10 (IL-10) to treat endotoxin- or superantigen-induced toxicity |
US5959085A (en) * | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
WO1997026278A1 (fr) * | 1996-01-18 | 1997-07-24 | Steeno Research Group A/S | Analogues synthetiques d'il-10 |
-
2001
- 2001-03-06 WO PCT/US2001/007069 patent/WO2001068130A1/fr active IP Right Grant
- 2001-03-06 AU AU4545301A patent/AU4545301A/xx active Pending
- 2001-03-06 CA CA002403196A patent/CA2403196A1/fr not_active Abandoned
- 2001-03-06 AU AU2001245453A patent/AU2001245453B2/en not_active Ceased
- 2001-03-06 EP EP01918368A patent/EP1265634A4/fr not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997031532A1 (fr) * | 1996-02-28 | 1997-09-04 | University Of Medicine & Dentistry Of New Jersey | Interleukine-10 anti-sens et procedes d'utilisation |
US5843697A (en) * | 1996-07-17 | 1998-12-01 | University Of Medicine And Dentistry Of New Jersey | Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein |
WO1998010787A2 (fr) * | 1996-09-11 | 1998-03-19 | Prendergast Patrick T | Therapie a but immunitaire |
WO1999027937A2 (fr) * | 1997-11-26 | 1999-06-10 | Previsan Ag | Procede d'inhibition de la production cellulaire de cytokines |
WO2000071140A2 (fr) * | 1999-05-21 | 2000-11-30 | Foodscience Corporation | Procedes et compositions de modulation de la reponse immunitaire et de traitement des maladies inflammatoires |
Non-Patent Citations (6)
Title |
---|
ARIMA H ET AL: "DESIGN OF POTENT PHOSPHOROTHIOATE ANTISENSE OLIGONUCLEOTIDES DIRECTED TO HUMAN INTERLEUKIN 10 GENE PRODUCT AND THEIR EVALUATION OF ANTISENSE ACTIVITY IN U937 CELLS", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 16, no. 8, August 1999 (1999-08-01), pages 1163 - 1171, XP001053078, ISSN: 0724-8741 * |
ARIMA H ET AL: "SPECIFIC INHIBITION OF INTERLEUKIN-10 PRODUCTION IN MURINE MACROPHAGE-LIKE CELLS BY PHOSPHOROTHIOATE ANTISENSE OLIGONUCLEOTIDES", ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, MARY ANN LIEBERT, INC., NEW YORK, US, vol. 8, August 1998 (1998-08-01), pages 319 - 327, XP002926349, ISSN: 1087-2906 * |
GREENBERGER MARC J ET AL: "Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia.", JOURNAL OF IMMUNOLOGY, vol. 155, no. 2, 1995, pages 722 - 729, XP002236220, ISSN: 0022-1767 * |
KONZO K R ET AL: "Inhibition of interleukin-10 (IL-10) production by fluticasone (Flu).", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 95, no. 1 PART 2, 1995, Fifty-first Annual Meeting of the American Academy of Allergy and Immunology;New York, New York, USA; February 24-March 1, 1995, pages 300, XP008015571, ISSN: 0091-6749 * |
LU L J ET AL: "Inhibition of interleukin-10 (IL-10) production by interleukin-8 (IL-8).", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 95, no. 1 PART 2, 1995, Fifty-first Annual Meeting of the American Academy of Allergy and Immunology;New York, New York, USA; February 24-March 1, 1995, pages 345, XP008015572, ISSN: 0091-6749 * |
See also references of WO0168130A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU4545301A (en) | 2001-09-24 |
EP1265634A1 (fr) | 2002-12-18 |
AU2001245453B2 (en) | 2005-08-25 |
CA2403196A1 (fr) | 2001-09-20 |
WO2001068130A1 (fr) | 2001-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20021007 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 38/20 B Ipc: 7A 61K 39/395 A Ipc: 7C 07K 16/00 B Ipc: 7C 12P 19/34 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20051115 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080916 |