Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P3/00—Fungicides
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
  • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
  • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
  • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
  • A01N43/647—Triazoles; Hydrogenated triazoles
  • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
  • A01N59/16—Heavy metals; Compounds thereof
  • A01N59/20—Copper
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P11/00—Rodenticides
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P21/00—Plant growth regulators
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P5/00—Nematocides
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
  • A01P7/00—Arthropodicides

Definitions

• Active compound combinations having fungicidal/insecticidal/acaricidal properties
• the present invention relates to active compound combinations comprising firstly the compound of formula (I) as shown below and secondly at least one active compound of group (II) selected from Fungicide Groups (1) to (15).
• active compound combinations comprising firstly the compound of formula (I) as shown below and secondly at least one active compound of group (II) selected from Fungicide Groups (1) to (15).
• Such combinations are highly suitable for controlling animal and microbial pests, such as unwanted insects, arachnids, especially acarids (mites), nematodes as well as for controlling unwanted microorganism and as plant strengthening agents.
• the compound of the formula (I) and methods for its production are known from WO 2020/002082 and its use for controlling animal pests has been described.
• the acaricidal and/or insecticidal efficacy and/or the activity spectrum and/or the compatibility of this compound with plants, especially with respect to crop plants, is not always satisfactory. Therefore, novel active compound combinations with improved properties are in great demand.
• an active compound combination comprising the compound of the formula (I) and at least one active compound of group (II) which is selected from
• Fungicide Groups (1) to (15) is highly suitable for the control of animal and microbial pests as well as for the control of unwanted microorganism and as plant strengthening agents. Especially, such active compound combinations have very good fungicidal, insecticidal, acaricidal and/or nematicidal properties.
• Such active compound combinations are very suitable for controlling animal and microbial pests such as insects and/or arachnids, especially acarids, and/or nematodes, as well as for controlling unwanted microorganism, and indirectly improve plant health. Further, such active compound combinations can be used for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by such pests, e.g. insects, mites and phytopathogens. Further, such active compound combinations are suitable as plant strengthening agents.
• the insecticidal effect and/or arachnicidal/acaricidal effect and/or nematicidal effect and/or antimicrobial effect and/or fungicidal effect and/or the plant-strengthening effect and/or the yield-increasing effect is substantially higher than the sum of the effects of the individual active ingredients.
• a synergistic effect will be present.
• inhibitors of the ergosterol biosynthesis selected from the group consisting of (1.001) cyproconazole, (1.002) difenoconazole, (1.003) epoxiconazole, (1.004) fenbuconazole, (1.005) fenhexamid, (1.006) fenpropidin, (1.007) fenpropimorph, (1.008) fenpyrazamine, (1.009) Fluoxytioconazole, (1.010) fluquinconazole, (1.011) flutriafol, (1.012) hexaconazole, (1.013) imazalil, (1.014) imazalil sulfate, (1.015) ipconazole, (1.016) ipfentrifluconazole, (1.017) mefentrifluconazole, (1.018) metconazole, (1.019) myclobutanil, (1.020) paclobutrazol, (1.021) penconazole, (1.022) prochlor
• inhibitors of the respiratory chain at complex I or II selected from the group consisting of (2.001) benzovindiflupyr, (2.002) bixafen, (2.003) boscalid, (2.004) carboxin, (2.005) cyclobutrifluram, (2.006) flubeneteram, (2.007) fluindapyr, (2.008) fluopyram, (2.009) flutolanil, (2.010) fluxapyroxad, (2.011) furametpyr, (2.012) inpyrfluxam, (2.013) Isofetamid, (2.014) isoflucypram, (2.015) isopyrazam, (2.016) penflufen, (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.019) pyrapropoyne, (2.020) pyraziflumid, (2.021) sedaxane, (2.022) Thifluzamide (aka trifluzamide), (2.023) 5,8-difluoro-
• inhibitors of the respiratory chain at complex III selected from the group consisting of (3.001) ametoctradin, (3.002) amisulbrom, (3.003) azoxystrobin, (3.004) coumethoxystrobin, (3.005) coumoxystrobin, (3.006) cyazofamid, (3.007) dimoxystrobin, (3.008) enoxastrobin, (3.009) famoxadone, (3.010) fenamidone, (3.011) fenpicoxamid, (3.012) florylpicoxamid, (3.013) flufenoxystrobin, (3.014) fluoxastrobin, (3.015) kresoxim-methyl, (3.016) mandestrobin, (3.017) metarylpicoxamid, (3.018) metominostrobin, (3.019) metyltetraprole, (3.020) orysastrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3
• inhibitors of the mitosis and cell division selected from the group consisting of (4.001) carbendazim, (4.002) diethofencarb, (4.003) ethaboxam, (4.004) fluopicolide, (4.005) fluopimomide, (4.006) metrafenone, (4.007) pencycuron, (4.008) pyridachlometyl, (4.009) pyriofenone (chlazafenone), (4.010) thiabendazole, (4.011) thiophanate-methyl, (4.012) zoxamide, (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)- 6-methylpyridazine, (4.014) 3-chloro-5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluoro- phenyl)pyridazine, (4.015) 4-(2-bromo-4-fluoroph
• (6) compounds capable to induce a host defence selected from the group consisting of (6.001) acibenzolar- S-methyl, (6.002) fosetyl-aluminium, (6.003) fosetyl-calcium, (6.004) fosetyl-sodium, (6.005) isotianil, (6.006) phosphorous acid and its salts, (6.007) probenazole and (6.008) tiadinil;
• inhibitors of the amino acid and/or protein biosynthesis selected from the group consisting of (7.001) cyprodinil, (7.002) kasugamycin, (7.003) kasugamycin hydrochloride hydrate, (7.004) oxytetracycline and (7.005) pyrimethanil; (8) inhibitors of the ATP production: (8.001) silthiofam;
• inhibitors of the cell wall synthesis selected from the group consisting of (9.001) benthiavalicarb, (9.002) dimethomorph, (9.003) flumorph, (9.004) iprovalicarb, (9.005) mandipropamid, (9.006) pyrimorph, (9.007) valifenalate, (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-l-(morpholin-4-yl)prop-2-en-l- one and (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-l-(morpholin-4-yl)prop-2-en-l-one;
• inhibitors of the lipid synthesis or transport, or membrane synthesis selected from the group consisting of (10.001) fluoxapiprolin, (10.002) natamycin, (10.003) oxathiapiprolin, (10.004) propamocarb, (10.005) propamocarb hydrochloride, (10.006) propamocarb-fosetylate, (10.007) tolclofos-methyl, (10.008) l-(4- ⁇ 4- [(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-l,2-oxazol-3-yl]-l,3-thiazol-2-yl ⁇ piperidin-l-yl)-2-[5-methyl-3- (trifluoromethyl)- 1 H-pyrazol- 1 -yl]ethanone, (10.009) 1 -(4- ⁇ 4- [(5S)-5-(2,6-difluorophenyl)-4,5-dihydro- 1
• inhibitors of the melanin biosynthesis selected from the group consisting of (11.001) tolprocarb and (11.002) tricyclazole;
• (12) inhibitors of the nucleic acid synthesis selected from the group consisting of (12.001) benalaxyl, (12.002) benalaxyl-M (kiralaxyl), (12.003) metalaxyl and (12.004) metalaxyl-M (mefenoxam);
• inhibitors of the signal transduction selected from the group consisting of (13.001) fludioxonil, (13.002) iprodione, (13.003) procymidone, (13.004) proquinazid, (13.005) quinoxyfen and (13.006) vinclozolin; (14) compounds capable to act as an uncoupler selected from the group consisting of (14.001) fluazinam and
• the active compounds of group (II) which are specified herein by their “common name” are known and described inter alia in "The Pesticide Manual", 16th edition, The British Crop Protection Council and the Royal Soc. of Chemistry, 2012 and the literature cited therein or can be searched in the internet (e.g. http://www.alanwood.net/pesticides). Particularly, reference shall be made to said Manual or website in order to further specify such a mixing partner of group (II), e.g. to provide its chemical structure, IUPAC name or its pesticidal activity. Further information about such a mixing partner of group (II) will be provided as well, in particular it's composition in case that the mixing partner of group (II) is itself a mixture, e.g. a mixture of enantiomers.
• the common name of an active compound this in each case encompasses all common derivatives, such as the esters and salts, and isomers, especially optical isomers, especially the commercial form or forms. If an ester or salt is referred to by the common name, this also refers in each case to all other common derivatives, such as other esters and salts, the free acids and neutral compounds, and isomers, especially optical isomers, especially the commercial form or forms.
• the chemical compound names mentioned refer to at least one of the compounds encompassed by the common name, frequently a preferred compound.
• the invention also relates to methods for controlling animal or microbial pests, in which active compound combinations according to the invention are allowed to act on the animal or microbial pests and/or their habitat.
• the animal pest is an insect or arachnid or acarid pest.
• control of the animal or microbial pests is preferably conducted in agriculture and forestry, and in material protection.
• Preferably excluded herefrom are methods for the surgical or therapeutic treatment of the human or animal body and diagnostic methods carried out on the human or animal body.
• the invention also relates to the use of active compound combinations according to the invention as pesticidal combinations, in particular crop protection agents.
• pesticidal combinations in particular crop protection agents.
• crop protection agents in particular crop protection agents.
• the term "pesticide” in each case also always comprises the term "crop protection agent”.
• the active compound combinations according to invention have also potent microbicidal activity and/or plant defense modulating potential. They can be used for controlling unwanted microorganisms, such as unwanted fungi and bacteria, on plants. They can be particularly useful in crop protection (they control microorganisms that cause plants diseases) or for protecting materials (e.g. industrial materials, timber, storage goods). More specifically, the active compound combinations according to the invention can be used to protect seeds, germinating seeds, emerged seedlings, plants, plant parts, fruits, harvest goods and/or the soil in which the plants grow from unwanted microorganisms. Control or controlling as used herein encompasses protective, curative and eradicative treatment of unwanted microorganisms.
• Unwanted microorganisms may be pathogenic bacteria, pathogenic virus, pathogenic oomycetes or pathogenic fungi, more specifically phytopathogenic bacteria, phytopathogenic virus, phytopathogenic oomycetes or phytopathogenic fungi. These phytopathogenic microorganims are the causal agents of a broad spectrum of plants diseases.
• the active compound combinations according to the invention can be used as fungicides.
• fungicide refers to a compound or composition (formulation) that can be used in crop protection for the control of unwanted fungi, such as Plasmodiophoromycetes, Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and Deuteromycetes and/or for the control of Oomycetes.
• the active compound combinations of the invention may also be used as antibacterial agent.
• they may be used in crop protection, for example for the control of unwanted bacteria, such as Pseudomonadaceae, Rhizobiaceae, Xanthomonadaceae, Enterobacteriaceae, Corynebacteriaceae and Streptomycetaceae.
• the present invention also relates to a method for controlling unwanted microorganisms, such as unwanted fungi, oomycetes and bacteria, on plants comprising the step of applying the active compound combinations according to the invention to the microorganisms and/or their habitat (to the plants, plant parts, seeds, fruits or to the soil in which the plants grow), wherein the active compound of formula (I) and active compounds of group (II) may be applied in a simultaneous, separate or sequential manner. If the single compounds are applied in a sequential manner, i.e. at different times, they are applied one after the other within a reasonably short period, such as a few hours or days.
• Suitable substrates that may be used for cultivating plants include inorganic based substrates, such as mineral wool, in particular stone wool, perlite, sand or gravel; organic substrates, such as peat, pine bark or sawdust; and petroleum based substrates such as polymeric foams or plastic beads.
• Effective and plant-compatible amount means an amount that is sufficient to control or destroy the fungi present or liable to appear on the cropland and that does not entail any appreciable symptom of phytotoxicity for said crops. Such an amount can vary within a wide range depending on the fungus to be controlled, the type of crop, the crop growth stage, the climatic conditions and the respective compound or composition (formulation) of the invention used. This amount can be determined by systematic field trials that are within the capabilities of a person skilled in the art.
• the active compound combinations according to the invention are preferably suitable for controlling animal and microbial pests.
• the active compound combinations according to the invention are particularly preferably suitable for controlling animal pests, especially insect or arachnid or acarid pests.
• the active compound combinations according to the invention are particularly preferably suitable for controlling microbial pests.
• the active compound combinations according to the invention are particularly preferably suitable for controlling nematodes.
• the active compound combinations according to the invention are particularly preferably suitable for controlling unwanted microorganism.
• the active compound combinations according to the invention are particularly preferably used as plantstrengthening agents.
• the active compound combinations according to the invention can, at certain concentrations or application rates, also be used as herbicides, safeners, growth regulators or agents to improve plant properties, or as microbicides, for example as fungicides, antimycotics, bactericides, viricides (including agents against viroids) or as agents against MLO (Mycoplasma-like organisms) and RLO (Rickettsia-like organisms). If appropriate, they can also be employed as intermediates or precursors for the synthesis of other active compound compositions.
• the invention also relates to a process for preparing a crop protection agent, characterized in that an active compound combination according to the invention is mixed with extenders and/or surfactants.
• the active compounds in the active compound combinations according to the invention are present in certain weight ratios.
• the weight ratios of the active compounds in the active compound combinations can be varied within a relatively wide range.
• the combinations according to the invention comprise an active compound (I) and an active compound of group (II) selected from Fungicide Groups (1) to (15) in the following preferred and more preferred mixing ratios:
• Preferred mixing ratio 125:1 to 1:125 such as 100:1 to 1:100 or 80:1 to 1:80.
• More preferred mixing ratio 40:1 to 1:80 such as 40:1 to 1:5 or 1:5 to 1:80 or even 20:1 to 1:60 or 20:1 to 1:50 or 15:1 to 1:50 or 10:1 to 1:50 or 5:1 to 1:25 or 2.5:1 to 1:10.
• the mixing ratios are based on weight ratios.
• the ratio is to be understood as meaning active compound of the formula (I) : an active compound of group (II). Additional mixing partners
• the active compound combinations according to the invention may contain one or more further active substances selected from a fungicide or an insecticide, i.e. at least one further fungicidally or insecticidally active additive.
• a further active additive is selected from the groups mentioned below.
• the active compounds identified here by their common names are known and are described, for example, in the pesticide handbook (“The Pesticide Manual” 16th Ed., British Crop Protection Council 2012) or can be found on the Internet (e.g. http://www.alanwood.net/pesticides). The classification is based on the current IRAC Mode of Action Classification Scheme at the time of filing of this patent application.
• Acetylcholinesterase (AChE) inhibitors preferably carbamates selected from alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC and xylylcarb, or organophosphates selected from acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos-methyl, cous
• GABA-gated chloride channel blockers preferably cyclodiene-organochlorines selected from chlordane and endosulfan, or phenylpyrazoles (fiproles) selected from ethiprole and fipronil.
• Sodium channel modulators preferably pyrethroids selected from acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin s-cyclopentenyl isomer, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin [(IR)-trans-isomer], deltamethrin, empenthrin [(EZ)-(lR)-isomer], esfenval
• Nicotinic acetylcholine receptor (nAChR) competitive modulators preferably neonicotinoids selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam, or nicotine, or sulfoximines selected from sulfoxaflor, or butenolids selected from flupyradifurone, or mesoionics selected from triflumezopyrim, or pyridylidenes selected from Flupyrimin.
• nAChR Nicotinic acetylcholine receptor
• Nicotinic acetylcholine receptor (nAChR) allosteric modulators site I, preferably spinosyns selected from spinetoram and spinosad.
• Glutamate-gated chloride channel (GluCl) allosteric modulators preferably avermectins/milbemycins selected from abamectin, emamectin benzoate, lepimectin and milbemectin.
• Juvenile hormone mimics preferably juvenile hormone analogues selected from hydroprene, kinoprene and methoprene, or fenoxycarb or pyriproxyfen.
• Miscellaneous non-specific (multi-site) inhibitors preferably alkyl halides selected from methyl bromide and other alkyl halides, or chloropicrine or sulphuryl fluoride or borax or tartar emetic or methyl isocyanate generators selected from diazomet and metam.
• Chordotonal organ TRPV channel modulators preferably pyridine azomethanes selected from pymetrozine and pyrifluquinazon, or pyropenes selected from afidopyropen.
• Microbial disruptors of the insect gut membranes selected from Bacillus thuringiensis subspecies israelensis, Bacillus sphaericus, Bacillus thuringiensis subspecies aizawai, Bacillus thuringiensis subspecies kurstaki, Bacillus thuringiensis subspecies tenebrionis, and B. t. plant proteins selected from Cry 1 Ab, Cry 1 Ac, CrylFa, Cry 1 A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb and Cry34Abl/35Abl.
• Inhibitors of mitochondrial ATP synthase preferably ATP disruptors selected from diafenthiuron, or organotin compounds selected from azocyclotin, cyhexatin and fenbutatin oxide, or propargite or tetradifon.
• Nicotinic acetylcholine receptor channel blockers selected from bensultap, cartap hydrochloride, thiocylam and thiosultap-sodium.
• Inhibitors of chitin biosynthesis type 1 selected from buprofezin.
• Moulting disruptors in particular for Diptera, i.e. dipterans selected from cyromazine.
• Ecdysone receptor agonists preferably diacylhydrazines selected from chromafenozide, halofenozide, methoxyfenozide and tebufenozide.
• Octopamine receptor agonists selected from amitraz.
• Mitochondrial complex III electron transport inhibitors selected from hydramethylnone, acequinocyl, fluacrypyrim and bifenazate.
• Mitochondrial complex I electron transport inhibitors preferably METI acaricides and insecticides selected from fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad and tolfenpyrad, or rotenone (Derris).
• Voltage-dependent sodium channel blockers preferably oxadiazines selected from indoxacarb, or semicarbazones selected from metaflumizone.
• Inhibitors of acetyl CoA carboxylase preferably tetronic and tetramic acid derivatives selected from spirodiclofen, spiromesifen, spiropidion and spirotetramat.
• Mitochondrial complex IV electron transport inhibitors preferably phosphides selected from aluminium phosphide, calcium phosphide, phosphine and zinc phosphide, or cyanides selected from calcium cyanide, potassium cyanide and sodium cyanide.
• Mitochondrial complex II electron transport inhibitors preferably /? ⁇ ?m-kctonitrilc derivatives selected from cyenopyrafen and cyflumetofen, or carboxanilides selected from pyflubumide.
• Ryanodine receptor modulators preferably diamides selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, flubendiamide and tetraniliprole.
• GABA-gated chlorid channel allosteric modulators preferably meta-diamides selected from broflanilide, or isoxazoles selected from fluxametamide and isocycloseram.
• Baculoviruses preferably Granuloviruses (GVs) selected from Cydia pomonella GV and Thaumatotibia leucotreta (GV), or Nucleopolyhedro viruses (NPVs) selected from Anticarsia gemmatalis MNPV, Flucypyriprole and Helicoverpa armigera NPV.
• GVs Granuloviruses
• NPVs Nucleopolyhedro viruses
• Nicotinic acetylcholine receptor allosteric modulators selected from GS-omega/kappa HXTX-Hvla peptide.
• Calcium-activated potassium channel KCa2 modulators selected from acynonapyr.
• Mitochondrial complex III electron transfer inhibitors selected from flometoquin.
• UNE Botanical essence including synthetic, extracts and unrefined oils with unknown or uncertain MoA (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Chenopodium ambrosioides near ambrosioides extract and fatty acid monoesters with glycerol or propanediol neem oil.
• UDF Fungal agents of unknown or uncertain MoA (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Beauveria bassiana strains, Metarhizium anisopliae strain F52, and Paecilomyces fumosoroseus Apopka strain 97.
• Non-specific mechanical and physical disruptors (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Diatomaceous earth, and mineral oil.
• Further active compounds selected from Afoxolaner, Benbenzaramine, Benzpyrimoxan, Chloroprallethrin, Cryolite, Cyclobutrifluram, Cycloxaprid, Cyetpyrafen, Cyhalodiamide, Cyproflanilide (CAS 2375110-88-4), Dicloromezotiaz, Dimpropyridaz, epsilon-Metofluthrin, epsilon-Momfluthrin, Fenmezoditiaz, Fluazaindolizine, Fluchlordiniliprole, Fluensulfone, Flufenerim, Flufenoxystrobin, Flufiprole, Fluhexafon, Fluopyram, Fluralaner, Fufenozide, Flupentiofenox, Flupyroxypyrim, Guadipyr, Heptafluthrin, Imidaclothiz, Indazapyroxamet, Iprodi
• the active compound combinations can preferably be used as pesticides. They are active against normally sensitive and resistant species and against all or some stages of development.
• the abovementioned pests include: pests from the phylum of the Arthropoda, in particular from the class of the Arachnida, for example Acarus spp., for example Acarus siro, Aceria kuko, Aceria sheldoni, Aculops spp., Aculus spp., for example Aculus fockeui, Aculus pointedendali, Amblyomma spp., Amphitetranychus viennensis, Argas spp., Boophilus spp., Brevipalpus spp., for example Brevipalpus phoenicis, Bryobia graminum, Bryobia praetiosa, Centruroides spp., Chorioptes spp., Dermanyssus gallinae, Dermatophagoides
• Nephotettix spp. Myzus nicotianae, Nasonovia ribisnigri, Neomaskellia spp., Nephotettix spp., for example Nephotettix cincticeps,, Nephotettix nigropictus, Nettigoniclla spectra, Nilaparvata lugens, Oncometopia spp., Orthezia praelonga, Oxya chinensis, Pachypsylla spp., Parabemisia myricae, Paratrioza spp., for example Paratrioza cockerelli, Parlatoria spp., Pemphigus spp., for example Pemphigus bursarius, Pemphigus populivenae, Peregrinus maidis, Perkinsiella spp., Phenacoccus spp., for example Phenacoccus madeirensis, Phloeomy
• phytoparasitic nematodes in particular Aglenchus spp., for example Aglenchus agricola, Anguina spp., for example Anguina tritici, Aphelenchoides spp., for example Aphelenchoides arachidis, Aphelenchoides fragariae, Belonolaimus spp., for example Belonolaimus gracilis, Belonolaimus longicaudatus, Belonolaimus nortoni, Bursaphelenchus spp., for example Bursaphelenchus cocophilus, Bursaphelenchus eremus, Bursaphelenchus xylophilus, Cacopaurus spp., for example Cacopaurus pestis, Criconemella spp., for example Criconemella curvata, Criconemella onoensis, Criconemella ornata, Criconemella rusium, Criconemella
• Non-limiting examples of pathogens of fungal diseases which may be treated in accordance with the invention include: diseases caused by powdery mildew pathogens, for example Blumeria species, for example Blumeria graminis', Podosphaera species, for example Podosphaera leucotricha', Sphaerotheca species, for example Sphaero theca fuliginea', Uncinula species, for example Erysiphe necator, diseases caused by rust disease pathogens, for example Gymnosporangium species, for example Gymnosporangium sabinae', Hemileia species, for example Hemileia vastatrix', Phakopsora species, for example Phakopsora pachyrhizi, Phakopsora meibomiae or Phakopsora euvitis', Puccinia species, for example Puccinia recondita, Puccinia graminis oder Puccinia strii
• brassicae' Phytophthora species, for example Phytophthora infestans'
• Plasmopara species for example Plasmopara viticola'
• Pseudoperonospora species for example Pseudoperonospora humuli or Pseudoperonospora cubensis'
• Pythium species for example Pythium ultimunr
• Cercospora species for example Cercospora beticola'
• Cladiosporium species for example Cladiosporium cucumerinunr
• Cochliobolus species for example Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium) or Cochliobolus miyabeanus'
• Colletotrichum species for example Colleto
• Pseudomonas species for example Pseudomonas syringae pv. lachrymans', Erwinia species, for example Erwinia amylovora', Liberibacter species, for example Liberibacter asiaticus', Xyella species, for example Xylella fastidiosa', Ralstonia species, for example Ralstonia solanacearum', Dickeya species, for example Dickeya solani', Clavibacter species, for example Clavibacter michiganensis', Streptomyces species, for example Streptomyces scabies. diseases of soya beans:
• Altemaria leaf spot Altemaria spec, atrans tenuissima
• Anthracnose Coldletotrichum gloeosporoides dematium var.
• phytophthora rot (Phytophthora megasperma), brown stem rot (Phialophora gregata), pythium rot (Pythium aphanidermatum, Pythium irregulare, Pythium debaryanum, Pythium myriotylum, Pythium ultimum), rhizoctonia root rot, stem decay, and damping-off (Rhizoctonia solani), sclerotinia stem decay (Sclerotinia sclerotiorum), sclerotinia southern blight (Sclerotinia rolfsii), thielaviopsis root rot (Thielaviopsis basicola).
• the compound combination and the composition (formulation) of the invention may reduce the mycotoxin content in the harvested material and the foods and feeds prepared therefrom.
• Mycotoxins include particularly, but not exclusively, the following: deoxynivalenol (DON), nivalenol, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxin, fumonisins, zearalenon, moniliformin, fusarin, diaceotoxyscirpenol (DAS), beauvericin, enniatin, fusaroproliferin, fusarenol, ochratoxins, patulin, ergot alkaloids and aflatoxins which can be produced, for example, by the following fungi: Fusarium spec., such as F.
• verticillioides and also by Aspergillus spec., such as A. flavus, A. parasiticus, A. nomius, A. ochraceus, A. clavatus, A. terreus, A. versicolor, Penicillium spec., such as P. verrucosum, P. viridicatum, P. citrinum, P. expansum, P. claviforme, P. roqueforti, Claviceps spec., such as C. purpurea, C. fusiformis, C. paspali, C. africana, Stachybotrys spec, and others.
• Aspergillus spec. such as A. flavus, A. parasiticus, A. nomius, A. ochraceus, A. clavatus, A. terreus, A. versicolor, Penicillium spec., such as P. verrucosum, P. viridicatum, P. citr
• the present invention further relates to formulations, in particular formulations for controlling unwanted animal and microbial pests as well as unwanted microorganism.
• the formulation may be applied to the animal pest and microbial pest and unwanted microorganism and/or in their habitat.
• the formulation of the invention may be provided to the end user as “ready-for-use” use form, i.e. the formulations may be directly applied to the plants or seeds by a suitable device, such as a spraying or dusting device.
• the formulations may be provided to the end user in the form of concentrates which have to be diluted, preferably with water, prior to use. Unless otherwise indicated, the wording “formulation” therefore means such concentrate, whereas the wording “use form” means the end user as “ready-for-use” solution, i.e. usually such diluted formulation.
• the formulation of the invention can be prepared in conventional manners, for example by mixing the active compound combination of the invention with one or more suitable auxiliaries, such as disclosed herein.
• the formulation comprises at least one active compound combination of the invention and at least one agriculturally suitable auxiliary, e.g. carrier(s) and/or surfactant(s).
• agriculturally suitable auxiliary e.g. carrier(s) and/or surfactant(s).
• a carrier is a solid or liquid, natural or synthetic, organic or inorganic substance that is generally inert.
• the carrier generally improves the application of the compounds, for instance, to plants, plants parts or seeds.
• suitable solid carriers include, but are not limited to, ammonium salts, in particular ammonium sulfates, ammonium phosphates and ammonium nitrates, natural rock flours, such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite and diatomaceous earth, silica gel and synthetic rock flours, such as finely divided silica, alumina and silicates.
• typically useful solid carriers for preparing granules include, but are not limited to crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, synthetic granules of inorganic and organic flours and granules of organic material such as paper, sawdust, coconut shells, maize cobs and tobacco stalks.
• suitable liquid carriers include, but are not limited to, water, organic solvents and combinations thereof.
• suitable solvents include polar and nonpolar organic chemical liquids, for example from the classes of aromatic and nonaromatic hydrocarbons (such as cyclohexane, paraffins, alkylbenzenes, xylene, toluene, tetrahydronaphthalene, alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride), alcohols and polyols (which may optionally also be substituted, etherified and/or esterified, such as ethanol, propanol, butanol, benzylalcohol, cyclohexanol or glycol), ketones (such as acetone, methyl ethyl ketone, methyl isobutyl ketone, acetophenone, or cyclohexanone), esters (including fats and oils) and (poly)ethers, unsubstituted and substituted
• the carrier may also be a liquefied gaseous extender, i.e. liquid which is gaseous at standard temperature and under standard pressure, for example aerosol propellants such as halohydrocarbons, butane, propane, nitrogen and carbon dioxide.
• a liquefied gaseous extender i.e. liquid which is gaseous at standard temperature and under standard pressure
• aerosol propellants such as halohydrocarbons, butane, propane, nitrogen and carbon dioxide.
• Preferred solid carriers are selected from clays, talc and silica.
• Preferred liquid carriers are selected from water, fatty acid amides and esters thereof, aromatic and nonaromatic hydrocarbons, lactams, lactones, carbonic acid esters, ketones, (poly)ethers.
• the amount of carrier typically ranges from 1 to 99.99%, preferably from 5 to 99.9%, more preferably from 10 to 99.5%, and most preferably from 20 to 99% by weight of the formulation.
• Liquid carriers are typically present in a range of from 20 to 90%, for example 30 to 80% by weight of the formulation.
• Solid carriers are typically present in a range of from 0 to 50%, preferably 5 to 45%, for example 10 to 30% by weight of the formulation.
• the formulation comprises two or more carriers, the outlined ranges refer to the total amount of carriers.
• the surfactant can be an ionic (cationic or anionic), amphoteric or non-ionic surfactant, such as ionic or non-ionic emulsifier (s), foam former(s), dispersant(s), wetting agent(s), penetration enhancer(s) and any mixtures thereof.
• surfactants include, but are not limited to, salts of polyacrylic acid, ethoxylated polya(alpha-substituted)acrylate derivatives, salts of lignosulfonic acid (such as sodium lignosulfonate), salts of phenolsulfonic acid or naphthalenesulfonic acid, polycondensates of ethylene oxide and/or propylene oxide with or without alcohols, fatty acids or fatty amines (for example, polyoxyethylene fatty acid esters such as castor oil ethoxylate, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers), substituted phenols (preferably alkylphenols or arylphenols), salts of sulfosuccinic esters, taurine derivatives (preferably alkyl taurates), phosphoric esters of polyethoxylated alcohols or phenols, fatty esters of polyols (such a fatty acid esters of g
• Preferred surfactants are selected from ethoxylated polya(alpha-substituted)acrylate derivatives, polycondensates of ethylene oxide and/or propylene oxide with alcohols, polyoxyethylene fatty acid esters, alkylbenzene sulfonates, sulfonated polymers of naphthalene/formaldehyde, polyoxyethylene fatty acid esters such as castor oil ethoxylate, sodium lignosulfonate and arylphenol ethoxylate.
• the amount of surfactants typically ranges from 5 to 40%, for example 10 to 20%, by weight of the formulation.
• suitable auxiliaries include water repellents, siccatives, binders (adhesive, tackifier, fixing agent, such as carboxymethylcellulose, natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, natural phospholipids such as cephalins and lecithins and synthetic phospholipids, polyvinylpyrrolidone and tylose), thickeners and secondary thickeners (such as cellulose ethers, acrylic acid derivatives, xanthan gum, modified clays, e.g.
• stabilizers e.g. cold stabilizers, preservatives (e.g. dichlorophene, benzyl alcohol hemiformal, l,2-Benzisothiazolin-3-on, 2- methyl-4-isothiazolin-3-one), antioxidants, light stabilizers, in particular UV stabilizers, or other agents which improve chemical and/or physical stability
• dyes or pigments such as inorganic pigments, e.g. iron oxide, titanium oxide and Prussian Blue; organic dyes, e.g. alizarin, azo and metal phthalocyanine dyes), antifoams (e.g.
• silicone antifoams and magnesium stearate silicone antifoams and magnesium stearate
• antifreezes stickers, gibberellins and processing auxiliaries, mineral and vegetable oils, perfumes, waxes, nutrients (including trace nutrients, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc), protective colloids, thixotropic substances, penetrants, sequestering agents and complex formers.
• auxiliaries depends on the intended mode of application of the active compound combination of the invention and/or on the physical properties of the compound(s). Furthermore, the auxiliaries may be chosen to impart particular properties (technical, physical and/or biological properties) to the formulations or use forms prepared therefrom. The choice of auxiliaries may allow customizing the formulations to specific needs.
• the formulation comprises an insecticidal/fungicidal/acaricidal/nematicidal effective amount of the active compound combination of the invention.
• effective amount denotes an amount, which is sufficient for controlling harmful insects/mites/nematodes/fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the insect/mite/nematode/fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific active compound combination of the invention used.
• the formulation according to the invention contains from 0.01 to 99% by weight, preferably from 0.05 to 98% by weight, more preferred from 0.1 to 95% by weight, even more preferably from 0.5 to 90% by weight, most preferably from 1 to 80% by weight of the active compound combination of the invention.
• the outlined ranges refer to the total amount of active compound of formula (I) and active compounds of group (II) present in the active compound combination according to the invention.
• the formulation of the invention may be in any customary formulation type, such as solutions (e.g aqueous solutions), emulsions, water- and oil-based suspensions, powders (e.g. wettable powders, soluble powders), dusts, pastes, granules (e.g. soluble granules, granules for broadcasting), suspoemulsion concentrates, natural or synthetic products impregnated with the active compound combination of the invention, fertilizers and also microencapsulations in polymeric substances.
