WO2018131025A2 - Didactic game learn about your dna - Google Patents
Didactic game learn about your dna Download PDFInfo
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- WO2018131025A2 WO2018131025A2 PCT/IB2018/053599 IB2018053599W WO2018131025A2 WO 2018131025 A2 WO2018131025 A2 WO 2018131025A2 IB 2018053599 W IB2018053599 W IB 2018053599W WO 2018131025 A2 WO2018131025 A2 WO 2018131025A2
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- dna
- double
- strands
- replication process
- horizontal support
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/26—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for molecular structures; for crystallography
Definitions
- the present invention may be included in the technical field of educational or demonstration devices, in particular in the field of biology and genetics teaching.
- the object of the invention refers to a didactic device for learning the structure of the deoxyribonucleic acid (DNA, hereinafter) and the replication process thereof by means of assembling structures, thus allowing relating the structures with concepts and developing the user skills such as observation, comparison, synthesis or analysis.
- DNA deoxyribonucleic acid
- Didactic devices are an efficient strategy for achieving knowledge learning, both of concepts and processes and which help improving attitudes and competences of the user.
- the present invention provides a didactic device for learning about the DNA structure and the replication process thereof by assembling structures, thus allowing relating the structures with concepts and developing the user skills such as observation, comparison, synthesis or analysis of these structures.
- an aspect of the present invention refers to a didactic device for learning the DNA structure and the replication process thereof comprising:
- the moving sections comprise, at least, two outer sections for mounting the initial double-stranded DNA and, at least, two inner sections for mounting complementary DNA strands in the replication process.
- FIG 1 - It is a view of all the assembling pieces of the didactic device.
- FIG 2 - It is a front view of the double-stranded DNA.
- FIG 3 - It is a front view of the double-stranded DNA at the beginning of the replication.
- FIG 4 - It is a front view of the double-stranded DNA during the replication process.
- FIG 5 - It is a front view of the separation of the two strands of the DNA in the replication process.
- FIG 6 - It is a front view of the synthesis of the DNA complementary strands in the replication process.
- FIG 7 - It is a front view of the replicated DNA molecule.
- FIG 8 - It is a side view of the double rack strip.
- FIG 9 - It is a front and side view of the support for the complementary strand being synthesized in the opposite direction.
- FIG 1 - It is a view of all the assembling pieces of the didactic device comprising a container for keeping the didactic device (1 a), a manual including instructions for mounting thereof and the game rules (1 b), a horizontal support acting as a base for mounting the structures (1 c) with the outer (1 ch-1 ) and inner (1 ch-2) moving sections, vertical supports for DNA strands (1 d) and for DNA complementary strands in the replication (1 e) and the double rack strip (1 f); it also shows pieces representing: the nitrogen bases: cytosine (1 g), guanine (1 h), thymine (1 i) and adenine (1j), the deoxyribose sugar (1 k), the phosphate groups (11), enzymes such as helicase (1 m), DNA polymerase (1 n), topoisomerase (1 n) and ligase (1 q), bonds between base pairs for representing double and triple bonds (1 o), vertical supports for the synthesized complementary strand in the opposite direction to the replication fork (1p)
- FIG 2 - It shows a front view of the double-stranded DNA structure wherein the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h) are represented being bonded by double and triple bonds (1o) respectively, together with sugars (1k) and phosphate groups (11) in the vertical supports (1d) and the sliding base (1c).
- FIG 3 - It shows a front view of the double-stranded DNA structure at the beginning of replication, showing the strands with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h) being separated, together with sugars (1k), phosphate groups (11) and helicase (1m) in the vertical supports (1d) and the sliding base (1c).
- FIG 4 - It is a front view of the double-stranded DNA structure during the replication process showing the strands with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h), together with sugars (1k), phosphate groups (11), helicase (1m), topoisomerase (1n) and SSB proteins (1r) in the vertical supports (1d) and the sliding base (1c).
- FIG 5 - It is a front view of the separation of the two DNA strands in the replication process showing the strands being already separated with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h), together with sugars (1k), phosphate groups (11), helicase (1m) and SSB proteins (1r) in the vertical supports (1d) and the sliding base (1c).
- FIG 6 - It is a front view of the DNA complementary strands synthesis in the replication process and the direction (1s) thereof, showing the double strands of the DNA being duplicated with the base pairs adenine (1j) with thymine (1i) and cytosine (1 g) with guanine (1 h), together with sugars (1 k), phosphate groups (11) thanks to the DNA polymerase (1 n) action and the ligase (1 q) in the vertical supports of DNA strands (1 d), vertical supports of the complementary strands (1 e) and the sliding base (1 c).
