NO20063675L - Acylaminotiazolderlvater, fremstillingsmater og anvendelse derav I terapeutika - Google Patents

Acylaminotiazolderlvater, fremstillingsmater og anvendelse derav I terapeutika

Info

Publication number: NO20063675L
Authority: NO; Norway
Prior art keywords: optionally substituted; alkyl; alkoxy; cycloalkyl; hydroxy
Prior art date: 2004-01-16

Application number

NO20063675A

Other languages

English (en)

Norwegian (no)

Inventor

Viviane Van Dorsselaer

Sylvie Baltzer

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-16

Filing date

2006-08-15

Publication date

2006-10-16

2004-01-16 Priority claimed from FR0400387A external-priority patent/FR2865206B1/fr

2004-07-22 Priority claimed from FR0408115A external-priority patent/FR2873370B1/fr

2006-08-15 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2006-10-16 Publication of NO20063675L publication Critical patent/NO20063675L/no

Links

239000003814 drug Substances 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000000753 cycloalkyl group Chemical group 0.000 abstract 3
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical compound C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 abstract 2
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
LBUJPTNKIBCYBY-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinoline Chemical group C1=CC=C2CCCNC2=C1 LBUJPTNKIBCYBY-UHFFFAOYSA-N 0.000 abstract 1
NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
HONIICLYMWZJFZ-UHFFFAOYSA-N azetidine Chemical compound C1CNC1 HONIICLYMWZJFZ-UHFFFAOYSA-N 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
229930192474 thiophene Natural products 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20063675A 2004-01-16 2006-08-15 Acylaminotiazolderlvater, fremstillingsmater og anvendelse derav I terapeutika NO20063675L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0400387A FR2865206B1 (fr)	2004-01-16	2004-01-16	Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
FR0408115A FR2873370B1 (fr)	2004-07-22	2004-07-22	Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
PCT/FR2005/000032 WO2005073226A1 (fr)	2004-01-16	2005-01-07	Derives d’acylaminothiazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
NO20063675L true NO20063675L (no)	2006-10-16

Family

ID=34828645

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20063675A NO20063675L (no)	2004-01-16	2006-08-15	Acylaminotiazolderlvater, fremstillingsmater og anvendelse derav I terapeutika

Country Status (15)

Country	Link
US (1)	US7582664B2 (fr)
EP (1)	EP1709041A1 (fr)
JP (1)	JP2007517840A (fr)
AR (1)	AR047387A1 (fr)
AU (1)	AU2005209442B2 (fr)
BR (1)	BRPI0506880A (fr)
CA (1)	CA2551142A1 (fr)
HK (1)	HK1104542A1 (fr)
IL (1)	IL176701A (fr)
MA (1)	MA28233A1 (fr)
NO (1)	NO20063675L (fr)
NZ (1)	NZ548531A (fr)
RU (1)	RU2401262C2 (fr)
TW (1)	TWI340642B (fr)
WO (1)	WO2005073226A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2389062T3 (es) *	2006-01-18	2012-10-22	Amgen, Inc	Compuestos de tiazol como inhibidores de proteína cinasa B (PKB)
EP2173728A2 (fr)	2007-07-17	2010-04-14	Amgen Inc.	Modulateurs hétérocycliques de pkb
AU2008276512A1 (en) *	2007-07-17	2009-01-22	Amgen Inc.	Thiadiazole modulators of PKB

