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WO2019057250A1 - Appareil d'ionophorèse portatif pour le traitement du cuir chevelu - Google Patents

Appareil d'ionophorèse portatif pour le traitement du cuir chevelu Download PDF

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Publication number
WO2019057250A1
WO2019057250A1 PCT/DE2018/100806 DE2018100806W WO2019057250A1 WO 2019057250 A1 WO2019057250 A1 WO 2019057250A1 DE 2018100806 W DE2018100806 W DE 2018100806W WO 2019057250 A1 WO2019057250 A1 WO 2019057250A1
Authority
WO
WIPO (PCT)
Prior art keywords
iontophoresis
conductive polymer
scalp
bristles
polymer bristles
Prior art date
Application number
PCT/DE2018/100806
Other languages
German (de)
English (en)
Other versions
WO2019057250A8 (fr
Original Assignee
Wellstar Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstar Gmbh & Co. Kg filed Critical Wellstar Gmbh & Co. Kg
Priority to DE112018005438.1T priority Critical patent/DE112018005438A5/de
Publication of WO2019057250A1 publication Critical patent/WO2019057250A1/fr
Publication of WO2019057250A8 publication Critical patent/WO2019057250A8/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Definitions

  • the invention relates to a handheld lontophoresis device for scalp treatment, in particular for the regeneration of hair follicles in the scalp, according to the preamble of claim 1.
  • Such a handset includes a handset housing having a treatment head with a treatment head surface.
  • Treatment head surface is disposed an electrode means for applying a Lontophorese current in contact of the electrode means with the scalp of a human body. Further disposed on the treatment head surface adjacent to the electrode means is a dosing means for applying an iontophoresis active agent formulation to the scalp.
  • Lontophoresis is a process which is used in particular for the introduction of active substances and nutrients into the skin, in particular into the scalp, in which active substances and nutrients are introduced into the epidermis, driven by an ion flow generated by means of direct current.
  • the iontophoresis but at a reversal of the DC direction is also suitable for the discharge of moisture and thereby with discharged waste products from the epidermis and thus for their deep cleaning.
  • specially pretreated substance mixtures are applied to the scalp part to be treated for the iontophoresis and then brought into contact with the treatment head surface together with the electrode device arranged there with a defined electrical polarity (electrically positive or electrically negative).
  • an iontophoresis direct current is introduced from the scalp part or into the scalp part.
  • the electrical polarity of the electrode device is based on the specially adapted iontophoresis active ingredient formulation used Generating a so-called positive iontophoresis or a so-called negative iontophoresis set.
  • Electrode device passed through by the DC current is electrically negatively poled, one speaks of negative iontophoresis.
  • Positive poled electrode means positive iontophoresis.
  • the lontophoresis handpiece for scalp treatment exhibits in one
  • Gripping portion of a counter electrode which is encompassed by the hand of the person whose scalp is to be iontophoretically treated.
  • the counter electrode Surrounding the counter electrode is an electrical contact between the iontophoresis handset and the arm and body of the person with the scalp lot to be treated.
  • DC circuitry exerts a driving force on ionized molecules in the iontophoresis drug formulations used.
  • This force on the ions also works in the underlying scalp layers.
  • the active substances and nutrients can be introduced in higher concentrations and deeper into the scalp parts to be treated than with a purely topical application of conventional treatment agents.
  • Conventional treatment agents are not suitable for iontophoresis use. For this purpose, especially for the iontophoresis use pretreated drug formulations are required.
  • iontophoresis provides a deep supply of the scalp with active ingredients and nutrients.
  • the negative iontophoresis is mainly used for the deep cleansing of the scalp epidermis.
  • the induced ion flux provides moisture to the scalp, which is pulled upwards from deeper layers of the scalp. In this way, slag from deeper layers of the scalp with upwards moves the scalp surface, which there mix with a washing product and wash off.
  • the negatively poled electrode means has a repulsive effect on negatively charged ionized substances. If such charged substances are present in the iontophoresis mixture mixture formulation used, they can be introduced into the scalp epidermis in the case of negative iontophoresis parallel to the above-described deep cleansing.
  • a generic iontophoresis handpiece for scalp treatment is known for example from AT386340B.