• the active compound combination of the invention may be present in a suspended, emulsified or dissolved form. Examples of particular suitable formulation types are solutions, watersoluble concentrates (e.g.
• SL LS
• dispersible concentrates DC
• suspensions and suspension concentrates e.g. SC, OD, OF, FS
• emulsifiable concentrates e.g. EC
• emulsions e.g. EW, EO, ES, ME, SE
• capsules e.g. CS, ZC
• pastes pastilles
• wettable powders or dusts e.g. WP, SP, WS, DP, DS
• pressings e.g. BR, TB, DT
• granules e.g. WG, SG, GR, FG, GG, MG
• insecticidal articles e.g.
• the formulation of the invention is in form of one of the following types: EC, SC, FS, SE, OD, WG, WP, CS, more preferred EC, SC, OD, WG, CS.
• active compound combination according to the invention in the examples of formulation types and their preparation given below refer to the total amount of active compound of formula (I) and active compounds of group (II) present in the active compound combination according to the invention. This applies mutatis mutandis for any further component of the formulation, if two or more representatives of such component, e.g. surfactant, wetting agent, binder, are present.
• surfactant e.g. surfactant, wetting agent, binder
• surfactant e.g. polycondensates of ethylene oxide and/or propylene oxide with alcohols
• water and/or water-soluble solvent e.g. alcohols such as propylene glycol or carbonates such as propylene carbonate
• DC Dispersible concentrates
• ком ⁇ онент 5-40 % by weight of the active compound combination according to the invention and 1-10 % by weight surfactant (e.g. a mixture of calcium dodecylbenzenesulfonate and castor oil ethoxylate, or polycondensates of ethylene oxide and/or propylene oxide with or without alcohols) are dissolved in 20- 40 % by weight water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is added to such amount of water by means of an emulsifying machine to result in a total amount of 100 % by weight. The resulting formulation is a homogeneous emulsion. Before application the emulsion may be further diluted with water.
• a suitable grinding equipment e.g. an agitated ball mill
• 20-60 % by weight of the active compound combination according to the invention are comminuted with addition of 2-10 % by weight surfactant (e.g. sodium lignosulfonate and polyoxyethylene fatty alcohol ether), 0.1-2 % by weight thickener (e.g. xanthan gum) and water to give a fine active substance suspension.
• surfactant e.g. sodium lignosulfonate and polyoxyethylene fatty alcohol ether
• thickener e.g. xanthan gum
• water e.g. xanthan gum
• the water is added in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable suspension of the active substances.
• binder e.g. polyvinylalcohol
• a suitable grinding equipment e.g. an agitated ball mill
• 20-60 % by weight of the active compound combination according to the invention of the invention are comminuted with addition of 2-10 % by weight surfactant (e.g. sodium lignosulfonate and polyoxyethylene fatty alcohol ether), 0.1-2 % by weight thickener (e.g. modified clay, in particular Bentone, or silica) and an organic carrier to give a fine active substance oil suspension.
• the organic carrier is added in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion of the active substances.
• % by weight, preferably 20-80%, most preferably 50-80 % by weight of the active compound combination according to the invention are ground finely with addition of surfactant (e.g. sodium lignosulfonate and sodium alkylnaphthylsulfonates) and potentially carrier material and converted to water-dispersible or water-soluble granules by means of typical technical appliances like e.g. extrusion, spray drying, fluidized bed granulation.
• surfactant and carrier material are used in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion or solution of the active substances.
• Water-dispersible powders and water-soluble powders (WP, SP, WS) 50-80 % by weight of the active compound combination according to the invention are ground in a rotorstator mill with addition of 1-20 % by weight surfactant (e.g. sodium lignosulfonate, sodium alkylnaphthylsulfonates) and such amount of solid carrier, e.g. silica gel, to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion or solution of the active substances.
• surfactant e.g. sodium lignosulfonate, sodium alkylnaphthylsulfonates
• solid carrier e.g. silica gel
• % by weight of the active compound combination according to the invention are comminuted with addition of 3-10 % by weight surfactant (e.g. sodium lignosulfonate), 1-5 % by weight binder (e.g. carboxymethylcellulose) and such amount of water to result in a total amount of 100 % by weight.
• surfactant e.g. sodium lignosulfonate
• binder e.g. carboxymethylcellulose
• % by weight of the active compound combination according to the invention are added to 5-30 % by weight organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 % by weight surfactant blend (e.g. polyoxyethylene fatty alcohol ether and arylphenol ethoxylate), and such amount of water to result in a total amount of 100 % by weight.
• organic solvent blend e.g. fatty acid dimethylamide and cyclohexanone
• surfactant blend e.g. polyoxyethylene fatty alcohol ether and arylphenol ethoxylate
• An oil phase comprising 5-50 % by weight of the active compound combination according to the invention, 0-40 % by weight water-insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 % by weight acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(meth)acrylate microcapsules.
• an oil phase comprising 5-50 % by weight of the active compound combination according to the invention, 0- 40 % by weight water-insoluble organic solvent (e.g.
• the formulations types i) to xiii) may optionally comprise further auxiliaries, such as 0.1-1 % by weight preservatives, 0.1-1 % by weight antifoams, 0.1-1 % by weight dyes and/or pigments, and 5-10% by weight antifreezes.
• plants are to be understood to mean all plants and plant parts such as wanted and unwanted wild plants or crop plants (including naturally occurring crop plants), for example cereals (wheat, rice, triticale, barley, rye, oats), maize, soya bean, potato, sugar beet, sugar cane, tomatoes, pepper, cucumber, melon, carrot, watermelon, onion, lettuce, spinach, leek, beans, Brassica oleracea (e.g. cabbage) and other vegetable species, cotton, tobacco, oilseed rape, and also fruit plants (with the fruits apples, pears, citrus fruits and grapevines).
• cereals wheat, rice, triticale, barley, rye, oats
• soya bean potato
• sugar beet sugar cane
• tomatoes pepper, cucumber, melon, carrot
• watermelon onion
• lettuce spinach
• leek beans
• Brassica oleracea e.g. cabbage
• other vegetable species cotton, tobacco, oilseed rape, and also
• Crop plants can be plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of these methods, including the transgenic plants and including the plant varieties which can or cannot be protected by varietal property rights.
• Plants should be understood to mean all developmental stages, such as seeds, seedlings, young (immature) plants up to mature plants.
• Plant parts should be understood to mean all parts and organs of the plants above and below ground, such as shoot, leaf, flower and root, examples given being leaves, needles, stalks, stems, flowers, fruit bodies, fruits and seeds, and also tubers, roots and rhizomes. Parts of plants also include harvested plants or harvested plant parts and vegetative and generative propagation material, for example seedlings, tubers, rhizomes, cuttings and seeds.
• Treatment according to the invention of the plants and plant parts with the active compound combination according to the invention is carried out directly or by allowing the compounds to act on the surroundings, environment or storage space by the customary treatment methods, for example by immersion, spraying, evaporation, fogging, scattering, painting on, injection and, in the case of propagation material, in particular in the case of seeds, also by applying one or more coats.
• plants and their parts are treated.
• wild plant species and plant cultivars, or those obtained by conventional biological breeding methods, such as crossing or protoplast fusion, and also parts thereof are treated.
• transgenic plants and plant cultivars obtained by genetic engineering methods, if appropriate in combination with conventional methods (genetically modified organisms), and parts thereof are treated.
• the term “parts” or “parts of plants” or “plant parts” has been explained above.
• the invention is used with particular preference to treat plants of the respective commercially customary cultivars or those that are in use.
• Plant cultivars are to be understood as meaning plants having new properties ("traits") and which have been obtained by conventional breeding, by mutagenesis or by recombinant DNA techniques. They can be cultivars, varieties, bio- or genotypes.
• the active compound combination according to the invention can be advantageously used to treat transgenic plants, plant cultivars or plant parts that received genetic material which imparts advantageous and/or useful properties (traits) to these plants, plant cultivars or plant parts. Therefore, it is contemplated that the present invention may be combined with one or more recombinant traits or transgenic event(s) or a combination thereof.
• a transgenic event is created by the insertion of a specific recombinant DNA molecule into a specific position (locus) within the chromosome of the plant genome.
• the insertion creates a novel DNA sequence referred to as an “event” and is characterized by the inserted recombinant DNA molecule and some amount of genomic DNA immediately adjacent to/flanking both ends of the inserted DNA.
• trait(s) or transgenic event(s) include, but are not limited to, pest resistance, water use efficiency, yield performance, drought tolerance, seed quality, improved nutritional quality, hybrid seed production, and herbicide tolerance, in which the trait is measured with respect to a plant lacking such trait or transgenic event.
• Such advantageous and/or useful properties are better plant growth, vigor, stress tolerance, standability, lodging resistance, nutrient uptake, plant nutrition, and/or yield, in particular improved growth, increased tolerance to high or low temperatures, increased tolerance to drought or to levels of water or soil salinity, enhanced flowering performance, easier harvesting, accelerated ripening, higher yields, higher quality and/or a higher nutritional value of the harvested products, better storage life and/or processability of the harvested products, and increased resistance or tolerance against animal and microbial pests, such as against insects, arachnids, nematodes, mites, slugs and snails.
• animal and microbial pests such as against insects, arachnids, nematodes, mites, slugs and snails.
• Bt Cry or VIP proteins which include the CrylA, CrylAb, CrylAc, CryllA, CrylllA, CryIIIB2, Cry9c Cry2Ab, Cry3Bb and CrylF proteins or toxic fragments thereof and also hybrids or combinations thereof, especially the CrylF protein or hybrids derived from a CrylF protein (e.g. hybrid CrylA-CrylF proteins or toxic fragments thereof), the CrylA-type proteins or toxic fragments thereof, preferably the CrylAc protein or hybrids derived from the CrylAc protein (e.g.
• hybrid CrylAb-CrylAc proteins or the CrylAb or Bt2 protein or toxic fragments thereof, the Cry2Ae, Cry2Af or Cry2Ag proteins or toxic fragments thereof, the CrylA.105 protein or a toxic fragment thereof, the VIP3Aal9 protein, the VIP3Aa20 protein, the VIP3A proteins produced in the COT202 or COT203 cotton events, the VIP3Aa protein ora toxic fragment thereof as described in Estruch et al. (1996), Proc Natl Acad Sci US A.
• Another and particularly emphasized example of such properties is conferred tolerance to one or more herbicides, for example imidazolinones, sulphonylureas, glyphosate or phosphinothricin.
• herbicides for example imidazolinones, sulphonylureas, glyphosate or phosphinothricin.
• DNA sequences encoding proteins which confer properties of tolerance to certain herbicides on the transformed plant cells and plants mention will be particularly be made to the bar or PAT gene or the Streptomyces coelicolor gene described in WO2009/152359 which confers tolerance to glufosinate herbicides, a gene encoding a suitable EPSPS (5-enolpyruvylshikimat-3-phosphat-synthase) which confers tolerance to herbicides having EPSPS as a target, especially herbicides such as glyphosate and its salts, a gene encoding glyphosate-n
• herbicide tolerance traits include at least one ALS (acetolactate synthase) inhibitor (e.g. W02007/024782), a mutated Arabidopsis ALS/AHAS gene (e.g. U.S. Patent 6,855,533), genes encoding 2,4-D- monooxygenases conferring tolerance to 2,4-D (2,4- dichlorophenoxyacetic acid) and genes encoding Dicamba monooxygenases conferring tolerance to dicamba (3,6-dichloro-2- methoxybenzoic acid).
• ALS acetolactate synthase
• W02007/024782 e.g. W02007/024782
• a mutated Arabidopsis ALS/AHAS gene e.g. U.S. Patent 6,855,533
• Yet another example of such properties is resistance to one or more phytopathogenic fungi, for example Asian Soybean Rust.
• DNA sequences encoding proteins which confer properties of resistance to such diseases mention will particularly be made of the genetic material from glycine tomentella, for example from any one of publically available accession lines PI441001 , PI483224, PI583970, PI446958, PI499939, PI505220, PI499933, PI441008, PI505256 or PI446961 as described in W02019/103918.
• Such properties are increased resistance against phytopathogenic fungi, bacteria and/or viruses owing, for example, to systemic acquired resistance (SAR), systemin, phytoalexins, elicitors and also resistance genes and correspondingly expressed proteins and toxins.
• SAR systemic acquired resistance
• systemin phytoalexins
• elicitors resistance genes and correspondingly expressed proteins and toxins.
• Particularly useful transgenic events in transgenic plants or plant cultivars which can be treated with preference in accordance with the invention include Event 531/ PV-GHBK04 (cotton, insect control, described in W02002/040677), Event 1143-14A (cotton, insect control, not deposited, described in WO2006/128569); Event 1143-51B (cotton, insect control, not deposited, described in W02006/128570); Event 1445 (cotton, herbicide tolerance, not deposited, described in US-A 2002- 120964 or W02002/034946); Event 17053 (rice, herbicide tolerance, deposited as PTA-9843, described in WO2010/117737); Event 17314 (rice, herbicide tolerance, deposited as PTA-9844, described in WO2010/117735); Event 281-24-236 (cotton, insect control - herbicide tolerance, deposited as PTA-6233, described in W02005/103266 or US-A 2005-216969); Event 3006-210-23 (cotton, insect control - herb
• Event BLR1 (oilseed rape, restoration of male sterility, deposited as NCIMB 41193, described in W02005/074671), Event CE43-67B (cotton, insect control, deposited as DSM ACC2724, described in US-A 2009-217423 or WO2006/128573); Event CE44-69D (cotton, insect control, not deposited, described in US-A 2010- 0024077); Event CE44-69D (cotton, insect control, not deposited, described in WO2006/128571); Event CE46-02A (cotton, insect control, not deposited, described in WO2006/128572); Event COT102 (cotton, insect control, not deposited, described in US-A 2006-130175 or W02004/039986); Event COT202 (cotton, insect control, not deposited, described in US-A 2007-067868 or W02005/054479); Event COT203 (cotton, insect control, not deposited, described, described in US-A 2007-067868 or
• event pDAB8264.42.32.1 sibean, stacked herbicide tolerance, ATCC Accession N° PTA-11993, WO2013/010094 Al
• event MZDT09Y corn, ATCC Accession N° PTA- 13025, WO2013/012775A1.
• transgenic event(s) is provided by the United States Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) and can be found on their website at https://www.aphis.usda.gov/. For this application, the status of such list as it is/was on the filing date of this application, is relevant.
• USDA United States Department of Agriculture
• APIHIS Animal and Plant Health Inspection Service
• transgenic plants which may be mentioned are the important crop plants, such as cereals (wheat, rice, triticale, barley, rye, oats), maize, soya beans, potatoes, sugar beet, sugar cane, tomatoes, peas and other types of vegetable, cotton, tobacco, oilseed rape and also fruit plants (with the fruits apples, pears, citrus fruits and grapes), with particular emphasis being given to maize, soya beans, wheat, rice, potatoes, cotton, sugar cane, tobacco and oilseed rape.
• Traits which are particularly emphasized are the increased resistance of the plants to insects, arachnids, nematodes and slugs and snails, as well as the increased resistance of the plants to one or more herbicides.
• the treatment of the plants and plant parts with the active compound combination according to the invention is carried out directly or by action on their surroundings, habitat or storage space using customary treatment methods, for example by dipping, spraying, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, foaming, painting, spreading-on, injecting, watering (drenching), drip irrigating and, in the case of propagation material, in particular in the case of seed, furthermore as a powder for dry seed treatment, a solution for liquid seed treatment, a water-soluble powder for slurry treatment, by incrusting, by coating with one or more coats, etc. It is furthermore possible to apply the active compound combination according to the invention by the ultra-low volume method or to inject the application form or the active compound combination according to the invention itself into the soil.
• a preferred direct treatment of the plants is foliar application, i.e. the active compound combination according to the invention is applied to the foliage, where treatment frequency and the application rate should be adjusted according to the level of infestation with the pest in question.
• the active compound combination according to the invention also access the plants via the root system.
• the plants are then treated by the action of the active compound combination according to the invention on the habitat of the plant. This may be done, for example, by drenching, or by mixing into the soil or the nutrient solution, i.e. the locus of the plant (e.g. soil or hydroponic systems) is impregnated with a liquid form of the active compound combination according to the invention, or by soil application, i.e. the active compound combination according to the invention is introduced in solid form (e.g. in the form of granules) into the locus of the plants, or by drip application (often also referred to as "chemigation"), i.e.
• the liquid application of the active compound combination according to the invention from surface or sub-surface driplines over a certain period of time together with varying amounts of water at defined locations in the vicinity of the plants.
• this can also be done by metering the active compound combination according to the invention in a solid application form (for example as granules) into a flooded paddy field.
• the active compound combination of the invention can be used in combination with models e.g. embedded in computer programs for site specific crop management, satellite farming, precision farming or precision agriculture.
• models support the site specific management of agricultural sites with data from various sources such as soils, weather, crops (e.g. type, growth stage, plant health), weeds (e.g. type, growth stage), diseases, pests, nutrients, water, moisture, biomass, satellite data, yield etc. with the purpose to optimize profitability, sustainability and protection of the environment.
• crops e.g. type, growth stage, plant health
• weeds e.g. type, growth stage
• diseases, pests, nutrients, water, moisture, biomass, satellite data, yield etc. with the purpose to optimize profitability, sustainability and protection of the environment.
• such models can help to optimize agronomical decisions, control the precision of pesticide/fungicide applications and record the work performed.
• the active compound combination of the invention can be applied to a crop plant according to an appropriate dose regime if a model models the development of a pest and calculates that a threshold has been reached for which it is recommendable to apply the active compound combination of the invention to the crop plant.
• Commercially available systems which include agronomic models are e.g. FieldScriptsTM from The climate Corporation, XarvioTM from BASF, AGLogicTM from John Deere, etc.
• the active compound combination of the invention can also be used in combination with smart spraying equipment such as e.g. spot spraying or precision spraying equipment attached to or housed within a farm vehicle such as a tractor, robot, helicopter, airplane, unmanned aerial vehicle (UAV) such as a drone, etc.
• a farm vehicle such as a tractor, robot, helicopter, airplane, unmanned aerial vehicle (UAV) such as a drone, etc.
• UAV unmanned aerial vehicle
• Such an equipment usually includes input sensors (such as e.g. a camera) and a processing unit configured to analyze the input data and configured to provide a decision based on the analysis of the input data to apply the active compound combination of the invention to the crop plants (respectively the weeds) in a specific and precise manner.
• the use of such smart spraying equipment usually also requires positions systems (e.g. GPS receivers) to localize recorded data and to guide or to control farm vehicles; geographic information systems (GIS) to represent the information on intelligible maps, and appropriate farm vehicles to perform the
• pests can be detected from imagery acquired by a camera.
• the pests can be identified and/or classified based on that imagery.
• identification and/ classification can make use of image processing algorithms.
• image processing algorithms can utilize machine learning algorithms, such as trained neutral networks, decision trees and utilize artificial intelligence algorithms. In this manner, the active compound combination according to the invention can be applied only where needed.
• methods for the treatment of seed should also take into consideration the intrinsic insecticidal or nematicidal properties of pest-resistant or -tolerant transgenic plants in order to achieve optimum protection of the seed and also the germinating plant with a minimum of pesticides being employed.
• the present invention therefore in particular also relates to a method for the protection of seed and germinating plants, from attack by pests or from unwanted microorgansim, by treating the seed with an active compound combination according to the invention.
• the method according to the invention for protecting seed and germinating plants against attack by pests or from unwanted microorganism furthermore comprises a method where the seed is treated simultaneously in one operation or sequentially with the compound of formula (I) and a mixing partner of group (II). It also comprises a method where the seed is treated at different times with a compound of the formula (I) and a mixing partner of group (II).
• the invention likewise relates to the use of the active compound combination according to the invention for the treatment of seed for protecting the seed and the resulting plant from animal and microbial pests as well as unwanted microorganism.
• the invention relates to seed which has been treated with an active compound combination according to the invention so as to afford protection from animal and microbial pests as well as unwanted microorganism.
• the invention also relates to seed which has been treated simultaneously with a compound of the formula (I) and a mixing partner of group (II).
• the invention furthermore relates to seed which has been treated at different times with a compound of the formula (I) and a mixing partner of group (II).
• the individual substances may be present on the seed in different layers.
• the layers comprising a compound of the formula (I) and mixing partner of group (II) may optionally be separated by an intermediate layer.
• the invention also relates to seed where a compound of the formula (I) and a mixing partner of group (II) have been applied as component of a coating or as a further layer or further layers in addition to a coating.
• the invention relates to seed which, after the treatment with an active compound combination according to the invention, is subjected to a film-coating process to prevent dust abrasion on the seed.
• One of the advantages encountered with a systemically acting active compound combination according to the invention is the fact that, by treating the seed, not only the seed itself but also the plants resulting therefrom are, after emergence, protected against animal and microbial pests as well as unwanted microorganism. In this manner, the immediate treatment of the crop at the time of sowing or shortly thereafter can be dispensed with.
• an active compound combination according to the invention can be used in particular also for transgenic seed.
• active compound combinations according to the invention can be employed in combination with compositions or compounds of signalling technology, leading to better colonization by symbionts such as, for example, rhizobia, mycorrhizae and/or endophytic bacteria or, and/or to optimized nitrogen fixation.
• symbionts such as, for example, rhizobia, mycorrhizae and/or endophytic bacteria or, and/or to optimized nitrogen fixation.
• the active compound combinations according to the invention are suitable for protection of seed of any plant variety which is used in agriculture, in the greenhouse, in forests or in horticulture.
• this takes the form of seed of cereals (for example wheat, barley, rye, millet and oats), corn, cotton, soya beans, rice, potatoes, sunflowers, coffee, tobacco, canola, oilseed rape, beets (for example sugarbeets and fodder beets), peanuts, vegetables (for example tomatoes, cucumbers, bean, cruciferous vegetables, onions and lettuce), fruit plants, lawns and ornamental plants.
• cereals for example wheat, barley, rye and oats
• transgenic seed with an active compound combination is also of particular importance.
• This takes the form of seed of plants which, as a rule, comprise at least one heterologous gene which governs the expression of a polypeptide with in particular insecticidal and/or nematicidal properties.
• the heterologous genes in transgenic seed can originate from microorganisms such as Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, Clavibacter, Glomus or Gliocladium.
• the present invention is particularly suitable for the treatment of transgenic seed which comprises at least one heterologous gene originating from Bacillus sp. It is particularly preferably a heterologous gene derived from Bacillus thuringiensis.
• the active compound combination according to the invention is applied to the seed.
• the seed is treated in a state in which it is stable enough to avoid damage during treatment.
• the seed may be treated at any point in time between harvest and sowing.
• the seed usually used has been separated from the plant and freed from cobs, shells, stalks, coats, hairs or the flesh of the fruits.
• seed which has been harvested, cleaned and dried down to a moisture content which allows storage.
• the amount of the active compound combination according to the invention applied to the seed and/or the amount of further additives is chosen in such a way that the germination of the seed is not adversely affected, or that the resulting plant is not damaged. This must be ensured particularly in the case of active compounds which can exhibit phytotoxic effects at certain application rates.
• the active compound combinations according to the invention are applied to the seed in a suitable formulation.
• suitable formulations and processes for seed treatment are known to the person skilled in the art.
• the active compound combinations according to the invention can be converted to the customary seed dressing formulations, such as solutions, emulsions, suspensions, powders, foams, slurries or other coating compositions for seed, and also ULV formulations.
• formulations are prepared in a known manner, by mixing the active compound combinations according to the invention with customary additives such as, for example, customary extenders and also solvents or diluents, colorants, wetting agents, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, adhesives, gibberellins and also water.
• customary additives such as, for example, customary extenders and also solvents or diluents, colorants, wetting agents, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, adhesives, gibberellins and also water.
• Colorants which may be present in the seed-dressing formulations which can be used in accordance with the invention are all colorants which are customary for such purposes. It is possible to use either pigments, which are sparingly soluble in water, or dyes, which are soluble in water. Examples include the dyes known by the names Rhodamine B, C.I. Pigment Red 112 and C.I. Solvent Red 1.
• Useful wetting agents which may be present in the seed dressing formulations usable in accordance with the invention are all substances which promote wetting, and which are conventionally used for the formulation of agrochemically active compounds. Preference is given to using alkylnaphthalenesulphonates, such as diisopropyl- or diisobutylnaphthalenesulphonates.
• Useful dispersants and/or emulsifiers which may be present in the seed dressing formulations usable in accordance with the invention are all nonionic, anionic and cationic dispersants conventionally used for the formulation of active agrochemical ingredients. Preference is given to using nonionic or anionic dispersants or mixtures of nonionic or anionic dispersants.
• Suitable nonionic dispersants include in particular ethylene oxide/propylene oxide block polymers, alkylphenol poly glycol ethers and tristryrylphenol polyglycol ethers, and the phosphated or sulphated derivatives thereof.
• Suitable anionic dispersants are in particular lignosulphonates, polyacrylic acid salts and arylsulphonate/formaldehyde condensates.
• Antifoams which may be present in the seed dressing formulations usable in accordance with the invention are all foam-inhibiting substances conventionally used for the formulation of active agrochemical ingredients. Preference is given to using silicone antifoams and magnesium stearate.
• Preservatives which may be present in the seed dressing formulations usable in accordance with the invention are all substances usable for such purposes in agrochemical compositions. Examples include dichlorophene and benzyl alcohol hemiformal.
• the gibberellins are known (cf. R. Wegler "Chemie der convinced- and Schadlingsbekampfungsstoff", vol. 2, Springer Verlag, 1970, pp. 401-412).
• the seed dressing formulations usable in accordance with the invention can be used to treat a wide variety of different kinds of seed either directly or after prior dilution with water.
• the concentrates or the preparations obtainable therefrom by dilution with water can be used to dress the seed of cereals, such as wheat, barley, rye, oats, and triticale, and also the seed of maize, rice, oilseed rape, peas, beans, cotton, sunflowers, soya beans and beets, or else a wide variety of different vegetable seed.
• the seed dressing formulations usable in accordance with the invention, or the dilute use forms thereof, can also be used to dress seed of transgenic plants.
• the procedure in the seed dressing is to place the seed into a mixer, operated batch- wise or continously, to add the particular desired amount of seed dressing formulations, either as such or after prior dilution with water, and to mix everything until the formulation is distributed homogeneously on the seed. If appropriate, this is followed by a drying operation.
• the application rate of the seed dressing formulations usable in accordance with the invention can be varied within a relatively wide range. It is guided by the particular content of the active compound combinations according to the invention in the formulations and by the seed.
• the application rates of the active compound combinations according to the invention are generally between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 15 g per kilogram of seed.
• a vector is an arthropod, in particular an insect or arachnid, capable of transmitting pathogens such as, for example, viruses, worms, single-cell organisms and bacteria from a reservoir (plant, animal, human, etc.) to a host.
• pathogens can be transmitted either mechanically (for example trachoma by non-stinging flies) to a host, or by injection (for example malaria parasites by mosquitoes) into a host.
• Anopheles malaria, filariasis
• Flies sleeping sickness (trypanosomiasis); cholera, other bacterial diseases;
• Mites acariosis, epidemic typhus, rickettsialpox, tularaemia, Saint Louis encephalitis, tick-borne encephalitis (TBE), Crimean-Congo haemorrhagic fever, borreliosis;
• Ticks borellioses such as Borrelia burgdorferi sensu lato., Borrelia duttoni, tick-borne encephalitis, Q fever (Coxiella burnetii), babesioses (Babesia canis canis), ehrlichiosis.
• vectors in the sense of the present invention are insects, for example aphids, flies, leafhoppers or thrips, which are capable of transmitting plant viruses to plants.
• Other vectors capable of transmitting plant viruses are spider mites, lice, beetles and nematodes.
• vectors in the sense of the present invention are insects and arachnids such as mosquitoes, in particular of the genera Aedes, Anopheles, for example A. gambiae, A. arabiensis, A. funestus, A. dirus (malaria) and Culex, psychodids such as Phlebotomus, Lutzomyia, lice, fleas, flies, mites and ticks capable of transmitting pathogens to animals and/or humans.
• insects and arachnids such as mosquitoes, in particular of the genera Aedes, Anopheles, for example A. gambiae, A. arabiensis, A. funestus, A. dirus (malaria) and Culex, psychodids such as Phlebotomus, Lutzomyia, lice, fleas, flies, mites and ticks capable of transmitting pathogens to animals and/or humans.
• Active compound combinations according to the invention are suitable for use in the prevention of diseases and/or pathogens transmitted by vectors.
• a further aspect of the present invention is the use of active compound combinations according to the invention for vector control, for example in agriculture, in horticulture, in gardens and in leisure facilities, and also in the protection of materials and stored products. Protection of industrial materials
• the active compound combinations according to the invention are suitable for protecting industrial materials against attack or destruction by insects, for example from the orders Coleoptera, Hymenoptera, Isoptera, Lepidoptera, Psocoptera and Zygentoma or by phytopathogenic fungi.
• Industrial materials in the present context are understood to mean inanimate materials, such as preferably plastics, adhesives, sizes, papers and cards, leather, wood, processed wood products and coating compositions.
• plastics such as preferably plastics, adhesives, sizes, papers and cards, leather, wood, processed wood products and coating compositions.
• the use of the invention for protecting wood is particularly preferred.
• the active compound combinations according to the invention are used together with at least one further insecticide and/or one fungicide.
• the active compound combinations according to the invention are present as a ready-to-use pesticide, i.e. they can be applied to the material in question without further modifications.
• Suitable further insecticides or fungicides are in particular those mentioned above.
• the active compound combinations according to the invention can be employed for protecting objects which come into contact with saltwater or brackish water, in particular hulls, screens, nets, buildings, moorings and signalling systems, against fouling.
• the active compound combinations according to the invention alone or in combinations with other active compounds, can be used as antifouling agents.
• the plants listed can be treated particularly advantageously according to the invention with the active compound combinations according to the invention.
• the preferred ranges given above in the active compound combinations also apply to the treatment of these plants. Particular emphasis is placed on the plant treatment with the active compound combinations specifically mentioned in the present text.

