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WO2018155219A1 - Système de remplissage aseptique et procédé de remplissage aseptique - Google Patents

Système de remplissage aseptique et procédé de remplissage aseptique Download PDF

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Publication number
WO2018155219A1
WO2018155219A1 PCT/JP2018/004517 JP2018004517W WO2018155219A1 WO 2018155219 A1 WO2018155219 A1 WO 2018155219A1 JP 2018004517 W JP2018004517 W JP 2018004517W WO 2018155219 A1 WO2018155219 A1 WO 2018155219A1
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WO
WIPO (PCT)
Prior art keywords
container
gas
blowing
aseptic
unit
Prior art date
Application number
PCT/JP2018/004517
Other languages
English (en)
Japanese (ja)
Inventor
佐々木　哲也
利明 諏訪
貢 大頭
岩下　健
Original Assignee
東洋製罐株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 東洋製罐株式会社 filed Critical 東洋製罐株式会社
Publication of WO2018155219A1 publication Critical patent/WO2018155219A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/46—Component parts, details or accessories; Auxiliary operations characterised by using particular environment or blow fluids other than air
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/4273—Auxiliary operations after the blow-moulding operation not otherwise provided for
    • B29C49/42808—Filling the article
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/02—Machines characterised by the incorporation of means for making the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00—Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations

Definitions

  • the present invention relates to an aseptic filling system and an aseptic filling method for filling a sterilized content liquid in a sterilized container in an aseptic environment, and in particular, an in-line blow type that performs consistently from container molding to filling and sealing of the content liquid.
  • the present invention relates to an aseptic filling system and an aseptic filling method.
  • a sterilizing agent such as hydrogen peroxide is injected into the container.
  • a preform such as hydrogen peroxide is sprayed onto the preform which is a preform of the container to sterilize the preform (see Patent Document 1). Is known).
  • the container When the container is sterilized using a disinfectant such as hydrogen peroxide, it is necessary to reduce the concentration of the disinfectant in the container to a specified value or less by the time the container is filled with the contents. Therefore, when the container is sterilized in the container conveyance path provided on the upstream side of the filling unit, the sterilizing agent is removed by removing the sterilizing agent into the container conveyance path by blowing out sterile air into the container.
  • Equipment needs to be installed. And when such a disinfectant removal equipment is installed, not only will the apparatus configuration become complicated and the apparatus cost will increase, but the distance of the container transport path will become longer, and downsizing of the entire aseptic filling system will be hindered. There was a problem of being.
  • An object of the present invention is to provide an aseptic filling system and an aseptic filling method that realizes cost reduction and downsizing of the entire system.
  • An aseptic filling system is an aseptic filling system for filling a sterilized container with a sterilized content liquid in an aseptic environment, a container forming unit having a blow molded turret, and a downstream side of the container forming unit.
  • a machine is installed on the upstream side of the container release point of the blow-molded turret so as to apply a sterilizing agent to the container or preform, and is disposed along the container transport path in the container transport path,
  • An aseptic holding machine having a gas blowing surface for blowing out aseptic gas toward the mouth of the container to be conveyed along the conveying path is installed.
  • Ri is intended to solve the above problems.
  • the aseptic filling method of the present invention is an aseptic filling method in which a sterilized container is filled with a sterilized content liquid in an aseptic environment, and before the blow molded turret releases the container, the container or the plug is sterilized by a sterilization processor.
  • a sterilizing agent is applied to the renovation, and in the container conveyance path between the blow-molded turret and the filling unit, the container conveyance path is conveyed by an aseptic holding machine having a gas blowing surface arranged along the container conveyance path.
  • the above-mentioned problem is solved by blowing out aseptic gas toward the mouth of the container.
  • the aseptic gas blown out from the aseptic holder suppresses the intrusion of dust or the like into the container in the container transport path, and maintains the inside of the container in a sterile state.
  • the following effects can be obtained.
  • the mouth of the container and the inside of the container can be locally maintained in a sterile state by the aseptic holder without maintaining the entire container transfer path in a sterile state, the entire container transfer path is maintained in a sterile chamber.
  • the degree of freedom in designing the surrounding environment of the container conveyance path can be improved.