  • the known iontophoresis handpieces for scalp treatment usually operate with the DC effect described above. Often, the treatment of the scalp is made more difficult by the condition of the scalp epidermis. In such cases, the epidermis acts as a primary barrier to the establishment of ion flow throughout the scalp layers.
  • the invention is therefore the object of an improved
  • the electrode device is designed in the form of a multiplicity of electrically conductive polymer bristles arranged in the treatment head surface and surrounding the metering device.
  • the iontophoresis DC current exits from a large number of electrically conductive polymer bristles.
  • These many polymer bristles are disposed adjacent to one another in the treatment head surface and surround the metering device. The polymer bristles practice in one movement of the treatment head relative to the scalp to be treated from an abrasive effect on the epidermis of the scalp.
  • Scalp blemishes in the form of a combination of old scalp flakes with environmental particulate matter and skin lipids due to the abrasive movement of the polymer bristles away from the scalp epidermis
  • Lontophoresis- Handpiece-induced ion flow will flow better through the scalp epidermis, thus enhancing the iontophoretic deep-cleansing of the scalp epidermis through negative iontophoresis.
  • positive iontophoresis the abrasive action of the polymer bristles generated by the movement of the treatment head on the scalp area to be treated assists in the distribution and introduction of the active ingredients and nutrients for the deep care of the scalp epidermis. This also applies to the infectable in a negative iontophoresis agents and nutrients.
  • the polymer bristles preferably have diameters of up to 3 mm, more preferably up to 2 mm, and most preferably 0.5 mm to 1.5 mm. Furthermore, it is advantageous if the electrically conductive polymer bristles protrude more than five millimeters beyond the treatment head surface. The preferred length is in a range of 10 to 1 5 mm.
  • an electrically conductive rendered rubber has been found.
  • this material consist of polymer bristles or they have this material predominantly.
  • the metering device has a plurality of metering nozzles, each metering nozzle of at least four electrically conductive
  • a plurality of the electrically conductive polymer bristles in the interior of the treatment head are coupled to a mechanical vibration device such that the sections of the electrically conductive polymer bristles projecting beyond the treatment head surface can be excited to periodic vibrations with amplitudes of less than two millimeters.
  • the locally acting abrasive effect of the conductive polymer bristles is thereby significantly increased again compared to the rubbing effect caused purely by manual movement.
  • the scalp surface cleansing achieved by the vibration of the polymer bristles in conjunction with cleansing cosmetics is at the same time accompanied by the deep cleansing of the scalp epidermis caused by iontophoresis during negative iontophoresis.
  • the incoming surface cleaning facilitates and enhances the iontophoresis processes, so that a significantly better overall scalp treatment result is achieved as compared to prior art iontophoretic hand-held devices.
  • the conductive polymer bristles ensure the delivery of nutrients and active ingredients into deep layers of the scalp epidermis, which is completely painless and, compared to many alternative methods for treating the scalp, especially in hair loss, unlike the use of syringes and needles hygienic.
  • the vibration of the conductive polymer bristles promotes the microscopic processes required for iontophoresis.
  • the depth of action can be influenced and adjusted in the scalp layers. Different vibration patterns can be realized. A purely linear back and forth of the conductive polymer bristles, a circular or an oval-like movement, but also more complex movement patterns like
  • a cross shape can be realized by appropriately trained vibration devices.
  • Vibrating devices for example, piezoelectrically operated, are low available and require a relatively small amount of space. Furthermore, it is advantageous that in addition to the electrically conductive
  • Treatment head surface are arranged. These are preferably also formed of rubber. Since this rubber does not have to be rendered conductive, it is possible to use a highly pure natural product with the desired permanently elastic properties, which produces a pleasant and not too rough feeling when moving on the scalp part to be treated.
  • the parameters such as polymer bristle diameter and polymer bristle length are in the same range as previously described for the electrical