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Abstract

Description

Active compound combinations having fungicidal/insecticidal/acaricidal properties

The present invention relates to active compound combinations comprising firstly the compound of formula (I) as shown below and secondly at least one active compound of group (II) selected from Fungicide Groups (1) to (15). Such combinations are highly suitable for controlling animal and microbial pests, such as unwanted insects, arachnids, especially acarids (mites), nematodes as well as for controlling unwanted microorganism and as plant strengthening agents.

The compound of the formula (I) and methods for its production are known from WO 2020/002082 and its use for controlling animal pests has been described. However, the acaricidal and/or insecticidal efficacy and/or the activity spectrum and/or the compatibility of this compound with plants, especially with respect to crop plants, is not always satisfactory. Therefore, novel active compound combinations with improved properties are in great demand.

It has now been found that an active compound combination comprising the compound of the formula (I)

and at least one active compound of group (II) which is selected from

Fungicide Groups (1) to (15) is highly suitable for the control of animal and microbial pests as well as for the control of unwanted microorganism and as plant strengthening agents. Especially, such active compound combinations have very good fungicidal, insecticidal, acaricidal and/or nematicidal properties.

Such active compound combinations are very suitable for controlling animal and microbial pests such as insects and/or arachnids, especially acarids, and/or nematodes, as well as for controlling unwanted microorganism, and indirectly improve plant health. Further, such active compound combinations can be used for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by such pests, e.g. insects, mites and phytopathogens. Further, such active compound combinations are suitable as plant strengthening agents.

For some active compound combinations according to the invention the insecticidal effect and/or arachnicidal/acaricidal effect and/or nematicidal effect and/or antimicrobial effect and/or fungicidal effect and/or the plant-strengthening effect and/or the yield-increasing effect is substantially higher than the sum of the effects of the individual active ingredients. For such active compound combinations a synergistic effect will be present.

Group (II) consists of

Fungicidal Groups (1) to (15).

These groups are further defined as follows:

Fungicidal Group:

(1) inhibitors of the ergosterol biosynthesis selected from the group consisting of (1.001) cyproconazole, (1.002) difenoconazole, (1.003) epoxiconazole, (1.004) fenbuconazole, (1.005) fenhexamid, (1.006) fenpropidin, (1.007) fenpropimorph, (1.008) fenpyrazamine, (1.009) Fluoxytioconazole, (1.010) fluquinconazole, (1.011) flutriafol, (1.012) hexaconazole, (1.013) imazalil, (1.014) imazalil sulfate, (1.015) ipconazole, (1.016) ipfentrifluconazole, (1.017) mefentrifluconazole, (1.018) metconazole, (1.019) myclobutanil, (1.020) paclobutrazol, (1.021) penconazole, (1.022) prochloraz, (1.023) propiconazole, (1.024) prothioconazole, (1.025) pyrisoxazole, (1.026) spiroxamine, (1.027) tebuconazole, ( 1.028) tetraconazole, (1.029) triadimenol, (1.030) tridemorph, (1.031) triticonazole, (1.032) 4-[[6-[(2R)-2-(2,4- difluorophenyl)- 1 , 1 -difluoro-2-hydroxy-3-(5-thioxo-4H- 1 ,2,4-triazol- 1 -yl)propyl] -3-pyridyl]oxy]benzo- nitrile, ( 1.033) 4- [[6- [(2S)-2-(2,4-difluorophenyl)- 1 , 1 -difluoro-2-hydroxy-3-(5-thioxo-4H- 1 ,2,4-triazol- 1 - yl)propyl]-3-pyridyl]oxy]benzonitrile, (1.034) (2R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-l- ( 1 H- 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.035) (2S)-2- [4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl] - 1 -( 1H- 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.036) 1 -( { (2R,4S)-2- [2-chloro-4-(4-chlorophenoxy)phenyl] -4-methyl- 1,3- dioxolan-2-yl Jmethyl)- 1 H- 1 ,2,4-triazole, ( 1.037) 1 -( { (2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl] -4- methyl- 1 ,3-dioxolan-2-yl } methyl)- 1H- 1 ,2,4-triazole, ( 1.038) 2- [6-(4-bromophenoxy)-2-(trifluoromethyl)- 3 -pyridyl] - 1 -( 1 ,2,4-triazol- 1 -yl)propan-2-ol, (1.039) 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3- pyridyl] - 1 -( 1 ,2,4-triazol- 1 -yl)propan-2-ol, (1.040) 3-[2-(l-chlorocyclopropyl)-3-(3-chloro-2-fluoro- phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile, (1.041) methyl 2-[2-chloro-4-(4- chlorophenoxy )phenyl] -2-hydroxy-3-( 1H- 1 ,2,4-triazol- 1 -yl)propanoate, ( 1.042) methyl (2R)-2-[2-chloro- 4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(l,2,4-triazol-l-yl)propanoate, (1.043) methyl (S)-2-[2-chloro-4- (4-chlorophenoxy)phenyl] -2-hydroxy-3-( 1 ,2,4-triazol- 1 -yl)propanoate, (1.044) N'-(2,5-dimethyl-4-(2- methylbenzyl)phenyl)-N-ethyl-N-methylformimidamide, (1.045) N'-(2-chloro-4-(4-cyanobenzyl)-5- methylphenyl)-N-ethyl-N-methylformimidamide, (1.046) N'-(2-chloro-4-(4-methoxybenzyl)-5- methylphenyl)-N-ethyl-N-methylformimidamide, (1.047) N'-(2-chloro-5-methyl-4-phenoxyphenyl)-N- ethyl-N-methylimidoformamide, (1.048) N'-(4-benzyl-2-chloro-5-methylphenyl)-N-ethyl-N- methylformimidamide, (1.049) N'-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N- methylimidoformamide, (1.050) N'-[5-bromo-6-(2,3-dihydro-lH-inden-2-yloxy)-2-methylpyridin-3-yl]-N- ethyl-N -methylimidoformamide, (1.051) N'-{4-[(4,5 -dichloro- 1 ,3-thiazol-2-yl)oxy] -2,5 -dimethylphenyl } - N-ethyl-N-methylimidoformamide, (1.052) N'-{5-bromo-2-methyl-6-[(l-propoxypropan-2-yl)oxy]pyridin- 3-yl}-N-ethyl-N-methylimidoformamide, (1.053) N'-{5-bromo-6-[(lR)-l-(3,5-difluorophenyl)ethoxy]-2- methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.054) N'-{5-bromo-6-[(lS)-l-(3,5-difluoro- phenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.055) N'-{5-bromo-6-[(cis-4- isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.056) N'-{5-bromo- 6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.057) N'-{5-bromo-6-[l-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.058) N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-l-hydroxy-l-phenylethyl)phenyl]-N- methylimidoformamide, (1.059) p-tolylmethyl 4-[(E)-[ethyl(methyl)amino]methyleneamino]-2,5-dimethyl- benzoate and (1.060) N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine;

(2) inhibitors of the respiratory chain at complex I or II selected from the group consisting of (2.001) benzovindiflupyr, (2.002) bixafen, (2.003) boscalid, (2.004) carboxin, (2.005) cyclobutrifluram, (2.006) flubeneteram, (2.007) fluindapyr, (2.008) fluopyram, (2.009) flutolanil, (2.010) fluxapyroxad, (2.011) furametpyr, (2.012) inpyrfluxam, (2.013) Isofetamid, (2.014) isoflucypram, (2.015) isopyrazam, (2.016) penflufen, (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.019) pyrapropoyne, (2.020) pyraziflumid, (2.021) sedaxane, (2.022) Thifluzamide (aka trifluzamide), (2.023) 5,8-difluoro-N-[2-(2-fluoro-4-{[4- (trifluoromethyl)pyridin-2-yl]oxy}phenyl)ethyl]quinazolin-4-amine, (2.024) 5-chloro-N-[2-[l-(4-chloro- phenyl)pyrazol-3-yl] oxy ethyl] -6-ethyl-pyrimidin-4-amine, (2.025) N- [2- [ 1 -(4-chlorophenyl)pyrazol-3- yl]oxyethyl]quinazolin-4-amine, (2.026) l-methyl-3-(trifluoromethyl)-N-[2'-(trifluoromethyl)biphenyl-2- yl] - 1 H-pyrazole-4-carboxamide, (2.027) 2-fluoro-6-(trifluoromethyl)-N-( 1 , 1 ,3-trimethyl-2,3-dihydro- 1 H- inden-4-yl)benzamide, (2.028) 3-(difluoromethyl)-l-methyl-N-(l,l,3-trimethyl-2,3-dihydro-lH-inden-4- yl)-lH-pyrazole-4-carboxamide, (2.029) 3-(difluoromethyl)-l-methyl-N-[(3S)-l,l,3-trimethyl-2,3-dihydro- lH-inden-4-yl]-lH-pyrazole-4-carboxamide, (2.030) 3-(difluoromethyl)-N-[(3R)-7-fluoro-l,l,3-trimethyl-

2.3-dihydro-lH-inden-4-yl]-l-methyl-lH-pyrazole-4-carboxamide, (2.031) 3-(difluoromethyl)-N-[(3S)-7- fluoro-l,l,3-trimethyl-2,3-dihydro-lH-inden-4-yl]-l-methyl-lH-pyrazole-4-carboxamide, (2.032) N- [( 1 R,4S)-9-(dichloromethylene)- 1 ,2,3,4-tetrahydro- 1 ,4-methanonaphthalen-5-yl] -3-(difluoromethyl)- 1 - methyl-lH-pyrazole-4-carboxamide, (2.033) N-[(lS,4R)-9-(dichloromethylene)-l,2,3,4-tetrahydro-l,4- methanonaphthalen-5-yl]-3-(difluoromethyl)-l-methyl-lH-pyrazole-4-carboxamide, (2.034) N-[l-(2,4- dichlorophenyl)- 1 -methoxypropan-2-yl] -3-(difluoromethyl)- 1 -methyl- 1 H-pyrazole-4-carboxamide, (2.035) 5-chloro-l,3-dimethyl-N-[(3S)-l,l,3-trimethyl-3H-isobenzofuran-4-yl]pyrazole-4-carboxamide, (2.036) 5- chloro-l,3-dimethyl-N-[(3R)-l,l,3-trimethyl-3H-isobenzofuran-4-yl]pyrazole-4-carboxamide, (2.037) N- [2-[(lS)-l,3-dimethylbutyl]phenyl]-5-fluoro-l,3-dimethyl-pyrazole-4-carboxamide, (2.038) N-[2-[(lR)-

1.3-dimethylbutyl]phenyl]-5-fluoro-l,3-dimethyl-pyrazole-4-carboxamide, (2.039) 3-(difluoromethyl)-N- methoxy-l-methyl-N-[(lS)-l-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide, (2.040) 3- (difluoromethyl)-N-methoxy-l-methyl-N-[(lR)-l-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4- carboxamide, (2.041) N- [2- [( 1 S)- 1 ,3-dimethylbutyl] -3-thienyl] - 1 -methyl-3-(trifluoromethyl)pyrazole-4- carboxamide, (2.042) N-[2-[(lR)-l ,3-dimethylbutyl] -3 -thienyl] - 1 -methyl-3 -(trifluoromethyl)pyrazole-4- carboxamide, (2.043) N-[rac-(lS,2S)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide and (2.044) 2-(difluoromethyl)-N-(3-ethyl-l,l-dimethyl-indan-4-yl)pyridine-3-carboxamide;

(3) inhibitors of the respiratory chain at complex III selected from the group consisting of (3.001) ametoctradin, (3.002) amisulbrom, (3.003) azoxystrobin, (3.004) coumethoxystrobin, (3.005) coumoxystrobin, (3.006) cyazofamid, (3.007) dimoxystrobin, (3.008) enoxastrobin, (3.009) famoxadone, (3.010) fenamidone, (3.011) fenpicoxamid, (3.012) florylpicoxamid, (3.013) flufenoxystrobin, (3.014) fluoxastrobin, (3.015) kresoxim-methyl, (3.016) mandestrobin, (3.017) metarylpicoxamid, (3.018) metominostrobin, (3.019) metyltetraprole, (3.020) orysastrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3.023) pyrametostrobin, (3.024) pyraoxystrobin, (3.025) pyribencarb, (3.026) trifloxystrobin, (3.027) (2E)-2-{2-[({ [( 1 E)- 1 -(3- { [(E)-l-fluoro-2-phenylvinyl]oxy }phenyl)ethylidene]- amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide, (3.028) (2E,3Z)-5-{ [l-(4-chloro-2- fluorophenyl)-lH-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.029) (2E,3Z)-5- {[l-(4-chlorophenyl)-lH-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.030) (2R)- 2- { 2- [(2,5 -dimethylphenoxy)methyl]phenyl } -2-methoxy-N -methylacetamide, (3.031 ) (2S)-2- { 2- [(2,5 - dimethylphenoxy )methyl]phenyl}-2-methoxy-N-methylacetamide, (3.032) (Z,2E)-5-[l-(2,4- dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide, (3.033) methyl (Z)-2-(5- cyclohexyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate, (3.034) methyl (Z)-2-(5-cyclopentyl-2-methyl- phenoxy)-3-methoxy-prop-2-enoate, (3.035) methyl (Z)-3-methoxy-2-[2-methyl-5-(3-propylpyrazol-l- yl)phenoxy]prop-2-enoate, (3.036) methyl (Z)-3-methoxy-2-[2-methyl-5-[3-(trifluoromethyl)pyrazol-l- yl]phenoxy]prop-2-enoate, (3.037) methyl { 5- [3-(2,4-dimethylphenyl)- IH-pyrazol- 1 -yl] -2-methylbenzyl } - carbamate, (3.038) (2E)-2-methoxyimino-N-methyl-2- [3-methyl-2- [[(E)- 1 - [3-(trifluoromethyl)phenyl] - ethylideneamino]oxymethyl]phenyl] acetamide, (3.039) (2E)-2- [2- [[(E)- 1 -(3 ,5-difluorophenyl)ethylidene- amino]oxymethyl]-3-methyl-phenyl]-2-methoxyimino-N-methyl-acetamide, (3.040) [rac-2-(4-bromo-7- fluoro-indol- 1 -yl)- 1 -methyl-propyl] (2S)-2- [(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino] - propanoate, (3.041) [rac-2-(7-bromo-4-fluoro-indol- 1 -yl)- 1 -methyl-propyl] (2S)-2- [(3-acetoxy-4-methoxy- pyridine-2-carbonyl)amino]propanoate, (3.042) [rac-2-(7-bromoindol-l-yl)-l-methyl-propyl] (2S)-2-[(3- hydroxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.043) [rac-2-(3 ,5-dichloro-2-pyridyl)- 1 - methyl-propyl] (2S)-2-[(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.044) [( 1 S) - 1 - [ 1 - (l-naphthyl)cyclopropyl]ethyl] (2S)-2-[(3-acetoxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.045) [( 1 S)- 1 -[ 1 -( 1 -naphthyl)cyclopropyl] ethyl] (2S)-2- [(3-hydroxy-4-methoxy-pyridine-2-carbonyl)- amino]propanoate, (3.046) [( 1 S)- 1 -[ 1 -( 1 -naphthyl)cyclopropyl]ethyl] (2S)-2-[[3-(acetoxymethoxy)-4- methoxy-pyridine-2-carbonyl] amino]propanoate, (3.047) [2- [ [( 1 S)-2-[( 1 RS,2SR)-2-(3 ,5-dichloro-2- pyridyl)-l-methyl-propoxy]-l-methyl-2-oxo-ethyl]carbamoyl]-4-methoxy-3-pyridyl]oxymethyl 2-methyl- propanoate, (3.048) 2-[cyano-(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl- thiazole-4-carboxamide, (3.049) 2-[cyano-(2,6-difluoro-4-pyridyl)amino]-5-methyl-N-spiro[3.4]octan-3- yl-thiazole-4-carboxamide, (3.050) 2-[cyano-(2,6-difluoro-4-pyridyl)amino]-N-hexyl-5-methyl-thiazole-4- carboxamide, (3.051) 2-[acetyl-(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl- thiazole-4-carboxamide, (3.052) 2-[(2,6-difluoro-4-pyridyl)-(2-methylpropanoyl)amino]-N-(2,2- dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide, (3.053) 2-[(2,6-difluoro-4-pyridyl)-(2-methoxy- acetyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide and (3.054) N-(3-ethyl-3,5,5- trimethylcyclohexyl)-3-formamido-2-hydroxybenzamide;

(4) inhibitors of the mitosis and cell division selected from the group consisting of (4.001) carbendazim, (4.002) diethofencarb, (4.003) ethaboxam, (4.004) fluopicolide, (4.005) fluopimomide, (4.006) metrafenone, (4.007) pencycuron, (4.008) pyridachlometyl, (4.009) pyriofenone (chlazafenone), (4.010) thiabendazole, (4.011) thiophanate-methyl, (4.012) zoxamide, (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)- 6-methylpyridazine, (4.014) 3-chloro-5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluoro- phenyl)pyridazine, (4.015) 4-(2-bromo-4-fluorophenyl)-N-(2,6-difluorophenyl)-l,3-dimethyl-lH-pyrazol- 5-amine, (4.016) 4-(2-bromo-4-fluorophenyl)-N-(2-bromo-6-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5- amine, (4.017) 4-(2-bromo-4-fluorophenyl)-N-(2-bromophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.018)

4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.019) 4-(2- bromo-4-fluorophenyl)-N-(2-chlorophenyl)-l ,3-dimethyl-lH-pyrazol-5-amine, (4.020) 4-(2-bromo-4- fluorophenyl)-N-(2-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.021) 4-(2-chloro-4-fluorophenyl)- N-(2,6-difluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.022) 4-(2-chloro-4-fluorophenyl)-N-(2- chloro-6-fluorophenyl)- 1 ,3-dimethyl- 1 H-pyrazol-5-amine, (4.023) 4-(2-chloro-4-fluorophenyl)-N-(2- chlorophenyl)- 1 ,3-dimethyl- 1 H-pyrazol-5-amine, (4.024) 4-(2-chloro-4-fluorophenyl)-N-(2-fluorophenyl)- l,3-dimethyl-lH-pyrazol-5-amine, (4.025) 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)-3,6- dimethylpyridazine, (4.026) N-(2-bromo-6-fluorophenyl)-4-(2-chloro-4-fluorophenyl)- 1 ,3-dimethyl- 1 H- pyrazol-5-amine, (4.027) N-(2-bromophenyl)-4-(2-chloro-4-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5- amine and (4.028) N-(4-chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)- 1 ,3-dimethyl- IH-pyrazol-

5-amine;

(5) compounds capable to have a multisite action selected from the group consisting of (5.001) bordeaux mixture, (5.002) captafol, (5.003) captan, (5.004) chlorothalonil, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(2+) sulfate, (5.010) dithianon, (5.011) dodine, (5.012) folpet, (5.013) mancozeb, (5.014) maneb, (5.015) metiram, (5.016) metiram zinc, (5.017) oxine-copper, (5.018) propineb, (5.019) sulfur and sulfur preparations including calcium polysulfide, (5.020) thiram, (5.021) zineb, (5.022) ziram and (5.023) 6-ethyl-5,7-dioxo-6,7-dihydro- 5H-pyrrolo[3',4':5,6] [1 ,4]dithiino[2,3-c] [1 ,2]thiazole-3-carbonitrile;

(6) compounds capable to induce a host defence selected from the group consisting of (6.001) acibenzolar- S-methyl, (6.002) fosetyl-aluminium, (6.003) fosetyl-calcium, (6.004) fosetyl-sodium, (6.005) isotianil, (6.006) phosphorous acid and its salts, (6.007) probenazole and (6.008) tiadinil;

(7) inhibitors of the amino acid and/or protein biosynthesis selected from the group consisting of (7.001) cyprodinil, (7.002) kasugamycin, (7.003) kasugamycin hydrochloride hydrate, (7.004) oxytetracycline and (7.005) pyrimethanil; (8) inhibitors of the ATP production: (8.001) silthiofam;

(9) inhibitors of the cell wall synthesis selected from the group consisting of (9.001) benthiavalicarb, (9.002) dimethomorph, (9.003) flumorph, (9.004) iprovalicarb, (9.005) mandipropamid, (9.006) pyrimorph, (9.007) valifenalate, (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-l-(morpholin-4-yl)prop-2-en-l- one and (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-l-(morpholin-4-yl)prop-2-en-l-one;

(10) inhibitors of the lipid synthesis or transport, or membrane synthesis selected from the group consisting of (10.001) fluoxapiprolin, (10.002) natamycin, (10.003) oxathiapiprolin, (10.004) propamocarb, (10.005) propamocarb hydrochloride, (10.006) propamocarb-fosetylate, (10.007) tolclofos-methyl, (10.008) l-(4-{4- [(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-l,2-oxazol-3-yl]-l,3-thiazol-2-yl}piperidin-l-yl)-2-[5-methyl-3- (trifluoromethyl)- 1 H-pyrazol- 1 -yl]ethanone, (10.009) 1 -(4- { 4- [(5S)-5-(2,6-difluorophenyl)-4,5-dihydro- 1 ,2-oxazol-3-yl]- 1 ,3-thiazol-2-yl}piperidin- l-yl)-2-[5-methyl-3-(trifluoromethyl)- IH-pyrazol- 1 - yl]ethanone, (10.010) 2-[3,5-bis(difluoromethyl)-lH-pyrazol-l-yl]-l-[4-(4-{5-[2-(prop-2-yn-l-yloxy)- phenyl]-4,5-dihydro-l,2-oxazol-3-yl}-l,3-thiazol-2-yl)piperidin-l-yl]ethanone, (10.011) 2-[3,5- bis(difluoromethyl)- 1 H-pyrazol- 1 -yl] - 1 - [4-(4- { 5 - [2-chloro-6-(prop-2-yn- 1 -yloxy)phenyl] -4,5 -dihydro- 1,2- oxazol-3-yl}-l,3-thiazol-2-yl)piperidin-l-yl]ethanone, (10.012) 2-[3,5-bis(difluoromethyl)-lH-pyrazol-l- yl] - 1 - [4-(4- { 5 - [2-fluoro-6-(prop-2-yn- 1 -yloxy)phenyl] -4,5 -dihydro- 1 ,2-oxazol-3 -yl } - 1 ,3 -thiazol-2- yl)piperidin-l-yl]ethanone, (10.013) 2-{(5R)-3-[2-(l-{ [3,5-bis(difluoromethyl)-lH-pyrazol-l- yl]acetyl}piperidin-4-yl)-l,3-thiazol-4-yl]-4,5-dihydro-l,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.014) 2-{(5S)-3-[2-(l-{[3,5-bis(difluoromethyl)-lH-pyrazol-l-yl]acetyl}piperidin-4-yl)-l,3-thiazol-4- yl]-4,5-dihydro-l,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.015) 2-{3-[2-(l-{ [3,5- bis(difluoromethyl)- IH-pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol-4-yl] -4,5-dihydro- 1 ,2-oxazol-5- yljphenyl methanesulfonate, (10.016) 3-[2-(l-{[5-methyl-3-(trifluoromethyl)-lH-pyrazol-l- yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol-4-yl] - 1 ,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, ( 10.017) 9-fluoro-3 - [2-( 1 - { [5 -methyl-3 -(trifluoromethyl)- 1 H-pyrazol- 1 -yl] acetyl } piperidin-4-yl)- 1 ,3 -thiazol-4-yl] - 1,5 -dihydro-2, 4-benzodioxepin-6-yl methanesulfonate, (10.018) 3- [2-( 1 -{ [3,5-bis(difluoromethyl)-lH- pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol-4-yl] - 1 ,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate and ( 10.019) 3- [2-( 1 - { [3 ,5-bis(difluoromethyl)- IH-pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3- thiazol-4-yl]-9-fluoro-l,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate;

(11) inhibitors of the melanin biosynthesis selected from the group consisting of (11.001) tolprocarb and (11.002) tricyclazole;

(12) inhibitors of the nucleic acid synthesis selected from the group consisting of (12.001) benalaxyl, (12.002) benalaxyl-M (kiralaxyl), (12.003) metalaxyl and (12.004) metalaxyl-M (mefenoxam);

(13) inhibitors of the signal transduction selected from the group consisting of (13.001) fludioxonil, (13.002) iprodione, (13.003) procymidone, (13.004) proquinazid, (13.005) quinoxyfen and (13.006) vinclozolin; (14) compounds capable to act as an uncoupler selected from the group consisting of (14.001) fluazinam and

(14.002) meptyldinocap; and

(15) further compounds selected from the group consisting of (15.001) abscisic acid, (15.002) aminopyrifen, (15.003) benthiazole, (15.004) bethoxazin, (15.005) capsimycin, (15.006) carvone, (15.007) chinomethionat, (15.008) chloroinconazide, (15.009) cufraneb, (15.010) cyflufenamid, (15.011) cymoxanil, (15.012) cyprosulfamide, (15.013) dipymetitrone, (15.014) D-tagatose, (15.015) flufenoxadiazam, (15.016) flumetylsulforim, (15.017) flutianil, (15.018) ipflufenoquin, (15.019) methyl isothiocyanate, (15.020) mildiomycin, (15.021) nickel dimethyldithiocarbamate, (15.022) nitrothal-isopropyl, (15.023) oxyfenthiin, (15.024) pentachlorophenol and salts, (15.025) picarbutrazox, (15.026) quinofumelin, (15.027) tebufloquin, (15.028) tecloftalam, (15.029) tolnifanide, (15.030) 2-(6-benzylpyridin-2-yl)quinazoline, (15.031) 2-[6-(3- fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline, (15.032) 2-phenylphenol and salts, (15.033) 4- amino-5-fluoropyrimidin-2-ol (tautomeric form: 4-amino-5-fluoropyrimidin-2(lH)-one), (15.034) 4-oxo-4- [(2-phenylethyl)amino]butanoic acid, (15.035) 5-amino-l,3,4-thiadiazole-2-thiol, (15.036) 5-chloro-N'- phenyl-N'-(prop-2-yn- 1 -yl)thiophene-2-sulfonohydrazide, ( 15.037) 5-fluoro-2- [(4- fluorobenzyl)oxy]pyrimidin-4-amine, (15.038) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidin-4-amine, (15.039) but-3-yn-l-yl {6-[({[(Z)-(l-methyl-lH-tetrazol-5- yl)(phenyl)methylene]amino}oxy)methyl]pyridin-2-yl}carbamate, (15.040) ethyl (2Z)-3-amino-2-cyano-3- phenylacrylate, (15.041) methyl 2-[acetyl-[2-ethylsulfonyl-4-(trifluoromethyl)benzoyl]amino]-5- (trifluoromethoxy)benzoate, ( 15.042) N -acetyl-N - [2-bromo-4-(trifluoromethoxy)phenyl] -2-ethylsulfonyl- 4-(trifluoromethyl)benzamide, (15.043) phenazine- 1 -carboxylic acid, (15.044) propyl 3,4,5- trihydroxybenzoate, (15.045) quinolin-8-ol, (15.046) quinolin-8-ol sulfate (2:1), (15.047) (2R)-2-benzyl-N- (8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.048) (2S)-2-benzyl-N-(8-fluoro-2-methyl- 3-quinolyl)-2,4-dimethyl-pentanamide, ( 15.049) 1 -(4,5-dimethyl- IH-benzimidazol- 1 -yl)-4,4-difluoro-3 ,3- dimethyl-3,4-dihydroisoquinoline, (15.050) l-(4,5-dimethylbenzimidazol-l-yl)-4,4,5-trifluoro-3,3- dimethyl-isoquinoline, (15.051) l-(5-(fluoromethyl)-6-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4- dihydroisoquinoline, (15.052) l-(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4- dihydroisoquinoline, (15.053) l-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl- 3,4-dihydroisoquinoline, (15.054) l-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl- 3,4-dihydroisoquinoline, (15.055) 4,4-difluoro-3,3-dimethyl-l-(7-methylpyrazolo[l,5-a]pyridin-3-yl)- isoquinoline, (15.056) l-(6,7-dimethylpyrazolo[l,5-a]pyridin-3-yl)-4,4,5-trifluoro-3,3-dimethyl- isoquinoline, (15.057) l-(6,7-dimethylpyrazolo[l,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4- dihydroisoquinoline, ( 15.058) 2- { 2-fluoro-6- [(8-fluoro-2-methylquinolin-3-yl)oxy]phenyl }propan-2-ol, (15.059) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-l-yl)quinoline, (15.060) 3-(4,4-difluoro- 3,3-dimethyl-3,4-dihydroisoquinolin-l-yl)-8-fluoroquinoline, (15.061) 3-(4,4-difluoro-5,5-dimethyl-4,5- dihydrothieno[2,3-c]pyridin-7-yl)quinoline, (15.062) 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydro- isoquinolin- 1 -yl)quinoline, ( 15.063) 4,4-difluoro-3 ,3-dimethyl- 1 -(4-methylbenzimidazol- 1 -yl)isoquinoline, ( 15.064) 4, 4-difluoro-3 ,3-dimethyl- 1 -(6-methylpyrazolo[ 1 ,5-a]pyridin-3-yl)isoquinoline, ( 15.065) 5- bromo-l-(5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.066) 7,8-difluoro-N-[rac-l- benzyl-l,3-dimethyl-butyl]quinoline-3-carboxamide, (15.067) 8-fluoro-3-(5-fluoro-3,3,4,4-tetramethyl-3,4- dihydroisoquinolin-l-yl)-quinoline, (15.068) 8-fluoro-3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-l- yl)-quinoline, (15.069) 8-fluoro-N-(4,4,4-trifluoro-2-methyl-l-phenylbutan-2-yl)quinoline-3-carboxamide, (15.070) 8-fluoro-N-[(lR)-l-[(3-fluorophenyl)methyl]-l,3-dimethyl-butyl]quinoline-3-carboxamide,

(15.071) 8-fluoro-N-[(lS)-l-[(3-fluorophenyl)methyl]-l,3-dimethyl-butyl]quinoline-3-carboxamide,

(15.072) 8-fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-l-phenylbutan-2-yl]quinoline-3-carboxamide, (15.073) 8-fluoro-N-[rac-l-[(3-fluorophenyl)methyl]-l,3-dimethyl-butyl]quinoline-3-carboxamide, (15.074) 9- fluoro-2,2-dimethyl-5-(quinolin-3-yl)-2,3-dihydro-l,4-benzoxazepine, (15.075) N-(2,4-dimethyl-l- phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.076) N-[(lR)-l-benzyl-l,3-dimethyl-butyl]-7,8- difluoro-quinoline-3-carboxamide, (15.077) N-[(lS)-l-benzyl-l,3-dimethyl-butyl]-7,8-difluoro-quinoline-

3-carboxamide, (15.078) N-[(2R)-2,4-dimethyl-l-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.079) rac-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.080) (5RS)-3-[3- (3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2,4-dimethylbenzyl)-5,6-dihydro-4H-l,2,4- oxadiazine, (15.081) (5S)-3-[3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2,4- dimethylbenzyl)-5,6-dihydro-4H-l,2,4-oxadiazine, (15.082) (5RS)-5-(4-bromo-2-methylbenzyl)-3-[3-(3- chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5,6-dihydro-4H-l,2,4-oxadiazine, (15.083) (5RS)-3-[3- (3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-l,2,4- oxadiazine, (15.084) (5S)-5-(4-bromo-2-methylbenzyl)-3-[3-(3-chloro-2-fluorophenoxy)-6- methylpyridazin-4-yl]-5,6-dihydro-4H-l,2,4-oxadiazine, (15.085) (5R)-3-[3-(3-chloro-2-fluorophenoxy)-6- methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-l,2,4-oxadiazine, (15.086) (5S)-3-[3- (3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-l,2,4- oxadiazine, (15.087) 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[2-(2,4-dimethylphenyl)-2,2- difluoroethyl]-5-methylpyridazine-4-carboxamide, (15.088) 3-(3-bromo-2-fluoro-phenoxy)-6-chloro-N-[2- (2-chloro-4-methylphenyl)-2,2-difluoroethyl]-5-methylpyridazine-4-carbox-amide, (15.089) 6-chloro-N- [2-(2-chloro-4-methylphenyl)-2,2-difluoroethyl]-3-(3-cyclopropyl-2-fluoro-phenoxy)-5-methylpyridazine-