  • the gas blowing surface is disposed at a position where the distance from the mouth of the container transported through the container transport path is 1 mm or more and less than 30 mm. Even when a container is transported at a high speed of up to 2.0 m / s or the like, it is possible to avoid interference between the blowing part of the aseptic holder and the container, and the blown out sterile gas entrains outside air. Since aseptic gas can reach the mouth, contamination of the mouth of the container and the container can be avoided reliably.
  • the aseptic gas blowing speed by the aseptic holder is set to 1.0 to 3.0 times the container conveying speed by the container conveying machine, 0.4 to Even when the container is transported at a high speed of 2.0 m / s or the like, it is possible to allow the sterile gas to reach the mouth of the container while avoiding the blown out sterile gas from entraining outside air. , Contamination of the container can be reliably avoided.
  • the opening ratio of the gas blowing surface is set to 40% or more, it is possible to blow out aseptic gas with a sufficient air volume evenly from the entire surface of the gas blowing surface. Therefore, contamination of the container can be avoided well.
  • the intermediate adjustment member is interposed in the flow path between the supply pipe connection portion and the gas blowing surface of the case, and is at an intermediate position between the supply pipe connection portion and the gas blowing surface. Even if the size of the blowing part in the container transport direction is set to be long, the flow of aseptic gas in the case is adjusted and the aseptic gas is blown out uniformly from the entire surface of the gas blowing surface. be able to.
  • the supply pipe connecting portion is formed at a plurality of positions other than both ends in the container transport direction of the case at intervals, so that the size of the blowing portion in the container transport direction can be reduced.
  • the aseptic holding machine includes a plurality of blowing sections arranged side by side along the container transport direction, so that the container transport speed in each section of the container transport path can be increased. Since the aseptic gas blowing speed can be adjusted, the aseptic gas can be satisfactorily delivered to the mouth of the container even when the container conveying speed of each section of the container conveying path is different.
  • the apparatus sterilization mechanism includes the sterilization gas supply unit connected to the sterile gas supply pipe between the gas supply unit and the sterilization filter, and the exhaust blower connected to the blowing unit.
  • the apparatus sterilization mechanism has the cover member that is detachably attached to the blowing section so as to cover the gas blowing surface, thereby operating the apparatus sterilization mechanism of the aseptic holder. When this is done, it is possible to reliably prevent the sterilizing gas from leaking out from the gas blowing surface and attaching the sterilizing gas to the peripheral equipment of the container conveyance path.
  • Explanatory drawing which shows the whole outline
  • Explanatory drawing which shows the blowing part vicinity of an aseptic holding
  • Explanatory drawing which shows the structure of an aseptic holding
  • the graph which shows the change of the container conveyance speed in a container conveyance path.
  • Explanatory drawing which shows the conditions of a 1st experiment example.
  • surface which shows the conditions and result of a 2nd experiment example.
  • Explanatory drawing which shows the conditions and result of a 3rd experiment example.
  • the aseptic filling system 10 aseptically fills a sterilized container C with a sterilized content liquid.
  • a container molding unit 20 having a blow molded turret 23, and a container molding unit. 20, a filling unit 30 disposed on the downstream side, a sterilization treatment machine 40 for sterilizing a preform (not shown) which is a preform of the container C, and a container between the blow-molded turret 23 and the filling unit 30.
  • a container transport machine 50 installed in the transport path 25 and an aseptic holder 60 installed in the container transport path 25 are provided.
  • the container forming unit 20 includes an inlet portion 21 into which a preform is charged, a heating portion 22 that is disposed downstream of the inlet portion 21 and heats the preform, and a downstream side of the heating portion 22.
  • the container transport path 25 is provided.
  • the filling unit 30 includes an inlet portion 31 connected to the outlet portion 24 of the container forming unit 20, and a plurality of turrets arranged on the downstream side of the inlet portion 31 to transport the container C.
  • a capping part 34 and an outlet part 35 for carrying out a container C mounted with a cap disposed on the downstream side of the capping part 34 are provided.
  • Each process in the filling unit 30 is performed in a sterile chamber maintained in a sterile state.
  • aseptic air is introduced from the outside in the vicinity of the filling portion 33, and the aseptic air is collected (exhausted) in the vicinity of the inlet portion 31 and the outlet portion 35, whereby the inside of the sterile chamber is kept at a positive pressure.
  • the sterilization processor 40 is installed between the inlet 21 and the heating unit 22 of the container forming unit 20, and has a sterilizing agent (hydrogen peroxide in the present embodiment) on the inner and outer surfaces of the preform. ) Is blown out to sterilize the preform.