  • the electrically conductive polymer bristles and the electrically non-conductive polymer bristles of this invention can be due to the aforementioned parameters for polymer bristles material, polymer bristle diameter and
  • Polymer bristle length also synonymously referred to as polymer nappies.
  • the electrically non-conductive polymer bristles surround the electrically conductive polymer bristles on the Treatment head surface preferably on all sides.
  • the electrically conductive polymer bristles usually cause a rougher feeling in their mechanical interaction with the scalp parts to be treated. Therefore, it is advantageous for the handset user's body feel when a softer bristle area surrounds or encloses the rougher electrically conductive polymer bristles on all sides. In this constellation that offers
  • Lontophoresis handpiece for scalp treatment an optimized spatial distribution of different mechanical and electrical treatment interactions with the scalp.
  • the dosing device gives the
  • the electrically conductive polymer bristles and the electrically nonconductive polymer bristles distribute the active substance formulation on the scalp, the nutrients and active substances being painless and hygienic through the contact with the electrically conductive polymer bristles allowed iontophoresis to be introduced into the epidermis of the scalp.
  • Cleaning cosmetics achieved surface cleansing of the scalp epidermis At the same time it is accompanied by the deep cleansing of the scalp epidermis caused by negative iontophoresis.
  • Surface cleaning due to the abrasive movement of the polymer bristles facilitates and enhances the iontophoresis processes in both negative and positive iontophoresis, thus providing a significantly better overall scalp treatment result, as compared to prior art iontophoresis hand held devices is achieved.
  • positive iontophoresis the vibration of the non-conductive polymer bristles provides even better
  • Fine distribution of the iontophoresis active agent formulations on the scalp This also works in conjunction with the preferably also vibrating electrically conductive polymer nappies supportive for the iontophoretic introduction of nutrients and active ingredients.
  • the depth of action can be influenced and adjusted in the scalp layers.
  • Different vibration patterns can be realized.
  • Preferably, circular or oval-like movement patterns are used, because they are adapted
  • Vibrating devices for example, piezoelectrically operated, are low available and require a relatively small amount of space. It has proven advantageous in experiments that the vibrations of the vibrating device for the conductive and / or the non-conductive
  • a receptacle may be incorporated in the treatment head or in the handle portion of the iontophoresis handset.
  • the disposable containers are
  • the iontophoresis handset offers different iontophoresis
  • the metering device is set up and designed in such a way that the application of an iontophoresis active ingredient formulation is controlled by gas pressure.
  • the applied gas pressure above a threshold value can be used to open the nozzles with their valve function for the application of the formulation , If the gas pressure falls below the threshold again, then the nozzles close again with the pressure valve function.
  • the gas pressure control has the advantage that the iontophoresis active ingredient formulations can be completely driven out of the metering nozzles.
  • Figure 1 is a plan view of the entire treatment and functional side of the purely exemplary single embodiment of the iontophoresis handpiece for scalp treatment;
  • Figure 2 is a perspective view of the Lontophorese- handset
  • FIG. 3 is an enlarged perspective view of the iontophoresis handpiece treatment head of FIG. 1 and FIG. 2.
  • FIG. 1 shows a plan view of the entire treatment and functional side of an embodiment of the iontophoresis handpiece for scalp treatment which is shown purely by way of example. All components of this handheld lontophoresis device are arranged in a handset housing 1.
  • Handset housing 1 is ergonomically shaped so that it can be comfortably held by a user in the area of its lower half in FIG. 1. At the upper end of the handset housing 1 is the
  • Treatment head with its curved treatment head surface 10.
  • This treatment head surface 10 is in particular occupied with electrically non-conductive polymer bristles 12 and with comb bristles 14, the one in the
  • the electrically non-conductive polymer bristles 12 surround a plurality of electrically conductive polymer bristles 11, which also have a substantially cylindrical basic shape with identical or very similar proportions to the electrically non-conductive polymer bristles 12.
  • the electrically conductive polymer bristles 1 1 are shown as black cylinders.