4-carboxamide, ( 15.090) 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N- [2-(3 ,4-dimethylphenyl)-2,2- difluoroethyl]-5-methylpyridazine-4-carboxamide, (15.091) 6-chloro-3-(3-chloro-2-fluorophenoxy)-N-[2- (2,4-dimethylphenyl)-2,2-difluoroethyl] -5-methylpyridazine-4-carbox-amide, ( 15.092) N- [2-(2-bromo-4- methylphenyl)-2,2-difluoroethyl]-6-chloro-3-(3-cyclopropyl-2-fluoro-phenoxy)-5-methylpyridazine-4- carboxamide, (15.093) l,l-diethyl-3-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.094) l,3-dimethoxy-l-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.095) 1- [[3-fluoro-4-(5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl)phenyl]methyl]azepan-2-one, (15.096) l-[[4-[5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.097) 1 -methoxy- l-methyl-3- [[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.098) l-methoxy-3-methyl-l-[[4-[5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.099) 2-(difluoromethyl)-5-[2-[l-(2,6- difluorophenyl)cyclopropoxy]pyrimidin-5 -yl] - 1 ,3 ,4-oxadiazole, (15.100) 2,2-difluoro-N -methyl-2- [4- [5 - (trifluoromethyl)- 1, 2, 4-oxadiazol-3-yl]phenyl] acetamide, (15.101) 3,3-dimethyl-l-[[4-[5-(trifluoromethyl)- 1.2.4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.102) 3-ethyl-l-methoxy-l-[[4-[5-

(trifluoromethyl)- 1 ,2,4-oxadiazol-3-yl]phenyl]methyl]urea, ( 15.103) 4,4-dimethyl- 1 - [[4- [5-

(trifluoromethyl)-l ,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.104) 4,4-dimethyl-2-[[4-[5- (trifluoromethyl)-l ,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.105) 4-[5-(trifluoromethyl)-

1.2.4-oxadiazol-3-yl]phenyl dimethylcarbamate, (15.106) 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-l,2,4- oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.107) 5-[5-(difluoromethyl)-l ,3,4-oxadiazol-2-yl]-N- [(lR)-l-(2,6-difluorophenyl)ethyl]pyrimidin-2-amine, (15.108) 5-[5-(difluoromethyl)-l,3,4-oxadiazol-2- yl]-N-[(lR)-l-(2,6-difluorophenyl)propyl]pyrimidin-2-amine, (15.109) 5-[5-(difluoromethyl)-l,3,4- oxadiazol-2-yl] -N- [( 1R)- 1 -(2-fluorophenyl)ethyl]pyrimidin-2-amine, (15.110) 5- [5-(difluoromethyl)- 1,3,4- oxadiazol-2-yl] -N- [( 1R)- 1 -(2-fluorophenyl)ethyl]pyrimidin-2-amine, (15.111) 5- [5-(difluoromethyl)- 1,3,4- oxadiazol-2-yl]-N-[(lR)-l-(3,5-difluorophenyl)ethyl]pyrimidin-2-amine, (15.112) 5-[5-(difluoromethyl)-

1.3.4-oxadiazol-2-yl]-N-[(lR)-l-phenylethyl]pyrimidin-2-amine, (15.113) 5-[5-(difluoromethyl)-l,3,4- oxadiazol-2-yl] -N- [ 1 -(2-fluorophenyl)cyclopropyl]pyrimidin-2- amine, (15.114) 5 -methyl- 1 - [ [4- [5 -

(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.115) ethyl l-{4-[5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzyl}-lH-pyrazole-4-carboxylate, (15.116) methyl {4-[5- (trifluoromethyl)- 1 ,2,4-oxadiazol-3-yl]phenyl } carbamate, (15.117) N-( 1 -methylcyclopropyl)-4- [5-

(trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzamide, (15.118) N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-

1.2.4-oxadiazol-3-yl]benzamide, (15.119) N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl]methyl]propanamide, (15.120) N,N-dimethyl-l-{4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]benzyl } - 1H- 1 ,2,4-triazol-3-amine, (15.121) N- [(E)-methoxyiminomethyl] -4- [5-(trifluoromethyl)- 1 ,2,4- oxadiazol-3-yl]benzamide, (15.122) N-[(E)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)- l,2,4-oxadiazol-3-yl]benzamide, (15.123) N-[(Z)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-l,2,4- oxadiazol-3-yl]benzamide, (15.124) N-[(Z)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)- l,2,4-oxadiazol-3-yl]benzamide, (15.125) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl]methyl]-3,3,3-trifluoro-propanamide, (15.126) N-[[4-[5-(trifluoromethyl)-l ,2,4-oxadiazol-3- yl]phenyl]methyl]propanamide, (15.127) N-[4-[5-(trifluoromethyl)-l ,2,4-oxadiazol-3- yl]phenyl]cyclopropanecarboxamide, (15.128) N-{2,3-difluoro-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]benzyl } butanamide, (15.129) N- { 4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3- yl]benzyl Jcyclopropanecarboxamide, (15.130) N- { 4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3- yl]phenyl}propanamide, (15.131) N-allyl-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]- methyl] acetamide, (15.132) N-allyl-N- [[4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3-yl]phenyl]methyl] - propanamide, (15.133) N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]- methyl]propanamide, (15.134) N-methoxy-N- [[4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3-yl]phenyl] - methyl]cyclopropanecarboxamide, (15.135) N-methyl-4-[5-(trifluoromethyl)-l ,2,4-oxadiazol-3-yl]- benzamide, (15.136) N-methyl-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzenecarbothioamide, (15.137) N-methyl-N-phenyl-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzamide and (15.138) 2,2- difluoro-2-[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]acetic acid. All mixing partners of group (II) can, if their functional groups enable this, optionally form salts with suitable bases or acids. All mixing partners of group (II) can include tautomeric forms, where applicable.

The active compounds of group (II) which are specified herein by their “common name” are known and described inter alia in "The Pesticide Manual", 16th edition, The British Crop Protection Council and the Royal Soc. of Chemistry, 2012 and the literature cited therein or can be searched in the internet (e.g. http://www.alanwood.net/pesticides). Particularly, reference shall be made to said Manual or website in order to further specify such a mixing partner of group (II), e.g. to provide its chemical structure, IUPAC name or its pesticidal activity. Further information about such a mixing partner of group (II) will be provided as well, in particular it's composition in case that the mixing partner of group (II) is itself a mixture, e.g. a mixture of enantiomers.

If, e.g. within this description, the common name of an active compound is used, this in each case encompasses all common derivatives, such as the esters and salts, and isomers, especially optical isomers, especially the commercial form or forms. If an ester or salt is referred to by the common name, this also refers in each case to all other common derivatives, such as other esters and salts, the free acids and neutral compounds, and isomers, especially optical isomers, especially the commercial form or forms. The chemical compound names mentioned refer to at least one of the compounds encompassed by the common name, frequently a preferred compound.

Methods and uses

The invention also relates to methods for controlling animal or microbial pests, in which active compound combinations according to the invention are allowed to act on the animal or microbial pests and/or their habitat. Preferably, the animal pest is an insect or arachnid or acarid pest. Such control of the animal or microbial pests is preferably conducted in agriculture and forestry, and in material protection. Preferably excluded herefrom are methods for the surgical or therapeutic treatment of the human or animal body and diagnostic methods carried out on the human or animal body.

The invention also relates to the use of active compound combinations according to the invention as pesticidal combinations, in particular crop protection agents. In the context of the present application, the term "pesticide" in each case also always comprises the term "crop protection agent".

The active compound combinations according to invention have also potent microbicidal activity and/or plant defense modulating potential. They can be used for controlling unwanted microorganisms, such as unwanted fungi and bacteria, on plants. They can be particularly useful in crop protection (they control microorganisms that cause plants diseases) or for protecting materials (e.g. industrial materials, timber, storage goods). More specifically, the active compound combinations according to the invention can be used to protect seeds, germinating seeds, emerged seedlings, plants, plant parts, fruits, harvest goods and/or the soil in which the plants grow from unwanted microorganisms. Control or controlling as used herein encompasses protective, curative and eradicative treatment of unwanted microorganisms. Unwanted microorganisms may be pathogenic bacteria, pathogenic virus, pathogenic oomycetes or pathogenic fungi, more specifically phytopathogenic bacteria, phytopathogenic virus, phytopathogenic oomycetes or phytopathogenic fungi. These phytopathogenic microorganims are the causal agents of a broad spectrum of plants diseases.

More specifically, the active compound combinations according to the invention can be used as fungicides. For the purpose of the specification, the term “fungicide” refers to a compound or composition (formulation) that can be used in crop protection for the control of unwanted fungi, such as Plasmodiophoromycetes, Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and Deuteromycetes and/or for the control of Oomycetes.

The active compound combinations of the invention may also be used as antibacterial agent. In particular, they may be used in crop protection, for example for the control of unwanted bacteria, such as Pseudomonadaceae, Rhizobiaceae, Xanthomonadaceae, Enterobacteriaceae, Corynebacteriaceae and Streptomycetaceae.

The present invention also relates to a method for controlling unwanted microorganisms, such as unwanted fungi, oomycetes and bacteria, on plants comprising the step of applying the active compound combinations according to the invention to the microorganisms and/or their habitat (to the plants, plant parts, seeds, fruits or to the soil in which the plants grow), wherein the the active compound of formula (I) and active compounds of group (II) may be applied in a simultaneous, separate or sequential manner. If the single compounds are applied in a sequential manner, i.e. at different times, they are applied one after the other within a reasonably short period, such as a few hours or days.

Typically, when the active compound combinations according to the invention are used in curative or protective methods for controlling phytopathogenic fungi and/or phytopathogenic oomycetes, an effective and plant-compatible amount thereof is applied to the plants, plant parts, fruits, seeds or to the soil or substrates in which the plants grow. Suitable substrates that may be used for cultivating plants include inorganic based substrates, such as mineral wool, in particular stone wool, perlite, sand or gravel; organic substrates, such as peat, pine bark or sawdust; and petroleum based substrates such as polymeric foams or plastic beads. Effective and plant-compatible amount means an amount that is sufficient to control or destroy the fungi present or liable to appear on the cropland and that does not entail any appreciable symptom of phytotoxicity for said crops. Such an amount can vary within a wide range depending on the fungus to be controlled, the type of crop, the crop growth stage, the climatic conditions and the respective compound or composition (formulation) of the invention used. This amount can be determined by systematic field trials that are within the capabilities of a person skilled in the art.

The active compound combinations according to the invention are preferably suitable for controlling animal and microbial pests. The active compound combinations according to the invention are particularly preferably suitable for controlling animal pests, especially insect or arachnid or acarid pests.

The active compound combinations according to the invention are particularly preferably suitable for controlling microbial pests.

The active compound combinations according to the invention are particularly preferably suitable for controlling nematodes.

The active compound combinations according to the invention are particularly preferably suitable for controlling unwanted microorganism.

The active compound combinations according to the invention are particularly preferably used as plantstrengthening agents.

If appropriate, the active compound combinations according to the invention can, at certain concentrations or application rates, also be used as herbicides, safeners, growth regulators or agents to improve plant properties, or as microbicides, for example as fungicides, antimycotics, bactericides, viricides (including agents against viroids) or as agents against MLO (Mycoplasma-like organisms) and RLO (Rickettsia-like organisms). If appropriate, they can also be employed as intermediates or precursors for the synthesis of other active compound compositions.

The invention also relates to a process for preparing a crop protection agent, characterized in that an active compound combination according to the invention is mixed with extenders and/or surfactants.

Preferred are active compound combinations comprising the compound of formula (I) and exactly one active compound of group (II).

Mixing ratio

Preferabyl, the active compounds in the active compound combinations according to the invention are present in certain weight ratios. However, the weight ratios of the active compounds in the active compound combinations can be varied within a relatively wide range. In general, the combinations according to the invention comprise an active compound (I) and an active compound of group (II) selected from Fungicide Groups (1) to (15) in the following preferred and more preferred mixing ratios:

Preferred mixing ratio: 125:1 to 1:125 such as 100:1 to 1:100 or 80:1 to 1:80.

More preferred mixing ratio: 40:1 to 1:80 such as 40:1 to 1:5 or 1:5 to 1:80 or even 20:1 to 1:60 or 20:1 to 1:50 or 15:1 to 1:50 or 10:1 to 1:50 or 5:1 to 1:25 or 2.5:1 to 1:10.

The mixing ratios are based on weight ratios. The ratio is to be understood as meaning active compound of the formula (I) : an active compound of group (II). Additional mixing partners

Furthermore, the active compound combinations according to the invention may contain one or more further active substances selected from a fungicide or an insecticide, i.e. at least one further fungicidally or insecticidally active additive. Preferably, such further active additive is selected from the groups mentioned below. The active compounds identified here by their common names are known and are described, for example, in the pesticide handbook (“The Pesticide Manual” 16th Ed., British Crop Protection Council 2012) or can be found on the Internet (e.g. http://www.alanwood.net/pesticides). The classification is based on the current IRAC Mode of Action Classification Scheme at the time of filing of this patent application.

(1) Acetylcholinesterase (AChE) inhibitors, preferably carbamates selected from alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC and xylylcarb, or organophosphates selected from acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos/DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos, isopropyl O-(methoxyaminothiophosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim, pirimiphos-methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, triclorfon and vamidothion.

(2) GABA-gated chloride channel blockers, preferably cyclodiene-organochlorines selected from chlordane and endosulfan, or phenylpyrazoles (fiproles) selected from ethiprole and fipronil.

(3) Sodium channel modulators, preferably pyrethroids selected from acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin s-cyclopentenyl isomer, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin [(IR)-trans-isomer], deltamethrin, empenthrin [(EZ)-(lR)-isomer], esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, imiprothrin, kadethrin, momfluorothrin, permethrin, phenothrin [(IR)-trans-isomer], prallethrin, pyrethrins (pyrethrum), resmethrin, silafluofen, tefluthrin, tetramethrin, tetramethrin [(1R)- isomer)], tralomethrin and transfluthrin, or DDT or methoxychlor.

(4) Nicotinic acetylcholine receptor (nAChR) competitive modulators, preferably neonicotinoids selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam, or nicotine, or sulfoximines selected from sulfoxaflor, or butenolids selected from flupyradifurone, or mesoionics selected from triflumezopyrim, or pyridylidenes selected from Flupyrimin.

(5) Nicotinic acetylcholine receptor (nAChR) allosteric modulators (site I), preferably spinosyns selected from spinetoram and spinosad.

(6) Glutamate-gated chloride channel (GluCl) allosteric modulators, preferably avermectins/milbemycins selected from abamectin, emamectin benzoate, lepimectin and milbemectin.

(7) Juvenile hormone mimics, preferably juvenile hormone analogues selected from hydroprene, kinoprene and methoprene, or fenoxycarb or pyriproxyfen.

(8) Miscellaneous non-specific (multi-site) inhibitors, preferably alkyl halides selected from methyl bromide and other alkyl halides, or chloropicrine or sulphuryl fluoride or borax or tartar emetic or methyl isocyanate generators selected from diazomet and metam.

(9) Chordotonal organ TRPV channel modulators, preferably pyridine azomethanes selected from pymetrozine and pyrifluquinazon, or pyropenes selected from afidopyropen.

(10) Mite growth inhibitors affecting CHS1 selected from clofentezine, hexythiazox, diflo vidazin and etoxazole.

(11) Microbial disruptors of the insect gut membranes selected from Bacillus thuringiensis subspecies israelensis, Bacillus sphaericus, Bacillus thuringiensis subspecies aizawai, Bacillus thuringiensis subspecies kurstaki, Bacillus thuringiensis subspecies tenebrionis, and B. t. plant proteins selected from Cry 1 Ab, Cry 1 Ac, CrylFa, Cry 1 A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb and Cry34Abl/35Abl.

(12) Inhibitors of mitochondrial ATP synthase, preferably ATP disruptors selected from diafenthiuron, or organotin compounds selected from azocyclotin, cyhexatin and fenbutatin oxide, or propargite or tetradifon.

(13) Uncouplers of oxidative phosphorylation via disruption of the proton gradient selected from chlorfenapyr, DNOC and sulfluramid.

(14) Nicotinic acetylcholine receptor channel blockers selected from bensultap, cartap hydrochloride, thiocylam and thiosultap-sodium.

(15) Inhibitors of chitin biosynthesis affecting CHS1, preferably benzoylureas selected from bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron and triflumuron.

(16) Inhibitors of chitin biosynthesis, type 1 selected from buprofezin. (17) Moulting disruptors (in particular for Diptera, i.e. dipterans) selected from cyromazine.

(18) Ecdysone receptor agonists, preferably diacylhydrazines selected from chromafenozide, halofenozide, methoxyfenozide and tebufenozide.

(19) Octopamine receptor agonists selected from amitraz.

(20) Mitochondrial complex III electron transport inhibitors selected from hydramethylnone, acequinocyl, fluacrypyrim and bifenazate.

(21) Mitochondrial complex I electron transport inhibitors, preferably METI acaricides and insecticides selected from fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad and tolfenpyrad, or rotenone (Derris).

(22) Voltage-dependent sodium channel blockers, preferably oxadiazines selected from indoxacarb, or semicarbazones selected from metaflumizone.

(23) Inhibitors of acetyl CoA carboxylase, preferably tetronic and tetramic acid derivatives selected from spirodiclofen, spiromesifen, spiropidion and spirotetramat.

(24) Mitochondrial complex IV electron transport inhibitors, preferably phosphides selected from aluminium phosphide, calcium phosphide, phosphine and zinc phosphide, or cyanides selected from calcium cyanide, potassium cyanide and sodium cyanide.

(25) Mitochondrial complex II electron transport inhibitors, preferably /?<?m-kctonitrilc derivatives selected from cyenopyrafen and cyflumetofen, or carboxanilides selected from pyflubumide.

(28) Ryanodine receptor modulators, preferably diamides selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, flubendiamide and tetraniliprole.

(29) Chordotonal organ Modulators (with undefined target site) selected from flonicamid.

(30) GABA-gated chlorid channel allosteric modulators, preferably meta-diamides selected from broflanilide, or isoxazoles selected from fluxametamide and isocycloseram.

(31) Baculoviruses, preferably Granuloviruses (GVs) selected from Cydia pomonella GV and Thaumatotibia leucotreta (GV), or Nucleopolyhedro viruses (NPVs) selected from Anticarsia gemmatalis MNPV, Flucypyriprole and Helicoverpa armigera NPV.

(32) Nicotinic acetylcholine receptor allosteric modulators (site II) selected from GS-omega/kappa HXTX-Hvla peptide.

(33) Calcium-activated potassium channel KCa2 modulators, selected from acynonapyr. (34) Mitochondrial complex III electron transfer inhibitors (non-Qo site), selected from flometoquin.

(UN) Compounds of unknown or uncertain Mo A (Target protein responsible for biological activity is unknown, or uncharacterized), selected from azadirachtin, benzoximate, bromopropylate, chinomethionat, dicofol, lime sulfur, mancozeb, pyridalyl, and sulfur.

(UNB) Bacterial agents (non-Bt) of unknown or uncertain Mo A (Target protein responsible for biological activity is unknown or uncharacterized), selected from Burkholderia spp., and Wolbachia pipientis (Zap).

(UNE) Botanical essence including synthetic, extracts and unrefined oils with unknown or uncertain MoA (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Chenopodium ambrosioides near ambrosioides extract and fatty acid monoesters with glycerol or propanediol neem oil.

(UNF) Fungal agents of unknown or uncertain MoA (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Beauveria bassiana strains, Metarhizium anisopliae strain F52, and Paecilomyces fumosoroseus Apopka strain 97.

(UNM) Non-specific mechanical and physical disruptors (Target protein responsible for biological activity is unknown, or uncharacterized), selected from Diatomaceous earth, and mineral oil.

Further active compounds selected from Afoxolaner, Benbenzaramine, Benzpyrimoxan, Chloroprallethrin, Cryolite, Cyclobutrifluram, Cycloxaprid, Cyetpyrafen, Cyhalodiamide, Cyproflanilide (CAS 2375110-88-4), Dicloromezotiaz, Dimpropyridaz, epsilon-Metofluthrin, epsilon-Momfluthrin, Fenmezoditiaz, Fluazaindolizine, Fluchlordiniliprole, Fluensulfone, Flufenerim, Flufenoxystrobin, Flufiprole, Fluhexafon, Fluopyram, Fluralaner, Fufenozide, Flupentiofenox, Flupyroxypyrim, Guadipyr, Heptafluthrin, Imidaclothiz, Indazapyroxamet, Iprodione, kappa-Bifenthrin, kappa-Tefluthrin, Eotilaner, Meperfluthrin, Mivorilaner, Modoflaner, Nicofluprole (CAS 1771741-86-6), Oxazosulfyl, Paichongding, Pyriminostrobin, Sarolaner, Spidoxamat, Spirobudifen, Tetramethylfluthrin, Tetrachlorantraniliprole, Tigolaner, Tiorantraniliprole, Tioxazafen, Thiofluoximate, Trifluenfuronate (CAS 2074661-82-6), Tyclopyrazoflor, lodomethane; furthermore preparations based on Bacillus firmus (1-1582, Votivo), azadirachtin (BioNeem), and Eedprona (Calantha®), and also the following compounds: l-{2-fluoro-4- methyl-5-[(2,2,2-trifhioroethyl)sulphinyl]phenyl}-3-(trifhioromethyl)-lH-l,2,4-triazole-5-amine (known from W02006/043635) (CAS 885026-50-6), 2-chloro-N-[2-{ l-[(2E)-3-(4-chlorophenyl)prop-2-en-l- yl]piperidin-4-yl}-4-(trifluoromethyl)phenyl]isonicotinamide (known from W02006/003494) (CAS 872999-66-1), 3-(4-chloro-2,6-dimethylphenyl)-4-hydroxy-8-methoxy-l,8-diazaspiro[4.5]dec-3-en-2- one (known from WO 2010052161) (CAS 1225292-17-0), 3-(4-chloro-2,6-dimethylphenyl)-8-methoxy- 2-oxo- l,8-diazaspiro[4.5]dec-3-en-4-yl ethyl carbonate (known from EP2647626) (CAS 1440516-42-6), PF1364 (known from JP2010/018586) (CAS 1204776-60-2), (3E)-3-[l-[(6-chloro-3-pyridyl)methyl]-2- pyridylidene]-l,l,l-trifluoro-propan-2-one (known from WO2013/144213) (CAS 1461743-15-6), A-[3- (benzylcarbamoyl)-4-chlorophenyl]-l -methyl-3-(pentafluoroethyl)-4-(trifluoromethyl)-l H-pyrazole-5- carboxamide (known from WO2010/051926) (CAS 1226889-14-0), 5-bromo-4-chloro-A-[4-chloro-2- methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloro-2-pyridyl)pyrazole-3-carboxamide (known from CN103232431) (CAS 1449220-44-3), 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3- isoxazolyl]-2-methyl-A-(cA-l-oxido-3-thietanyl)-benzamide, 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5- (trifluoromethyl)-3-isoxazolyl]-2-methyl-A-(fran5-l-oxido-3-thietanyl)-benzamide and 4-[(5S)-5-(3,5- dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-A-(cA-l-oxido-3-thietanyl) benzamide (known from WO 2013/050317 Al) (CAS 1332628-83-7), A-[3-chloro-l-(3-pyridinyl)-lH- pyrazol-4-yl]-A-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide, (+)-A-[3-chloro-l-(3-pyridinyl)- lH-pyrazol-4-yl]-A-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide and (-)-A-[3-chloro-l-(3- pyridinyl)-lH-pyrazol-4-yl]-A-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide (known from WO 2013/162715 A2, WO 2013/162716 A2, US 2014/0213448 Al) (CAS 1477923-37-7), 5-[[(2E)-3- chloro-2-propen- 1 -yl] amino] - 1 - [2,6-dichloro-4-(trifluoromethyl)phenyl] -4- [(trifluoromethyl)sulfinyl] - lH-pyrazole-3-carbonitrile (known from CN 101337937 A) (CAS 1105672-77-2), 3-bromo-A-[4-chloro- 2-methyl-6-[(methylamino)thioxomethyl]phenyl]-l-(3-chloro-2-pyridinyl)-lH-pyrazole-5-carboxamide, (Liudaibenjiaxuanan, known from CN 103109816 A) (CAS 1232543-85-9); 2V-[4-chloro-2-[[(l,l- dimethylethyl)amino]carbonyl]-6-methylphenyl]-l-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-lH- pyrazole-5-carboxamide (known from WO 2012/034403 Al) (CAS 1268277-22-0), 2V-[2-(5-amino-l, 3,4- thiadiazol-2-yl)-4-chloro-6-methylphenyl] -3-bromo- 1 -(3-chloro-2-pyridinyl)- lH-pyrazole-5- carboxamide (known from WO 2011/085575 Al) (CAS 1233882-22-8), 4-[3-[2,6-dichloro-4-[(3,3- dichloro-2-propen-l-yl)oxy]phenoxy]propoxy]-2-methoxy-6-(trifluoromethyl)-pyrimidine (known from CN 101337940 A) (CAS 1108184-52-6); (2E)- and 2(Z)-2-[2-(4-cyanophenyl)-l-[3-(trifluoromethyl) phenyl] ethylidene] -N- [4-(difluoromethoxy)phenyl] -hydrazinecarboxamide (known from

CN 101715774 A) (CAS 1232543-85-9); 3-(2,2-dichloroethenyl)-2,2-dimethyl-4-(lH-benzimidazol-2- yl)phenyl-cyclopropanecarboxylic acid ester (known from CN 103524422 A) (CAS 1542271-46-4); (4aS) -7 -chloro-2,5 -dihydro-2- [ [(methoxycarbonyl) [4- [(trifluoromethyl)thio] phenyl] amino] carbonyl] - indeno[l,2-e][l,3,4]oxadiazine-4a(3H)-carboxylic acid methyl ester (known from CN 102391261 A) (CAS 1370358-69-2); 6-deoxy-3-(9-ethyl-2,4-di-(9-methyl-, l-[2V-[4-[l-[4-(l,l,2,2,2-pentafluoroethoxy) phenyl]- 1H- 1 ,2,4-triazol-3-yl]phenyl]carbamate] -a-L-mannopyranose (known from

US 2014/0275503 Al) (CAS 1181213-14-8); 8-(2-cyclopropylmethoxy-4-trifluoromethyl-phenoxy)-3- (6-trifluoromethyl-pyridazin-3-yl)-3-aza-bicyclo[3.2.1 ]octane (CAS 1253850-56-4), (8-antz)-8-(2- cyclopropylmethoxy-4-trifluoromethyl-phenoxy)-3-(6-trifluoromethyl-pyridazin-3-yl)-3-aza- bicyclo[3.2.1 ]octane (CAS 933798-27-7), (8-yyn)-8-(2-cyclopropylmethoxy-4-trifluoromethyl-phenoxy) -3-(6-trifluoromethyl-pyridazin-3-yl)-3-aza-bicyclo[3.2.1]octane (known from WO 2007040280 Al, WO 2007040282 Al) (CAS 934001-66-8), N-[4-(aminothioxomethyl)-2-methyl-6-

[(methylamino)carbonyl]phenyl]-3-bromo-l-(3-chloro-2-pyridinyl)-lH-pyrazole-5-carboxamide (known from CN 103265527 A) (CAS 1452877-50-7), 3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-l-methyl- l,8-diazaspiro[4.5]decane-2, 4-dione (known from WO 2014/187846 Al) (CAS 1638765-58-8), 3-(4- chloro-2,6-dimethylphenyl)-8-methoxy-l-methyl-2-oxo-l,8-diazaspiro[4.5]dec-3-en-4-yl-carbonic acid ethyl ester (known from WO 2010/066780 Al, WO 2011151146 Al) (CAS 1229023-00-0), A-[l-(2,6- difluorophenyl)-lH-pyrazol-3-yl]-2-(trifluoromethyl)benzamide (known from WO 2014/053450 Al) (CAS 1594624-87-9), A-[2-(2,6-difluorophenyl)-2H-l,2,3-triazol-4-yl]-2-(trifluoromethyl)benzamide (known from WO 2014/053450 Al) (CAS 1594637-65-6), N-[l-(3,5-difluoro-2-pyridinyl)-lH-pyrazol- 3-yl]-2-(trifluoromethyl)benzamide (known from WO 2014/053450 Al) (CAS 1594626-19-3), N-[3- chloro-l-(3-pyridinyl)-lH-pyrazol-4-yl]-2-(methylsulfonyl)-propanamide (known from WO 2019/236274 Al) (CAS 2396747-83-2), N-[2-bromo-4-[l,2,2,2-tetrafluoro-l-(trifluoromethyl)ethyl]-6- (trifhroromethyl)phenyl]-2-fluoro-3-[(4-fluorobenzoyl)amino]-benzamide (known from WO 2019059412 Al) (CAS 1207977-87-4), 2-(5-cyclopropyl-3-ethylsulfonyl-2-pyridyl)-5-(trifluoromethylsulfinyl)-l,3- benzoxazole (known from WO 2017146226 Al) (CAS 2128706-04-5), 6-(5-cyclopropyl-3-ethylsulfonyl- 2-pyridyl)-2,2-difluoro-7-methyl-[l,3]dioxolo[4,5-f]benzimidazole (known from WO 2020013147 Al) (CAS 2408220-91-5), l-[6-(2,2-difluoro-7-methyl-[l,3]dioxolo[4,5-f]benzimidazole-6-yl)-5- ethylsulfonyl-3-pyridyl]cyclopropanecarbonitrile (known from WO 2020013147 Al) (CAS 2408220-94- 8), 2-(3-ethylsulfonyl-2-pyridyl)-5-(2,2,3,3,3-pentafluoropropoxy)pyrazine (known from WO 2017065228 Al) (CAS 2095470-94-1).

