DZ3368A1 - Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide - Google Patents

Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide

Info

Publication number: DZ3368A1
Authority: DZ; Algeria
Prior art keywords: hexane; affinity; opioid receptor; azabicyclo derivatives; azabicyclo
Prior art date: 2000-06-23

Application number

DZ013368A

Other languages

English (en)

Inventor

Bernard Joseph Banks

Douglas James Critcher

Ashley Edward Fenwick

David Morris Gethin

Stephen Paul Gibson

Graham Lunn

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-23

Filing date

2001-06-07

Publication date

2001-12-27

2001-06-07 Application filed by Pfizer filed Critical Pfizer

2001-12-27 Application granted granted Critical

2001-12-27 Publication of DZ3368A1 publication Critical patent/DZ3368A1/fr

Links

VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 title 3
102000003840 Opioid Receptors Human genes 0.000 title 1
108090000137 Opioid Receptors Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Addiction (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Nutrition Science (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DZ013368A 2000-06-23 2001-06-07 Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide DZ3368A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0015562.2A GB0015562D0 (en)	2000-06-23	2000-06-23	Heterocycles
PCT/IB2001/001035 WO2001098267A1 (fr)	2000-06-23	2001-06-07	Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide

Publications (1)

Publication Number	Publication Date
DZ3368A1 true DZ3368A1 (fr)	2001-12-27

Family

ID=9894368

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ013368A DZ3368A1 (fr)	2000-06-23	2001-06-07	Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide

Country Status (34)

Country	Link
EP (1)	EP1292574A1 (fr)
JP (1)	JP2004512263A (fr)
KR (1)	KR20040002386A (fr)
CN (1)	CN1639121A (fr)
AP (1)	AP2002002698A0 (fr)
AR (1)	AR028969A1 (fr)
AU (1)	AU781837B2 (fr)
BG (1)	BG107329A (fr)
BR (1)	BR0111867A (fr)
CA (1)	CA2412188A1 (fr)
CZ (1)	CZ20023967A3 (fr)
DO (1)	DOP2001000187A (fr)
DZ (1)	DZ3368A1 (fr)
EA (1)	EA005117B1 (fr)
GB (1)	GB0015562D0 (fr)
HR (1)	HRP20020998A2 (fr)
HU (1)	HUP0301228A3 (fr)
IL (1)	IL153427A0 (fr)
IS (1)	IS6637A (fr)
MA (1)	MA26915A1 (fr)
MX (1)	MXPA02012878A (fr)
NO (1)	NO20026168L (fr)
NZ (1)	NZ523141A (fr)
OA (1)	OA12293A (fr)
PA (1)	PA8519401A1 (fr)
PE (1)	PE20020253A1 (fr)
PL (1)	PL365956A1 (fr)
SK (1)	SK17172002A3 (fr)
TN (1)	TNSN01094A1 (fr)
UA (1)	UA73176C2 (fr)
UY (1)	UY26787A1 (fr)
WO (1)	WO2001098267A1 (fr)
YU (1)	YU91802A (fr)
ZA (1)	ZA200210278B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ531807A (en) *	2001-10-22	2006-03-31	Pfizer Prod Inc	3-Azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists
RU2336871C2 (ru) *	2002-05-17	2008-10-27	Тиога Фармасьютиклз, Инк.	Применение соединений, которые являются эффективными как селективные модуляторы опиатного рецептора
DE10259245A1 (de)	2002-12-17	2004-07-01	Merck Patent Gmbh	Derivate des Asimadolins mit kovalent gebundenen Säuren
SI2070922T1 (sl)	2004-02-23	2011-12-30	Glaxo Group Ltd	Derivati azabiciklo(3.1.0) heksana, uporabni kot modulatorji dopaminskih receptorjev d3
GB0507680D0 (en) *	2005-04-15	2005-05-25	Glaxo Group Ltd	Compounds
DE602006017543D1 (de) *	2005-06-14	2010-11-25	Glaxo Group Ltd	Neue verbindungen
DE602007012531D1 (de)	2006-04-03	2011-03-31	Glaxo Group Ltd	Azabicycloä3.1.0ühexanderivate als modulatoren von dopamin-d3-rezeptoren
EP2136801B1 (fr)	2007-03-30	2012-08-29	Tioga Pharmaceuticals, Inc.	Agonistes du récepteur opiacé kappa pour le traitement du syndrome du côlon irritable avec alternance ou à diarrhée prédominante
TWI423801B (zh) *	2007-08-27	2014-01-21	Theravance Inc	作為μ類鴉片受體拮抗劑之８－氮雜雙環〔３．２．１〕辛基－２－羥基苯甲醯胺化合物
WO2011154827A2 (fr)	2010-06-11	2011-12-15	Rhodes Technologies	Procédés catalysés par métal de transition pour la préparation de composés de n-allyle et utilisation de ceux-ci
WO2012042539A2 (fr)	2010-09-28	2012-04-05	Panacea Biotec Ltd	Nouveaux composés bicycliques
AU2014354085B2 (en) *	2013-11-20	2018-04-26	Ube Corporation	Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes
JP6087035B1 (ja)	2015-05-20	2017-03-01	株式会社三和化学研究所	新規３−アザビシクロ［３．１．０］ヘキサン誘導体の塩の結晶及びその医薬用途
CA3052479A1 (fr)	2017-02-17	2018-08-23	Trevena, Inc.	Composes modulateurs du recepteur des opioides delta contenant des heterocycles aza a 7 chainons, et leurs procedes de preparation et d'utilisation
US11702408B2 (en)	2017-02-17	2023-07-18	Trevena, Inc.	5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
US20200237720A1 (en)	2017-03-02	2020-07-30	Sanwa Kagaku Kenkyusho Co., Ltd.	Therapeutic agent for alcohol use disorders
CN108250088B (zh) *	2018-01-04	2020-10-30	四川之江高新材料股份有限公司	N，n，n′-三甲基-n′-羟乙基双氨基乙基醚的制备方法
CN115825305B (zh) *	2022-10-21	2024-09-20	昆明理工大学	一种分子印迹固相微萃取纤维及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3065230A (en) *	1959-03-16	1962-11-20	Burroughs Wellcome Co	Azabicyclohexanes and method of preparing them
ATE110057T1 (de) *	1987-04-16	1994-09-15	Lilly Co Eli	Piperidine als opioid-antagoniste.
US5159081A (en) *	1991-03-29	1992-10-27	Eli Lilly And Company	Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
DE4341403A1 (de) *	1993-12-04	1995-06-08	Basf Ag	N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
TWI244481B (en) *	1998-12-23	2005-12-01	Pfizer	3-azabicyclo[3.1.0]hexane derivatives useful in therapy
PE20001420A1 (es) *	1998-12-23	2000-12-18	Pfizer	Moduladores de ccr5

