WO2018178942A1 - Method and system of displaying a real-time glucose reading with an alarm clock - Google Patents
Method and system of displaying a real-time glucose reading with an alarm clock Download PDFInfo
- Publication number
- WO2018178942A1 WO2018178942A1 PCT/IB2018/052218 IB2018052218W WO2018178942A1 WO 2018178942 A1 WO2018178942 A1 WO 2018178942A1 IB 2018052218 W IB2018052218 W IB 2018052218W WO 2018178942 A1 WO2018178942 A1 WO 2018178942A1
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- Prior art keywords
- glucose
- alarm clock
- reading
- displaying
- level readings
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
- A61B5/743—Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
Definitions
- PCT Patent Cooperation Treaty
- the present invention generally relates to a method of displaying a real-time glucose reading with an alarm clock. More specifically, the alarm clock is equipped with a projector that projects a scatter plot showing the history and the future trend of the glucose-level.
- Conventional glucose monitors use a receiver or a smartphone to display the realtime glucose-level readings.
- the numerical value of the real-time glucose-level is displayed on the screen of the receiver or the smartphone. If the glucose-level reaches a dangerously high or dangerously low value, the smartphone or the receiver outputs an alert prompting the user to take corrective action. Dangerously high or dangerously low glucose-level can lead to seizures, brain damage, and is often a very life-threatening situation. Thus, it is imperative that the user is properly notified of the abnormal glucose- level so that corrective actions can be taken. Preferably, the user should take corrective action as soon as the glucose-level starts trending too high or too low.
- the receiver or the smartphone is the only means of notifying the user of the real-time glucose-level. This problem is exacerbated when the user goes to sleep, since most users do not go to sleep while carrying their smartphone or their receiver. Thus, if the user wants to see how the glucose-level is trending, the user must physically reach for the smartphone or the receiver. However, reaching for the receiver or the smartphone while lying on the bed is cumbersome, uncomfortable, and can disturb sleep.
- the present invention is a projector alarm clock designed to suit the lives of users suffering from Type 1 and Type 2 diabetes.
- the alarm clock takes the data from the glucose monitor that the user is wearing and displays this data through the projector on the alarm clock and onto the ceiling or the wall.
- the alarm clock therefore enables the user to glance quickly at the projection without needing to fumble to their smartphones or their receivers at night. Since the glucose-level is projected onto the wall, anyone walking past the bedroom can also quickly look at the glucose-level. For example, if the user is a child, a parent or caretaker can quickly glance at the wall while the child is sleeping to see the trend of the glucose-level. This provides peace of mind to the parent with minimal disruption for the child.
- the alarm clock would also have standard features found in a common bedside alarm clock, such as time, date, temperature, wake alarm, etc.
- the alarm clock projects the numerical value of the real-time glucose-level and a scatter plot taken over a three- hour time period showing how the glucose-level is trending. This information is projected in large, easy to read graphics on the bedroom wall, ceiling, or floor. The user can thus glance at the projection while lying on the bed without significantly altering his posture. The user can also use the trending information to determine whether or not he or she would soon need to get up to make an insulin correction or consume additional carbohydrates.
- FIG. 1 is a front perspective view of the alarm clock projecting the real-time glucose- level reading and the scatter plot of glucose-level readings onto the wall of the bedroom.
- FIG. 2 is a schematic view of the present invention showing the glucose monitor connected to the portable PC device, the remote server, and the microprocessor in the alarm clock.
- FIG. 3 is a flow chart showing the order of operation of Step A through Step G.
- FIG. 4 is a flow chart showing the sub-processes of Step G, wherein the physically- comfortable electronic band is used to alert the user.
- FIG. 5 is a flow chart showing the sub-processes of Step G, wherein the electronic accessory and the electronic socket.
- FIG. 6 is a flow chart showing the sub-processes of Step G, wherein the physical display is provided on the alarm clock.
- FIG. 7 is a flow chart showing the sub-processes of Step G, wherein the computing system is a microprocessor.
- FIG. 8 is a flow chart showing the sub-processes of Step G, wherein the user interface is a plurality of hardwired buttons.
- FIG. 9 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device which also outputs the alert when an outlier reading is identified.
- FIG. 10 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the portable PC device outputs the alert when an outlier reading is identified.
- FIG. 11 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the patient profile is linked to at least one related profile.
- FIG. 12 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the related PC device outputs the alert when an outlier reading is identified.
- the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the related PC device outputs the alert when an outlier reading is identified.
- the present invention is a method and system of displaying a real-time glucose reading with an alarm clock. More specifically, the alarm clock obtains a set of glucose- level readings from a glucose monitor and uses a projector to project the set of glucose- level readings onto the wall or the ceiling of a room. If the glucose-level trends dangerously low or dangerously high, the alarm clock outputs visual and audible alerts notifying the user to take corrective action.
- the alarm clock also allows the user to preempt an alert by providing a scatter plot showing the trend of the glucose level. The scatter plot shows the history and the future trend of the glucose-level, thereby allowing the user to correct the glucose-level before an alert is activated.
- the present invention also includes alternate minimally invasive alerting device. More specifically, the vibrating bands worn around the arm or legs notify the user of dangerous glucose-levels without disturbing the other occupants of the bed. Similarly, the present invention also allows an existing electronic device to be used as the preferred alerting method.
- the system for the present invention is provided with a computing system, a glucose monitor, and an alarm clock, wherein an acceptable glucose range is stored on the computing system (Step A).
- the alarm clock is designed as a minimally invasive method of notifying the user of their real-time glucose-level.
- the alarm clock is configured to be placed in the bedroom, in clear view of the user who may be laying on the bed.