The active compound combinations can preferably be used as pesticides. They are active against normally sensitive and resistant species and against all or some stages of development. The abovementioned pests include: pests from the phylum of the Arthropoda, in particular from the class of the Arachnida, for example Acarus spp., for example Acarus siro, Aceria kuko, Aceria sheldoni, Aculops spp., Aculus spp., for example Aculus fockeui, Aculus schlechtendali, Amblyomma spp., Amphitetranychus viennensis, Argas spp., Boophilus spp., Brevipalpus spp., for example Brevipalpus phoenicis, Bryobia graminum, Bryobia praetiosa, Centruroides spp., Chorioptes spp., Dermanyssus gallinae, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermacentor spp., Eotetranychus spp., for example Eotetranychus hicoriae, Epitrimerus pyri, Eutetranychus spp., for example Eutetranychus banksi, Eriophyes spp., for example Eriophyes pyri, Glycyphagus domesticus, Halotydeus destructor, Hemitarsonemus spp., for example Hemitarsonemus latus (=Polyphagotarsonemus latus), Hyalomma spp., Ixodes spp., Latrodectus spp., Loxosceles spp., Neutrombicula autumnalis, Nuphersa spp., Oligonychus spp., for example Oligonychus coffeae, Oligonychus coniferarum, Oligonychus ilicis, Oligonychus indicus, Oligonychus mangiferus, Oligonychus pratensis, Oligonychus punicae, Oligonychus yothersi, Ornithodorus spp., Ornithonyssus spp., Panonychus spp., for example Panonychus citri (=Metatetranychus citri), Panonychus ulmi (=Metatetranychus ulmi), Phyllocoptruta oleivora, Platytetranychus multidigituli, Polyphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Scorpio maurus, Steneotarsonemus spp., Steneotarsonemus spinki, Tarsonemus spp., for example Tarsonemus confusus, Tarsonemus pallidus, Tetranychus spp., for example Tetranychus canadensis, Tetranychus cinnabarinus, Tetranychus turkestani, Tetranychus urticae, Trombicula alfreddugesi, Vaejovis spp., Vasates lycopersici; from the class of the Chilopoda, for example Geophilus spp., Scutigera spp.; from the order or the class of the Collembola, for example Onychiurus armatus; Sminthurus viridis; from the class of the Diplopoda, for example Blaniulus guttulatus; from the class of the Insecta, for example from the order of the Blattodea, for example Blatta orientalis, Blattella asahinai, Blattella germanica, Leucophaea maderae, Loboptera decipiens, Neostylopyga rhombifolia, Panchlora spp., Parcoblatta spp., Periplaneta spp., for example Periplaneta americana, Periplaneta australasiae, Pycnoscelus surinamensis, Supella longipalpa; from the order of the Coleoptera, for example Acalymma vittatum, Acanthoscelides obtectus, Adoretus spp., Aethina tumida, Agelastica alni, Agrilus spp., for example Agrilus planipennis, Agrilus coxalis, Agrilus bilineatus, Agrilus anxius, Agriotes spp., for example Agriotes linneatus, Agriotes mancus, Agriotes obscurus, Alphitobius diaperinus, Amphimallon solstitialis, Anobium punctatum, Anomala dubia, Anoplophora spp., for example Anoplophora glabripennis, Anthonomus spp., for example Anthonomus grandis, Anthrenus spp., Apion spp., Apogonia spp., Athous haemorrhoidales, Atomaria spp., for example Atomaria linearis, Attagenus spp., Baris caerulescens, Bruchidius obtectus, Bruchus spp., for example Bruchus pisorum, Bruchus rufimanus, Cassida spp., Cerotoma trifurcata, Ceutorrhynchus spp., for example Ceutorrhynchus assimilis, Ceutorrhynchus quadridens, Ceutorrhynchus rapae, Chaetocnema spp., for example Chaetocnema confinis, Chaetocnema denticulata, Chaetocnema ectypa, Cleonus mendicus, Conoderus spp., Cosmopolites spp., for example Cosmopolites sordidus, Costelytra zealandica, Ctenicera spp., Curculio spp., for example Curculio caryae, Curculio caryatrypes,Curculio obtusus, Curculio sayi, Cryptolestes ferrugineus, Cryptolestes pusillus, Cryptorhynchus lapathi, Cryptorhynchus mangiferae, Cylindrocopturus spp., Cylindrocopturus adspersus, Cylindrocopturus furnissi, Dendroctonus spp., for example Dendroctonus ponderosae, Dermestes spp., Diabrotica spp., for example Diabrotica balteata, Diabrotica barberi, Diabrotica undecimpunctata howardi, Diabrotica undecimpunctata undecimpunctata, Diabrotica virgifera virgifera, Diabrotica virgifera zeae, Dichocrocis spp., Dicladispa armigera, Diloboderus spp., Epicaerus spp., Epilachna spp., for example Epilachna borealis, Epilachna varivestis, Epitrix spp., for example Epitrix cucumeris, Epitrix fuscula, Epitrix hirtipennis, Epitrix subcrinita, Epitrix tuberis, Faustinus spp., Gibbium psylloides, Gnathocerus cornutus, Hellula undalis, Heteronychus arator, Heteronyx spp., Hoplia argentea, Hylamorpha elegans, Hylotrupes bajulus, Hypera postica, Hypomeces squamosus, Hypothenemus spp., for example Hypothenemus hampei, Hypothenemus obscurus, Hypothenemus pubescens, Lachnosterna consanguinea, Lasioderma serricorne, Latheticus oryzae, Lathridius spp., Lerna spp., Leptinotarsa decemlineata, Leucoptera spp., for example Leucoptera coffeella, Limonius ectypus, Lissorhoptrus oryzophilus, Listronotus (= Hyperodes) spp., Lixus spp., Luperodes spp., Luperomorpha xanthodera, Lyctus spp., Megacyllene spp., for example Megacyllene robiniae, Megascelis spp., Melanotus spp., for example Melanotus longulus oregonensis, Meligethes aeneus, Melolontha spp., for example Melolontha melolontha, Migdolus spp., Monochamus spp., Naupactus xanthographus, Necrobia spp., Neogalerucella spp., Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Oryzaphagus oryzae, Otiorhynchus spp., for example Otiorhynchus cribricollis, Otiorhynchus ligustici, Otiorhynchus ovatus, Otiorhynchus rugosostriarus, Otiorhynchus sulcatus, Oulema spp., for example Oulema melanopus, Oulema oryzae, Oxycetonia jucunda, Phaedon cochleariae, Phyllophaga spp., Phyllophaga helleri, Phyllotreta spp., for example Phyllotreta armoraciae, Phyllotreta pusilia, Phyllotreta ramosa, Phyllotreta striolata, Popillia japonica, Premnotrypes spp., Prostephanus truncatus, Psylliodes spp., for example Psylliodes affinis, Psylliodes chrysocephala, Psylliodes punctulata, Ptinus spp., Rhizobius ventralis, Rhizopertha dominica, Rhynchophorus spp., Rhynchophorus ferrugineus, Rhynchophorus palmarum, Scolytus spp., for example Scolytus multistriatus, Sinoxylon perforans, Sitophilus spp., for example Sitophilus granarius, Sitophilus linearis, Sitophilus oryzae, Sitophilus zeamais, Sphenophorus spp., Stegobium paniceum, Sternechus spp., for example Sternechus paludatus, Symphyletes spp., Tanymecus spp., for example Tanymecus dilaticollis, Tanymecus indicus, Tanymecus palliatus, Tenebrio molitor, Tenebrioides mauretanicus, Tribolium spp., for example Tribolium audax, Tribolium castaneum, Tribolium confusum, Trogoderma spp., Tychius spp., Xylotrechus spp., Zabrus spp., for example Zabrus tenebrioides; from the order of the Dermaptera, for example Anisolabis maritime, Forficula auricularia, Labidura riparia; from the order of the Diptera, for example Aedes spp., for example Aedes aegypti, Aedes albopictus, Aedes sticticus, Aedes vexans, Agromyza spp., for example Agromyza frontella, Agromyza parvicornis, Anastrepha spp., Anopheles spp., for example Anopheles quadrimaculatus, Anopheles gambiae, Asphondylia spp., Bactrocera spp., for example Bactrocera cucurbitae, Bactrocera dorsalis, Bactrocera oleae, Bibio hortulanus, Calliphora erythrocephala, Calliphora vicina, Ceratitis capitata, Chironomus spp., Chrysomya spp., Chrysops spp., Chrysozona pluvialis, Cochliomya spp., Contarinia spp., for example Contarinia johnsoni, Contarinia nasturtii, Contarinia pyrivora, Contarinia schulzi, Contarinia sorghicola, Contarinia tritici,Cordylobia anthropophaga, Cricotopus sylvestris, Culex spp., for example Culex pipiens, Culex quinquefasciatus, Culicoides spp., Culiseta spp., Cuterebra spp., Dacus oleae, Dasineura spp., for example Dasineura brassicae, Delia spp., for example Delia antiqua, Delia coarctata, Delia florilega, Delia platura, Delia radicum, Dermatobia hominis, Drosophila spp., for example Drosphila melanogaster, Drosophila suzukii, Echinocnemus spp., Euleia heraclei, Fannia spp., Gasterophilus spp., Glossina spp., Haematopota spp., Hydrellia spp., Hydrellia griseola, Hylemya spp., Hippobosca spp., Hypoderma spp., Liriomyza spp., for example Liriomyza brassicae, Liriomyza huidobrensis, Liriomyza sativae, Lucilia spp., for example Lucilia cuprina, Lutzomyia spp., Mansonia spp., Musca spp., for example Musca domestica, Musca domestica vicina, Oestrus spp., Oscinella frit, Paratanytarsus spp., Paralauterborniella subcincta, Pegomya or Pegomyia spp., for example Pegomya betae, Pegomya hyoscyami, Pegomya rubivora, Phlebotomus spp., Phorbia spp., Phormia spp., Piophila casei, Platyparea poeciloptera, Prodiplosis spp., Psila rosae, Rhagoletis spp., for example Rhagoletis cingulata, Rhagoletis completa, Rhagoletis fausta, Rhagoletis indifferens, Rhagoletis mendax, Rhagoletis pomonella, Sarcophaga spp., Simulium spp., for example Simulium meridionale, Stomoxys spp., Tabanus spp., Tetanops spp., Tipula spp., for example Tipula paludosa, Tipula simplex, Toxotrypana curvicauda; from the order of the Hemiptera, for example Acizzia acaciaebaileyanae, Acizzia dodonaeae, Acizzia uncatoides, Acrida turrita, Acyrthosipon spp., for example Acyrthosiphon pisum, Acrogonia spp., Aeneolamia spp., Agonoscena spp., Aleurocanthus spp., Aleyrodes proletella, Aleurolobus barodensis, Aleurothrixus floccosus, Allocaridara malayensis, Amrasca spp., for example Amrasca bigutulla, Amrasca devastans, Anuraphis cardui, Aonidiella spp., for example Aonidiella aurantii, Aonidiella citrina, Aonidiella inornata, Aphanostigma piri, Aphis spp., for example Aphis citricola, Aphis craccivora, Aphis fabae, Aphis forbesi, Aphis glycines, Aphis gossypii, Aphis hederae, Aphis illinoisensis, Aphis middletoni, Aphis nasturtii, Aphis nerii, Aphis pomi, Aphis spiraecola, Aphis viburniphila, Arboridia apicalis, Arytainilla spp., Aspidiella spp., Aspidiotus spp., for example Aspidiotus nerii, Atanus spp., Aulacorthum solani, Bemisia tabaci, Blastopsylla occidentalis, Boreioglycaspis melaleucae, Brachycaudus helichrysi, Brachycolus spp., Brevicoryne brassicae, Cacopsylla spp., for example Cacopsylla pyricola, Calligypona marginata, Capulinia spp., Carneocephala fulgida, Ceratovacuna lanigera, Cercopidae, Ceroplastes spp., Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chondracris rosea, Chromaphis juglandicola, Chrysomphalus aonidum, Chrysomphalus ficus, Cicadulina mbila, Coccomytilus halli, Coccus spp., for example Coccus hesperidum, Coccus longulus, Coccus pseudomagnoliarum, Coccus viridis, Cryptomyzus ribis, Cryptoneossa spp., Ctenarytaina spp., Dalbulus spp., Dialeurodes chittendeni, Dialeurodes citri, Diaphorina citri, Diaspis spp., Diuraphis spp., Doralis spp., Drosicha spp., Dysaphis spp., for example Dysaphis apiifolia, Dysaphis plantaginea, Dysaphis tulipae, Dysmicoccus spp., Empoasca spp., for example Empoasca abrupta, Empoasca fabae, Empoasca maligna, Empoasca solana, Empoasca stevensi, Eriosoma spp., for example Eriosoma americanum, Eriosoma lanigerum, Eriosoma pyricola, Erythroneura spp., Eucalyptolyma spp., Euphyllura spp., Euscelis bilobatus, Ferrisia spp., Fiorinia spp., Furcaspis oceanica, Geococcus coffeae, Glycaspis spp., Heteropsylla cubana, Heteropsylla spinulosa, Homalodisca coagulata, Hyalopterus arundinis, Hyalopterus pruni, Icerya spp., for example Icerya purchasi, Idiocerus spp., Idioscopus spp., Laodelphax striatellus, Lecanium spp., for example Lecanium corni (=Parthenolecanium corni), Lepidosaphes spp., for example Lepidosaphes ulmi, Lipaphis erysimi, Lopholeucaspis japonica, Lycorma delicatula, Macrosiphum spp., for example Macrosiphum euphorbiae, Macrosiphum lilii, Macrosiphum rosae, Macrosteles facifrons, Mahanarva spp., Melanaphis sacchari, Metcalfiella spp., Metcalfa pruinosa, Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzus spp., for example Myzus ascalonicus, Myzus cerasi, Myzus ligustri, Myzus ornatus, Myzus persicae,. Myzus nicotianae, Nasonovia ribisnigri, Neomaskellia spp., Nephotettix spp., for example Nephotettix cincticeps,, Nephotettix nigropictus, Nettigoniclla spectra, Nilaparvata lugens, Oncometopia spp., Orthezia praelonga, Oxya chinensis, Pachypsylla spp., Parabemisia myricae, Paratrioza spp., for example Paratrioza cockerelli, Parlatoria spp., Pemphigus spp., for example Pemphigus bursarius, Pemphigus populivenae, Peregrinus maidis, Perkinsiella spp., Phenacoccus spp., for example Phenacoccus madeirensis, Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp., for example Phylloxera devastatrix, Phylloxera notabilis, Pinnaspis aspidistrae, Pianococcus spp., for example Pianococcus citri, Prosopidopsylla flava, Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcus spp., for example Pseudococcus calceolariae, Pseudococcus comstocki, Pseudococcus longispinus, Pseudococcus maritimus, Pseudococcus viburni, Psyllopsis spp., Psylla spp., for example Psylla buxi, Psylla mali, Psylla pyri, Pteromalus spp., Pulvinaria spp., Pyrilla spp., Quadraspidiotus spp., for example Quadraspidiotus juglansregiae, Quadraspidiotus ostreaeformis, Quadraspidiotus perniciosus, Quesada gigas, Rastrococcus spp., Rhopalosiphum spp., for example Rhopalosiphum maidis, Rhopalosiphum oxyacanthae, Rhopalosiphum padi, Rhopalosiphum rufiabdominale, Saissetia spp., for example Saissetia coffeae, Saissetia miranda, Saissetia neglecta, Saissetia oleae, Scaphoideus titanus, Schizaphis graminum, Selenaspidus articulatus, Sipha flava, Sitobion avenae, Sogata spp., Sogatella furcifera, Sogatodes spp., Stictocephala festina, Siphoninus phillyreae, Tenalaphara malayensis,Tetragonocephela spp., Tinocallis caryaefoliae, Tomaspis spp., Toxoptera spp., for example Toxoptera aurantii, Toxoptera citricidus, Trialeurodes vaporariorum, Trioza spp., for example Trioza diospyri, Typhlocyba spp., Unaspis spp., Viteus vitifolii, Zygina spp.; from the suborder of the Heteroptera, for example Aelia spp., Anasa tristis, Antestiopsis spp., Boisea spp., Blissus spp., Calocoris spp., Campy lomma livida, Cavelerius spp., Cimex spp., for example Cimex adjunctus, Cimex hemipterus, Cimex lectularius, Cimex pilosellus, Collaria spp., Creontiades dilutus, Dasynus piperis, Dichelops furcatus, Diconocoris hewetti, Dysdercus spp., Euschistus spp., for example Euschistus heros, Euschistus servus, Euschistus tristigmus, Euschistus variolarius, Eurydema spp., Eurygaster spp., Halyomorpha halys, Heliopeltis spp., Horcias nobilellus, Leptocorisa spp., Leptocorisa varicornis, Leptoglossus occidentalis, Leptoglossus phyllopus, Lygocoris spp., for example Lygocoris pabulinus, Lygus spp., for example Lygus elisus, Lygus hesperus, Lygus lineolaris, Macropes excavatus, Megacopta cribraria, Miridae, Monalonion atratum, Nezara spp., for example Nezara viridula, Nysius spp., Oebalus spp., Pentomidae, Piesma quadrata, Piezodorus spp., for example Piezodorus guildinii, Psallus spp., Pseudacysta persea, Rhodnius spp., Sahlbergella singularis, Scaptocoris castanea, Scotinophora spp., Stephanitis nashi, Tibraca spp., Triatoma spp.; from the order of the Hymenoptera, for example Acromyrmex spp., Athalia spp., for example Athalia rosae, Atta spp., Camponotus spp., Dolichovespula spp., Diprion spp., for example Diprion similis, Hoplocampa spp., for example Hoplocampa cookei, Hoplocampa testudinea, Lasius spp., Linepithema (Iridiomyrmex) humile, Monomorium pharaonis, Paratrechina spp., Paravespula spp., Plagiolepis spp., Sirex spp., for example Sirex noctilio, Solenopsis invicta, Tapinoma spp., Technomyrmex albipes, Urocerus spp., Vespa spp., for example Vespa crabro, Wasmannia auropunctata, Xeris spp.; from the order of the Isopoda, for example Armadillidium vulgare, Oniscus asellus, Porcellio scaber; from the order of the Isoptera, for example Coptotermes spp., for example Coptotermes formosanus, Cornitermes cumulans, Cryptotermes spp., Incisitermes spp., Kalotermes spp., Microtermes obesi, Nasutitermes spp., Odontotermes spp., Porotermes spp., Reticulitermes spp., for example Reticulitermes flavipes, Reticulitermes hesperus; from the order of the Lepidoptera, for example Achroia grisella, Acronicta major, Adoxophyes spp., for example Adoxophyes orana, Aedia leucomelas, Agrotis spp., for example Agrotis segetum, Agrotis ipsilon, Alabama spp., for example Alabama argillacea, Amyelois transitella, Anarsia spp., Anticarsia spp., for example Anticarsia gemmatalis, Argyroploce spp., Autographa spp., Barathra brassicae, Blastodacna atra, Borbo cinnara, Bucculatrix thurberiella, Bupalus piniarius, Busseola spp., Cacoecia spp., Caloptilia theivora, Capua reticulana, Carpocapsa pomonella, Carposina niponensis, Cheimatobia brumata, Chilo spp., for example Chilo plejadellus, Chilo suppressalis, Choreutis pariana, Choristoneura spp., Chrysodeixis chalcites, Clysia ambiguella, Cnaphalocerus spp., Cnaphalocrocis medinalis, Cnephasia spp., Conopomorpha spp., Conotrachelus spp., Copitarsia spp., Cydia spp., for example Cydia nigricana, Cydia pomonella, Dalaca noctuides, Diaphania spp., Diparopsis spp., Diatraea saccharalis, Dioryctria spp., for example Dioryctria zimmermani, Earias spp., Ecdytolopha aurantium, Elasmopalpus lignosellus, Eldana saccharina, Ephestia spp., for example Ephestia elutella, Ephestia kuehniella, Epinotia spp., Epiphyas postvittana, Erannis spp., Erschoviella musculana, Etiella spp., Eudocima spp., Eulia spp., Eupoecilia ambiguella, Euproctis spp., for example Euproctis chrysorrhoea, Euxoa spp., Feltia spp., Galleria mellonella, Gracillaria spp., Grapholitha spp., for example Grapholita molesta, Grapholita prunivora, Hedy lepta spp., Helicoverpa spp., for example Helicoverpa armigera, Helicoverpa zea, Heliothis spp., for example Heliothis virescens, Hepialus spp., for example Hepialus humuli, Hofmannophila pseudospretella, Homoeosoma spp., Homona spp., Hyponomeuta padella, Kakivoria flavofasciata, Lampides spp., Laphygma spp., Laspeyresia molesta, Leucinodes orbonalis, Leucoptera spp., for example Leucoptera coffeella, Lithocolletis spp., for example Lithocolletis blancardella, Lithophane antennata, Lobesia spp., for example Lobesia botrana, Loxagrotis albicosta, Lymantria spp., for example Lymantria dispar, Lyonetia spp., for example Lyonetia clerkella, Malacosoma neustria, Maruca testulalis, Mamestra brassicae, Melanitis leda, Mocis spp., Monopis obviella, Mythimna separata, Nemapogon cloacellus, Nymphula spp., Oiketicus spp., Omphisa spp., Operophtera spp., Oria spp., Orthaga spp., Ostrinia spp., for example Ostrinia nubilalis, Panolis flammea, Parnara spp., Pectinophora spp., for example Pectinophora gossypiella, Perileucoptera spp., Phthorimaea spp., for example Phthorimaea operculella, Phyllocnistis citrella, Phyllonorycter spp., for example Phyllonorycter blancardella, Phyllonorycter crataegella, Pieris spp., for example Pieris rapae, Platynota stultana, Plodia interpunctella, Plusia spp., Plutella xylostella (=Plutella maculipennis), Podesia spp., for example Podesia syringae, Prays spp., Prodenia spp., Protoparce spp., Pseudaletia spp., for example Pseudaletia unipuncta, Pseudoplusia includens, Pyrausta nubilalis, Rachiplusia nu, Schoenobius spp., for example Schoenobius bipunctifer, Scirpophaga spp., for example Scirpophaga innotata, Scotia segetum, Sesamia spp., for example Sesamia inferens, Sparganothis spp., Spodoptera spp., for example Spodoptera eradiana, Spodoptera exigua, Spodoptera frugiperda, Spodoptera praefica, Stathmopoda spp., Stenoma spp., Stomopteryx subsecivella, Synanthedon spp., Tecia solanivora, Thaumetopoea spp., Thermesia gemmatalis, Tinea cloacella, Tinea pellionella, Tineola bisselliella, Tortrix spp., Trichophaga tapetzella, Trichoplusia spp., for example Trichoplusia ni, Tryporyza incertulas, Tuta absoluta, Virachola spp.; from the order of the Orthoptera or Saltatoria, for example Acheta domesticus, Dichroplus spp., Gryllotalpa spp., for example Gryllotalpa gryllotalpa, Hieroglyphus spp., Locusta spp., for example Locusta migratoria, Melanoplus spp., for example Melanoplus devastator, Paratlanticus ussuriensis, Schistocerca gregaria; from the order of the Phthiraptera, for example Damalinia spp., Haematopinus spp., Linognathus spp., Pediculus spp., Phylloxera vastatrix, Phthirus pubis, Trichodectes spp.; from the order of the Psocoptera, for example Lepinotus spp., Liposcelis spp.; from the order of the Siphonaptera, for example, Ceratophyllus spp., Ctenocephalides spp., for example Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, Tunga penetrans, Xenopsylla cheopis; from the order of the Thysanoptera, for example Anaphothrips obscuras, Baliothrips biformis, Chaetanaphothrips leeuweni, Drepanothrips reuteri, Enneothrips flavens, Frankliniella spp., for example Frankliniella fusca, Frankliniella occidentalis, Frankliniella schultzei, Frankliniella tritici, Frankliniella vaccinii, Frankliniella williamsi, Haplothrips spp., Heliothrips spp., Hercinothrips femoralis, Kakothrips spp., Rhipiphorothrips cruentatus, Scirtothrips spp., Taeniothrips cardamomi, Thrips spp., for example Thrips palmi, Thrips tabaci; from the order of the Zygentoma (= Thysanura), for example Ctenolepisma spp., Eepisma saccharina, Eepismodes inquilinus, Thermobia domestica; from the class of the Symphyla, for example Scutigerella spp., for example Scutigerella immaculata; pests from the phylum of the Mollusca, for example from the class of the Bivalvia, for example Dreissena spp., and also from the class of the Gastropoda, for example Arion spp., for example Arion ater rufus, Biomphalaria spp., Bulinus spp., Deroceras spp., for example Deroceras laeve, Galba spp., Eymnaea spp., Oncomelania spp., Pomacea spp., Succinea spp.; plant pests from the phylum of the Nematoda, i.e. phytoparasitic nematodes, in particular Aglenchus spp., for example Aglenchus agricola, Anguina spp., for example Anguina tritici, Aphelenchoides spp., for example Aphelenchoides arachidis, Aphelenchoides fragariae, Belonolaimus spp., for example Belonolaimus gracilis, Belonolaimus longicaudatus, Belonolaimus nortoni, Bursaphelenchus spp., for example Bursaphelenchus cocophilus, Bursaphelenchus eremus, Bursaphelenchus xylophilus, Cacopaurus spp., for example Cacopaurus pestis, Criconemella spp., for example Criconemella curvata, Criconemella onoensis, Criconemella ornata, Criconemella rusium, Criconemella xenoplax (= Mesocriconema xenoplax), Criconemoides spp., for example Criconemoides ferniae, Criconemoides onoense, Criconemoides ornatum, Ditylenchus spp., for example Ditylenchus dipsaci, Dolichodorus spp., Globodera spp., for example Globodera pallida, Globodera rostochiensis, Helicotylenchus spp., for example Helicotylenchus dihystera, Hemicriconemoides spp., Hemicycliophora spp., Heterodera spp., for example Heterodera avenae, Heterodera glycines, Heterodera schachtii, Hirschmaniella spp., Hoplolaimus spp., Longidorus spp., for example Longidorus africanus, Meloidogyne spp., for example Meloidogyne chitwoodi, Meloidogyne fallax, Meloidogyne hapla, Meloidogyne incognita, Meloinema spp., Nacobbus spp., Neotylenchus spp., Paralongidorus spp., Paraphelenchus spp., Paratrichodorus spp., for example Paratrichodorus minor, Paratylenchus spp., Pratylenchus spp., for example Pratylenchus penetrans, Pseudohalenchus spp., Psilenchus spp., Punctodera spp., Quinisulcius spp., Radopholus spp., for example Radopholus citrophilus, Radopholus similis, Rotylenchulus spp., Rotylenchus spp., Scutellonema spp., Subanguina spp., Trichodorus spp., for example Trichodorus obtusus, Trichodorus primitivus, Tylenchorhynchus spp., for example Tylenchorhynchus annulatus, Tylenchulus spp., for example Tylenchulus semipenetrans, Xiphinema spp., for example Xiphinema index.

Pathogens

Non-limiting examples of pathogens of fungal diseases which may be treated in accordance with the invention include: diseases caused by powdery mildew pathogens, for example Blumeria species, for example Blumeria graminis', Podosphaera species, for example Podosphaera leucotricha', Sphaerotheca species, for example Sphaero theca fuliginea', Uncinula species, for example Erysiphe necator, diseases caused by rust disease pathogens, for example Gymnosporangium species, for example Gymnosporangium sabinae', Hemileia species, for example Hemileia vastatrix', Phakopsora species, for example Phakopsora pachyrhizi, Phakopsora meibomiae or Phakopsora euvitis', Puccinia species, for example Puccinia recondita, Puccinia graminis oder Puccinia striiformis', Uromyces species, for example Uromyces appendiculatus', diseases caused by pathogens from the group of the Oomycetes, for example Albugo species, for example Albugo Candida', Bremia species, for example Bremia lactucac, Peronospora species, for example Peronospora pisi or P. brassicae', Phytophthora species, for example Phytophthora infestans', Plasmopara species, for example Plasmopara viticola', Pseudoperonospora species, for example Pseudoperonospora humuli or Pseudoperonospora cubensis', Pythium species, for example Pythium ultimunr, leaf blotch diseases and leaf wilt diseases caused, for example, by Altemaria species, for example Altemaria solani', Cercospora species, for example Cercospora beticola', Cladiosporium species, for example Cladiosporium cucumerinunr, Cochliobolus species, for example Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium) or Cochliobolus miyabeanus', Colletotrichum species, for example Colletotrichum lindemuthanium', Corynespora species, for example Corynespora cassiicokr, Cycloconium species, for example Cycloconium oleaginunr, Diaporthe species, for example Diaporthe citri', Elsinoe species, for example Elsinoe fawcettii', Gloeosporium species, for example Gloeosporium laeticolor, Glomerella species, for example Glomerella cingulata', Guignardia species, for example Guignardia bidwelli', Leptosphaeria species, for example Leptosphaeria maculans', Magnaporthe species, for example Magnaporthe grisecr, Microdochium species, for example Microdochium nivalc, Mycosphaerella species, for example Zymoseptoria tritici (syn: Mycosphaerella graminicold), Mycosphaerella arachidicola or Mycosphaerella fijiensis', Phaeosphaeria species, for example Phaeosphaeria nodorunr, Phyllachora species, for example Phyllachora maydis, Pyrenophora species, for example Pyrenophora teres or Pyrenophora tritici repends', Ramularia species, for example Ramularia collo-cygni or Ramularia areola', Rhynchosporium species, for example Rhynchosporium secalis,' Septoria species, for example Septoria apii or Septoria lycopersici', Stagonospora species, for example Stagonospora nodorunr, Typhula species, for example Typhula incarnata', Venturia species, for example Venturia inaequalis', root and stem diseases caused, for example, by Corticium species, for example Corticium graminearunr, Fusarium species, for example Fusarium oxysporunr, Gaeumannomyces species, for example Gaeumannomyces graminis', Plasmodiophora species, for example Plasmodiophora brassicac, Rhizoctonia species, for example Rhizoctonia solani', Sarocladium species, for example Sarocladium oryzac, Sclerotium species, for example Sclerotium oryz.ae Tapesia species, for example Tapesia acuformis', Thielaviopsis species, for example Thielaviopsis basicokr, ear and panicle diseases (including corn cobs) caused, for example, by Altemaria species, for example Alternaria spp.', Aspergillus species, for example Aspergillus flavus', Cladosporium species, for example Cladosporium cladosporioides', Claviceps species, for example Claviceps purpurea', Fusarium species, for example Fusarium culmorunr, Gibberella species, for example Gibberella zeac, Monographella species, for example Monographella nivalis', Stagnospora species, for example Stagnospora nodorunr, diseases caused by smut fungi, for example Sphacelotheca species, for example Sphacelotheca reiliana', Tilleda species, for example Tilleda caries or Tilleda controversy, Urocysds species, for example Urocystis occulta', Usdlago species, for example Usdlago nuda', fruit rot caused, for example, by Aspergillus species, for example Aspergillus flavus', Botrytis species, for example Botrytis cinerea', Monilinia species, for example Monilinia Icmr, Penicillium species, for example Penicillium expansum or Penicillium purpurogenunr, Rhizopus species, for example Rhizopus stolonifer, Sclerotinia species, for example Sclerotinia sclerotiorunr, Verdcilium species, for example Verdcilium alboatrunr, seed- and soil-borne rot and wilt diseases, and also diseases of seedlings, caused, for example, by Altemaria species, for example Altemaria brassicicokr, Aphanomyces species, for example Aphanomyces euteiches', Ascochyta species, for example Ascochyta lends', Aspergillus species, for example Aspergillus flavus', Cladosporium species, for example Cladosporium herbarum', Cochliobolus species, for example Cochliobolus sativus (conidial form: Drechslera, Bipolaris Syn: Helminthosporium)' Colletotrichum species, for example Colletotrichum coccodes', Fusarium species, for example Fusarium culmorunr, Gibberella species, for example Gibberella zeac, Macrophomina species, for example Macrophomina phaseolina', Microdochium species, for example Microdochium nivale: Monographella species, for example Monographella nivalis', Penicillium species, for example Penicillium expansum', Phoma species, for example Phoma lingam', Phomopsis species, for example Phomopsis sojac, Phytophthora species, for example Phytophthora cactorunr, Pyrenophora species, for example Pyrenophora graminea', Pyricularia species, for example Pyricularia oryzac, Pythium species, for example Pythium ultimunr, Rhizoctonia species, for example Rhizoctonia solani', Rhizopus species, for example Rhizopus oryzac, Sclerotium species, for example Sclerotium rolfsii', Septoria species, for example Septoria nodorum', Typhula species, for example Typhula incarnata', Verticillium species, for example Verticillium dahliac, cancers, galls and witches’ broom caused, for example, by Nectria species, for example Nectria galligena', wilt diseases caused, for example, by Verticillium species, for example Verticillium longisporunr, Fusarium species, for example Fusarium oxysporunr, deformations of leaves, flowers and fruits caused, for example, by Exobasidium species, for example Exobasidium vexans', Taphrina species, for example Taphrina deformans', degenerative diseases in woody plants, caused, for example, by Esca species, for example Phaeomoniella chlamydospora, Phaeoacremonium aleophilum or Fomitiporia mediterranea', Ganoderma species, for example Ganoderma boninensc, diseases of plant tubers caused, for example, by Rhizoctonia species, for example Rhizoctonia solani', Helminthosporium species, for example Helminthosporium solani', diseases caused by bacterial pathogens, for example Xanthomonas species, for example Xanthomonas campestris pv. oryzac, Pseudomonas species, for example Pseudomonas syringae pv. lachrymans', Erwinia species, for example Erwinia amylovora', Liberibacter species, for example Liberibacter asiaticus', Xyella species, for example Xylella fastidiosa', Ralstonia species, for example Ralstonia solanacearum', Dickeya species, for example Dickeya solani', Clavibacter species, for example Clavibacter michiganensis', Streptomyces species, for example Streptomyces scabies. diseases of soya beans:

Fungal diseases on leaves, stems, pods and seeds caused, for example, by Altemaria leaf spot (Altemaria spec, atrans tenuissima), Anthracnose (Colletotrichum gloeosporoides dematium var. truncatum), brown spot (Septoria glycines), cercospora leaf spot and blight (Cercospora kikuchii), choanephora leaf blight (Choanephora infundibulifera trispora (Syn.)), dactuliophora leaf spot (Dactuliophora glycines), downy mildew (Peronospora manshurica), drechslera blight (Drechslera glycini), frogeye leaf spot (Cercospora sojina), leptosphaerulina leaf spot (Leptosphaerulina trifolii), phyllostica leaf spot (Phyllosticta sojaecola), pod and stem blight (Phomopsis sojae), powdery mildew (Microsphaera diffusa), pyrenochaeta leaf spot (Pyrenochaeta glycines), rhizoctonia aerial, foliage, and web blight (Rhizoctonia solani), rust (Phakopsora pachyrhizi, Phakopsora meibomiae, Phakopsora euvitis), scab (Sphaceloma glycines), stemphylium leaf blight (Stemphylium botryosum), sudden death syndrome (Fusarium virguliforme), target spot (Corynespora cassiicola).