2000
- 2000-06-23 GB GBGB0015562.2A patent/GB0015562D0/en not_active Ceased
2001
- 2001-06-06 DO DO2001000187A patent/DOP2001000187A/es unknown
- 2001-06-07 IL IL15342701A patent/IL153427A0/xx unknown
- 2001-06-07 OA OA1200200386A patent/OA12293A/en unknown
- 2001-06-07 PL PL01365956A patent/PL365956A1/xx not_active Application Discontinuation
- 2001-06-07 CZ CZ20023967A patent/CZ20023967A3/cs unknown
- 2001-06-07 MX MXPA02012878A patent/MXPA02012878A/es unknown
- 2001-06-07 SK SK1717-2002A patent/SK17172002A3/sk unknown
- 2001-06-07 JP JP2002504223A patent/JP2004512263A/ja not_active Withdrawn
- 2001-06-07 CA CA002412188A patent/CA2412188A1/fr not_active Abandoned
- 2001-06-07 EA EA200201269A patent/EA005117B1/ru not_active IP Right Cessation
- 2001-06-07 WO PCT/IB2001/001035 patent/WO2001098267A1/fr not_active Application Discontinuation
- 2001-06-07 KR KR1020027017503A patent/KR20040002386A/ko not_active Ceased
- 2001-06-07 NZ NZ523141A patent/NZ523141A/en unknown
- 2001-06-07 BR BR0111867-6A patent/BR0111867A/pt not_active IP Right Cessation
- 2001-06-07 AP APAP/P/2002/002698A patent/AP2002002698A0/en unknown
- 2001-06-07 AU AU62591/01A patent/AU781837B2/en not_active Ceased
- 2001-06-07 EP EP01936728A patent/EP1292574A1/fr not_active Withdrawn
- 2001-06-07 YU YU91802A patent/YU91802A/sh unknown
- 2001-06-07 HU HU0301228A patent/HUP0301228A3/hu unknown
- 2001-06-07 DZ DZ013368A patent/DZ3368A1/fr active
- 2001-06-07 CN CNA018116086A patent/CN1639121A/zh active Pending
- 2001-06-12 PA PA20018519401A patent/PA8519401A1/es unknown
- 2001-06-21 UY UY26787A patent/UY26787A1/es not_active Application Discontinuation
- 2001-06-21 PE PE2001000604A patent/PE20020253A1/es not_active Application Discontinuation
- 2001-06-21 AR ARP010102957A patent/AR028969A1/es unknown
- 2001-06-22 TN TNTNSN01094A patent/TNSN01094A1/fr unknown
- 2001-07-06 UA UA20021210406A patent/UA73176C2/uk unknown
2002
- 2002-11-28 IS IS6637A patent/IS6637A/is unknown
- 2002-11-28 BG BG107329A patent/BG107329A/xx unknown
- 2002-12-12 HR HR20020998A patent/HRP20020998A2/hr not_active Application Discontinuation
- 2002-12-16 MA MA26955A patent/MA26915A1/fr unknown
- 2002-12-19 ZA ZA200210278A patent/ZA200210278B/xx unknown
- 2002-12-20 NO NO20026168A patent/NO20026168L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1292574A1 (fr)	2003-03-19
WO2001098267A1 (fr)	2001-12-27
BR0111867A (pt)	2003-07-01
AP2002002698A0 (en)	2002-12-31
SK17172002A3 (sk)	2004-09-08
EA200201269A1 (ru)	2003-06-26
CN1639121A (zh)	2005-07-13
JP2004512263A (ja)	2004-04-22
PA8519401A1 (es)	2002-12-30
NO20026168D0 (no)	2002-12-20
CZ20023967A3 (cs)	2004-02-18
UY26787A1 (es)	2002-01-31
AU6259101A (en)	2002-01-02
WO2001098267A8 (fr)	2003-02-27
NO20026168L (no)	2003-02-18
DOP2001000187A (es)	2002-03-30
OA12293A (en)	2004-03-18
MXPA02012878A (es)	2003-05-14
AU781837B2 (en)	2005-06-16
ZA200210278B (en)	2003-12-19
BG107329A (en)	2003-07-31
PL365956A1 (en)	2005-01-24
HRP20020998A2 (en)	2004-02-29
EA005117B1 (ru)	2004-10-28
HUP0301228A3 (en)	2005-08-29
PE20020253A1 (es)	2002-04-08
IS6637A (is)	2002-11-28
GB0015562D0 (en)	2000-08-16
NZ523141A (en)	2005-06-24
KR20040002386A (ko)	2004-01-07
AR028969A1 (es)	2003-05-28
UA73176C2 (en)	2005-06-15
IL153427A0 (en)	2003-07-06
MA26915A1 (fr)	2004-12-20
YU91802A (sh)	2006-05-25
TNSN01094A1 (fr)	2005-11-10
CA2412188A1 (fr)	2001-12-27
HUP0301228A2 (hu)	2003-08-28