- the alarm clock generates an easily visible and easily readable projection of the real-time glucose-level reading onto the wall of the bedroom. The user can thus quickly glance at the projection while lying on the bed, without having to move his or her body, or having to reach for the smartphone or the receiver.
- the computing system may be integrated into the alarm clock, a mobile computing device, or into a remote server in wireless communication with the alarm clock.
- the glucose monitor refers to a non- invasive, minimally invasive, or invasive continuous glucose monitor (CGM) that comprises a transmitter and a sensor.
- CGM non-invasive, minimally invasive, or invasive continuous glucose monitor
- the sensor is subcutaneously inserted into the user's belly, arm, back, or the leg, whereby the sensor reads the glucose-level readings in the surrounding fluids.
- the sensor employs an enzyme called glucose oxidase to convert glucose to hydrogen peroxide.
- the hydrogen peroxide generates an electrical signal which is converted into a glucose-level reading.
- Several chemical layers applied over the glucose oxidase protect against the fluids inside the user's body that can dilute the glucose oxide.
- the glucose monitor converts the electrical signals to the set of the glucose-level readings.
- the conversion of the electrical signal into a glucose-level may be offloaded to the computing system.
- the set of glucose-level readings comprises a plurality of glucose-level readings taken over a period of time. The time interval between each of the plurality of glucose-level readings is constant.
- the set of glucose-level readings is recorded in terms of the concentration of glucose in the blood stream.
- each glucose- level reading may be measured in milligrams per decalitre (mg/dL). Further, the frequency at which the glucose-level readings are taken may change in other
- the system of the present invention is used to continuously receive the set of glucose-level readings through the glucose monitor (Step B).
- the set of glucose-level readings is then continuously transmitted to the computing system.
- the transmitter relays the set of glucose-level readings from the glucose monitor to the computing system (Step C).
- the transmitter wirelessly and continuously transmits the set of glucose-level readings to the computing system.
- the transmitter preferably utilizes a wireless technology standard enabling ultra-high frequency (UHF) radio communication (e.g. Wi-Fi).
- UHF ultra-high frequency
- the step of interpreting and analyzing the set of glucose-level readings is off-loaded to the computing system through the wireless transmission.
- the computing system parses through the set of glucose-level readings with the computing system in order to identify at least one outlier reading within the set of glucose-level readings, wherein the outlier reading is outside of the acceptable glucose range (Step D).
- the computing system is equipped with a user interface, which allows the user to set the acceptable glucose range and help identify the outlier reading.
- the outlier reading is a reading from the set of glucose-level readings that is outside the acceptable glucose range.
- the user sets the acceptable glucose range between a dangerously high and dangerously low glucose-level reading. Thus, if the outlier reading is identified, the glucose-level reading is dangerously high or dangerously low and the user must make an insulin correction immediately.
- the set of glucose-level readings is relayed from the computing system to the alarm clock (Step E).
- the computing system also archives and stores the historical set of glucose-level readings taken over the lift of the glucose monitor.
- the set of glucose-level readings may be relayed via an internet connection or a cellular network depending on the type of computing system being utilized.
- a projector of the alarm clock displays the set of glucose-level readings (Step F).
- the projector is mounted to the alarm clock via a swivel bracket which allows the user to point the projector to the walls, ceiling, or the floor of the bedroom.
- the projector projects the real-time glucose-level reading and a scatter plot showing the change in the glucose-level over time onto the wall.
- the real-time glucose-level is the numerical value of the glucose-level, measured in mg/dL, displayed in illuminated letters against a black background.
- the scatter plot shows the glucose-level in the Y-axis and the time in the X-axis and may have a line of best fit going through the data points.
- the scatter plot is illuminated against a black background and is positioned next to the real-time glucose-level reading.
- the scatter plot displays data points taken over a three- hour interval.
- the time interval of the scatter plot can be increased or decreased via the computing system.
- the real-time glucose-level reading and the scatter plot preferably fills a substantial portion of the wall, ceiling, or floor, allowing the user to quickly glance at the projection while lying or resting on the bed.
- the scatter plot and the numerical value is brightly illuminated against a black background.
- the numerical value is positioned adjacent to the scatter plot.
- the alarm clock is also designed to output an alert with the alarm clock, if the outlier reading is identified by the computing system (Step G).
- the outlier reading measures the concentration of glucose in the bloodstream.
- there is an upper-bound outlier when the glucose-level is dangerously high, and a lower-bound outlier reading, when the glucose- level is dangerously low.
- a user interface of the computing system allows the user or another operator of the present invention to change and set the acceptable glucose range. More specifically, the user interface allows the user to input numerical values of the dangerously high and dangerously low glucose-level reading. The numerical value may be the glucose-level concentration measured in mg/dL or any other appropriate unit.
- the user may enter 130 mg/dL for the upper-bound acceptable glucose range and 70 mg/dL for lower-bound of the acceptable glucose range.
- the acceptable glucose range may change dynamically, according to the programmed rules that take various physical readings into account.
- the alarm clock outputs an alert.
- the alarm clock outputs an audible alert that the user can hear without glancing at the alarm clock.
- the audible alert may be loud enough to disturb the user from sleep.
- the alarm clock may also project visual alerts such as flashing lights, changing colors, and warning messages to notify the user.
- the user controls the severity and the type of the alerts through the user interface.
- the computing system may also send alert messages to the user's close associates. The alert messages may be sent via the internet, cellular networks, or a local area connection.
- the present invention also relates to providing a non-invasive method of alerting the user by providing a physically-comfortable electronic band, wherein the physically-comfortable electronic band is communicably coupled to the alarm clock.