  • a sterilizing agent hydrogen peroxide in the present embodiment
  • the container transporter 50 includes a plurality (two in this embodiment) of transport turrets 51. These transport turrets 51 are provided with a plurality of grippers 52 that grip the neck of the container C as shown in FIG.
  • the container transporter 50 is configured to gripper transport the container C with the mouth side of the container C facing upward.
  • the container C may be transported by turret transport instead of gripper transport.
  • the sterilization holder 60 is provided with aseptic gas (in this embodiment, from a gas blowing surface 60a directed downward with respect to the container C conveyed through the container conveyance path 25 by the container conveyance device 50. Aseptic air) is blown out to prevent dust or the like from entering the container C or adhering to the mouth of the container C.
  • aseptic gas in this embodiment, from a gas blowing surface 60a directed downward with respect to the container C conveyed through the container conveyance path 25 by the container conveyance device 50.
  • Aseptic air is blown out to prevent dust or the like from entering the container C or adhering to the mouth of the container C.
  • the aseptic holder 60 includes an aseptic gas blowing mechanism for blowing out aseptic gas to the container C and an apparatus sterilizing mechanism for sterilizing the circuit of the aseptic gas blowing mechanism.
  • the aseptic gas blowing mechanism of the aseptic holder 60 includes a gas supply unit 61 for supplying gas, a sterilization filter 65 for gas, a distributor 64 for distributing sterilized gas, and a distributor.
  • the gas supply unit 61 and the sterilization filter 65, the sterilization filter 65 and the distributor 64, the distributor 64, and the blowing unit 62 are connected by gas supply pipes 63 (63a, 63b, 63c), respectively.
  • the gas supplied from the gas supply unit 61 is sterilized after passing through the sterilization filter 65, distributed by the distributor 64, and supplied to each blowing unit 62 via the gas supply pipe 63c.
  • a plurality (three) of the above-described blowing portions 62 are provided. Specifically, as shown in FIG. 1, the blow-molded turret 23 and the upstream-side transport turret in the container transport path 25.
  • the first blowing section 62A is installed in the connection section between the first and second sections 51. Subsequently, the second blowing section 62B is installed in the center of the transport section by the transport turret 51.
  • a third blowing section 62 ⁇ / b> C is installed in the conveyance section by the turret 51.
  • FIG. 3 schematically shows the aseptic holder 60, and in FIG. 3, it is illustrated as having two blowing portions 62.
  • each blowing section 62 is formed with a curved overall shape corresponding to each arc-shaped transport area by the upstream and downstream transport turrets 51.
  • a plurality of blowing portions 62 are provided over the entire region (or almost the entire region) of the container conveyance path 25 installed between the blow-molded turret 23 and the filling unit 30. However, they are installed side by side along the container conveying direction.
  • the container conveyance speed in each section of the container conveyance path 25 (the blowing sections 62A, 62B, 62C and the connection sections of the respective sections, the conveyance section) is different from each other. Since the aseptic gas blowing speed from the blowing section 62 is preferably set to 1.0 to 3.0 times the container transport speed, each section (the blowing sections 62A, 62B, 62C and the connecting sections of the sections, It is preferable to set the blowing speed of the sterilized gas from each blowing section 62 according to the container conveying speed in the conveying section).
  • a method for varying the sterilizing gas blowing speed in each part of each blowing part 62 a plurality of gas supply parts 61 and a sterilization filter 65 are prepared, and different gas supply parts 61 are connected to each blowing part 62.
  • the common gas supply unit 61 and the sterilization filter 65 are connected to each blowing unit 62, it is conceivable to change the speed of aseptic gas sent to each blowing unit 62 by the distributor 64.
  • the sterilized gas blowing speed from each blowing section 62 may be set to be the same.
  • each blowing section 62 is as follows.
  • each blowing section 62 has a case 62a, a blowing face forming member 62b, and an intermediate adjusting member 62c as shown in FIG.
  • the case 62a has a sterile gas supply pipe connection portion formed on the upper surface thereof to which the gas supply pipe 63c is connected, and a lower opening portion opened on the lower surface side facing the container transport path 25 side. have.
  • portions other than the supply pipe connecting portion and the lower opening portion are not opened and are closed.
