+

WO2018153556A1 - Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers - Google Patents

Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers Download PDF

Info

Publication number
WO2018153556A1
WO2018153556A1 PCT/EP2018/050269 EP2018050269W WO2018153556A1 WO 2018153556 A1 WO2018153556 A1 WO 2018153556A1 EP 2018050269 W EP2018050269 W EP 2018050269W WO 2018153556 A1 WO2018153556 A1 WO 2018153556A1
Authority
WO
WIPO (PCT)
Prior art keywords
stearate
coated
preparations
pigments
group
Prior art date
Application number
PCT/EP2018/050269
Other languages
German (de)
French (fr)
Inventor
Delphine CHANTY
Thomas Raschke
Original Assignee
Beiersdorf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf Ag filed Critical Beiersdorf Ag
Priority to EP18700101.1A priority Critical patent/EP3585353A1/en
Publication of WO2018153556A1 publication Critical patent/WO2018153556A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/621—Coated by inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/651—The particulate/core comprising inorganic material

Definitions

  • the invention relates to cosmetic or dermatological preparations containing inorganic pigments coated with hydrophilic silica and nonionic emulsifiers.
  • decorative cosmetics derives from the Latin “decoratio” - the highlighting of the beautiful - with the help of dyes, individual parts of the body, especially on the face, are highlighted and color inconsistencies are lessened Give appearance, refresh pale skin, compensate for color irregularities of the skin as well as emphasize eyes and lips.
  • a particular embodiment is the so-called Foundation.
  • Foundation is liquid or semisolid make-up that is mostly skin colored and applied to the face. They give a uniform, healthy, tinted or reddish appearance. Their color is usually obtained by a mixture of pigments from the group of inorganic white, colored and / or colored pigments.
  • the prior art requires relatively large amounts of these inorganic whitening, coloring and / or colored pigments. The larger the proportion of these pigments in the preparation, the better the skin appearance is balanced. Redness and other visual skin irregularities are masked.
  • a disadvantage of the prior art is the fact that foundations based on O / W emulsions (oil-in-water emulsions) can only be formulated with a relatively low pigment content, since with an increasing content of insoluble particles or pigments Instabilities or rheological changes of the emulsion, such as decrease in viscosity occur.
  • the desired decorative effects can only be achieved with sufficiently high amounts of pigments.
  • a cosmetic O / W emulsion containing a) at least one pigment from the group of inorganic whitening, dyeing and / or colored pigments which are coated with hydrophilic silica and
  • Particularly advantageous inorganic pigments which are coated with hydrophilic silica are the so-called “Primrose” pigments from Miyoshi Kasei Inc.
  • Preferred representatives of these silica-coated, hydrophilic, inorganic pigments have an average particle size of 1 .0 - 3.0 ⁇ m and have the following typical composition: 85.0-90.0% of inorganic pigments as the core and 10.0-15.0% of silicon dioxide (silica) as coating.
  • Typical metal oxides used in the inorganic pigments are titanium dioxide, iron oxide, chromium oxide and manganese oxide.
  • the different oxidation states of the metal oxide, especially the iron oxide, are responsible for the different colors, with the following classes, which are summarized in the so-called Color Index: Cl 77499 (black), Cl 77491 (red), Cl 77492 (yellow).
  • Cl 77499 black
  • Cl 77491 red
  • Cl 77492 yellow
  • These inorganic whitening, coloring and / or coloring pigments are combined with each other in the present invention to obtain a certain hue.
  • Cosmetic or dermatological preparations according to the invention preferably contain from 0.01 to 50% by weight, preferably from 0.05 to 30% by weight, particularly preferably from 0.1 to 20% by weight, of one or more of the pigments of the invention Group of inorganic whitening, coloring or colored pigments which are coated with hydrophilic silica, based on the total composition of the preparations.
  • nonionic emulsifiers are preferably a) partial fatty acid esters and fatty acid esters of polyhydric alcohols and their ethoxylated derivatives (eg glyceryl monostearates, sorbitan stearates, glyceryl stearate citrate, sucrose stearates) and b) ethoxylated fatty alcohols and fatty acids, preferably PEG-100 stearate, PEG-40 Steatrate, ceteareth-20, ceteth-20, steareth-20, ceteareth-12, ceteth-12, steareth-12 and esters of mono-, oligo- or polysaccharides with fatty acids, preferably cetearyl glucoside and methyl glucose distearate. c) fatty acid esters of oligoglycerols and mixtures of the substances mentioned under a), b) and c).
  • polyhydric alcohols and their ethoxylated derivatives egly
  • glyceryl stearate citrate polyglyceryl-3-methyl glucose distearate, polyglyceryl stearate and / or PEG-40 stearate.
  • PGMS polyglyceryl-3-methyl-glucose distearate
  • PEG-40 Stearate is available, inter alia, from Evonik Industries under the trade name TEGO Acid S40P.
  • Glyceryl stearate citrate (2-hydroxy-1,2,3-propanetricarboxylic acid 1,2,3-propanetriol monoocta-decanoate, INCI Glyceryl Stearate Citrate) is the citric acid ester of glyceryl stearate and is available from several manufacturers under the names Imwitor 370 or 372 , Polyglyceryl-10 stearate is available under the trade designation Polyaldo 10-1 -S from Lonza.
  • Cosmetic or dermatological preparations according to the invention preferably comprise 0.01-20% by weight, preferably 0.05-10% by weight, particularly preferably 0.1-5% by weight of one or more of the nonionic emulsifiers according to the invention, based on the total composition of the preparations, in particular one or more substances selected from one or more of the groups mentioned under a) to c), most preferably one or more substances selected from the group glyceryl stearate citrate, polyglyceryl-3-methylglucose distearate , Polyglyceryl-10 stearate and / or PEG-40 stearate.