- the physically-comfortable electronic band is preferably a wrist band made of soft plastic or fabric that is pleasant to the touch.
- the physically-comfortable alarm clock is intended to remain on the user for prolonged periods of time and is thus designed to accommodate the user's daily activities.
- the physically-comfortable electronic band may be waterproof, dustproof, and capable of operating for several days without being recharged.
- the physically-comfortable electronic band provides a non-invasive way of alerting the user while the user is sleeping.
- the physically-comfortable electronic band wirelessly connects to the alarm clock via a UHF radio wave connection. Instead of sounding out a visible or audible alert through the alarm clock and risking waking other occupants of the bedroom, the physically- comfortable electronic band alerts only the user. More specifically, the physically- comfortable electronic band starts vibrating if the outlier reading is identified by the computing system after parsing through the set of glucose-level readings in Step D.
- the physically-comfortable alarm clock may be wirelessly connected to the computing system directly, via the internet or a cellular network.
- another non-invasive alerting method involves providing at least one electronic accessory and at least one electronic socket, wherein the electronic socket is operatively connected to the alarm clock, and wherein the electronic accessory is plugged into the electronic socket.
- the electronic socket selectively allows the flow of electricity from an existing power outlet to the electronic device.
- the electronic socket powers the electronic accessory if the outlier reading is identified by the computing system in Step D.
- the alarm clock signals the electronic socket to allow the flow of electricity from the power outlet to the electronic device.
- the signal is preferably sent through a wireless connection between the alarm clock and the electronic socket.
- the preferred embodiment of the electronic socket has a plug end that connects to an existing wall-mounted power outlet.
- the electronic accessory also has a plug end that is adapted to connect into the electronic socket.
- the electronic accessory refers to an existing electronic device that a user can choose to alert themselves.
- the electronic accessory may be a Fan set to high, or a radio with the volume turned up.
- the electronic accessory may be an alerting light.
- the alert from the electronic device substitutes the alert from the alarm clock.
- both the electronic device and the alarm clock may both alert the user. Referring to FIG.
- a physical display is provided, wherein the electronic display is operatively integrated into the alarm clock.
- the preferred embodiment of the alarm clock is a rectangular prism with slanted sidewall, with the physical display integrated into one of the slanted sidewalls.
- the physical display displays the set of glucose-level readings during Step F.
- the physical display is a liquid crystal display (LCD) or light emitting diode (LED) screen that displays the time, the scatter plot, and the numerical value of the real-time glucose-level.
- LCD liquid crystal display
- LED light emitting diode
- the computing system is contained within the alarm clock itself.
- a microprocessor is provided as the computing system, wherein the microprocessor is operatively integrated into the alarm clock.
- the microprocessor is programmed to interpret the set of glucose-level readings transmitted from the glucose monitor and control the alarm clock accordingly.
- the set of glucose-level readings is directly communicated from the glucose monitor to the alarm clock.
- the set of glucose-level readings is communicated over a UHF radio wave connection between the glucose monitor and the microprocessor.
- the user interface is provided as a plurality of hardwired buttons, wherein each hardwired button is operatively integrated into the alarm clock and is associated to a corresponding setting adjustment for the alarm clock.
- the microprocessor is programmed to detect the activation of a specific button, wherein the specific button is from the plurality of hardwired buttons.
- the microprocessor then executes the corresponding setting adjustment for the specific button.
- the corresponding setting adjustment refers to various settings of the alarm clock such as the UHF radio wave connection between the glucose monitor and the alarm clock, the outlier reading value, the range of outlier readings, and the connection between the alarm clock, the electronic socket, the electronic accessory, and the physically-comfortable electronic band.
- an application that runs on a smartphone may be used to adjust the settings of the alarm clock.
- the application may wirelessly communicate with the microprocessor via a UHF radio wave, a Wi-Fi, or a cellular network to communicate the desired adjustments to the settings of the alarm clock.
- the computing system may be contained in the smartphone itself. More generically, a portable personal computing (PC) device is the computing system, wherein the portable PC is communicably coupled to the alarm clock.
- the portable PC device can be, but is not limited to, a smartphone, a laptop, a tablet, or similar client computing devices.
- the portable PC device runs an application allowing the portable PC device to connect to the glucose monitor and relay the set of glucose-level readings to the alarm clock.
- the set of glucose readings is indirectly communicated from the glucose monitor, through the portable PC device, and to the alarm clock.
- the glucose monitor uses UHF radio wave to connect to the portable PC device
- the portable PC device may use Wi-Fi, a cellular network, or a similar wireless communication standard to connect to the alarm clock.
- the user interface is integrated into the application. The user interface allows the user to adjust the settings of both the glucose monitor and the alarm clock.
- the application also prompts the user to view the set of glucose-level readings through the portable PC device.
- the set of glucose-level readings is displayed with the portable PC device, only if the portable PC device confirms to view the set of the glucose-level readings.
- the application displays the numerical values of the set of glucose-level readings along with the accompanying continuous line graph on the screen of the portable PC device itself. If the outlier reading is identified during Step D, the portable PC device activates the alarm clock which outputs the alert. Additionally, the application is also capable of outputting the alert with the portable PC device, if the outlier reading is identified by the computing system.
- the portable PC device may output both a visible alert and an audible alert simultaneously.
- the portable PC device is connected to at least one remote server, wherein the portable PC device is communicably coupled to the remote server, and wherein the remote server is communicably coupled to the alarm clock.
- the portable PC device and the at least one remote server are used to enable a cloud computing platform.
- the cloud computing platform comprises a network of servers communicating with a plurality of portable PC devices over the internet.