Fungal diseases on roots and the stem base caused, for example, by black root rot (Calonectria crotalariae), charcoal rot (Macrophomina phaseolina), fusarium blight or wilt, root rot, and pod and collar rot (Fusarium oxysporum, Fusarium orthoceras, Fusarium semitectum, Fusarium equiseti), mycoleptodiscus root rot (Mycoleptodiscus terrestris), neocosmospora (Neocosmospora vasinfecta), pod and stem blight (Diaporthe phaseolorum), stem canker (Diaporthe phaseolorum var. caulivora), phytophthora rot (Phytophthora megasperma), brown stem rot (Phialophora gregata), pythium rot (Pythium aphanidermatum, Pythium irregulare, Pythium debaryanum, Pythium myriotylum, Pythium ultimum), rhizoctonia root rot, stem decay, and damping-off (Rhizoctonia solani), sclerotinia stem decay (Sclerotinia sclerotiorum), sclerotinia southern blight (Sclerotinia rolfsii), thielaviopsis root rot (Thielaviopsis basicola).

Mycotoxins

In addition, the compound combination and the composition (formulation) of the invention may reduce the mycotoxin content in the harvested material and the foods and feeds prepared therefrom. Mycotoxins include particularly, but not exclusively, the following: deoxynivalenol (DON), nivalenol, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxin, fumonisins, zearalenon, moniliformin, fusarin, diaceotoxyscirpenol (DAS), beauvericin, enniatin, fusaroproliferin, fusarenol, ochratoxins, patulin, ergot alkaloids and aflatoxins which can be produced, for example, by the following fungi: Fusarium spec., such as F. acuminatum, F. asiaticum, F. avenaceum, F. crookwellense, F. culmorum, F. graminearum (Gibberella zeae), F. equiseti, F. fujikoroi, F. musarum, F. oxysporum, F. proliferatum, F. poae, F. pseudograminearum, F. sambucinum, F. scirpi, F. semitectum, F. solani, F. sporotrichoides, F. langsethiae, F. subglutinans, F. tricinctum, F. verticillioides, and also by Aspergillus spec., such as A. flavus, A. parasiticus, A. nomius, A. ochraceus, A. clavatus, A. terreus, A. versicolor, Penicillium spec., such as P. verrucosum, P. viridicatum, P. citrinum, P. expansum, P. claviforme, P. roqueforti, Claviceps spec., such as C. purpurea, C. fusiformis, C. paspali, C. africana, Stachybotrys spec, and others.

Formulations/Use forms

The present invention further relates to formulations, in particular formulations for controlling unwanted animal and microbial pests as well as unwanted microorganism. The formulation may be applied to the animal pest and microbial pest and unwanted microorganism and/or in their habitat. The formulation of the invention may be provided to the end user as “ready-for-use” use form, i.e. the formulations may be directly applied to the plants or seeds by a suitable device, such as a spraying or dusting device. Alternatively, the formulations may be provided to the end user in the form of concentrates which have to be diluted, preferably with water, prior to use. Unless otherwise indicated, the wording “formulation” therefore means such concentrate, whereas the wording “use form” means the end user as “ready-for-use” solution, i.e. usually such diluted formulation.

The formulation of the invention can be prepared in conventional manners, for example by mixing the active compound combination of the invention with one or more suitable auxiliaries, such as disclosed herein.

The formulation comprises at least one active compound combination of the invention and at least one agriculturally suitable auxiliary, e.g. carrier(s) and/or surfactant(s).

A carrier is a solid or liquid, natural or synthetic, organic or inorganic substance that is generally inert. The carrier generally improves the application of the compounds, for instance, to plants, plants parts or seeds. Examples of suitable solid carriers include, but are not limited to, ammonium salts, in particular ammonium sulfates, ammonium phosphates and ammonium nitrates, natural rock flours, such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite and diatomaceous earth, silica gel and synthetic rock flours, such as finely divided silica, alumina and silicates. Examples of typically useful solid carriers for preparing granules include, but are not limited to crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, synthetic granules of inorganic and organic flours and granules of organic material such as paper, sawdust, coconut shells, maize cobs and tobacco stalks. Examples of suitable liquid carriers include, but are not limited to, water, organic solvents and combinations thereof. Examples of suitable solvents include polar and nonpolar organic chemical liquids, for example from the classes of aromatic and nonaromatic hydrocarbons (such as cyclohexane, paraffins, alkylbenzenes, xylene, toluene, tetrahydronaphthalene, alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride), alcohols and polyols (which may optionally also be substituted, etherified and/or esterified, such as ethanol, propanol, butanol, benzylalcohol, cyclohexanol or glycol), ketones (such as acetone, methyl ethyl ketone, methyl isobutyl ketone, acetophenone, or cyclohexanone), esters (including fats and oils) and (poly)ethers, unsubstituted and substituted amines, amides (such as dimethylformamide or fatty acid amides) and esters thereof, lactams (such as N-alkylpyrrolidones, in particular N-methylpyrrolidone) and lactones, sulfones and sulfoxides (such as dimethyl sulfoxide), oils of vegetable or animal origin, nitriles (alkyl nitriles such as acetonitrile, propionotrilie, butyronitrile, or aromatic nitriles, such as benzonitrile), carbonic acid esters (cyclic carbonic acid esters, such as ethylene carbonate, propylene carbonate, butylene carbonate, or dialkyl carbonic acid esters, such as dimethyl carbonate, diethyl carbonate, dipropyl carbonate, dibutyl carbonate, dioctyl carbonate). The carrier may also be a liquefied gaseous extender, i.e. liquid which is gaseous at standard temperature and under standard pressure, for example aerosol propellants such as halohydrocarbons, butane, propane, nitrogen and carbon dioxide.

Preferred solid carriers are selected from clays, talc and silica.

Preferred liquid carriers are selected from water, fatty acid amides and esters thereof, aromatic and nonaromatic hydrocarbons, lactams, lactones, carbonic acid esters, ketones, (poly)ethers.

The amount of carrier typically ranges from 1 to 99.99%, preferably from 5 to 99.9%, more preferably from 10 to 99.5%, and most preferably from 20 to 99% by weight of the formulation.

Liquid carriers are typically present in a range of from 20 to 90%, for example 30 to 80% by weight of the formulation.

Solid carriers are typically present in a range of from 0 to 50%, preferably 5 to 45%, for example 10 to 30% by weight of the formulation.

If the formulation comprises two or more carriers, the outlined ranges refer to the total amount of carriers.

The surfactant can be an ionic (cationic or anionic), amphoteric or non-ionic surfactant, such as ionic or non-ionic emulsifier (s), foam former(s), dispersant(s), wetting agent(s), penetration enhancer(s) and any mixtures thereof. Examples of suitable surfactants include, but are not limited to, salts of polyacrylic acid, ethoxylated polya(alpha-substituted)acrylate derivatives, salts of lignosulfonic acid (such as sodium lignosulfonate), salts of phenolsulfonic acid or naphthalenesulfonic acid, polycondensates of ethylene oxide and/or propylene oxide with or without alcohols, fatty acids or fatty amines (for example, polyoxyethylene fatty acid esters such as castor oil ethoxylate, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers), substituted phenols (preferably alkylphenols or arylphenols), salts of sulfosuccinic esters, taurine derivatives (preferably alkyl taurates), phosphoric esters of polyethoxylated alcohols or phenols, fatty esters of polyols (such a fatty acid esters of glycerol, sorbitol or sucrose), sulfates (such as alkyl sulfates and alkyl ether sulfates), sulfonates (for example, alkylsulfonates, arylsulfonates and alkylbenzene sulfonates), sulfonated polymers of naphthalene/formaldehyde, phosphate esters, protein hydrolysates, lignosulfite waste liquors and methylcellulose. Any reference to salts in this paragraph refers preferably to the respective alkali, alkaline earth and ammonium salts.

Preferred surfactants are selected from ethoxylated polya(alpha-substituted)acrylate derivatives, polycondensates of ethylene oxide and/or propylene oxide with alcohols, polyoxyethylene fatty acid esters, alkylbenzene sulfonates, sulfonated polymers of naphthalene/formaldehyde, polyoxyethylene fatty acid esters such as castor oil ethoxylate, sodium lignosulfonate and arylphenol ethoxylate.

The amount of surfactants typically ranges from 5 to 40%, for example 10 to 20%, by weight of the formulation. Further examples of suitable auxiliaries include water repellents, siccatives, binders (adhesive, tackifier, fixing agent, such as carboxymethylcellulose, natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, natural phospholipids such as cephalins and lecithins and synthetic phospholipids, polyvinylpyrrolidone and tylose), thickeners and secondary thickeners (such as cellulose ethers, acrylic acid derivatives, xanthan gum, modified clays, e.g. the products available under the name Bentone, and finely divided silica), stabilizers (e.g. cold stabilizers, preservatives (e.g. dichlorophene, benzyl alcohol hemiformal, l,2-Benzisothiazolin-3-on, 2- methyl-4-isothiazolin-3-one), antioxidants, light stabilizers, in particular UV stabilizers, or other agents which improve chemical and/or physical stability), dyes or pigments (such as inorganic pigments, e.g. iron oxide, titanium oxide and Prussian Blue; organic dyes, e.g. alizarin, azo and metal phthalocyanine dyes), antifoams (e.g. silicone antifoams and magnesium stearate), antifreezes, stickers, gibberellins and processing auxiliaries, mineral and vegetable oils, perfumes, waxes, nutrients (including trace nutrients, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc), protective colloids, thixotropic substances, penetrants, sequestering agents and complex formers.

The choice of the auxiliaries depends on the intended mode of application of the active compound combination of the invention and/or on the physical properties of the compound(s). Furthermore, the auxiliaries may be chosen to impart particular properties (technical, physical and/or biological properties) to the formulations or use forms prepared therefrom. The choice of auxiliaries may allow customizing the formulations to specific needs.

The formulation comprises an insecticidal/fungicidal/acaricidal/nematicidal effective amount of the active compound combination of the invention. The term "effective amount" denotes an amount, which is sufficient for controlling harmful insects/mites/nematodes/fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the insect/mite/nematode/fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific active compound combination of the invention used. Usually, the formulation according to the invention contains from 0.01 to 99% by weight, preferably from 0.05 to 98% by weight, more preferred from 0.1 to 95% by weight, even more preferably from 0.5 to 90% by weight, most preferably from 1 to 80% by weight of the active compound combination of the invention. The outlined ranges refer to the total amount of active compound of formula (I) and active compounds of group (II) present in the active compound combination according to the invention.

The formulation of the invention may be in any customary formulation type, such as solutions (e.g aqueous solutions), emulsions, water- and oil-based suspensions, powders (e.g. wettable powders, soluble powders), dusts, pastes, granules (e.g. soluble granules, granules for broadcasting), suspoemulsion concentrates, natural or synthetic products impregnated with the active compound combination of the invention, fertilizers and also microencapsulations in polymeric substances. The active compound combination of the invention may be present in a suspended, emulsified or dissolved form. Examples of particular suitable formulation types are solutions, watersoluble concentrates (e.g. SL, LS), dispersible concentrates (DC), suspensions and suspension concentrates (e.g. SC, OD, OF, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME, SE), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GW, GF). These and further formulations types are defined by the Food and Agriculture Organization of the United Nations (FAO). An overview is given in the "Catalogue of pesticide formulation types and international coding system", Technical Monograph No. 2, 6th Ed. May 2008, Croplife International.

Preferably, the formulation of the invention is in form of one of the following types: EC, SC, FS, SE, OD, WG, WP, CS, more preferred EC, SC, OD, WG, CS.

The outlined amounts of active compound combination according to the invention in the examples of formulation types and their preparation given below refer to the total amount of active compound of formula (I) and active compounds of group (II) present in the active compound combination according to the invention. This applies mutatis mutandis for any further component of the formulation, if two or more representatives of such component, e.g. surfactant, wetting agent, binder, are present. i) Water-soluble concentrates (SL, LS)

10-60 % by weight of the active compound combination according to the invention and 5-15 % by weight surfactant (e.g. polycondensates of ethylene oxide and/or propylene oxide with alcohols) are dissolved in such amount of water and/or water-soluble solvent (e.g. alcohols such as propylene glycol or carbonates such as propylene carbonate) to result in a total amount of 100 % by weight. Before application the concentrate is diluted with water. ii) Dispersible concentrates (DC)

5-25 % by weight of the active compound combination according to the invention and 1-10 % by weight surfactant and/or binder (e.g. polyvinylpyrrolidone) are dissolved in such amount of organic solvent (e.g. cyclohexanone) to result in a total amount of 100 % by weight. Dilution with water gives a dispersion. iii) Emulsifiable concentrates (EC)

15-70 % by weight of the active compound combination according to the invention and 5-10 % by weight surfactant (e.g. a mixture of calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in such amount of water-insoluble organic solvent (e.g. aromatic hydrocarbon or fatty acid amide) and if needed additional water-soluble solvent to result in a total amount of 100 % by weight. Dilution with water gives an emulsion. iv) Emulsions (EW, EO, ES)

5-40 % by weight of the active compound combination according to the invention and 1-10 % by weight surfactant (e.g. a mixture of calcium dodecylbenzenesulfonate and castor oil ethoxylate, or polycondensates of ethylene oxide and/or propylene oxide with or without alcohols) are dissolved in 20- 40 % by weight water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is added to such amount of water by means of an emulsifying machine to result in a total amount of 100 % by weight. The resulting formulation is a homogeneous emulsion. Before application the emulsion may be further diluted with water. v) Suspensions and suspension concentrates v-1) Water-based (SC, FS)

In a suitable grinding equipment, e.g. an agitated ball mill, 20-60 % by weight of the active compound combination according to the invention are comminuted with addition of 2-10 % by weight surfactant (e.g. sodium lignosulfonate and polyoxyethylene fatty alcohol ether), 0.1-2 % by weight thickener (e.g. xanthan gum) and water to give a fine active substance suspension. The water is added in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable suspension of the active substances. For FS type formulations up to 40 % by weight binder (e.g. polyvinylalcohol) is added. v-2) Oil-based (OD, OF)

In a suitable grinding equipment, e.g. an agitated ball mill, 20-60 % by weight of the active compound combination according to the invention of the invention are comminuted with addition of 2-10 % by weight surfactant (e.g. sodium lignosulfonate and polyoxyethylene fatty alcohol ether), 0.1-2 % by weight thickener (e.g. modified clay, in particular Bentone, or silica) and an organic carrier to give a fine active substance oil suspension. The organic carrier is added in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion of the active substances. vi) Water-dispersible granules and water-soluble granules (WG, SG)

1-90 % by weight, preferably 20-80%, most preferably 50-80 % by weight of the active compound combination according to the invention are ground finely with addition of surfactant (e.g. sodium lignosulfonate and sodium alkylnaphthylsulfonates) and potentially carrier material and converted to water-dispersible or water-soluble granules by means of typical technical appliances like e.g. extrusion, spray drying, fluidized bed granulation. The surfactant and carrier material are used in such amount to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion or solution of the active substances. vii) Water-dispersible powders and water-soluble powders (WP, SP, WS) 50-80 % by weight of the active compound combination according to the invention are ground in a rotorstator mill with addition of 1-20 % by weight surfactant (e.g. sodium lignosulfonate, sodium alkylnaphthylsulfonates) and such amount of solid carrier, e.g. silica gel, to result in a total amount of 100 % by weight. Dilution with water gives a stable dispersion or solution of the active substances. viii) Gel (GW, GF)

In an agitated ball mill, 5-25 % by weight of the active compound combination according to the invention are comminuted with addition of 3-10 % by weight surfactant (e.g. sodium lignosulfonate), 1-5 % by weight binder (e.g. carboxymethylcellulose) and such amount of water to result in a total amount of 100 % by weight. This results in a fine suspension of the active substances. Dilution with water gives a stable suspension of the active substances. ix) Microemulsion (ME)

5-20 % by weight of the active compound combination according to the invention are added to 5-30 % by weight organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 % by weight surfactant blend (e.g. polyoxyethylene fatty alcohol ether and arylphenol ethoxylate), and such amount of water to result in a total amount of 100 % by weight. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion. x) Microcapsules (CS)

An oil phase comprising 5-50 % by weight of the active compound combination according to the invention, 0-40 % by weight water-insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 % by weight acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 % by weight of the active compound combination according to the invention, 0- 40 % by weight water-insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylmethene-4,4'-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol), this resulting in the formation of polyurea microcapsules. Optionally, the addition of a polyamine (e.g. hexamethylenediamine) is also used to result in the formation of polyurea microcapsules. The monomers amount to 1-10 % by weight of the total CS formulation. xi) Dustable powders (DP, DS)

1-10 % by weight of the active compound combination according to the invention are ground finely and mixed intimately with such amount of solid carrier, e.g. finely divided kaolin, to result in a total amount of 100 % by weight. xii) Granules (GR, FG)

0.5-30 % by weight of the active compound combination according to the invention are ground finely and associated with such amount of solid carrier (e.g. silicate) to result in a total amount of 100 % by weight. xiii) Ultra-low volume liquids (UL)

1-50 % by weight of the active compound combination according to the invention are dissolved in such amount of organic solvent, e.g. aromatic hydrocarbon, to result in a total amount of 100 % by weight.

The formulations types i) to xiii) may optionally comprise further auxiliaries, such as 0.1-1 % by weight preservatives, 0.1-1 % by weight antifoams, 0.1-1 % by weight dyes and/or pigments, and 5-10% by weight antifreezes.

Plants and plant parts

All plants and plant parts can be treated in accordance with the invention. Here, plants are to be understood to mean all plants and plant parts such as wanted and unwanted wild plants or crop plants (including naturally occurring crop plants), for example cereals (wheat, rice, triticale, barley, rye, oats), maize, soya bean, potato, sugar beet, sugar cane, tomatoes, pepper, cucumber, melon, carrot, watermelon, onion, lettuce, spinach, leek, beans, Brassica oleracea (e.g. cabbage) and other vegetable species, cotton, tobacco, oilseed rape, and also fruit plants (with the fruits apples, pears, citrus fruits and grapevines). Crop plants can be plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of these methods, including the transgenic plants and including the plant varieties which can or cannot be protected by varietal property rights. Plants should be understood to mean all developmental stages, such as seeds, seedlings, young (immature) plants up to mature plants. Plant parts should be understood to mean all parts and organs of the plants above and below ground, such as shoot, leaf, flower and root, examples given being leaves, needles, stalks, stems, flowers, fruit bodies, fruits and seeds, and also tubers, roots and rhizomes. Parts of plants also include harvested plants or harvested plant parts and vegetative and generative propagation material, for example seedlings, tubers, rhizomes, cuttings and seeds.

Treatment according to the invention of the plants and plant parts with the active compound combination according to the invention is carried out directly or by allowing the compounds to act on the surroundings, environment or storage space by the customary treatment methods, for example by immersion, spraying, evaporation, fogging, scattering, painting on, injection and, in the case of propagation material, in particular in the case of seeds, also by applying one or more coats.

As already mentioned above, it is possible to treat all plants and their parts according to the invention. In a preferred embodiment, wild plant species and plant cultivars, or those obtained by conventional biological breeding methods, such as crossing or protoplast fusion, and also parts thereof, are treated. In a further preferred embodiment, transgenic plants and plant cultivars obtained by genetic engineering methods, if appropriate in combination with conventional methods (genetically modified organisms), and parts thereof are treated. The term “parts” or “parts of plants” or “plant parts” has been explained above. The invention is used with particular preference to treat plants of the respective commercially customary cultivars or those that are in use. Plant cultivars are to be understood as meaning plants having new properties ("traits") and which have been obtained by conventional breeding, by mutagenesis or by recombinant DNA techniques. They can be cultivars, varieties, bio- or genotypes.

Transgenic plant, seed treatment and integration events

According to the invention, the active compound combination according to the invention can be advantageously used to treat transgenic plants, plant cultivars or plant parts that received genetic material which imparts advantageous and/or useful properties (traits) to these plants, plant cultivars or plant parts. Therefore, it is contemplated that the present invention may be combined with one or more recombinant traits or transgenic event(s) or a combination thereof. For the purposes of this application, a transgenic event is created by the insertion of a specific recombinant DNA molecule into a specific position (locus) within the chromosome of the plant genome. The insertion creates a novel DNA sequence referred to as an “event” and is characterized by the inserted recombinant DNA molecule and some amount of genomic DNA immediately adjacent to/flanking both ends of the inserted DNA. Such trait(s) or transgenic event(s) include, but are not limited to, pest resistance, water use efficiency, yield performance, drought tolerance, seed quality, improved nutritional quality, hybrid seed production, and herbicide tolerance, in which the trait is measured with respect to a plant lacking such trait or transgenic event. Concrete examples of such advantageous and/or useful properties (traits) are better plant growth, vigor, stress tolerance, standability, lodging resistance, nutrient uptake, plant nutrition, and/or yield, in particular improved growth, increased tolerance to high or low temperatures, increased tolerance to drought or to levels of water or soil salinity, enhanced flowering performance, easier harvesting, accelerated ripening, higher yields, higher quality and/or a higher nutritional value of the harvested products, better storage life and/or processability of the harvested products, and increased resistance or tolerance against animal and microbial pests, such as against insects, arachnids, nematodes, mites, slugs and snails.

Among DNA sequences encoding proteins which confer properties of resistance or tolerance to such animal and microbial pests, in particular insects, mention will particularly be made of the genetic material from Bacillus thuringiensis encoding the Bt proteins widely described in the literature and well known to those skilled in the art. Mention will also be made of proteins extracted from bacteria such as Photorhabdus (WO97/17432 and WO98/08932). In particular, mention will be made of the Bt Cry or VIP proteins which include the CrylA, CrylAb, CrylAc, CryllA, CrylllA, CryIIIB2, Cry9c Cry2Ab, Cry3Bb and CrylF proteins or toxic fragments thereof and also hybrids or combinations thereof, especially the CrylF protein or hybrids derived from a CrylF protein (e.g. hybrid CrylA-CrylF proteins or toxic fragments thereof), the CrylA-type proteins or toxic fragments thereof, preferably the CrylAc protein or hybrids derived from the CrylAc protein (e.g. hybrid CrylAb-CrylAc proteins) or the CrylAb or Bt2 protein or toxic fragments thereof, the Cry2Ae, Cry2Af or Cry2Ag proteins or toxic fragments thereof, the CrylA.105 protein or a toxic fragment thereof, the VIP3Aal9 protein, the VIP3Aa20 protein, the VIP3A proteins produced in the COT202 or COT203 cotton events, the VIP3Aa protein ora toxic fragment thereof as described in Estruch et al. (1996), Proc Natl Acad Sci US A. 28;93(l l):5389-94, the Cry proteins as described in WO2001/47952, the insecticidal proteins from Xenorhabdus (as described in WO98/50427), Serratia (particularly from S. entomophila) or Photorhabdus species strains, such as Tc-proteins from Photorhabdus as described in WO98/08932. Also any variants or mutants of any one of these proteins differing in some amino acids (1-10, preferably 1-5) from any of the above named sequences, particularly the sequence of their toxic fragment, or which are fused to a transit peptide, such as a plastid transit peptide, or another protein or peptide, is included herein.

Another and particularly emphasized example of such properties is conferred tolerance to one or more herbicides, for example imidazolinones, sulphonylureas, glyphosate or phosphinothricin. Among DNA sequences encoding proteins which confer properties of tolerance to certain herbicides on the transformed plant cells and plants, mention will be particularly be made to the bar or PAT gene or the Streptomyces coelicolor gene described in WO2009/152359 which confers tolerance to glufosinate herbicides, a gene encoding a suitable EPSPS (5-enolpyruvylshikimat-3-phosphat-synthase) which confers tolerance to herbicides having EPSPS as a target, especially herbicides such as glyphosate and its salts, a gene encoding glyphosate-n-acetyltransferase, or a gene encoding glyphosate oxidoreductase. Further suitable herbicide tolerance traits include at least one ALS (acetolactate synthase) inhibitor (e.g. W02007/024782), a mutated Arabidopsis ALS/AHAS gene (e.g. U.S. Patent 6,855,533), genes encoding 2,4-D- monooxygenases conferring tolerance to 2,4-D (2,4- dichlorophenoxyacetic acid) and genes encoding Dicamba monooxygenases conferring tolerance to dicamba (3,6-dichloro-2- methoxybenzoic acid).

Yet another example of such properties is resistance to one or more phytopathogenic fungi, for example Asian Soybean Rust. Among DNA sequences encoding proteins which confer properties of resistance to such diseases, mention will particularly be made of the genetic material from glycine tomentella, for example from any one of publically available accession lines PI441001 , PI483224, PI583970, PI446958, PI499939, PI505220, PI499933, PI441008, PI505256 or PI446961 as described in W02019/103918.

Further and particularly emphasized examples of such properties are increased resistance against phytopathogenic fungi, bacteria and/or viruses owing, for example, to systemic acquired resistance (SAR), systemin, phytoalexins, elicitors and also resistance genes and correspondingly expressed proteins and toxins.