  • the comb bristles 14, in comparison with the conductive polymer bristles 11 and the electrically non-conductive polymer bristles 12 have a slightly larger bristle diameter and are also arranged at a greater distance from each other on the treatment head surface 10.
  • the arrangement of the electrically conductive polymer bristles 11, the electrically non-conductive polymer bristles 12, the metering nozzles 13 and the comb bristles 14 can be better recognized and will be described in more detail below.
  • This polymer bristle-electrode device contacts an iontophoretic drug formulation applied from dosing nozzles 13 on the surface of a user's scalp to be treated.
  • the user holds the handset housing 1 in his hand and thereby inevitably touches on the back of the handset housing 1 and therefore not shown in Figures 1 and 2, arranged counter electrode. From a not shown in the figure 1, arranged in the handset housing 1
  • a direct current through the electroconductive polymer bristles 11 forming the electrode means is sent into the skin area to be treated and thus into the body of the user.
  • the circuit closes through the user's body and its arm flows into the holding hand.
  • the holding hand of the user is in mechanical contact with the counter electrode (not shown here) on the back of the
  • an on-off switch 6 is provided with a display device 60 arranged concentrically around this on-off switch 6.
  • display areas may be provided which indicate different treatment program modes of the iontophoresis handset or visualize, for example, the treatment duration of the current treatment.
  • Plug device 4 allows, if necessary, the production of a digital communication connection to the electronic control device of the iontophoresis handset and / or the charging of the im
  • Handset housing 1 provided accumulator.
  • a function switch 7 is arranged above the on-off switch 6.
  • FIG. 2 shows a perspective view of the iontophoresis handset of Figure 1.
  • the same components are provided with the same reference numerals. To avoid repetition, it should be emphasized that the statements made above regarding these components apply accordingly.
  • the ergonomic design of the handset housing 1 is better recognizable in this view.
  • the handset housing 1 offers space inside for other components, which are shown purely schematically.
  • an electrical energy source 2 which is usually designed as an accumulator, and a Vibrating device 3 shown.
  • the vibration device 3 ensures that both the electrically conductive polymer bristles 1 1 and the electrically non-conductive polymer bristles 12 having a frequency in the kilohertz range, z. B. with 28kHz, periodically vibrate. The resulting microscopic mechanical vibrations of the bristles significantly support the
  • the epidermis is mechanically stressed by the combination of the macroscopic user-induced movement of the bristle head with the microscopic mechanical vibrations of the bristles and thereby cleaned.
  • the combination of these two movements effectively and efficiently distributes the iontophoresis active ingredient formulation applied by the dosing nozzles 13 on the scalp surface, whose active ingredients and nutrients are introduced into the depth of the scalp epidermis by means of the electrical direct current circuit established via the conductive polymer bristles. This results in an optimized treatment of the scalp.
  • the iontophoresis active ingredient formulation is supplied to the dosing nozzles of the dosing device from a disposable container C in the form of a small capsule.
  • This capsule C contains a few milliliters of the iontophoresis active substance formulation and can be used, for example, via a flap, which is not visible in this view, on the rear side of the handset housing 1 spatially close behind the treatment head surface 10. Per application, the capsule C is usually to change.
  • a gas pressure device also not shown here allows the controlled application of
  • FIG. 3 shows an enlarged plan view of the treatment head surface 10 from the iontophoresis handpiece for scalp treatment from FIG. 1 and FIG. 2. Identical components are provided with the same reference numerals. Around To avoid repetition, it should be emphasized that the statements made above regarding these components apply accordingly.
  • the applied iontophoresis active ingredient formulation is applied to the scalp by the metering nozzles 13 according to their arrangement along a line.
  • the vibration device preferably for all polymer bristles generated microscopic movement of the multifunctional bristle ensemble distributes the formulation and massages them on the
  • the comb bristles 14 cause a kind of pre-structuring of the polymer bristle ensemble consisting of the electrically non-conductive polymer bristles 12 and the electrically conductive