- the network of servers stores, manages and processes, large datasets of glucose-level readings generated by the plurality of portable PC devices.
- the portable PC device is connected to the remote server over a wireless local area network (WLAN).
- WLAN wireless local area network
- the portable PC device relays the set of glucose-level readings from the glucose monitor to the remote server.
- the remote server is used to manage a patient profile.
- the patient profile transmits the real-time glucose-level readings to the alarm clock and archives glucose- level readings taken over the life of the glucose-monitor. Additionally, the patient profile also may also contain the user's medical history.
- the set of glucose readings from the glucose monitor is indirectly communicated from the glucose monitor, through the portable PC device, through the remote server, and to the alarm clock. To achieve this, the alarm clock is connected to remote server over the WLAN.
- the portable PC device offloads the storage and the processing of the set of glucose-level readings to the remote server.
- the set of glucose-level readings is stored on the remote server as part of the patient profile.
- the user can access the set of glucose-level readings via an application that runs on the portable PC device.
- the application prompts the user to view the set of glucose - level readings through the portable PC device. If the user confirms to view the set of glucose-level readings, the set of glucose-level readings is displayed with the portable PC device.
- the set of glucose-level readings is displayed on the screen of the portable PC device as a continuous line graph or a scatter plot with a line of best fit going through the data points.
- the numerical value of the real-time glucose-level concentration is also displayed.
- the application also allows the user to set or change the acceptable glucose range which identifies the outlier reading. If the outlier reading is identified by the computing system in Step D, the portable PC device outputs the alert. Since the computing system is distributed between the portable PC device and the remote server, either the portable PC device or the remote server may identify the outlier reading.
- the cloud computing platform may also allow the user to share the set of glucose-level readings with one or more associates.
- Associates refers to the user's friends and family members.
- the associate To access the set of glucose-level readings, the associate must open at least one related profile which is managed by the remote server.
- the related profile is linked to the patient profile and is associated to a related PC device.
- the related PC device is used by the associate to communicate with the remote server. Unlike the patient profile, the related profile includes only the minimal amount of personal information about the associate.
- the related profile is granted the same privileges as the patient profile, and the associate can view the user's set of glucose-level readings stored in the computing system.
- the associate controls the associate profile through an application running on the related PC device.
- the application may prompt to view the set of glucose- level readings through the related PC device. If the related PC device confirms to view the set of glucose-level readings, the set of glucose-level readings is displayed on the related PC device.
- the set of glucose-level readings may be displayed as a continuous line graph, a scatter plot, or a numerical value of the real-time glucose-level reading.
- the application also outputs an alert with the related PC device, if the outlier reading is identified by the computing system in Step D.
- the alert may be visual or audible alert that overrides any application that is currently running on the related PC device.
- the related PC device may output an audible alarm and flashing lights to alert the associate.
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Abstract
A method and system of displaying a real-time glucose reading includes a computing system, a glucose monitor, and an alarm clock, wherein an acceptable glucose range is stored on the computing system. The method includes the steps of continuously receiving a set of glucose-level readings through the glucose monitor; relaying the set of glucose-level readings from the glucose monitor to the computing system; parsing through the set of glucose-level readings with the computing system in order to identify at least one outlier reading within the set of glucose-level readings, wherein the outlier reading is outside of the acceptable glucose range; relaying the set of glucose-level readings from the computing system to the alarm clock; displaying the set of glucose- level readings with a projector of the alarm clock; outputting an alert with the alarm clock, if the outlier reading is identified by the computing system.
Description
Method and System of Displaying a Real-Time Glucose Reading with an
Alarm Clock
The current application is a Patent Cooperation Treaty (PCT) application and claims a priority to a U.S. provisional application serial number 62/478,476 filed on March 29, 2017.
FIELD OF THE INVENTION
The present invention generally relates to a method of displaying a real-time glucose reading with an alarm clock. More specifically, the alarm clock is equipped with a projector that projects a scatter plot showing the history and the future trend of the glucose-level.
BACKGROUND OF THE INVENTION
Conventional glucose monitors use a receiver or a smartphone to display the realtime glucose-level readings. Usually, the numerical value of the real-time glucose-level is displayed on the screen of the receiver or the smartphone. If the glucose-level reaches a dangerously high or dangerously low value, the smartphone or the receiver outputs an alert prompting the user to take corrective action. Dangerously high or dangerously low glucose-level can lead to seizures, brain damage, and is often a very life-threatening situation. Thus, it is imperative that the user is properly notified of the abnormal glucose- level so that corrective actions can be taken. Preferably, the user should take corrective action as soon as the glucose-level starts trending too high or too low.
In most cases however, the receiver or the smartphone is the only means of notifying the user of the real-time glucose-level. This problem is exacerbated when the user goes to sleep, since most users do not go to sleep while carrying their smartphone or
their receiver. Thus, if the user wants to see how the glucose-level is trending, the user must physically reach for the smartphone or the receiver. However, reaching for the receiver or the smartphone while lying on the bed is cumbersome, uncomfortable, and can disturb sleep.
The present invention is a projector alarm clock designed to suit the lives of users suffering from Type 1 and Type 2 diabetes. The alarm clock takes the data from the glucose monitor that the user is wearing and displays this data through the projector on the alarm clock and onto the ceiling or the wall. The alarm clock therefore enables the user to glance quickly at the projection without needing to fumble to their smartphones or their receivers at night. Since the glucose-level is projected onto the wall, anyone walking past the bedroom can also quickly look at the glucose-level. For example, if the user is a child, a parent or caretaker can quickly glance at the wall while the child is sleeping to see the trend of the glucose-level. This provides peace of mind to the parent with minimal disruption for the child.