- FIG 7 - It is a front view of the replicated DNA molecule, showing the two structures of double-stranded DNA being duplicated where the base pairs adenine (1j) with thymine (1 i) and cytosine (1 g) with guanine (1 h) are represented being bonded by double and triple bonds (1 o) respectively, together with sugars (1 k) and phosphate groups (11) in the vertical supports of the DNA strands (1 d), vertical supports of the complementary strands (1 e) and the sliding base (1 c).
- FIG 8 Side view of the double rack strip (1 f).
- FIG 9 - It is a front and side view of the support for the synthesized complementary strand in the opposite direction (1 p).
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Abstract
Didactic device for learning the DNA structure and the replication process by means of assembling structures comprising: a sliding horizontal support acting as a base for the DNA structure for assembling said structure, a double rack strip and pieces representing the individual DNA components and the replication process.
Description
DIDACTIC GAME LEARN ABOUT YOUR DNA
OBJECT OF THE INVENTION The present invention may be included in the technical field of educational or demonstration devices, in particular in the field of biology and genetics teaching.
More specifically, the object of the invention refers to a didactic device for learning the structure of the deoxyribonucleic acid (DNA, hereinafter) and the replication process thereof by means of assembling structures, thus allowing relating the structures with concepts and developing the user skills such as observation, comparison, synthesis or analysis. BACKGROUND OF THE INVENTION
Didactic devices are an efficient strategy for achieving knowledge learning, both of concepts and processes and which help improving attitudes and competences of the user.
Existing didactic devices about DNA are mostly centred on recognizing the DNA components, its structure or the process of the synthesis of proteins. Document US2004/1 13362 describes a board game for learning concepts about the DNA such as the structure thereof. Document US3804417 describes a didactic game for learning concepts about the DNA and the protein translation process and the functionality thereof in the human body, similarly as document CN2103844 which also describes an educational model for teaching the protein synthesis process starting from DNA molecules.
Therefore, considering the aforementioned documents it is necessary to find alternatives directed to educational devices or models for learning both the
DNA structure and the semiconservative replication process thereof, based on base complementarity.
DESCRIPTION OF THE INVENTION
The present invention provides a didactic device for learning about the DNA structure and the replication process thereof by assembling structures, thus allowing relating the structures with concepts and developing the user skills such as observation, comparison, synthesis or analysis of these structures.
Therefore, an aspect of the present invention refers to a didactic device for learning the DNA structure and the replication process thereof comprising:
- a horizontal support,
- at least two movable sections located at the horizontal support,
- at least two sliding vertical supports located at the movable sections of the horizontal support for assembling the pieces so as to form the structures of the DNA strands,
- individual pieces of the components of the DNA strands that can be assembled both to the sliding vertical supports for fastening thereof and sliding through the horizontal support, and to other individual pieces of the DNA components so as to form the complementary strand in the double-stranded DNA, and
- a double vertical rack strip which is inserted between the double- stranded DNA and allows separating both DNA strands so as to represent the beginning of the replication process.
In a preferred embodiment the moving sections comprise, at least, two outer sections for mounting the initial double-stranded DNA and, at least, two inner sections for mounting complementary DNA strands in the replication process.
DESCRIPTION OF THE DRAWINGS
FIG 1 - It is a view of all the assembling pieces of the didactic device.
FIG 2 - It is a front view of the double-stranded DNA.
FIG 3 - It is a front view of the double-stranded DNA at the beginning of the replication.
FIG 4 - It is a front view of the double-stranded DNA during the replication process.
FIG 5 - It is a front view of the separation of the two strands of the DNA in the replication process.
FIG 6 - It is a front view of the synthesis of the DNA complementary strands in the replication process.
FIG 7 - It is a front view of the replicated DNA molecule.
FIG 8 - It is a side view of the double rack strip.
FIG 9 - It is a front and side view of the support for the complementary strand being synthesized in the opposite direction.
PREFERRED EMBODIMENT OF THE INVENTION
The following is the description of a preferred embodiment of the invention based on the attached figures.
FIG 1 - It is a view of all the assembling pieces of the didactic device comprising a container for keeping the didactic device (1 a), a manual including instructions for mounting thereof and the game rules (1 b), a horizontal support acting as a base for mounting the structures (1 c) with the outer (1 ch-1 ) and inner (1 ch-2) moving sections, vertical supports for DNA strands (1 d) and for DNA complementary strands in the replication (1 e) and the double rack strip (1 f); it also shows pieces representing: the nitrogen bases: cytosine (1 g), guanine (1 h), thymine (1 i) and adenine (1j), the deoxyribose sugar (1 k), the phosphate groups (11), enzymes such as helicase (1 m), DNA polymerase (1 n), topoisomerase (1 n) and ligase (1 q), bonds between base pairs for representing double and triple bonds (1 o), vertical supports for the synthesized
complementary strand in the opposite direction to the replication fork (1p) opening, SSB (1r) proteins and the synthesis direction (1s).