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention concerne un appareil d'ionophorèse portatif destiné au traitement du cuir chevelu et comportant un corps (1) d'appareil portatif, ledit appareil portatif étant muni d'une tête de traitement présentant une surface (10) sur laquelle est placé un dispositif d'électrodes destiné à appliquer un courant électrique d'ionophorèse lorsqu'il est au contact du cuir chevelu, et un dispositif de dosage destiné à appliquer une formulation de principe actif d'ionophorèse sur le cuir chevelu étant disposé au voisinage du dispositif d'électrodes. Selon l'invention, le dispositif d'électrodes se présente sous la forme d'une pluralité de poils polymères (11) électroconducteurs disposés dans la surface (10) de la tête de traitement.
PCT/DE2018/100806 2017-09-25 2018-09-24 Appareil d'ionophorèse portatif pour le traitement du cuir chevelu WO2019057250A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE112018005438.1T DE112018005438A5 (de) 2017-09-25 2018-09-24 Iontophorese-handgerät zur kopfhaut-behandlung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017122198.0 2017-09-25
DE102017122198 2017-09-25

Publications (2)

Publication Number Publication Date
WO2019057250A1 true WO2019057250A1 (fr) 2019-03-28
WO2019057250A8 WO2019057250A8 (fr) 2019-06-20

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PCT/DE2018/100806 WO2019057250A1 (fr) 2017-09-25 2018-09-24 Appareil d'ionophorèse portatif pour le traitement du cuir chevelu

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DE (1) DE112018005438A5 (fr)
WO (1) WO2019057250A1 (fr)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386340B (de) 1986-05-06 1988-08-10 Vizelyi Gabor Iontophoresegeraet
DE3853068D1 (de) 1987-04-08 1995-03-23 Toray Silicone Co Elektroleitfähige Silikongummipartikel.
DE3919869C2 (de) 1988-06-17 1995-05-11 Shinetsu Polymer Co Verfahren zur Herstellung eines integrierten Gummiartikels mit elektrisch nichtleitenden und leitenden Teilen
JP2000236932A (ja) * 1999-02-24 2000-09-05 Satellite Intelligence:Kk 電子髪梳き具
US20020010414A1 (en) * 1999-08-25 2002-01-24 Coston Anthony F. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
GB2390023A (en) * 2002-06-27 2003-12-31 Kieron Loy Iontophoretic hairbrush with handle return electrode
US20100331810A1 (en) * 2009-02-12 2010-12-30 Mir Imran Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
JP4739698B2 (ja) * 2004-06-29 2011-08-03 有子 木村 マッサージ器具
WO2017069509A1 (fr) * 2015-10-19 2017-04-27 (주)네추럴리즘 Dispositif pour le soin de la peau

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386340B (de) 1986-05-06 1988-08-10 Vizelyi Gabor Iontophoresegeraet
DE3853068D1 (de) 1987-04-08 1995-03-23 Toray Silicone Co Elektroleitfähige Silikongummipartikel.
DE3919869C2 (de) 1988-06-17 1995-05-11 Shinetsu Polymer Co Verfahren zur Herstellung eines integrierten Gummiartikels mit elektrisch nichtleitenden und leitenden Teilen
JP2000236932A (ja) * 1999-02-24 2000-09-05 Satellite Intelligence:Kk 電子髪梳き具
US20020010414A1 (en) * 1999-08-25 2002-01-24 Coston Anthony F. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
GB2390023A (en) * 2002-06-27 2003-12-31 Kieron Loy Iontophoretic hairbrush with handle return electrode
JP4739698B2 (ja) * 2004-06-29 2011-08-03 有子 木村 マッサージ器具
US20100331810A1 (en) * 2009-02-12 2010-12-30 Mir Imran Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
WO2017069509A1 (fr) * 2015-10-19 2017-04-27 (주)네추럴리즘 Dispositif pour le soin de la peau

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Publication number Publication date
WO2019057250A8 (fr) 2019-06-20
DE112018005438A5 (de) 2020-09-03

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