Publication	Publication Date	Title
DZ3368A1 (fr)	2001-12-27	Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide
ATE335725T1 (de)	2006-09-15	3-azabicyclo(3.1.0)hexanderivate als opiat rezeptoren liganden
MA27032A1 (fr)	2004-12-20	Nouveaux derives de l'indole a affinite pour le recepteur 5-ht6
IS7187A (is)	2004-03-18	3-asabísýkló (3.1.0) hexanafleiður sem ópíóíðviðtaka mótlyf
ATE354570T1 (de)	2007-03-15	5,6-diaryl-pyrazineamidderivate als cb1 antagonisten
MA26831A1 (fr)	2004-12-20	Derives de benzodiazepine."
ZA991413B (en)	1999-08-30	Substituted quinoxaline derivatives as interleukin-8 receptor antagonists.
EE200100145A (et)	2002-06-17	Opioidiretseptoriga koos toimivad 4,4-biarüülpiperidiini derivaadid
CY2010003I1 (el)	2012-01-25	Αγωνιστες των βητα-2 αδρενεργικων υποδοχεων
MXPA03002907A (es)	2003-06-24	Antagonistas receptores metabotropicos de glutamato.
MA26932A1 (fr)	2004-12-20	Derives d'imidazole.
MXPA03005743A (es)	2003-09-05	Antagonistas muscarinicos.
MXPA03006991A (es)	2003-11-18	Derivados de piperidina como antagonistas de neurocinina 1.
HK1042699A1 (en)	2002-08-23	N-triazolylmethyl-piperazine derivatives as neurokinin receptor antagonists.
HK1045684A1 (en)	2002-12-06	Biphenyl derivatives as antagonists of the neurokinine-1 receptor.
MXPA03003892A (es)	2003-07-28	Antagonistas del receptor bombesin.
AU2001259051A1 (en)	2001-11-26	Piperidyindoles as serotonin receptor ligands
MXPA03004414A (es)	2003-09-04	Natagonistas del receptor bombesin.
FR2782251B1 (fr)	2000-10-13	Pietement pour meuble
EP1278538A4 (fr)	2005-05-04	Anticorps se liant a cd18 et inhibant des troubles apparentes a la stenose
SE9800815D0 (sv)	1998-03-13	Bio-chelating agents, high affinity bio-target antagonists
FI4690U1 (fi)	2000-11-15	Istuin
ES1049696Y (es)	2002-05-16	Percha con dispositivo de enganche.
ES1049951Y (es)	2002-06-01	Percha perfeccionada.
IT245505Y1 (it)	2002-03-22	Struttura di zoccolo, particolarmente per l'occultamento dei piedinidi mobili