  • the blow-out surface forming member 62b is configured as a plate-like member (a punching metal in the present embodiment) having a plurality of through holes, and is attached to the lower opening of the case 62a.
  • the blowing surface forming member 62b forms a gas blowing surface 60a for blowing out aseptic gas.
  • the width dimension (dimension in the direction orthogonal to the container conveying direction) of the gas blowing surface 60a (blowing surface forming member 62b) is set wider than the diameter of the container C, and is 135% to 160% of the diameter of the container C (38 mm diameter). In this case, it is preferable to design with about 51 mm to 60 mm).
  • the gas blowing surface 60a When the width dimension of the gas blowing surface 60a is smaller than 135% with respect to the diameter of the container C, the gas blowing surface 60a is likely to come into contact with the mouth portion of the container C and may hinder transportation, and when the width dimension is larger than 160% It becomes difficult to minimize the installation space for the machine 50.
  • the container C is conveyed along the center in the width direction of the gas blowing surface 60a.
  • the intermediate adjustment member 62 c is configured as a plate-like member (a punching metal in the present embodiment) having a plurality of through holes, and a supply pipe connecting portion formed on the upper surface of the case 62 a; Between the gas blowing surface 60a (blowing surface forming member 62b), it is attached inside the case 62a.
  • the intermediate adjustment member 62c is disposed so as to intersect (orthogonally) the aseptic gas flow path between the gas supply pipe 63 and the gas blowing surface 60a.
  • an intermediate adjusting member 62c is installed at the center position between the supply pipe connecting portion and the gas blowing surface 60a.
  • each blowing section 62 configured in this manner, the sterilized gas supplied into the case 62a through the gas supply pipe 63c and the sterilization filter 65 connected to the supply pipe connection section of the case 62a is supplied to the intermediate adjustment member 62c and the blowing section. The gas is blown out from the gas blowing surface 60a through the surface forming member 62b.
  • the device sterilization mechanism of the aseptic holding machine 60 is contaminated with dust or the like in the circuit of the sterile gas blowing mechanism when the positive pressure holding such as completely stopping the operation of the aseptic filling system 10 is released.
  • the circuit of the aseptic gas blowing mechanism is sterilized in order to prevent the contaminated gas from being blown out from the blowing unit 62.
  • the sterilization mechanism of the aseptic holder 60 includes a sterilization gas supply unit 66 connected to the gas supply pipe 63 between the gas supply unit 61 and the sterilization filter 65, a sterilization gas supply unit 66, and A supply valve 66a disposed between the gas supply pipes 63, an exhaust blower 68 connected to each blowing section 62 by an exhaust pipe 67, a recovery valve 68a disposed between the blowing section 62 and the exhaust blower 68, It is comprised from the cover member 69 attached to each blowing part 62 so that attachment or detachment is possible so that the gas blowing surface 60a may be covered.
  • the sterilizing gas supply unit 66 may be shared with the cap sterilizing gas supply unit.
  • the device sterilization procedure of the circuit of the sterile gas blowing mechanism using the device sterilization mechanism of the aseptic holder 60 is as follows.
  • the recovery valve 68a is opened, and the exhaust blower 68 is turned on manually.
  • a common cover member 69 is attached to the blowing part 62 so as to cover the gas blowing surface 60 a of each blowing part 62.
  • a plurality of cover members 69 may be prepared, and the cover members 69 may be individually attached to the respective blowing portions 62.
  • the supply valve 66a is opened, and sterilization gas (hydrogen peroxide gas in this embodiment) is supplied from the sterilization gas supply unit 66 to the gas supply pipe 63a.
  • each part (blow-out part 62, gas supply pipe 63a, 63b, 63c, distributor 64, sterilization filter 65, etc.) which comprises the circuit of an aseptic gas blowing mechanism is sterilized with the supplied sterilization gas.
  • the cover member 69 prevents the sterilizing gas from being blown out to the outside of the blowing unit 62, so that the sterilizing gas can be prevented from adhering to the surrounding environment of the aseptic holder 60.
  • the supply valve 66 a is closed, the supply of the sterilizing gas from the sterilizing gas supply unit 66 is stopped, and then the cover member 69 is removed from the blowing unit 62.
  • the recovery valve 68a is closed and the exhaust blower 68 is turned off manually. The removal of the cover member 69 and the procedure for turning off the exhaust blower 68 may be reversed.