The alarm clock would also have standard features found in a common bedside alarm clock, such as time, date, temperature, wake alarm, etc. The alarm clock projects the numerical value of the real-time glucose-level and a scatter plot taken over a three- hour time period showing how the glucose-level is trending. This information is projected in large, easy to read graphics on the bedroom wall, ceiling, or floor. The user can thus glance at the projection while lying on the bed without significantly altering his posture. The user can also use the trending information to determine whether or not he or she would soon need to get up to make an insulin correction or consume additional carbohydrates.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a front perspective view of the alarm clock projecting the real-time glucose- level reading and the scatter plot of glucose-level readings onto the wall of the bedroom.
FIG. 2 is a schematic view of the present invention showing the glucose monitor connected to the portable PC device, the remote server, and the microprocessor in the alarm clock.
FIG. 3 is a flow chart showing the order of operation of Step A through Step G.
FIG. 4 is a flow chart showing the sub-processes of Step G, wherein the physically- comfortable electronic band is used to alert the user.
FIG. 5 is a flow chart showing the sub-processes of Step G, wherein the electronic accessory and the electronic socket.
FIG. 6 is a flow chart showing the sub-processes of Step G, wherein the physical display is provided on the alarm clock.
FIG. 7 is a flow chart showing the sub-processes of Step G, wherein the computing system is a microprocessor.
FIG. 8 is a flow chart showing the sub-processes of Step G, wherein the user interface is a plurality of hardwired buttons.
FIG. 9 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device which also outputs the alert when an outlier reading is identified.
FIG. 10 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the portable PC device outputs the alert when an outlier reading is identified. FIG. 11 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the patient profile is linked to at least one related profile.
FIG. 12 is a flow chart showing the sub-processes of Step A, wherein the computing system is a portable PC device communicably coupled to at least one remote server, and wherein the related PC device outputs the alert when an outlier reading is identified.
DETAILED DESCRIPTION OF THE INVENTION
All illustrations of the drawings are for the purpose of describing selected versions of the present invention and are not intended to limit the scope of the present invention.
The present invention is a method and system of displaying a real-time glucose reading with an alarm clock. More specifically, the alarm clock obtains a set of glucose- level readings from a glucose monitor and uses a projector to project the set of glucose- level readings onto the wall or the ceiling of a room. If the glucose-level trends dangerously low or dangerously high, the alarm clock outputs visual and audible alerts notifying the user to take corrective action. The alarm clock also allows the user to preempt an alert by providing a scatter plot showing the trend of the glucose level. The scatter plot shows the history and the future trend of the glucose-level, thereby allowing the user to correct the glucose-level before an alert is activated. In addition to the alarm clock, the present invention also includes alternate minimally invasive alerting device. More specifically, the vibrating bands worn around the arm or legs notify the user of dangerous glucose-levels without disturbing the other occupants of the bed. Similarly, the present invention also allows an existing electronic device to be used as the preferred alerting method.
Referring to FIG. 1 and FIG. 2, the system for the present invention is provided with a computing system, a glucose monitor, and an alarm clock, wherein an acceptable glucose range is stored on the computing system (Step A). The alarm clock is designed as a minimally invasive method of notifying the user of their real-time glucose-level. In the preferred embodiment, the alarm clock is configured to be placed in the bedroom, in clear view of the user who may be laying on the bed. The alarm clock generates an easily visible and easily readable projection of the real-time glucose-level reading onto the wall of the bedroom. The user can thus quickly glance at the projection while lying on the bed, without having to move his or her body, or having to reach for the smartphone or the receiver. In various embodiments of the present invention, the computing system may be integrated into the alarm clock, a mobile computing device, or into a remote server in wireless communication with the alarm clock. The glucose monitor refers to a non- invasive, minimally invasive, or invasive continuous glucose monitor (CGM) that comprises a transmitter and a sensor. The sensor is subcutaneously inserted into the
user's belly, arm, back, or the leg, whereby the sensor reads the glucose-level readings in the surrounding fluids. In one embodiment, the sensor employs an enzyme called glucose oxidase to convert glucose to hydrogen peroxide. The hydrogen peroxide generates an electrical signal which is converted into a glucose-level reading. Several chemical layers applied over the glucose oxidase protect against the fluids inside the user's body that can dilute the glucose oxide.
In the preferred embodiment, the glucose monitor converts the electrical signals to the set of the glucose-level readings. Alternately, the conversion of the electrical signal into a glucose-level may be offloaded to the computing system. Preferably, the set of glucose-level readings comprises a plurality of glucose-level readings taken over a period of time. The time interval between each of the plurality of glucose-level readings is constant. In general, the set of glucose-level readings is recorded in terms of the concentration of glucose in the blood stream. In the preferred embodiment, each glucose- level reading may be measured in milligrams per decalitre (mg/dL). Further, the frequency at which the glucose-level readings are taken may change in other
embodiments.
In most cases, the sensor remains inside the user for several days, continuously measuring the glucose-level. Referring to FIG. 3, the system of the present invention is used to continuously receive the set of glucose-level readings through the glucose monitor (Step B). The set of glucose-level readings is then continuously transmitted to the computing system. More specifically, the transmitter relays the set of glucose-level readings from the glucose monitor to the computing system (Step C). Preferably, the transmitter wirelessly and continuously transmits the set of glucose-level readings to the computing system. The transmitter preferably utilizes a wireless technology standard enabling ultra-high frequency (UHF) radio communication (e.g. Wi-Fi). Preferably, the step of interpreting and analyzing the set of glucose-level readings is off-loaded to the computing system through the wireless transmission. More specifically, the computing system parses through the set of glucose-level readings with the computing system in order to identify at least one outlier reading within the set of glucose-level readings, wherein the outlier reading is outside of the acceptable glucose range (Step D).