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9401034D0 (en) *	1994-01-20	1994-03-16	British Bio Technology	Metalloproteinase inhibitors
ATE296797T1 (de) *	1996-11-22	2005-06-15	Elan Pharm Inc	N-(aryl/heteroaryl/alkylacetyl) amino saüre amide,pharmazeutische zusammensetzungen damit, und methodenzur inhibierung beta-amyloid peptid freisetzung oder synthese
AU6229699A (en) *	1998-10-26	2000-05-15	Sumitomo Pharmaceuticals Company, Limited	Beta-amyloid formation inhibitors
US6114365A (en) *	1999-08-12	2000-09-05	Pharmacia & Upjohn S.P.A.	Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents
AR039059A1 (es) *	2001-08-06	2005-02-09	Sanofi Aventis	Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios
FR2842523A1 (fr) *	2002-07-17	2004-01-23	Sanofi Synthelabo	Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
CA2501803A1 (fr) *	2002-10-09	2004-04-22	Pfizer Products Inc.	Composes thiazole utiles pour le traitement des maladies neurodegeneratives
DK1709018T3 (da) *	2004-01-16	2011-11-14	Sanofi Sa	Acylaminothiazolderivater og anvendelse deraf som beta-amyloid-hæmmere

2005
- 2005-01-07 NZ NZ548531A patent/NZ548531A/en unknown
- 2005-01-07 EP EP05717380A patent/EP1709041A1/fr not_active Withdrawn
- 2005-01-07 CA CA002551142A patent/CA2551142A1/fr not_active Abandoned
- 2005-01-07 AU AU2005209442A patent/AU2005209442B2/en not_active Ceased
- 2005-01-07 JP JP2006548342A patent/JP2007517840A/ja not_active Ceased
- 2005-01-07 BR BRPI0506880-0A patent/BRPI0506880A/pt not_active IP Right Cessation
- 2005-01-07 WO PCT/FR2005/000032 patent/WO2005073226A1/fr active Application Filing
- 2005-01-07 RU RU2006129642/04A patent/RU2401262C2/ru not_active IP Right Cessation
- 2005-01-14 TW TW094101173A patent/TWI340642B/zh not_active IP Right Cessation
- 2005-01-14 AR ARP050100129A patent/AR047387A1/es unknown
2006
- 2006-06-19 MA MA29119A patent/MA28233A1/fr unknown
- 2006-07-04 IL IL176701A patent/IL176701A/en not_active IP Right Cessation
- 2006-07-07 US US11/456,123 patent/US7582664B2/en not_active Expired - Fee Related
- 2006-08-15 NO NO20063675A patent/NO20063675L/no not_active Application Discontinuation
2007
- 2007-09-06 HK HK07109706.9A patent/HK1104542A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU2005209442B2 (en)	2011-03-31
EP1709041A1 (fr)	2006-10-11
MA28233A1 (fr)	2006-10-02
TW200533345A (en)	2005-10-16
RU2006129642A (ru)	2008-02-27
NZ548531A (en)	2010-01-29
IL176701A0 (en)	2006-10-31
IL176701A (en)	2012-01-31
US7582664B2 (en)	2009-09-01
WO2005073226A1 (fr)	2005-08-11
AR047387A1 (es)	2006-01-18
CA2551142A1 (fr)	2005-08-11
US20060293365A1 (en)	2006-12-28
RU2401262C2 (ru)	2010-10-10
TWI340642B (en)	2011-04-21
AU2005209442A1 (en)	2005-08-11
HK1104542A1 (en)	2008-01-18
JP2007517840A (ja)	2007-07-05
BRPI0506880A (pt)	2007-06-26

Legal Events

Date	Code	Title	Description
2012-08-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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WO2008078196A3 (fr)	2008-11-06	Dérivés de pyridopyrimidone d'hétéroaryle substituée
NO20066015L (no)	2007-02-13	Fuserte heterosykliske forbindelser
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HUP0303801A2 (hu)	2004-03-01	Heterociklusos alkoxi-, alkil-tio- és alkil-amino-benzazol-származékok, mint 5-hidroxi-triptamin-6 ligandumok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
ATE476431T1 (de)	2010-08-15	Piperidin- und azetidinderivate als glyt1- inhibitoren
NO20063675L (no)	2006-10-16	Acylaminotiazolderlvater, fremstillingsmater og anvendelse derav I terapeutika