  • Aseptic gas blowing speed V1 ⁇ 25.0m / s
  • Blowing surface forming member 62b punching metal ( ⁇ 6 ⁇ 8p staggered, opening ratio 51%)
  • State of fine particles in test apparatus 100,000 to 400,000 particles of 0.5 ⁇ m or more / ft 3
  • the distance CL between the gas blowing surface 60a and the mouth of the container C is preferably set to 1 mm or more and less than 30 mm, more preferably 10 mm or more and 20 mm or less. It was. That is, as shown in the table of FIG. 6, when the interval CL is set to 30 mm, a relatively large blowing speed V1 (10 m / s or more, 18.0 m / s, 18.0 m / s or more, 25.0 m / s For the first time at 25.0 m / s or more, the number of particles in the container C became zero, or the number of particles in the container C did not become zero.
  • the distance CL between the gas blowing surface 60a and the mouth of the container C is preferably set to 1 mm or more in order to avoid interference between the gas blowing surface 60a and the mouth of the container C.
  • the blowout surface forming member 62b is made of punching metal, it is preferable to set the aperture ratio to 63% or less in consideration of the rigidity of the blowout surface forming member 62b.
  • the gas supply pipe The aseptic gas supplied from 63 is not evenly blown out from the gas blowing surface 60a, in other words, there is a possibility that unevenness occurs in the blowing speed of the sterile gas blown out from the gas blowing surface 60a. Therefore, in this experimental example, as shown in FIG.
  • the connection position of the gas supply pipe 63 in the container transport direction, the number of the gas supply pipes 63 connected to the blowing section 62, the installation conditions and the opening of the intermediate adjustment member 62c The rate of sterilized gas blowing from the gas blowing surface 60a was confirmed by changing the rate.
  • the measurement positions of the blown wind speed are a plurality of arrows in the drawing of FIG. 8 are the positions of both ends of the blowing section 62, the C position is the center position of the blowing section 62, and the A, B, C, D, and E positions are equally spaced in the container transport direction. (See the drawing of FIG. 8).
  • condition 3 the supply port is tested in four patterns of B / D position, B / C position, A / C position, and A / D position, and in condition 4, it is tested in one pattern of A / C / E position. Went. Further, when the intermediate adjustment member 62C is not installed between the connection position of the gas supply pipe 63 and the blowing surface 62b (length: 80 mm) (denoted as “none” in the table of FIG. 8), the intermediate adjustment member is installed.
  • the gas supply pipe is connected to the blowing part 62 at a plurality of locations that are evenly separated in the container conveying direction, excluding both end positions in the container conveying direction. It has been found preferable to connect 63.
  • the gas supply speed (supply amount) may be changed for each gas supply pipe 63 according to the container conveyance speed.
  • the gas supply pipe 63 is connected to the blowing portion 62 at three positions, that is, both end positions (A position and E position) in the container transport direction and a central position (C position) in the container transport direction. Even when connected, there was a large difference between the maximum wind speed and the minimum wind speed, and the wind speed variation was 137% to 81%. Note that the maximum wind speed was measured at a position immediately below both end positions (A position, E position). On the other hand, when the supply port is installed at two locations of the B / D position, the B / C position, the A / C position, and the A / D position as in the condition 3, from the conditions 1, 2, and 4 However, the range of wind speed variation tended to narrow.
  • the best pattern is the gas supply to the blowing section 62 at a plurality of locations (B position, D position) equally spaced in the container transport direction, excluding both end positions in the container transport direction.
  • the pipe 63 was connected, and the wind speed variation was 118% to 79%, and the difference between the maximum wind speed and the minimum wind speed could be kept small.
  • the intermediate adjusting member 62c in order to blow out aseptic gas evenly from the gas blowing surface 60a, it is preferable to install the intermediate adjusting member 62c at an intermediate position between the supply pipe connecting portion and the blowing surface forming member 62b.
  • the installation position of the intermediate adjustment member 62c in the vertical direction is a central position between the supply pipe connection portion and the blowing surface forming member 62b, rather than the position closer to the supply pipe connection portion or the position closer to the intermediate adjustment member 62c. It has also been found preferable.
  • the container transporter 50 has been described as being configured of a plurality of transport turrets 51.
  • the specific mode of the container transporter 50 is as long as the container C can be transported.
  • the container transporter 50 may be configured from a conveyor or the like that transports the container C linearly.