The computing system is equipped with a user interface, which allows the user to set the acceptable glucose range and help identify the outlier reading. The outlier reading is a reading from the set of glucose-level readings that is outside the acceptable glucose range. The user sets the acceptable glucose range between a dangerously high and dangerously low glucose-level reading. Thus, if the outlier reading is identified, the glucose-level reading is dangerously high or dangerously low and the user must make an insulin correction immediately. The set of glucose-level readings is relayed from the computing system to the alarm clock (Step E). In addition to identifying the outlier reading, the computing system also archives and stores the historical set of glucose-level readings taken over the lift of the glucose monitor. The set of glucose-level readings may be relayed via an internet connection or a cellular network depending on the type of computing system being utilized.
A projector of the alarm clock displays the set of glucose-level readings (Step F). The projector is mounted to the alarm clock via a swivel bracket which allows the user to point the projector to the walls, ceiling, or the floor of the bedroom. The projector projects the real-time glucose-level reading and a scatter plot showing the change in the glucose-level over time onto the wall. The real-time glucose-level is the numerical value of the glucose-level, measured in mg/dL, displayed in illuminated letters against a black background. Similarly, the scatter plot shows the glucose-level in the Y-axis and the time in the X-axis and may have a line of best fit going through the data points. The scatter plot is illuminated against a black background and is positioned next to the real-time glucose-level reading. Preferably, the scatter plot displays data points taken over a three- hour interval. The time interval of the scatter plot can be increased or decreased via the computing system. The real-time glucose-level reading and the scatter plot preferably fills a substantial portion of the wall, ceiling, or floor, allowing the user to quickly glance at the projection while lying or resting on the bed. The scatter plot and the numerical value is brightly illuminated against a black background. Preferably, the numerical value is positioned adjacent to the scatter plot.
The alarm clock is also designed to output an alert with the alarm clock, if the outlier reading is identified by the computing system (Step G). In the preferred embodiment of the present invention, the outlier reading measures the concentration of
glucose in the bloodstream. Preferably, there is an upper-bound outlier, when the glucose-level is dangerously high, and a lower-bound outlier reading, when the glucose- level is dangerously low. A user interface of the computing system allows the user or another operator of the present invention to change and set the acceptable glucose range. More specifically, the user interface allows the user to input numerical values of the dangerously high and dangerously low glucose-level reading. The numerical value may be the glucose-level concentration measured in mg/dL or any other appropriate unit. For example, the user may enter 130 mg/dL for the upper-bound acceptable glucose range and 70 mg/dL for lower-bound of the acceptable glucose range. Alternately, the acceptable glucose range may change dynamically, according to the programmed rules that take various physical readings into account.
If the set of glucose-level readings crosses the upper-bound outlier reading or the lower-bound outlier reading or falls within the numerical range of the outlier reading, the alarm clock outputs an alert. Preferably, the alarm clock outputs an audible alert that the user can hear without glancing at the alarm clock. The audible alert may be loud enough to disturb the user from sleep. Additionally, the alarm clock may also project visual alerts such as flashing lights, changing colors, and warning messages to notify the user. The user controls the severity and the type of the alerts through the user interface. In addition to alerting the user, the computing system may also send alert messages to the user's close associates. The alert messages may be sent via the internet, cellular networks, or a local area connection.
Referring to FIG. 4, the present invention also relates to providing a non-invasive method of alerting the user by providing a physically-comfortable electronic band, wherein the physically-comfortable electronic band is communicably coupled to the alarm clock. The physically-comfortable electronic band is preferably a wrist band made of soft plastic or fabric that is pleasant to the touch. The physically-comfortable alarm clock is intended to remain on the user for prolonged periods of time and is thus designed to accommodate the user's daily activities. As such, the physically-comfortable electronic band may be waterproof, dustproof, and capable of operating for several days without being recharged. In the preferred implementation, the physically-comfortable electronic band provides a non-invasive way of alerting the user while the user is sleeping. The
physically-comfortable electronic band wirelessly connects to the alarm clock via a UHF radio wave connection. Instead of sounding out a visible or audible alert through the alarm clock and risking waking other occupants of the bedroom, the physically- comfortable electronic band alerts only the user. More specifically, the physically- comfortable electronic band starts vibrating if the outlier reading is identified by the computing system after parsing through the set of glucose-level readings in Step D. In an alternate embodiment of the present invention, the physically-comfortable alarm clock may be wirelessly connected to the computing system directly, via the internet or a cellular network.
Referring to FIG. 5, another non-invasive alerting method involves providing at least one electronic accessory and at least one electronic socket, wherein the electronic socket is operatively connected to the alarm clock, and wherein the electronic accessory is plugged into the electronic socket. In the preferred implementation, the electronic socket selectively allows the flow of electricity from an existing power outlet to the electronic device. As such, the electronic socket powers the electronic accessory if the outlier reading is identified by the computing system in Step D. More specifically, when the computing system identifies the outlier reading, the alarm clock signals the electronic socket to allow the flow of electricity from the power outlet to the electronic device. The signal is preferably sent through a wireless connection between the alarm clock and the electronic socket. The preferred embodiment of the electronic socket has a plug end that connects to an existing wall-mounted power outlet. Similarly, the electronic accessory also has a plug end that is adapted to connect into the electronic socket. The electronic accessory refers to an existing electronic device that a user can choose to alert themselves. For example, the electronic accessory may be a Fan set to high, or a radio with the volume turned up. In one possible embodiment, the electronic accessory may be an alerting light. As such, when the outlier reading is identified, the electronic socket allows the flow of electricity from the power outlet to the alerting light, thereby activating the alerting light. In one embodiment of the present invention, the alert from the electronic device substitutes the alert from the alarm clock. In another embodiment, both the electronic device and the alarm clock may both alert the user.