Particularly useful transgenic events in transgenic plants or plant cultivars which can be treated with preference in accordance with the invention include Event 531/ PV-GHBK04 (cotton, insect control, described in W02002/040677), Event 1143-14A (cotton, insect control, not deposited, described in WO2006/128569); Event 1143-51B (cotton, insect control, not deposited, described in W02006/128570); Event 1445 (cotton, herbicide tolerance, not deposited, described in US-A 2002- 120964 or W02002/034946); Event 17053 (rice, herbicide tolerance, deposited as PTA-9843, described in WO2010/117737); Event 17314 (rice, herbicide tolerance, deposited as PTA-9844, described in WO2010/117735); Event 281-24-236 (cotton, insect control - herbicide tolerance, deposited as PTA-6233, described in W02005/103266 or US-A 2005-216969); Event 3006-210-23 (cotton, insect control - herbicide tolerance, deposited as PTA-6233, described in US-A 2007-143876 orW02005/103266); Event 3272 (corn, quality trait, deposited as PTA-9972, described in W02006/098952 or US-A 2006-230473); Event 33391 (wheat, herbicide tolerance, deposited as PTA-2347, described in W02002/027004), Event 40416 (corn, insect control - herbicide tolerance, deposited as ATCC PTA-11508, described in WO 11/075593); Event 43A47 (corn, insect control - herbicide tolerance, deposited as ATCC PTA-11509, described in WO2011/075595); Event 5307 (corn, insect control, deposited as ATCC PTA-9561, described in W02010/077816); Event ASR- 368 (bent grass, herbicide tolerance, deposited as ATCC PTA-4816, described in US-A 2006-162007 or W02004/053062); Event B16 (corn, herbicide tolerance, not deposited, described in US-A 2003- 126634); Event BPS-CV127- 9 (soybean, herbicide tolerance, deposited as NCIMB No. 41603, described in WO2010/080829); Event BLR1 (oilseed rape, restoration of male sterility, deposited as NCIMB 41193, described in W02005/074671), Event CE43-67B (cotton, insect control, deposited as DSM ACC2724, described in US-A 2009-217423 or WO2006/128573); Event CE44-69D (cotton, insect control, not deposited, described in US-A 2010- 0024077); Event CE44-69D (cotton, insect control, not deposited, described in WO2006/128571); Event CE46-02A (cotton, insect control, not deposited, described in WO2006/128572); Event COT102 (cotton, insect control, not deposited, described in US-A 2006-130175 or W02004/039986); Event COT202 (cotton, insect control, not deposited, described in US-A 2007-067868 or W02005/054479); Event COT203 (cotton, insect control, not deposited, described in W02005/054480); ); Event DAS21606-3 / 1606 (soybean, herbicide tolerance, deposited as PTA-11028, described in WO2012/033794), Event DAS40278 (corn, herbicide tolerance, deposited as ATCC PTA-10244, described in WO2011/022469); Event DAS-44406-6 / pDAB8264.44.06.1 (soybean, herbicide tolerance, deposited as PTA-11336, described in WO2012/075426), Event DAS-14536-7 /pDAB8291.45.36.2 (soybean, herbicide tolerance, deposited as PTA-11335, described in WO2012/075429), Event DAS-59122-7 (corn, insect control - herbicide tolerance, deposited as ATCC PTA 11384, described in US-A 2006- 070139); Event DAS-59132 (corn, insect control - herbicide tolerance, not deposited, described in W02009/100188); Event DAS68416 (soybean, herbicide tolerance, deposited as ATCC PTA-10442, described in WO2011/066384 or WO2011/066360); Event DP-098140-6 (corn, herbicide tolerance, deposited as ATCC PTA-8296, described in US-A 2009- 137395 or WO 08/112019); Event DP- 305423-1 (soybean, quality trait, not deposited, described in US-A 2008-312082 or W02008/054747); Event DP-32138-1 (corn, hybridization system, deposited as ATCC PTA-9158, described in US-A 2009-0210970 or W02009/103049); Event DP-356043-5 (soybean, herbicide tolerance, deposited as ATCC PTA-8287, described in US-A 2010-0184079 or W02008/002872); EventEE-I (brinjal, insect control, not deposited, described in WO 07/091277); Event Fil 17 (corn, herbicide tolerance, deposited as ATCC 209031, described in US-A 2006-059581 or WO 98/044140); Event FG72 (soybean, herbicide tolerance, deposited as PTA-11041, described in WO2011/063413), Event GA21 (corn, herbicide tolerance, deposited as ATCC 209033, described in US-A 2005-086719 or WO 98/044140); Event GG25 (corn, herbicide tolerance, deposited as ATCC 209032, described in US-A 2005-188434 or WO98/044140); Event GHB 119 (cotton, insect control - herbicide tolerance, deposited as ATCC PTA-8398, described in W02008/151780); Event GHB614 (cotton, herbicide tolerance, deposited as ATCC PTA-6878, described in US-A 2010-050282 or W02007/017186); Event GJ11 (corn, herbicide tolerance, deposited as ATCC 209030, described in US-A 2005-188434 or W098/044140); Event GM RZ13 (sugar beet, virus resistance, deposited as NCIMB-41601, described in W02010/076212); Event H7-1 (sugar beet, herbicide tolerance, deposited as NCIMB 41158 or NCIMB 41159, described in US-A 2004-172669 or WO 2004/074492); Event JOPLIN1 (wheat, disease tolerance, not deposited, described in US-A 2008-064032); Event LL27 (soybean, herbicide tolerance, deposited as NCIMB41658, described in W02006/108674 or US-A 2008- 320616); Event LL55 (soybean, herbicide tolerance, deposited as NCIMB 41660, described in WO 2006/108675 or US-A 2008-196127); Event LLcotton25 (cotton, herbicide tolerance, deposited as ATCC PTA-3343, described in W02003/013224 or US- A 2003-097687); Event LLRICE06 (rice, herbicide tolerance, deposited as ATCC 203353, described in US 6,468,747 or W02000/026345); Event LLRice62 (rice, herbicide tolerance, deposited as ATCC 203352, described in W02000/026345), Event LLRICE601 (rice, herbicide tolerance, deposited as ATCC PTA-2600, described in US-A 2008-2289060 or W02000/026356); Event LYO38 (corn, quality trait, deposited as ATCC PTA-5623, described in US-A 2007-028322 or W02005/061720); Event MIR162 (corn, insect control, deposited as PTA-8166, described in US-A 2009-300784 or W02007/142840); Event MIR604 (corn, insect control, not deposited, described in US-A 2008-167456 or W02005/103301); Event MON15985 (cotton, insect control, deposited as ATCC PTA-2516, described in US-A 2004- 250317 or W02002/100163); Event MON810 (corn, insect control, not deposited, described in US- A 2002-102582); Event MON863 (corn, insect control, deposited as ATCC PTA-2605, described in W02004/011601 or US-A 2006-095986); Event MON87427 (corn, pollination control, deposited as ATCC PTA-7899, described in WO2011/062904); Event MON87460 (corn, stress tolerance, deposited as ATCC PTA-8910, described in W02009/111263 or US-A 2011-0138504); Event MON87701 (soybean, insect control, deposited as ATCC PT A- 8194, described in US-A 2009- 130071 or W02009/064652); Event MON87705 (soybean, quality trait - herbicide tolerance, deposited as ATCC PTA-9241, described in US-A 2010-0080887 or W02010/037016); Event MON87708 (soybean, herbicide tolerance, deposited as ATCC PTA-9670, described in WO2011/034704); Event MON87712 (soybean, yield, deposited as PTA-10296, described in WO20 12/051199), Event MON87754 (soybean, quality trait, deposited as ATCC PTA-9385, described in WO2010/024976); Event MON87769 (soybean, quality trait, deposited as ATCC PTA- 8911, described in US-A 2011-0067141 or W02009/102873); Event MON88017 (corn, insect control - herbicide tolerance, deposited as ATCC PTA-5582, described in US-A 2008-028482 or W02005/059103); Event MON88913 (cotton, herbicide tolerance, deposited as ATCC PTA-4854, described in W02004/072235 or US-A 2006-059590); Event MON88302 (oilseed rape, herbicide tolerance, deposited as PTA-10955, described in WO2011/153186), Event MON88701 (cotton, herbicide tolerance, deposited as PTA-11754, described in WO2012/134808), Event MON89034 (corn, insect control, deposited as ATCC PTA-7455, described in WO 07/140256 or US-A 2008- 260932); Event MON89788 (soybean, herbicide tolerance, deposited as ATCC PTA-6708, described in US-A 2006-282915 or W02006/130436); Event MSI 1 (oilseed rape, pollination control - herbicide tolerance, deposited as ATCC PTA-850 or PTA-2485, described in WO2001/031042); Event MS8 (oilseed rape, pollination control - herbicide tolerance, deposited as ATCC PTA-730, described in W02001/041558 or US-A 2003-188347); Event NK603 (corn, herbicide tolerance, deposited as ATCC PTA-2478, described in US-A 2007-292854); Event PE-7 (rice, insect control, not deposited, described in W02008/114282); Event RF3 (oilseed rape, pollination control - herbicide tolerance, deposited as ATCC PTA-730, described in W02001/041558 or US-A 2003-188347); Event RT73 (oilseed rape, herbicide tolerance, not deposited, described in W02002/036831 or US-A 2008- 070260); Event SYHT0H2 / SYN-000H2-5 (soybean, herbicide tolerance, deposited as PTA-11226, described in WO2012/082548), Event T227-1 (sugar beet, herbicide tolerance, not deposited, described in W02002/44407 or US-A 2009-265817); Event T25 (corn, herbicide tolerance, not deposited, described in US-A 2001-029014 or W02001/051654); Event T304-40 (cotton, insect control - herbicide tolerance, deposited as ATCC PTA-8171, described in US-A 2010-077501 or W02008/ 122406); Event T342-142 (cotton, insect control, not deposited, described in WO2006/128568); Event TC1507 (corn, insect control - herbicide tolerance, not deposited, described in US-A 2005-039226 or W02004/099447); Event VIP1034 (corn, insect control - herbicide tolerance, deposited as ATCC PTA-3925, described in W02003/052073), Event 32316 (corn, insect control-herbicide tolerance, deposited as PTA-11507, described in WO2011/084632), Event 4114 (corn, insect control-herbicide tolerance, deposited as PTA-11506, described in W02011/084621), event EE-GM3 / FG72 (soybean, herbicide tolerance, ATCC Accession N° PTA-11041) optionally stacked with event EE-GM1/LL27 or event EE-GM2/LL55 (WO2011/063413A2), event DAS- 68416-4 (soybean, herbicide tolerance, ATCC Accession N° PTA-10442, W02011/066360A1), event DAS-68416-4 (soybean, herbicide tolerance, ATCC Accession N° PTA-10442, WO2011/066384A1), event DP-040416-8 (corn, insect control, ATCC Accession N° PTA-11508, WO2011/075593 Al), event DP-043 A47-3 (corn, insect control, ATCC Accession N° PTA-11509, WO2011/075595A1), event DP- 004114-3 (corn, insect control, ATCC Accession N° PTA-11506, WO2011/084621 Al), event DP-032316-8 (corn, insect control, ATCC Accession N° PTA-11507, WO2011/084632A1), event MON-88302-9 (oilseed rape, herbicide tolerance, ATCC Accession N° PTA-10955, WO2011/153186A1), event DAS-21606-3 (soybean, herbicide tolerance, ATCC Accession No. PTA-11028, WO2012/033794A2), event MON-87712-4 (soybean, quality trait, ATCC Accession N°. PTA-10296, WO2012/051199 A2), event DAS-44406-6 (soybean, stacked herbicide tolerance, ATCC Accession N°. PTA-11336, WO2012/075426A1), event DAS-14536-7 (soybean, stacked herbicide tolerance, ATCC Accession N°. PTA-11335, WO2012/075429 Al), event SYN-000H2-5 (soybean, herbicide tolerance, ATCC Accession N°. PTA-11226, WO2012/082548A2), event DP-061061-7 (oilseed rape, herbicide tolerance, no deposit N° available, W02012071039A1), event DP-073496-4 (oilseed rape, herbicide tolerance, no deposit N° available, US2012131692), event 8264.44.06.1 (soybean, stacked herbicide tolerance, Accession N° PTA- 11336, WO2012075426A2), event 8291.45.36.2 (soybean, stacked herbicide tolerance, Accession N°. PTA-11335, WO2012075429A2), event SYHT0H2 (soybean, ATCC Accession N°. PTA-11226, WO2012/082548A2), event MON88701 (cotton, ATCC Accession N° PTA-11754,

WO2012/134808A1), event KK179-2 (alfalfa, ATCC Accession N° PTA-11833,

W02013/003558A1), event pDAB8264.42.32.1 (soybean, stacked herbicide tolerance, ATCC Accession N° PTA-11993, WO2013/010094 Al), event MZDT09Y (corn, ATCC Accession N° PTA- 13025, WO2013/012775A1).

Further, a list of such transgenic event(s) is provided by the United States Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) and can be found on their website at https://www.aphis.usda.gov/. For this application, the status of such list as it is/was on the filing date of this application, is relevant.

The genes/events which impart the desired traits in question may also be present in combinations with one another in the transgenic plants. Examples of transgenic plants which may be mentioned are the important crop plants, such as cereals (wheat, rice, triticale, barley, rye, oats), maize, soya beans, potatoes, sugar beet, sugar cane, tomatoes, peas and other types of vegetable, cotton, tobacco, oilseed rape and also fruit plants (with the fruits apples, pears, citrus fruits and grapes), with particular emphasis being given to maize, soya beans, wheat, rice, potatoes, cotton, sugar cane, tobacco and oilseed rape. Traits which are particularly emphasized are the increased resistance of the plants to insects, arachnids, nematodes and slugs and snails, as well as the increased resistance of the plants to one or more herbicides.

Commercially available examples of such plants, plant parts or plant seeds that may be treated with preference in accordance with the invention include commercial products, such as plant seeds, sold or distributed under the GENUITY®, DROUGHTGARD®, SMARTSTAX®, RIB COMPLETE®, ROUNDUP READY®, VT DOUBLE PRO®, VT TRIPLE PRO®, BOLLGARD II®, ROUNDUP READY 2 YIELD®, YIELDGARD®, ROUNDUP READY® 2 XTEN^D™, INTACTA RR2 PRO®, VISTIVE GOLD®, and/or XTENDFLEX™ trade names.

Crop protection - types of treatment

The treatment of the plants and plant parts with the active compound combination according to the invention is carried out directly or by action on their surroundings, habitat or storage space using customary treatment methods, for example by dipping, spraying, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, foaming, painting, spreading-on, injecting, watering (drenching), drip irrigating and, in the case of propagation material, in particular in the case of seed, furthermore as a powder for dry seed treatment, a solution for liquid seed treatment, a water-soluble powder for slurry treatment, by incrusting, by coating with one or more coats, etc. It is furthermore possible to apply the active compound combination according to the invention by the ultra-low volume method or to inject the application form or the active compound combination according to the invention itself into the soil.

A preferred direct treatment of the plants is foliar application, i.e. the active compound combination according to the invention is applied to the foliage, where treatment frequency and the application rate should be adjusted according to the level of infestation with the pest in question.

In the case of systemically active compounds, the active compound combination according to the invention also access the plants via the root system. The plants are then treated by the action of the active compound combination according to the invention on the habitat of the plant. This may be done, for example, by drenching, or by mixing into the soil or the nutrient solution, i.e. the locus of the plant (e.g. soil or hydroponic systems) is impregnated with a liquid form of the active compound combination according to the invention, or by soil application, i.e. the active compound combination according to the invention is introduced in solid form (e.g. in the form of granules) into the locus of the plants, or by drip application (often also referred to as "chemigation"), i.e. the liquid application of the active compound combination according to the invention from surface or sub-surface driplines over a certain period of time together with varying amounts of water at defined locations in the vicinity of the plants. In the case of paddy rice crops, this can also be done by metering the active compound combination according to the invention in a solid application form (for example as granules) into a flooded paddy field.

Digital Technologies

The active compound combination of the invention can be used in combination with models e.g. embedded in computer programs for site specific crop management, satellite farming, precision farming or precision agriculture. Such models support the site specific management of agricultural sites with data from various sources such as soils, weather, crops (e.g. type, growth stage, plant health), weeds (e.g. type, growth stage), diseases, pests, nutrients, water, moisture, biomass, satellite data, yield etc. with the purpose to optimize profitability, sustainability and protection of the environment. In particular, such models can help to optimize agronomical decisions, control the precision of pesticide/fungicide applications and record the work performed.

As an example, the active compound combination of the invention can be applied to a crop plant according to an appropriate dose regime if a model models the development of a pest and calculates that a threshold has been reached for which it is recommendable to apply the active compound combination of the invention to the crop plant. Commercially available systems which include agronomic models are e.g. FieldScriptsTM from The Climate Corporation, XarvioTM from BASF, AGLogicTM from John Deere, etc.

The active compound combination of the invention can also be used in combination with smart spraying equipment such as e.g. spot spraying or precision spraying equipment attached to or housed within a farm vehicle such as a tractor, robot, helicopter, airplane, unmanned aerial vehicle (UAV) such as a drone, etc. Such an equipment usually includes input sensors (such as e.g. a camera) and a processing unit configured to analyze the input data and configured to provide a decision based on the analysis of the input data to apply the active compound combination of the invention to the crop plants (respectively the weeds) in a specific and precise manner. The use of such smart spraying equipment usually also requires positions systems (e.g. GPS receivers) to localize recorded data and to guide or to control farm vehicles; geographic information systems (GIS) to represent the information on intelligible maps, and appropriate farm vehicles to perform the required farm action such as the spraying.

In an example, pests can be detected from imagery acquired by a camera. In an example the pests can be identified and/or classified based on that imagery. Such identification and/ classification can make use of image processing algorithms. Such image processing algorithms can utilize machine learning algorithms, such as trained neutral networks, decision trees and utilize artificial intelligence algorithms. In this manner, the active compound combination according to the invention can be applied only where needed.

Treatment of seed

The control of animal and mircorbial pests as well as unwanted microorganism by treating the seed of plants has been known for a long time and is the subject of continuous improvements. However, the treatment of seed entails a series of problems which cannot always be solved in a satisfactory manner. Thus, it is desirable to develop methods for protecting the seed and the germinating plant which dispense with, or at least reduce considerably, the additional application of pesticides/fungicides during storage, after sowing or after emergence of the plants. It is furthermore desirable to optimize the amount of active compound employed in such a way as to provide optimum protection for the seed and the germinating plant from attack by animal and microbial pests as well as by unwanted microorganism, but without damaging the plant itself by the active compound employed. In particular, methods for the treatment of seed should also take into consideration the intrinsic insecticidal or nematicidal properties of pest-resistant or -tolerant transgenic plants in order to achieve optimum protection of the seed and also the germinating plant with a minimum of pesticides being employed.

The present invention therefore in particular also relates to a method for the protection of seed and germinating plants, from attack by pests or from unwanted microorgansim, by treating the seed with an active compound combination according to the invention. The method according to the invention for protecting seed and germinating plants against attack by pests or from unwanted microorganism furthermore comprises a method where the seed is treated simultaneously in one operation or sequentially with the compound of formula (I) and a mixing partner of group (II). It also comprises a method where the seed is treated at different times with a compound of the formula (I) and a mixing partner of group (II).

The invention likewise relates to the use of the active compound combination according to the invention for the treatment of seed for protecting the seed and the resulting plant from animal and microbial pests as well as unwanted microorganism.

Furthermore, the invention relates to seed which has been treated with an active compound combination according to the invention so as to afford protection from animal and microbial pests as well as unwanted microorganism. The invention also relates to seed which has been treated simultaneously with a compound of the formula (I) and a mixing partner of group (II). The invention furthermore relates to seed which has been treated at different times with a compound of the formula (I) and a mixing partner of group (II). In the case of seed which has been treated at different points in time with a compound of the formula (I) and a mixing partner of group (II), the individual substances may be present on the seed in different layers. Here, the layers comprising a compound of the formula (I) and mixing partner of group (II) may optionally be separated by an intermediate layer. The invention also relates to seed where a compound of the formula (I) and a mixing partner of group (II) have been applied as component of a coating or as a further layer or further layers in addition to a coating.

Furthermore, the invention relates to seed which, after the treatment with an active compound combination according to the invention, is subjected to a film-coating process to prevent dust abrasion on the seed.

One of the advantages encountered with a systemically acting active compound combination according to the invention is the fact that, by treating the seed, not only the seed itself but also the plants resulting therefrom are, after emergence, protected against animal and microbial pests as well as unwanted microorganism. In this manner, the immediate treatment of the crop at the time of sowing or shortly thereafter can be dispensed with.

It has to be considered a further advantage that by treatment of the seed with an active compound combination according to the invention, germination and emergence of the treated seed may be enhanced.

It is likewise to be considered advantageous that an active compound combination according to the invention can be used in particular also for transgenic seed.

Furthermore, active compound combinations according to the invention can be employed in combination with compositions or compounds of signalling technology, leading to better colonization by symbionts such as, for example, rhizobia, mycorrhizae and/or endophytic bacteria or, and/or to optimized nitrogen fixation. The active compound combinations according to the invention are suitable for protection of seed of any plant variety which is used in agriculture, in the greenhouse, in forests or in horticulture. In particular, this takes the form of seed of cereals (for example wheat, barley, rye, millet and oats), corn, cotton, soya beans, rice, potatoes, sunflowers, coffee, tobacco, canola, oilseed rape, beets (for example sugarbeets and fodder beets), peanuts, vegetables (for example tomatoes, cucumbers, bean, cruciferous vegetables, onions and lettuce), fruit plants, lawns and ornamental plants. The treatment of the seed of cereals (such as wheat, barley, rye and oats), maize, soya beans, cotton, canola, oilseed rape, vegetables and rice is of particular importance.

As already mentioned above, the treatment of transgenic seed with an active compound combination according to the invention is also of particular importance. This takes the form of seed of plants which, as a rule, comprise at least one heterologous gene which governs the expression of a polypeptide with in particular insecticidal and/or nematicidal properties. The heterologous genes in transgenic seed can originate from microorganisms such as Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, Clavibacter, Glomus or Gliocladium. The present invention is particularly suitable for the treatment of transgenic seed which comprises at least one heterologous gene originating from Bacillus sp. It is particularly preferably a heterologous gene derived from Bacillus thuringiensis.

In the context of the present invention, the active compound combination according to the invention is applied to the seed. Preferably, the seed is treated in a state in which it is stable enough to avoid damage during treatment. In general, the seed may be treated at any point in time between harvest and sowing. The seed usually used has been separated from the plant and freed from cobs, shells, stalks, coats, hairs or the flesh of the fruits. For example, it is possible to use seed which has been harvested, cleaned and dried down to a moisture content which allows storage. Alternatively, it is also possible to use seed which, after drying, has been treated with, for example, water and then dried again, for example priming. In the case of rice seed, it is also possible to use seed which has been soaked, for example in water to a certain stage of the rice embryo (‘pigeon breast stage’), stimulating the germination and a more uniform emergence.

When treating the seed, care must generally be taken that the amount of the active compound combination according to the invention applied to the seed and/or the amount of further additives is chosen in such a way that the germination of the seed is not adversely affected, or that the resulting plant is not damaged. This must be ensured particularly in the case of active compounds which can exhibit phytotoxic effects at certain application rates.

In general, the active compound combinations according to the invention are applied to the seed in a suitable formulation. Suitable formulations and processes for seed treatment are known to the person skilled in the art. The active compound combinations according to the invention can be converted to the customary seed dressing formulations, such as solutions, emulsions, suspensions, powders, foams, slurries or other coating compositions for seed, and also ULV formulations.

These formulations are prepared in a known manner, by mixing the active compound combinations according to the invention with customary additives such as, for example, customary extenders and also solvents or diluents, colorants, wetting agents, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, adhesives, gibberellins and also water.

Colorants which may be present in the seed-dressing formulations which can be used in accordance with the invention are all colorants which are customary for such purposes. It is possible to use either pigments, which are sparingly soluble in water, or dyes, which are soluble in water. Examples include the dyes known by the names Rhodamine B, C.I. Pigment Red 112 and C.I. Solvent Red 1.

Useful wetting agents which may be present in the seed dressing formulations usable in accordance with the invention are all substances which promote wetting, and which are conventionally used for the formulation of agrochemically active compounds. Preference is given to using alkylnaphthalenesulphonates, such as diisopropyl- or diisobutylnaphthalenesulphonates.

Useful dispersants and/or emulsifiers which may be present in the seed dressing formulations usable in accordance with the invention are all nonionic, anionic and cationic dispersants conventionally used for the formulation of active agrochemical ingredients. Preference is given to using nonionic or anionic dispersants or mixtures of nonionic or anionic dispersants. Suitable nonionic dispersants include in particular ethylene oxide/propylene oxide block polymers, alkylphenol poly glycol ethers and tristryrylphenol polyglycol ethers, and the phosphated or sulphated derivatives thereof. Suitable anionic dispersants are in particular lignosulphonates, polyacrylic acid salts and arylsulphonate/formaldehyde condensates.

Antifoams which may be present in the seed dressing formulations usable in accordance with the invention are all foam-inhibiting substances conventionally used for the formulation of active agrochemical ingredients. Preference is given to using silicone antifoams and magnesium stearate.

Preservatives which may be present in the seed dressing formulations usable in accordance with the invention are all substances usable for such purposes in agrochemical compositions. Examples include dichlorophene and benzyl alcohol hemiformal.

Secondary thickeners which may be present in the seed dressing formulations usable in accordance with the invention are all substances which can be used for such purposes in agrochemical compositions. Cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and finely divided silica are preferred. Adhesives which may be present in the seed dressing formulations usable in accordance with the invention are all customary binders usable in seed dressing products. Polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and tylose may be mentioned as being preferred.

Gibberellins which can be present in the seed-dressing formulations which can be used in accordance with the invention are preferably the gibberellins Al, A3 (= gibberellic acid), A4 and A7; gibberellic acid is especially preferably used. The gibberellins are known (cf. R. Wegler "Chemie der Pflanzenschutz- and Schadlingsbekampfungsmittel", vol. 2, Springer Verlag, 1970, pp. 401-412).

The seed dressing formulations usable in accordance with the invention can be used to treat a wide variety of different kinds of seed either directly or after prior dilution with water. For instance, the concentrates or the preparations obtainable therefrom by dilution with water can be used to dress the seed of cereals, such as wheat, barley, rye, oats, and triticale, and also the seed of maize, rice, oilseed rape, peas, beans, cotton, sunflowers, soya beans and beets, or else a wide variety of different vegetable seed. The seed dressing formulations usable in accordance with the invention, or the dilute use forms thereof, can also be used to dress seed of transgenic plants.

For treatment of seed with the seed dressing formulations usable in accordance with the invention, or the use forms prepared therefrom by adding water, all mixing units usable customarily for the seed dressing are useful. Specifically, the procedure in the seed dressing is to place the seed into a mixer, operated batch- wise or continously, to add the particular desired amount of seed dressing formulations, either as such or after prior dilution with water, and to mix everything until the formulation is distributed homogeneously on the seed. If appropriate, this is followed by a drying operation.

The application rate of the seed dressing formulations usable in accordance with the invention can be varied within a relatively wide range. It is guided by the particular content of the active compound combinations according to the invention in the formulations and by the seed. The application rates of the active compound combinations according to the invention are generally between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 15 g per kilogram of seed.

Vector control

The active compound combinations according to the invention can also be used in vector control. For the purpose of the present invention, a vector is an arthropod, in particular an insect or arachnid, capable of transmitting pathogens such as, for example, viruses, worms, single-cell organisms and bacteria from a reservoir (plant, animal, human, etc.) to a host. The pathogens can be transmitted either mechanically (for example trachoma by non-stinging flies) to a host, or by injection (for example malaria parasites by mosquitoes) into a host.

Examples of vectors and the diseases or pathogens they transmit are: 1) Mosquitoes

- Anopheles: malaria, filariasis;

- Culex: Japanese encephalitis, other viral diseases, filariasis, transmission of other worms;

- Aedes: yellow fever, dengue fever, other viral diseases, filariasis;

- Simuliidae: transmission of worms, in particular Onchocerca volvulus;

- Psychodidae: transmission of leishmaniasis

2) Lice: skin infections, epidemic typhus;

3) Fleas: plague, endemic typhus, cestodes;

4) Flies: sleeping sickness (trypanosomiasis); cholera, other bacterial diseases;

5) Mites: acariosis, epidemic typhus, rickettsialpox, tularaemia, Saint Louis encephalitis, tick-borne encephalitis (TBE), Crimean-Congo haemorrhagic fever, borreliosis;

6) Ticks: borellioses such as Borrelia burgdorferi sensu lato., Borrelia duttoni, tick-borne encephalitis, Q fever (Coxiella burnetii), babesioses (Babesia canis canis), ehrlichiosis.

Examples of vectors in the sense of the present invention are insects, for example aphids, flies, leafhoppers or thrips, which are capable of transmitting plant viruses to plants. Other vectors capable of transmitting plant viruses are spider mites, lice, beetles and nematodes.

Further examples of vectors in the sense of the present invention are insects and arachnids such as mosquitoes, in particular of the genera Aedes, Anopheles, for example A. gambiae, A. arabiensis, A. funestus, A. dirus (malaria) and Culex, psychodids such as Phlebotomus, Lutzomyia, lice, fleas, flies, mites and ticks capable of transmitting pathogens to animals and/or humans.

Vector control is also possible if the active compound combinations according to the invention are resistance breaking.

Active compound combinations according to the invention are suitable for use in the prevention of diseases and/or pathogens transmitted by vectors. Thus, a further aspect of the present invention is the use of active compound combinations according to the invention for vector control, for example in agriculture, in horticulture, in gardens and in leisure facilities, and also in the protection of materials and stored products. Protection of industrial materials

The active compound combinations according to the invention are suitable for protecting industrial materials against attack or destruction by insects, for example from the orders Coleoptera, Hymenoptera, Isoptera, Lepidoptera, Psocoptera and Zygentoma or by phytopathogenic fungi.

Industrial materials in the present context are understood to mean inanimate materials, such as preferably plastics, adhesives, sizes, papers and cards, leather, wood, processed wood products and coating compositions. The use of the invention for protecting wood is particularly preferred.

In a further embodiment, the active compound combinations according to the invention are used together with at least one further insecticide and/or one fungicide.

In a further embodiment, the active compound combinations according to the invention are present as a ready-to-use pesticide, i.e. they can be applied to the material in question without further modifications. Suitable further insecticides or fungicides are in particular those mentioned above.

Surprisingly, it has also been found that the active compound combinations according to the invention can be employed for protecting objects which come into contact with saltwater or brackish water, in particular hulls, screens, nets, buildings, moorings and signalling systems, against fouling. Likewise, the active compound combinations according to the invention, alone or in combinations with other active compounds, can be used as antifouling agents.

The plants listed can be treated particularly advantageously according to the invention with the active compound combinations according to the invention. The preferred ranges given above in the active compound combinations also apply to the treatment of these plants. Particular emphasis is placed on the plant treatment with the active compound combinations specifically mentioned in the present text.

Claims

Claims

1. Active compound combination comprising the compound of the formula (I)

and at least one active compound of group (II) which is selected from

Fungicide Groups (1) to (15) wherein Fungicide Groups (1) to (15) are:

(1) inhibitors of the ergosterol biosynthesis selected from the group consisting of (1.001) cyproconazole, (1.002) difenoconazole, (1.003) epoxiconazole, (1.004) fenbuconazole, (1.005) fenhexamid, (1.006) fenpropidin, (1.007) fenpropimorph, (1.008) fenpyrazamine, (1.009) Fluoxytioconazole, (1.010) fluquinconazole, (1.011) flutriafol, (1.012) hexaconazole, (1.013) imazalil, (1.014) imazalil sulfate, (1.015) ipconazole, (1.016) ipfentrifluconazole, (1.017) mefentrifluconazole, (1.018) metconazole, (1.019) myclobutanil, (1.020) paclobutrazol, (1.021) penconazole, (1.022) prochloraz, (1.023) propiconazole, (1.024) prothioconazole, (1.025) pyrisoxazole, (1.026) spiroxamine, (1.027) tebuconazole, (1.028) tetraconazole, (1.029) triadimenol, (1.030) tridemorph, (1.031) triticonazole, (1.032) 4-[[6-[(2R)-2-(2,4-difluorophenyl)- l,l-difluoro-2-hydroxy-3-(5-thioxo-4H-l,2,4-triazol-l-yl)propyl]-3-pyridyl]oxy]benzonitrile,

( 1.033) 4- [[6- [(2S)-2-(2,4-difluorophenyl)- 1 , 1 -difluoro-2-hydroxy-3-(5-thioxo-4H- 1 ,2,4-triazol- 1 - yl)propyl]-3-pyridyl]oxy]benzonitrile, (1.034) (2R)-2-[4-(4-chlorophenoxy)-2-

(trifluoromethyl)phenyl] - 1 -( 1H- 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.035) (2S)-2-[4-(4- chlorophenoxy)-2-(trifluoromethyl)phenyl] - 1 -( 1 H- 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.036) 1 - ({(2R,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-l,3-dioxolan-2-yl}methyl)-lH-

1 ,2,4-triazole, ( 1.037) 1 -( { (2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl] -4-methyl- 1,3- dioxolan-2-yl } methyl)- 1H- 1 ,2,4-triazole, ( 1.038) 2- [6-(4-bromophenoxy)-2-(trifluoromethyl)-3- pyridyl] - 1 -( 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.039) 2- [6-(4-chlorophenoxy)-2-(trifluoromethyl)-3- pyridyl] - 1 -( 1 ,2,4-triazol- 1 -yl)propan-2-ol, ( 1.040) 3- [2-( 1 -chlorocyclopropyl)-3-(3-chloro-2- fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile, (1.041) methyl 2-[2-chloro-4-(4- chlorophenoxy)phenyl]-2-hydroxy-3-(lH-l,2,4-triazol-l-yl)propanoate, (1.042) methyl (2R)-2-[2- chloro-4-(4-chlorophenoxy)phenyl] -2-hydroxy-3-( 1 ,2,4-triazol- 1 -yl)propanoate, ( 1.043) methyl (S)-2- [2-chloro-4-(4-chlorophenoxy)phenyl] -2-hydroxy-3-( 1 ,2,4-triazol- 1 -yl)propanoate, ( 1.044) N'-(2,5-dimethyl-4-(2-methylbenzyl)phenyl)-N-ethyl-N-methylformimidamide, (1.045) N'-(2- chloro-4-(4-cyanobenzyl)-5-methylphenyl)-N-ethyl-N-methylformimidamide, (1.046) N'-(2- chloro-4-(4-methoxybenzyl)-5-methylphenyl)-N-ethyl-N-methylformimidamide, (1.047) N'-(2- chloro-5-methyl-4-phenoxyphenyl)-N-ethyl-N-methylimidofonnamide, (1.048) N'-(4-benzyl-2- chloro-5-methylphenyl)-N-ethyl-N-methylformimidamide, ( 1.049) N'- [2-chloro-4-(2- fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylimidoformamide, (1.050) N'-[5-bromo-6-(2,3- dihydro-lH-inden-2-yloxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylimidoformamide, (1.051) N'- {4-[(4,5-dichloro-l,3-thiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylimidoformamide, (1.052) N'-{5-bromo-2-methyl-6-[(l-propoxypropan-2-yl)oxy]pyridin-3-yl}-N-ethyl-N- methylimidoformamide, ( 1.053) N'- { 5-bromo-6- [( 1R)- 1 -(3,5-difluorophenyl)ethoxy] -2- methylpyridin-3-yl } -N-ethyl-N-methylimidoformamide, ( 1.054) N'- { 5-bromo-6-[( 1 S)- 1 -(3 ,5- difluorophenyl)ethoxy] -2-methylpyridin-3 -yl } -N -ethyl-N -methylimidoformamide, (1.055) N'-{5- bromo-6-[(cis-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N- methylimidoformamide, (1.056) N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2- methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.057) N'-{5-bromo-6-[l-(3,5- difluorophenyl)ethoxy] -2-methylpyridin-3 -yl } -N -ethyl-N -methylimidoformamide, ( 1.058) N- isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-l-hydroxy-l-phenylethyl)phenyl]-N- methylimidoformamide, (1.059) p-tolylmethyl 4-[(E)-[ethyl(methyl)amino]methyleneamino]-2,5- dimethyl-benzoate and (1.060) N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl- formamidine;

(2) inhibitors of the respiratory chain at complex I or II selected from the group consisting of (2.001) benzovindiflupyr, (2.002) bixafen, (2.003) boscalid, (2.004) carboxin, (2.005) cyclobutrifluram, (2.006) flubeneteram, (2.007) fluindapyr, (2.008) fluopyram, (2.009) flutolanil, (2.010) fluxapyroxad, (2.011) furametpyr, (2.012) inpyrfluxam, (2.013) Isofetamid, (2.014) isoflucypram, (2.015) isopyrazam, (2.016) penflufen, (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.019) pyrapropoyne, (2.020) pyraziflumid, (2.021) sedaxane, (2.022) Thifluzamide (aka trifluzamide), (2.023) 5,8-difluoro-N-[2-(2-fluoro-4-{[4-(trifluoromethyl)pyridin-2- yl]oxy}phenyl)ethyl]quinazolin-4-amine, (2.024) 5-chloro-N-[2-[l-(4-chlorophenyl)pyrazol-3- yl]oxy ethyl] -6-ethyl-pyrimidin-4-amine, (2.025) N- [2- [ 1 -(4-chlorophenyl)pyrazol-3- yl]oxyethyl]quinazolin-4-amine, (2.026) l-methyl-3-(trifluoromethyl)-N-[2'-