  • the container C is transported in the upward state by the container transport machine 50.
  • the transport posture of the container C by the container transport machine 50 is not limited to the above.
  • the container C The container C may be transported in a downward state with its mouth facing downward.
  • it has been described that the container C is transported in an upward state in all the steps.
  • the transport posture of the container C may be arbitrarily designed according to the embodiment.
  • the sterilization holder 60 blows the sterilized gas downward, but any sterilization gas may be blown out toward the mouth of the container C as long as it is blown out.
  • any sterilization gas may be blown out toward the mouth of the container C as long as it is blown out.
  • aseptic gas may be blown upward.
  • the gas blowing surface 60a is formed by the blowing surface forming member 62b provided separately from the case 62a.
  • the gas blowing surface 60a may be provided integrally with the case 62a. Good.
  • the blow-out surface forming member 62b is described as being configured as a punching metal.
  • the specific form of the blow-out surface forming member 62b includes a plurality of blow-out holes and a gas blow-out surface. Any material can be used as long as sterile gas can be blown out uniformly from the entire surface of 60a.
  • the blowing surface forming member 62b may be configured as a net-like member made of metal, synthetic resin, or the like.
  • the intermediate adjustment member 62c has been described as being configured as a punching metal.
  • the intermediate adjustment member 62c is described with respect to the supply pipe connection portion of the case 62a and the gas blowout. Any member may be used as long as it is disposed at an intermediate position with respect to the surface 60a and can blow out aseptic gas evenly from the entire surface of the gas blowing surface 60a. You may comprise as a net-like member which consists of.
  • the blowing unit 62 gas blowing surface 60a
  • the blowing unit 62 is described as being installed over the entire area (or almost the entire area) of the container conveyance path 25. However, dust in the container conveyance path 25 is mixed.
  • the blowing unit 62 may be installed only in a part of the region where it is easy to install, or the blowing unit 62 may be installed in a position other than the container conveyance path 25 (for example, a container conveyance region by the blow molding turret 23).
  • each part of the filling unit 30 has been described as being covered with one aseptic chamber. You may comprise so that it may cover with a chamber.
  • the sterilization processor 40 is described as being configured to sterilize the preform between the inlet portion 21 and the heating unit 22 of the container forming unit 20.
  • the specific configuration of the machine 40 is not limited to the above, as long as it is installed so as to apply a bactericidal agent on the upstream side of the container release point RP (see FIG. 1) of the blow-molded turret 23 and perform a bactericidal treatment.
  • the gas is contained in the container forming unit 20 and contains the sterilizing agent.
  • the sterilizing agent may be blown off by blowing high-pressure air to the container C immediately after the blow molding at the last part of the blow molded turret 23.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Basic Packing Technique (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)

Abstract

L'invention concerne un système de remplissage aseptique et un procédé de remplissage aseptique, permettant d'obtenir une simplification de la configuration de l'appareil, une réduction du coût de l'appareil et une miniaturisation du système dans son ensemble, tout en améliorant le maintien d'un état aseptique d'un récipient, en plus de garantir la liberté de conception de l'environnement autour d'un trajet de transport de récipient. Un système de remplissage aseptique (10) qui remplit un récipient stérilisé avec des contenus liquides stérilisés dans un environnement aseptique comprend : une machine de traitement de stérilisation (40) disposée de manière à souffler un agent de stérilisation sur un récipient (C) ou une préforme sur le côté amont d'un point de libération de récipient (RP) d'une tourelle de moulage par soufflage (23) ; et, dans un trajet de transport de récipient (25), une machine de conservation aseptique (60) qui est agencée le long du trajet de transport de récipient (25) et qui présente une surface de soufflage de gaz (60a) destinée à souffler un gaz aseptique vers une partie d'embouchure du récipient (C) qui est transporté sur le trajet de transport de récipient (25).
PCT/JP2018/004517 2017-02-22 2018-02-09 Système de remplissage aseptique et procédé de remplissage aseptique WO2018155219A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017030720A JP6859740B2 (ja) 2017-02-22 2017-02-22 無菌充填システムおよび無菌充填方法
JP2017-030720 2017-02-22

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CN114772535A (zh) * 2022-06-01 2022-07-22 华夏生生药业(北京)有限公司 一种葡萄糖酸钙注射液制备的灌封装置

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