Referring to FIG. 6, in addition to providing an audible or visible alert via the projector, a physical display is provided, wherein the electronic display is operatively integrated into the alarm clock. The preferred embodiment of the alarm clock is a rectangular prism with slanted sidewall, with the physical display integrated into one of the slanted sidewalls. The physical display displays the set of glucose-level readings during Step F. Preferably, the physical display is a liquid crystal display (LCD) or light emitting diode (LED) screen that displays the time, the scatter plot, and the numerical value of the real-time glucose-level.
Referring to FIG. 7 and FIG. 8, in the preferred embodiment of the present invention, the computing system is contained within the alarm clock itself. As such, a microprocessor is provided as the computing system, wherein the microprocessor is operatively integrated into the alarm clock. The microprocessor is programmed to interpret the set of glucose-level readings transmitted from the glucose monitor and control the alarm clock accordingly. As such, the set of glucose-level readings is directly communicated from the glucose monitor to the alarm clock. Preferably, the set of glucose-level readings is communicated over a UHF radio wave connection between the glucose monitor and the microprocessor. In this preferred embodiment, the user interface is provided as a plurality of hardwired buttons, wherein each hardwired button is operatively integrated into the alarm clock and is associated to a corresponding setting adjustment for the alarm clock. The microprocessor is programmed to detect the activation of a specific button, wherein the specific button is from the plurality of hardwired buttons. The microprocessor then executes the corresponding setting adjustment for the specific button. The corresponding setting adjustment refers to various settings of the alarm clock such as the UHF radio wave connection between the glucose monitor and the alarm clock, the outlier reading value, the range of outlier readings, and the connection between the alarm clock, the electronic socket, the electronic accessory, and the physically-comfortable electronic band. In an alternate embodiment of the present invention, an application that runs on a smartphone may be used to adjust the settings of the alarm clock. The application may wirelessly communicate with the microprocessor via a UHF radio wave, a Wi-Fi, or a cellular network to communicate the desired adjustments to the settings of the alarm clock.
Referring to FIG. 9, in an alternate embodiment of the present invention, the computing system may be contained in the smartphone itself. More generically, a portable personal computing (PC) device is the computing system, wherein the portable PC is communicably coupled to the alarm clock. The portable PC device can be, but is not limited to, a smartphone, a laptop, a tablet, or similar client computing devices. The portable PC device runs an application allowing the portable PC device to connect to the glucose monitor and relay the set of glucose-level readings to the alarm clock.
Accordingly, the set of glucose readings is indirectly communicated from the glucose monitor, through the portable PC device, and to the alarm clock. Preferably, the glucose monitor uses UHF radio wave to connect to the portable PC device, whereas the portable PC device may use Wi-Fi, a cellular network, or a similar wireless communication standard to connect to the alarm clock. In this embodiment, the user interface is integrated into the application. The user interface allows the user to adjust the settings of both the glucose monitor and the alarm clock. Further, the application also prompts the user to view the set of glucose-level readings through the portable PC device. Preferably, the set of glucose-level readings is displayed with the portable PC device, only if the portable PC device confirms to view the set of the glucose-level readings. Once confirmed, the application displays the numerical values of the set of glucose-level readings along with the accompanying continuous line graph on the screen of the portable PC device itself. If the outlier reading is identified during Step D, the portable PC device activates the alarm clock which outputs the alert. Additionally, the application is also capable of outputting the alert with the portable PC device, if the outlier reading is identified by the computing system. The portable PC device may output both a visible alert and an audible alert simultaneously.
Referring to FIG. 10, in yet another embodiment of the present invention, the portable PC device is connected to at least one remote server, wherein the portable PC device is communicably coupled to the remote server, and wherein the remote server is communicably coupled to the alarm clock. More specifically, the portable PC device and the at least one remote server are used to enable a cloud computing platform. Preferably, the cloud computing platform comprises a network of servers communicating with a plurality of portable PC devices over the internet. The network of servers stores, manages
and processes, large datasets of glucose-level readings generated by the plurality of portable PC devices. In the preferred embodiment, the portable PC device is connected to the remote server over a wireless local area network (WLAN). As such, the portable PC device relays the set of glucose-level readings from the glucose monitor to the remote server. The remote server is used to manage a patient profile. The patient profile transmits the real-time glucose-level readings to the alarm clock and archives glucose- level readings taken over the life of the glucose-monitor. Additionally, the patient profile also may also contain the user's medical history. The set of glucose readings from the glucose monitor is indirectly communicated from the glucose monitor, through the portable PC device, through the remote server, and to the alarm clock. To achieve this, the alarm clock is connected to remote server over the WLAN. Preferably, the portable PC device offloads the storage and the processing of the set of glucose-level readings to the remote server. As such, the set of glucose-level readings is stored on the remote server as part of the patient profile.
The user can access the set of glucose-level readings via an application that runs on the portable PC device. The application prompts the user to view the set of glucose - level readings through the portable PC device. If the user confirms to view the set of glucose-level readings, the set of glucose-level readings is displayed with the portable PC device. The set of glucose-level readings is displayed on the screen of the portable PC device as a continuous line graph or a scatter plot with a line of best fit going through the data points. The numerical value of the real-time glucose-level concentration is also displayed. The application also allows the user to set or change the acceptable glucose range which identifies the outlier reading. If the outlier reading is identified by the computing system in Step D, the portable PC device outputs the alert. Since the computing system is distributed between the portable PC device and the remote server, either the portable PC device or the remote server may identify the outlier reading.