FIG 2 - It shows a front view of the double-stranded DNA structure wherein the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h) are represented being bonded by double and triple bonds (1o) respectively, together with sugars (1k) and phosphate groups (11) in the vertical supports (1d) and the sliding base (1c). FIG 3 - It shows a front view of the double-stranded DNA structure at the beginning of replication, showing the strands with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h) being separated, together with sugars (1k), phosphate groups (11) and helicase (1m) in the vertical supports (1d) and the sliding base (1c).
FIG 4 - It is a front view of the double-stranded DNA structure during the replication process showing the strands with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h), together with sugars (1k), phosphate groups (11), helicase (1m), topoisomerase (1n) and SSB proteins (1r) in the vertical supports (1d) and the sliding base (1c).
FIG 5 - It is a front view of the separation of the two DNA strands in the replication process showing the strands being already separated with the double rack strip (1f) and the base pairs adenine (1j) with thymine (1i) and cytosine (1g) with guanine (1h), together with sugars (1k), phosphate groups (11), helicase (1m) and SSB proteins (1r) in the vertical supports (1d) and the sliding base (1c). FIG 6 - It is a front view of the DNA complementary strands synthesis in the replication process and the direction (1s) thereof, showing the double strands of the DNA being duplicated with the base pairs adenine (1j) with thymine (1i) and
cytosine (1 g) with guanine (1 h), together with sugars (1 k), phosphate groups (11) thanks to the DNA polymerase (1 n) action and the ligase (1 q) in the vertical supports of DNA strands (1 d), vertical supports of the complementary strands (1 e) and the sliding base (1 c).
FIG 7 - It is a front view of the replicated DNA molecule, showing the two structures of double-stranded DNA being duplicated where the base pairs adenine (1j) with thymine (1 i) and cytosine (1 g) with guanine (1 h) are represented being bonded by double and triple bonds (1 o) respectively, together with sugars (1 k) and phosphate groups (11) in the vertical supports of the DNA strands (1 d), vertical supports of the complementary strands (1 e) and the sliding base (1 c).
FIG 8 - Side view of the double rack strip (1 f).
FIG 9 - It is a front and side view of the support for the synthesized complementary strand in the opposite direction (1 p).
Claims
1 . Didactic device for learning the DNA structure and the replication process thereof:
- a horizontal support,
- at least two moving sections located in the horizontal support,
- at least two sliding vertical supports located in the moving sections of the horizontal support for assembling the pieces so as to form the DNA strands structures,
- individual pieces of the components of the DNA strands assembling both to the sliding vertical supports for fastening thereof and sliding through the horizontal support, and to other individual pieces of the DNA components so as to form the complementary strand in the double- stranded DNA structure, and
- a double vertical rack strip being inserted between the double strand of the DNA and allowing separation of the two DNA strands so as to represent the beginning of the replication process.
2. Didactic device according to claim 1 , wherein the moving sections comprise, at least, two outer sections for mounting the initial double- stranded DNA, and at least two inner sections for mounting complementary DNA strands in the replication process.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PA92135 | 2018-04-20 | ||
| PA9213501 | 2018-04-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2018131025A2 true WO2018131025A2 (en) | 2018-07-19 |
| WO2018131025A3 WO2018131025A3 (en) | 2018-11-29 |
Family
ID=62839365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2018/053599 Ceased WO2018131025A2 (en) | 2018-04-20 | 2018-05-22 | Didactic game learn about your dna |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2018131025A2 (en) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3296714A (en) * | 1964-09-04 | 1967-01-10 | Eastview Corp | Molecular models |
| US3594924A (en) * | 1969-06-25 | 1971-07-27 | Nasco Ind Inc | Dna-rna teaching aid |
| US4184271A (en) * | 1978-05-11 | 1980-01-22 | Barnett James W Jr | Molecular model |
| US6036497A (en) * | 1998-07-25 | 2000-03-14 | Langmuir; David B. | Dynamic model of the DNA molecule |
| US7401705B2 (en) * | 2003-12-31 | 2008-07-22 | Rubbermaid Incorporated | Organizer system and vertical upright with rollers |
| US9842514B2 (en) * | 2014-02-19 | 2017-12-12 | Milwaukee School Of Engineering | Dynamic deoxyribonucleic acid (DNA) models and kits |
| US9779638B2 (en) * | 2014-11-12 | 2017-10-03 | Massachusetts Institute Of Technology | Educational building blocks to model DNA and RNA structures |
-
2018
- 2018-05-22 WO PCT/IB2018/053599 patent/WO2018131025A2/en not_active Ceased
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| Publication number | Publication date |
|---|---|
| WO2018131025A3 (en) | 2018-11-29 |
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