(trifluoromethyl)bipheny 1-2-yl] - 1 H-pyrazole-4-carboxamide, (2.027) 2-fluoro-6-(trifluoromethyl)- N-( 1 , 1 ,3-trimethyl-2,3-dihydro- 1 H-inden-4-yl)benzamide, (2.028) 3-(difhroromethyl)- 1 -methyl-N- (l,l,3-trimethyl-2,3-dihydro-lH-inden-4-yl)-lH-pyrazole-4-carboxamide, (2.029) 3-

(difluoromethyl)- 1 -methyl-N- [(3 S) - 1 , 1 ,3-trimethyl-2,3-dihydro- 1 H-inden-4-yl] - 1 H-pyrazole-4- carboxamide, (2.030) 3-(difluoromethyl)-N-[(3R)-7-fluoro-l,l,3-trimethyl-2,3-dihydro-lH-inden- 4-yl]-l-methyl-lH-pyrazole-4-carboxamide, (2.031) 3-(difluoromethyl)-N-[(3S)-7-fluoro-l,l,3- trimethyl-2,3-dihydro-lH-inden-4-yl]-l-methyl-lH-pyrazole-4-carboxamide, (2.032) N-[(1R,4S)- 9-(dichloromethylene)- 1 ,2,3,4-tetrahydro- 1 ,4-methanonaphthalen-5-yl] -3-(difluoromethyl)- 1 - methyl- 1 H-pyrazole-4-carboxamide, (2.033) N-[( 1 S,4R)-9-(dichloromethylene)- 1 ,2,3,4- tetrahydro- 1 ,4-methanonaphthalen-5-yl] -3-(difluoromethyl)- 1 -methyl- 1 H-pyrazole-4- carboxamide, (2.034) N- [ 1 -(2,4-dichlorophenyl)- 1 -methoxypropan-2-yl] -3-(difluoromethyl)- 1 - methyl- 1 H-pyrazole-4-carboxamide, (2.035) 5-chloro- 1 ,3-dimethyl-N- [(3 S) - 1 , 1 ,3-trimethyl-3H- isobenzofuran-4-yl]pyrazole-4-carboxamide, (2.036) 5-chloro-l,3-dimethyl-N-[(3R)-l,l,3- trimethyl-3H-isobenzofuran-4-yl]pyrazole-4-carboxamide, (2.037) N-[2-[(lS)-l,3- dimethylbutyl]phenyl]-5-fluoro-l ,3-dimethyl-pyrazole-4-carboxamide, (2.038) N-[2-[(lR)-l ,3- dimethylbutyl]phenyl]-5-fluoro-l ,3-dimethyl-pyrazole-4-carboxamide, (2.039) 3-(difluoromethyl)- N-methoxy-l-methyl-N-[(lS)-l-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide, (2.040) 3-(difluoromethyl)-N-methoxy-l-methyl-N-[(lR)-l-methyl-2-(2,4,6- trichlorophenyl)ethyl]pyrazole-4-carboxamide, (2.041) N- [2-[( 1 S)- 1 ,3-dimethylbutyl] -3-thienyl] - 1 -methyl-3-(trifluoromethyl)pyrazole-4-carboxamide, (2.042) N- [2- [( 1R)- 1 ,3-dimethylbutyl] -3- thienyl]-l-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide, (2.043) N-[rac-(lS,2S)-2-(2,4- dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide and (2.044) 2-(difhroromethyl)-N-(3- ethyl- 1 , 1 -dimethyl-indan-4-yl)pyridine-3-carboxamide;

(3) inhibitors of the respiratory chain at complex III selected from the group consisting of (3.001) ametoctradin, (3.002) amisulbrom, (3.003) azoxystrobin, (3.004) coumethoxystrobin, (3.005) coumoxystrobin, (3.006) cyazofamid, (3.007) dimoxystrobin, (3.008) enoxastrobin, (3.009) famoxadone, (3.010) fenamidone, (3.011) fenpicoxamid, (3.012) florylpicoxamid, (3.013) flufenoxystrobin, (3.014) fluoxastrobin, (3.015) kresoxim-methyl, (3.016) mandestrobin, (3.017) metarylpicoxamid, (3.018) metominostrobin, (3.019) metyltetraprole, (3.020) orysastrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3.023) pyrametostrobin, (3.024) pyraoxystrobin, (3.025) pyribencarb, (3.026) trifloxystrobin, (3.027) (2E)-2-{2-[({[(lE)-l-(3-{[(E)-l-fluoro-2- phenyl vinyl] oxy } phenyl)ethylidene] amino } oxy)methyl]phenyl } -2-(methoxyimino)-N - methylacetamide, (3.028) (2E,3Z)-5-{ [l-(4-chloro-2-fluorophenyl)-lH-pyrazol-3-yl]oxy}-2-

(methoxyimino)-N,3-dimethylpent-3-enamide, (3.029) (2E,3Z)-5-{ [l-(4-chlorophenyl)-lH- pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.030) (2R)-2-{2-[(2,5- dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.031) (2S)-2-{2-[(2,5- dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.032) (Z,2E)-5-[l-(2,4- dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide, (3.033) methyl (Z)-2-(5-cyclohexyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate, (3.034) methyl (Z)-2-(5- cyclopentyl-2-methyl-phenoxy)-3-methoxy-prop-2-enoate, (3.035) methyl (Z)-3 -methoxy-2- [2- methyl-5-(3-propylpyrazol-l-yl)phenoxy]prop-2-enoate, (3.036) methyl (Z)-3-methoxy-2-[2- methyl-5-[3-(trifluoromethyl)pyrazol-l-yl]phenoxy]prop-2-enoate, (3.037) methyl {5-[3-(2,4- dimethylphenyl)-lH-pyrazol-l-yl]-2-methylbenzyl}carbamate, (3.038) (2E)-2-methoxyimino-N- methyl-2- [3 -methyl-2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylidene- amino]oxymethyl]phenyl] acetamide, (3.039) (2E)-2- [2- [[(E)- 1 -(3 ,5-difluorophenyl)ethylidene- amino]oxymethyl]-3-methyl-phenyl]-2-methoxyimino-N-methyl-acetamide, (3.040) [rac-2-(4- bromo-7-fluoro-indol- 1 -yl)- 1 -methyl-propyl] (2S)-2- [(3-hydroxy-4-methoxy-pyridine-2- carbonyl)amino]propanoate, (3.041) [rac-2-(7-bromo-4-fluoro-indol-l-yl)-l -methyl-propyl] (2S)- 2-[(3-acetoxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.042) [rac-2-(7-bromoindol-l- yl)- 1 -methyl-propyl] (2S)-2- [(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.043) [rac-2-(3,5-dichloro-2-pyridyl)-l-methyl-propyl] (2S)-2-[(3-hydroxy-4-methoxy-pyridine- 2-carbonyl)amino]propanoate, (3.044) [(lS)-l-[l-(l-naphthyl)cyclopropyl]ethyl] (2S)-2-[(3- acetoxy-4-methoxy-pyridine-2-carbonyl)amino]propanoate, (3.045) [( 1 S)- 1 -[ 1 -( 1 - naphthyl)cyclopropyl] ethyl] (2S)-2-[(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino]- propanoate, (3.046) [(lS)-l-[l-(l-naphthyl)cyclopropyl]ethyl] (2S)-2-[[3-(acetoxymethoxy)-4- methoxy-pyridine-2-carbonyl]amino]propanoate, (3.047) [2-[[(lS)-2-[(lRS,2SR)-2-(3,5-dichloro- 2-pyridyl)-l-methyl-propoxy]-l-methyl-2-oxo-ethyl]carbamoyl]-4-methoxy-3-pyridyl]oxymethyl 2-methylpropanoate, (3.048) 2-[cyano-(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)- 5-methyl-thiazole-4-carboxamide, (3.049) 2- [cyano-(2,6-difluoro-4-pyridyl)amino] -5-methyl-N- spiro[3.4]octan-3-yl-thiazole-4-carboxamide, (3.050) 2-[cyano-(2,6-difluoro-4-pyridyl)amino]-N- hexyl-5-methyl-thiazole-4-carboxamide, (3.051) 2-[acetyl-(2,6-difluoro-4-pyridyl)amino]-N-(2,2- dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide, (3.052) 2-[(2,6-difluoro-4-pyridyl)-(2- methylpropanoyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide, (3.053) 2- [(2,6-difluoro-4-pyridyl)-(2-methoxyacetyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-

4-carboxamide and (3.054) N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formamido-2- hydroxybenzamide ;

(4) inhibitors of the mitosis and cell division selected from the group consisting of (4.001) carbendazim, (4.002) diethofencarb, (4.003) ethaboxam, (4.004) fluopicolide, (4.005) fluopimomide, (4.006) metrafenone, (4.007) pencycuron, (4.008) pyridachlometyl, (4.009) pyriofenone (chlazafenone), (4.010) thiabendazole, (4.011) thiophanate-methyl, (4.012) zoxamide, (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)-6-methylpyridazine, (4.014) 3-chloro-

5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluorophenyl)pyridazine, (4.015) 4-(2-bromo-4- fluorophenyl)-N-(2,6-difluorophenyl)- 1 ,3-dimethyl- 1 H-pyrazol-5-amine, (4.016) 4-(2-bromo-4- fluorophenyl)-N-(2-bromo-6-fluorophenyl)- 1 ,3-dimethyl- lH-pyrazol-5-amine, (4.017) 4-(2- bromo-4-fluorophenyl)-N-(2-bromophenyl)- 1 ,3-dimethyl- lH-pyrazol-5-amine, (4.018) 4-(2- bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.019) 4- (2-bromo-4-fluorophenyl)-N-(2-chlorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.020) 4-(2- bromo-4-fluorophenyl)-N-(2-fluorophenyl)- 1 ,3-dimethyl- lH-pyrazol-5-amine, (4.021) 4-(2- chloro-4-fluorophenyl)-N-(2,6-difluorophenyl)-l ,3-dimethyl-lH-pyrazol-5-amine, (4.022) 4-(2- chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.023) 4- (2-chloro-4-fluorophenyl)-N-(2-chlorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine, (4.024) 4-(2- chloro-4-fluorophenyl)-N-(2-fluorophenyl)- 1 ,3-dimethyl- lH-pyrazol-5-amine, (4.025) 4-(4- chlorophenyl)-5-(2,6-difluorophenyl)-3,6-dimethylpyridazine, (4.026) N-(2-bromo-6- fluorophenyl)-4-(2-chloro-4-fluorophenyl)- 1 ,3-dimethyl- lH-pyrazol-5-amine, (4.027) N-(2- bromophenyl)-4-(2-chloro-4-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine and (4.028) N-(4- chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)-l,3-dimethyl-lH-pyrazol-5-amine;

(5) compounds capable to have a multisite action selected from the group consisting of (5.001) bordeaux mixture, (5.002) captafol, (5.003) captan, (5.004) chlorothalonil, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(2+) sulfate, (5.010) dithianon, (5.011) dodine, (5.012) folpet, (5.013) mancozeb, (5.014) maneb, (5.015) metiram, (5.016) metiram zinc, (5.017) oxine-copper, (5.018) propineb, (5.019) sulfur and sulfur preparations including calcium polysulfide, (5.020) thiram, (5.021) zineb, (5.022) ziram and (5.023) 6-ethyl-5,7-dioxo-6,7-dihydro-5H-pyrrolo[3',4':5,6][l,4]dithiino[2,3- c] [1 ,2]thiazole-3-carbonitrile;

(6) compounds capable to induce a host defence selected from the group consisting of (6.001) acibenzolar-S-methyl, (6.002) fosetyl-aluminium, (6.003) fosetyl-calcium, (6.004) fosetyl-sodium, (6.005) isotianil, (6.006) phosphorous acid and its salts, (6.007) probenazole and (6.008) tiadinil;

(7) inhibitors of the amino acid and/or protein biosynthesis selected from the group consisting of (7.001) cyprodinil, (7.002) kasugamycin, (7.003) kasugamycin hydrochloride hydrate, (7.004) oxytetracycline and (7.005) pyrimethanil;

(8) inhibitors of the ATP production: (8.001) silthiofam;

(9) inhibitors of the cell wall synthesis selected from the group consisting of (9.001) benthiavalicarb, (9.002) dimethomorph, (9.003) flumorph, (9.004) iprovalicarb, (9.005) mandipropamid, (9.006) pyrimorph, (9.007) valifenalate, (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-l- (morpholin-4-yl)prop-2-en- 1 -one and (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)- 1 -(morpholin-4-yl)prop-2-en- 1 -one ;

(10) inhibitors of the lipid synthesis or transport, or membrane synthesis selected from the group consisting of (10.001) fluoxapiprolin, (10.002) natamycin, (10.003) oxathiapiprolin, (10.004) propamocarb, (10.005) propamocarb hydrochloride, (10.006) propamocarb-fosetylate, (10.007) tolclofos-methyl, (10.008) l-(4-{4-[(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-l,2-oxazol-3-yl]-l,3- thiazol-2-yl } piperidin- 1 -yl)-2- [5 -methyl-3 -(trifluoromethyl)- 1 H-pyrazol- 1 -yl] ethanone, ( 10.009) l-(4-{4-[(5S)-5-(2,6-difluorophenyl)-4,5-dihydro-l,2-oxazol-3-yl]-l,3-thiazol-2-yl}piperidin-l- yl)-2-[5-methyl-3-(trifluoromethyl)-lH-pyrazol-l-yl]ethanone, (10.010) 2-[3,5- bis(difluoromethyl)- 1 H-pyrazol- 1 -yl] - 1 - [4- (4- { 5- [2-(prop-2-yn- 1 -yloxy)phenyl] -4,5-dihydro- 1 ,2- oxazol-3-yl}-l,3-thiazol-2-yl)piperidin-l-yl]ethanone, (10.011) 2-[3,5-bis(difluoromethyl)-lH- pyrazol- 1 -yl] - 1 - [4- (4- { 5 - [2-chloro-6-(prop-2-yn- 1 -yloxy)phenyl] -4,5 -dihydro- 1 ,2-oxazol-3 -yl } - 1.3-thiazol-2-yl)piperidin-l-yl]ethanone, (10.012) 2-[3,5-bis(difluoromethyl)-lH-pyrazol-l-yl]-l-

[4-(4-{5-[2-fluoro-6-(prop-2-yn-l-yloxy)phenyl]-4,5-dihydro-l,2-oxazol-3-yl}-l,3-thiazol-2- yl)piperidin-l-yl]ethanone, (10.013) 2-{(5R)-3-[2-(l-{ [3,5-bis(difluoromethyl)-lH-pyrazol-l- yl] acetyl } piperidin-4-yl)- 1 ,3 -thiazol-4-yl] -4,5 -dihydro- 1 ,2-oxazol-5 -yl } -3 -chlorophenyl methanesulfonate, (10.014) 2- { (5S)-3-[2-( 1 - { [3 ,5-bis(difluoromethyl)- 1 H-pyrazol- 1 - yl] acetyl } piperidin-4-yl)- 1 ,3 -thiazol-4-yl] -4,5 -dihydro- 1 ,2-oxazol-5 -yl } -3 -chlorophenyl methanesulfonate, (10.015) 2- { 3-[2-(l- { [3 ,5-bis(difluoromethyl)-l H-pyrazol- 1- yl] acetyl } piperidin-4-yl)- 1 ,3 -thiazol-4-yl] -4,5 -dihydro- 1 ,2-oxazol-5 -yl } phenyl methanesulfonate, (10.016) 3-[2-(l-{ [5-methyl-3-(trifluoromethyl)-lH-pyrazol-l-yl]acetyl}piperidin-4-yl)-l,3- thiazol-4-yl]-l,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.017) 9-fluoro-3-[2-(l-{ [5- methyl-3-(trifluoromethyl)- IH-pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol-4-yl] - 1 ,5-dihydro-

2.4-benzodioxepin-6-yl methanesulfonate, (10.018) 3-[2-(l-{ [3,5-bis(difluoromethyl)-lH-pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol-4-yl] - 1 ,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate and ( 10.019) 3- [2-( 1 - { [3 ,5-bis(difhroromethyl)- 1 H-pyrazol- 1 -yl] acetyl }piperidin-4-yl)- 1 ,3-thiazol- 4-yl] -9-fluoro- 1 ,5 -dihydro-2, 4-benzodioxepin-6-yl methanesulfonate ;

(11) inhibitors of the melanin biosynthesis selected from the group consisting of (11.001) tolprocarb and (11.002) tricyclazole;

(12) inhibitors of the nucleic acid synthesis selected from the group consisting of (12.001) benalaxyl, (12.002) benalaxyl-M (kiralaxyl), (12.003) metalaxyl and (12.004) metalaxyl-M (mefenoxam);

(13) inhibitors of the signal transduction selected from the group consisting of (13.001) fludioxonil, (13.002) iprodione, (13.003) procymidone, (13.004) proquinazid, (13.005) quinoxyfen and (13.006) vinclozolin;

(14) compounds capable to act as an uncoupler selected from the group consisting of (14.001) fluazinam and (14.002) meptyldinocap; and

(15) further compounds selected from the group consisting of (15.001) abscisic acid, (15.002) aminopyrifen, (15.003) benthiazole, (15.004) bethoxazin, (15.005) capsimycin, (15.006) carvone, (15.007) chinomethionat, (15.008) chloroinconazide, (15.009) cufraneb, (15.010) cyflufenamid, (15.011) cymoxanil, (15.012) cyprosulfamide, (15.013) dipymetitrone, (15.014) D-tagatose, (15.015) flufenoxadiazam, (15.016) flumetylsulforim, (15.017) flutianil, (15.018) ipflufenoquin, (15.019) methyl isothiocyanate, (15.020) mildiomycin, (15.021) nickel dimethyldithiocarbamate, (15.022) nitrothal-isopropyl, (15.023) oxyfenthiin, (15.024) pentachlorophenol and salts, (15.025) picarbutrazox, (15.026) quinofumelin, (15.027) tebufloquin, (15.028) tecloftalam, (15.029) tolnifanide, (15.030) 2-(6-benzylpyridin-2-yl)quinazoline, (15.031) 2-[6-(3-fluoro-4- methoxyphenyl)-5-methylpyridin-2-yl]quinazoline, (15.032) 2-phenylphenol and salts, (15.033) 4- amino-5-fluoropyrimidin-2-ol (tautomeric form: 4-amino-5-fluoropyrimidin-2(lH)-one), (15.034) 4-oxo-4-[(2-phenylethyl)amino]butanoic acid, (15.035) 5-amino-l,3,4-thiadiazole-2-thiol, (15.036)

5-chloro-N'-phenyl-N'-(prop-2-yn-l-yl)thiophene-2-sulfonohydrazide, (15.037) 5-fluoro-2-[(4- fluorobenzyl)oxy]pyrimidin-4-amine, (15.038) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidin-4- amine, (15.039) but-3-yn-l-yl {6-[({[(Z)-(l-methyl-lH-tetrazol-5- yl)(phenyl)methylene] amino }oxy)methyl]pyridin-2-yl} carbamate, (15.040) ethyl (2Z)-3-amino-2- cyano-3-phenylacrylate, (15.041) methyl 2- [acetyl- [2-ethy lsulfonyl-4-

(trifluoromethyl)benzoyl]amino]-5-(trifluoromethoxy)benzoate, (15.042) N-acetyl-N-[2-bromo-4- (trifluoromethoxy)phenyl] -2-ethy lsulfonyl-4-(trifluoromethyl)benzamide, ( 15.043) phenazine- 1 - carboxylic acid, (15.044) propyl 3,4,5-trihydroxybenzoate, (15.045) quinolin-8-ol, (15.046) quinolin-8-ol sulfate (2:1), (15.047) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl- pentanamide, (15.048) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl- pentanamide, (15.049) l-(4,5-dimethyl-lH-benzimidazol-l-yl)-4,4-difluoro-3,3-dimethyl-3,4- dihydroisoquinoline, (15.050) l-(4,5-dimethylbenzimidazol-l-yl)-4,4,5-trifluoro-3,3-dimethyl- isoquinoline, ( 15.051 ) 1 -(5-(fluoromethyl)-6-methyl-pyridin-3-yl)-4,4-difluoro-3 ,3-dimethyl-3 ,4- dihydroisoquinoline, ( 15.052) 1 -(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3 ,3-dimethyl-3 ,4- dihydroisoquinoline, (15.053) l-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl)-4,4-difluoro-3,3- dimethyl-3,4-dihydroisoquinoline, (15.054) l-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4- difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.055) 4,4-difluoro-3,3-dimethyl-l-(7- methylpyrazolo[l,5-a]pyridin-3-yl)isoquinoline, (15.056) l-(6,7-dimethylpyrazolo[l,5-a]pyridin- 3-yl)-4,4,5-trifluoro-3,3-dimethyl-isoquinoline, (15.057) l-(6,7-dimethylpyrazolo[l,5-a]pyridin-3- yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.058) 2-{2-fluoro-6-[(8-fluoro-2- methylquinolin-3-yl)oxy]phenyl}propan-2-ol, (15.059) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4- dihydroisoquinolin-l-yl)quinoline, (15.060) 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin- l-yl)-8-fluoroquinoline, (15.061) 3-(4,4-difluoro-5,5-dimethyl-4,5-dihydrothieno[2,3-c]pyridin-7- yl)quinoline, ( 15.062) 3-(5-fluoro-3 ,3,4,4-tetramethyl-3 ,4-dihydroisoquinolin- 1 -yl)quinoline, (15.063) 4,4-difluoro-3,3-dimethyl-l-(4-methylbenzimidazol-l-yl)isoquinoline, (15.064) 4,4- difluoro-3,3-dimethyl-l-(6-methylpyrazolo[l,5-a]pyridin-3-yl)isoquinoline, (15.065) 5-bromo-l- (5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.066) 7,8-difluoro-N-[rac-l- benzyl-l,3-dimethyl-butyl]quinoline-3-carboxamide, (15.067) 8-fluoro-3-(5-fluoro-3,3,4,4- tetramethyl-3 ,4-dihydroisoquinolin- l-yl)-quinoline, (15.068) 8-fluoro-3-(5-fluoro-3,3-dimethyl-

3.4-dihydroisoquinolin-l-yl)-quinoline, (15.069) 8-fluoro-N-(4,4,4-trifluoro-2-methyl-l- phenylbutan-2-yl)quinoline-3 -carboxamide, ( 15.070) 8 -fluoro-N - [ ( 1 R) - 1 - [ (3 - fluorophenyl)methyl] - 1 ,3 -dimethyl-butyl] quinoline-3 -carboxamide, ( 15.071 ) 8 -fluoro-N -[(1S)-1- [(3-fluorophenyl)methyl]-l,3-dimethyl-butyl]quinoline-3-carboxamide, (15.072) 8-fluoro-N-[(2S)-

4.4.4-trifluoro-2-methyl-l-phenylbutan-2-yl]quinoline-3-carboxamide, (15.073) 8 -fluoro-N- [rac-1- [(3-fluorophenyl)methyl]-l,3-dimethyl-butyl]quinoline-3-carboxamide, (15.074) 9-fluoro-2,2- dimethyl-5-(quinolin-3-yl)-2,3-dihydro-l,4-benzoxazepine, (15.075) N-(2,4-dimethyl-l- phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.076) N-[(lR)-l-benzyl-l,3-dimethyl- butyl]-7,8-difluoro-quinoline-3-carboxamide, (15.077) N-[(lS)-l-benzyl-l,3-dimethyl-butyl]-7,8- difluoro-quinoline-3-carboxamide, (15.078) N-[(2R)-2,4-dimethyl-l-phenylpentan-2-yl]-8- fluoroquinoline-3-carboxamide, (15.079) rac-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4- dimethyl-pentanamide, (15.080) (5RS)-3-[3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin- 4-yl]-5-(2,4-dimethylbenzyl)-5,6-dihydro-4H-l,2,4-oxadiazine, (15.081) (5S)-3-[3-(3-cyclopropyl- 2-fluorophenoxy)-6-methylpyridazin-4-yl] -5-(2,4-dimethylbenzyl)-5 ,6-dihydro-4H- 1 ,2,4- oxadiazine, (15.082) (5RS)-5-(4-bromo-2-methylbenzyl)-3-[3-(3-chloro-2-fluorophenoxy)-6- methylpyridazin-4-yl]-5,6-dihydro-4H-l,2,4-oxadiazine, (15.083) (5RS)-3-[3-(3-chloro-2- fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-l,2,4- oxadiazine, (15.084) (5S)-5-(4-bromo-2-methylbenzyl)-3-[3-(3-chloro-2-fluorophenoxy)-6- methylpyridazin-4-yl]-5,6-dihydro-4H-l,2,4-oxadiazine, (15.085) (5R)-3-[3-(3-chloro-2- fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-l,2,4- oxadiazine, (15.086) (5 S) -3 - [3 -(3 -chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl] -5 -(2-chloro-4- methylbenzyl)-5,6-dihydro-4H-l ,2,4-oxadiazine, (15.087) 6-chloro-3-(3-cyclopropyl-2- fluorophenoxy)-N-[2-(2,4-dimethylphenyl)-2,2-difluoroethyl]-5-methylpyridazine-4-carboxamide, (15.088) 3-(3-bromo-2-fluoro-phenoxy)-6-chloro-N-[2-(2-chloro-4-methylphenyl)-2,2- difluoroethyl]-5-methylpyridazine-4-carbox-amide, (15.089) 6-chloro-N-[2-(2-chloro-4- methylphenyl)-2,2-difluoroethyl]-3-(3-cyclopropyl-2-fluoro-phenoxy)-5-methylpyridazine-4- carboxamide, (15.090) 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[2-(3,4-dimethylphenyl)- 2,2-difluoroethyl] -5-methylpyridazine-4-carboxamide, ( 15.091 ) 6-chloro-3 -(3 -chloro-2- fluorophenoxy)-N-[2-(2,4-dimethylphenyl)-2,2-difluoroethyl]-5-methylpyridazine-4- carbox-amide, (15.092) N-[2-(2-bromo-4-methylphenyl)-2,2-difluoroethyl]-6-chloro-3-(3- cyclopropyl-2-fluoro-phenoxy)-5-methylpyridazine-4-carboxamide, ( 15.093) 1,1 -diethyl-3- [[4- [5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.094) l,3-dimethoxy-l-[[4-[5-

(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.095) l-[[3-fluoro-4-(5-(trifluoro- methyl)- 1 ,2,4-oxadiazol-3-yl)phenyl]methyl] azepan-2-one, ( 15.096) 1 - [[4- [5-(trifluoromethyl)-

1.2.4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, ( 15.097) 1 -methoxy- 1 -methyl-3- [[4- [5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.098) l-methoxy-3-methyl-l-[[4-[5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.099) 2-(difluoromethyl)-5-[2-[l- (2,6-difluorophenyl)cyclopropoxy]pyrimidin-5-yl]-l,3,4-oxadiazole, (15.100) 2,2-difluoro-N- methyl-2-[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]acetamide, (15.101) 3,3-dimethyl-l- [[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.102) 3-ethyl-l- methoxy-l-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.103) 4,4- dimethyl-l-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.104)

4.4-dimethyl-2-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one,

(15.105) 4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl dimethylcarbamate, (15.106) 5,5- dimethyl-2-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.107) 5-[5-(difluoromethyl)-l,3,4-oxadiazol-2-yl]-N-[(lR)-l-(2,6-difluorophenyl)- ethyl]pyrimidin-2-amine, (15.108) 5-[5-(difluoromethyl)-l,3,4-oxadiazol-2-yl]-N-[(lR)-l-(2,6- difluorophenyl)propyl]pyrimidin-2-amine, (15.109) 5- [5-(difluoromethyl)- 1 ,3 ,4-oxadiazol-2-yl] - N- [( 1R)- 1 -(2-fluorophenyl)ethyl]pyrimidin-2-amine, (15.110) 5- [5-(difluoromethyl)- 1 ,3,4- oxadiazol-2-yl] -N-[( 1 R)- 1 -(2-fluorophenyl)ethyl]pyrimidin-2-amine, (15.111) 5- [5-

(difluoromethyl)-l,3,4-oxadiazol-2-yl]-N-[(lR)-l-(3,5-difluorophenyl)ethyl]pyrimidin-2-amine,

(15.112) 5- [5-(difluoromethyl)- 1 ,3 ,4-oxadiazol-2-yl] -N-[( 1 R)- 1 -phenylethyl]pyrimidin-2-amine,

(15.113) 5-[5-(difluoromethyl)-l,3,4-oxadiazol-2-yl]-N-[l-(2- fluorophenyl)cyclopropyl]pyrimidin-2-amine, (15.114) 5-methyl- 1 - [[4- [5-(trifluoromethyl)- 1 ,2,4- oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.115) ethyl l-{4-[5-(trifluoromethyl)-l,2,4- oxadiazol-3-yl]benzyl}-lH-pyrazole-4-carboxylate, (15.116) methyl {4-[5-(trifluoromethyl)-l,2,4- oxadiazol-3-yl]phenyl} carbamate, (15.117) N-(l-methylcyclopropyl)-4-[5-(trifluoromethyl)-l,2,4- oxadiazol-3-yl]benzamide, (15.118) N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-l ,2,4- oxadiazol-3-yl]benzamide, (15.119) N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl]methyl]propanamide, ( 15.120) N,N-dimethyl- 1 - { 4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol- 3-yl]benzyl}-lH-l,2,4-triazol-3-amine, (15.121) N-[(E)-methoxyiminomethyl]-4-[5- (trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzamide, (15.122) N-[(E)-N-methoxy-C -methylcarbonimidoyl] -4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3-yl]benzamide, ( 15.123) N-[(Z)- methoxyiminomethyl]-4-[5-(trifluoromethyl)-l ,2,4-oxadiazol-3-yl]benzamide, (15.124) N-[(Z)-N- methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzamide,

(15.125) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-l ,2,4-oxadiazol-3-yl]phenyl]methyl]-3,3,3- trifluoro-propanamide, (15.126) N- [[4- [5-(trifluoromethyl)- 1 ,2,4-oxadiazol-3- yl]phenyl]methyl]propanamide, (15.127) N- [4- [5 -(trifluoromethyl)- 1 ,2,4-oxadiazol-3- yl]phenyl]cyclopropanecarboxamide, (15.128) N- { 2,3-difluoro-4- [5-(trifluoromethyl)- 1 ,2,4- oxadiazol-3-yl]benzyl } butanamide, (15.129) N-{4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]benzyl } cyclopropanecarboxamide, (15.130) N-{4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl}propanamide, (15.131) N-allyl-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]- methyl] acetamide, (15.132) N-allyl-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]phenyl]- methyl]propanamide, (15.133) N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl]methyl]propanamide, (15.134) N -methoxy-N - [ [4- [5 -(trifluoromethyl)- 1 ,2,4-oxadiazol-

3-yl]phenyl]methyl]cyclopropanecarboxamide, (15.135) N-methy 1-4- [5-(trifluoromethyl)- 1,2,4- oxadiazol-3-yl]benzamide, (15.136) N-methyl-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]benzenecarbothioamide, (15.137) N-methyl-N-phenyl-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]benzamide and (15.138) 2,2-difluoro-2-[4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3- yl]phenyl]acetic acid.

2. Use of an active compound combination as claimed in claim 1 for controlling animal pests.

3. Use of an active compound combination as claimed in claim 1 for controlling microbial pests.

4. Use of an active compound combination as claimed in claim 1 for controlling nematodes.

5. Use of an active compound combination as claimed in claim 1 for controlling unwanted microorganism.

6. Use of an active compound combination as claimed in claim 1 on transgenic plants. 7. Method of controlling animal or microbial pests, characterized in that active compound combinations as claimed in claim 1 are allowed to act on animal or microbial pests and/or their habitat.

8. Method of controlling unwanted microorganism, characterized in that active compound combinations as claimed in claim 1 are allowed to act on unwanted microorganism and/or their habitat.

9. Process for preparing a crop protection agent, characterized in that active compound combinations as claimed in claim 1 are mixed with extenders and/or surfactants.

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Citations (133)

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  • 2024-10-31 WO PCT/EP2024/080838 patent/WO2025098874A1/en active Pending

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