Referring to FIG. 11 and FIG. 12, the cloud computing platform may also allow the user to share the set of glucose-level readings with one or more associates. Associates refers to the user's friends and family members. To access the set of glucose-level readings, the associate must open at least one related profile which is managed by the remote server. The related profile is linked to the patient profile and is associated to a
related PC device. The related PC device is used by the associate to communicate with the remote server. Unlike the patient profile, the related profile includes only the minimal amount of personal information about the associate.
Preferably, the related profile is granted the same privileges as the patient profile, and the associate can view the user's set of glucose-level readings stored in the computing system. The associate controls the associate profile through an application running on the related PC device. The application may prompt to view the set of glucose- level readings through the related PC device. If the related PC device confirms to view the set of glucose-level readings, the set of glucose-level readings is displayed on the related PC device. The set of glucose-level readings may be displayed as a continuous line graph, a scatter plot, or a numerical value of the real-time glucose-level reading. Further, the application also outputs an alert with the related PC device, if the outlier reading is identified by the computing system in Step D. The alert may be visual or audible alert that overrides any application that is currently running on the related PC device. For example, the related PC device may output an audible alarm and flashing lights to alert the associate.
Although the invention has been explained in relation to its preferred
embodiment, it is to be understood that many other possible modifications and variations can be made without departing from the spirit and scope of the invention as hereinafter claimed.
Claims
1. A method of displaying a real-time glucose reading with an alarm clock, the method comprises the steps of:
(A) providing a computing system, a glucose monitor, and an alarm clock, wherein an acceptable glucose range is stored on the computing system;
(B) continuously receiving a set of glucose-level readings through the glucose monitor;
(C) relaying the set of glucose-level readings from the glucose monitor to the computing system;
(D) parsing through the set of glucose-level readings with the computing system in order to identify at least one outlier reading within the set of glucose-level readings, wherein the outlier reading is outside of the acceptable glucose range;
(E) relaying the set of glucose-level readings from the computing system to the alarm clock;
(F) displaying the set of glucose-level readings with a projector of the alarm clock; and
(G) outputting an alert with the alarm clock, if the outlier reading is
identified by the computing system in step (D).
2. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing a physically-comfortable electronic band, wherein the physically-comfortable electronic band is communicably coupled to the alarm clock; and
vibrating the physically-comfortable electronic band, if the outlier reading is identified by the computing system in step (D).
3. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing at least one electronic accessory and at least one electronic socket, wherein the electronic socket is operatively connected to the alarm clock, and wherein the electronic accessory is plugged into the electronic socket; and activating the electronic accessory by powering the electronic socket, if the outlier reading is identified by the computing system in step (D).
4. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing a physical display, wherein the electronic display is operatively integrated into the alarm clock; and
displaying the set of glucose-level readings with the physical display during step (F).
5. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing a microprocessor as the computing system, wherein the microprocessor is operatively integrated into the alarm clock; and
directly communicating the set of glucose-level readings from the glucose monitor to the alarm clock.
6. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 5 comprises the steps of:
providing a plurality of hardwired buttons, wherein each hardwired button is operatively integrated into the alarm clock and is associated to a corresponding setting adjustment for the alarm clock;
detecting activation of a specific button with the microprocessor, wherein the specific button is from the plurality of hardwired buttons; and
executing the corresponding setting adjustment for the specific button with the microprocessor.
7. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing a portable personal computing (PC) device as the computing system, wherein the portable PC device is communicably coupled to the alarm clock; and
indirectly communicating the set of glucose-level readings from the glucose monitor, through the portable PC device, and to the alarm clock.
8. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 7 comprises the steps of:
prompting to view the set of glucose-level readings through the portable PC device; and
displaying the set of glucose-level readings with the portable PC device, if the portable PC device confirms to view the set of glucose-level readings.
9. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 7 comprises the steps of:
outputting the alert with the portable PC device, if the outlier reading is identified by the computing system in step (D).
10. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 1 comprises the steps of:
providing a portable personal computing (PC) device and at least one remote server as the computing system, wherein the portable PC device is communicably coupled to the remote server, and wherein the remote server is communicably coupled to the alarm clock;
providing a patient profile managed by the remote server;
indirectly communicating the set of glucose-level readings from the glucose monitor, through the portable PC device, through the remote server, and to the alarm clock; and
storing the set of glucose-level readings as a part of the patient profile with the remote server.
11. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 10 comprises the steps of:
prompting to view the set of glucose-level readings through the portable PC device; and
displaying the set of glucose-level readings with the portable PC device, if the portable PC device confirms to view the set of glucose-level readings.
12. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 10 comprises the steps of:
outputting the alert with the portable PC device, if the outlier reading is identified by the computing system in step (D).
13. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 10 comprises the steps of:
providing at least one related profile managed by the remote server, wherein the related profile is linked to the patient profile and is associated to a related PC device;
prompting to view the set of glucose-level readings through the related PC device; and
displaying the set of glucose-level readings with the related PC device, if the related PC device confirms to view the set of glucose-level readings.
14. The method of displaying a real-time glucose reading with an alarm clock, the method as claimed in claim 10 comprises the steps of:
providing at least one related profile managed by the remote server, wherein the related profile is linked to the patient profile and is associated to a related PC device; and
outputting the alert with the related PC device, if the outlier reading is identified by the computing system in step (D).
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US201762478476P | 2017-03-29 | 2017-03-29 | |
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