  • Emulsions are advantageous dosage forms in the sense of the present invention, e.g. in the form of a cream, a lotion, a cosmetic milk are advantageous and contain e.g. Fats, oils, waxes and / or other fatty substances, as well as water and one or more emulsifiers, as they are commonly used for such a type of formulation.
  • the cosmetic or dermatological preparation in the sense of the present invention is a solution or emulsion or dispersion, it is possible to use as solvent:
  • Oils such as triglycerides of capric or caprylic acid, silicone oils;
  • Fats, waxes and other natural and synthetic fats preferably esters of fatty acids with lower C-number alcohols, e.g. with isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with alkanoic acids of low C number or with
  • Fatty acids three dimensionally crosslinked organopolysiloxanes such as siloxane nelastomer;
  • Alcohols, diols or polyols of low C number, and their ethers preferably ethanol, isopropanol, propylene glycol, glycerol, hexanediol, octanediol, ethylhexylglycerol, glycerylcaprylate, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, butylene glycol, methylpropanediol, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products.
  • the oil phase of the emulsions, oleogels or hydrodispersions or lipodispersions in the context of the present invention is advantageously selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms, from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms.
  • ester oils can then advantageously be selected from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, cetearyl isononanoate, isodecyl neopentanoate, 2-ethylhexyl palmitate, 2 Ethyl hexyl laurate, 2-hexyl decyl stearate, 2-octyl dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate and also synthetic, semi-synthetic and natural mixtures of such esters,
  • the oil phase can be advantageously selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols, and the fatty acid triglycerides, in particular the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 12 to 18 carbon atoms.
  • the fatty acid triglycerides can be advantageously selected from the group of synthetic, semi-synthetic and natural oils, e.g. Olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil and the like.
  • Usual colorants which are suitable for use as cosmetic or dermatological compositions in the context of the present invention are lipophilic dyes (eg Sudan Red, DB & C Red 17, DB & C Green 6, ⁇ -carotene, Sudan brown, DB & C Yellow 1 1, DB & C Violet 2, DB & C Orange 5 or Annatto), hydrophilic dyes (eg beetroot juice or methylene blue), pearlescent pigments and blends of such colorants.
  • lipophilic dyes eg Sudan Red, DB & C Red 17, DB & C Green 6, ⁇ -carotene, Sudan brown, DB & C Yellow 1 1, DB & C Violet 2, DB & C Orange 5 or Annatto
  • hydrophilic dyes eg beetroot juice or methylene blue
  • pearlescent pigments eg beetroot juice or methylene blue
  • the pigments may be white or colored, goniochromatic or non-goniochromatic, inorganic and / or organic, coated or uncoated.
  • the inorganic pigments include titanium dioxide which is optionally surface-treated, zirconium oxide (ZrO 2), zinc oxide (ZnO), iron oxide (eg Fe 2 O 3), silicon oxide (SiO 2), manganese (eg MnO), aluminum ( Al 2 O 3), or ceria (eg, Ce 2 O 3), and iron oxide, chromium oxide, manganese violet, ultramarine blue, chromium hydrate, and iron blue
  • the pearlescent pigments may be exemplified by white pearlescent pigments such as mica coated with titanium or bismuth oxychloride, colored pearlescent pigments such as titanium mica with iron oxides, titanium mica especially iron blue or chromium oxide mica, titanium mica having an organic pigment of the type mentioned above and pearlescent pigments based on Bismuth oxychloride.
  • the pigments can also be used advantageously in the form of commercially available oily or aqueous predispersions. Dispersants and / or solubilizers may advantageously be added to these predispersions.
  • silicone elastomers according to the invention are crosslinked, optionally substituted organopolysiloxanes.
  • the crosslinking may have been carried out by means of all common methods and crosslinkers.
  • silicone elastomers can be used in powder form, such as, for example, e.g. EP-9701 or EP 9801 to Dow Corning.
  • the preparation contains one or more fillers.
  • the fillers are selected from the group of the compounds nylon 6/12, silica, silica dimethyl silylates, aluminum starch octenylsuccinates, dimethicone crosspolymer, dimethicone / vinyldimethicone crosspolymer, methyl methacrylate large polymer, talc, rice starch and all starch derivatives, lauroyl lysines , Magnesium silicate and / or polymethylsilsesquioxane.
  • the aqueous phase of the preparations according to the invention may advantageously contain one or more thickening agents which may be advantageously selected from the group of silica, aluminum silicates, polysaccharides or their derivatives, e.g. Hyaluronic acid, xanthan gum, cellulose ethers such as e.g.
  • Hydroxypropylmethylcellu- lose particularly advantageous from the group of polyacrylates, preferably a polyacrylate from the group of so-called Carbopols, for example, Carbopols types 980, 981, 1382, 2984, 5984, Ultrez 10, ETD 2020, acrylates / C 10-30 alkyl acrylates Crosspolymer, sodium acrylate copolymer, carbomer, either individually or in combination.
  • Carbopols for example, Carbopols types 980, 981, 1382, 2984, 5984, Ultrez 10, ETD 2020, acrylates / C 10-30 alkyl acrylates
  • Crosspolymer sodium acrylate copolymer, carbomer, either individually or in combination.
  • Inventive formulations which z. B. known anti-wrinkle agents such as flavone glycosides (especially ⁇ -glycosyl rutin), coenzyme Q10, vitamin E and / or derivatives and the like, are particularly advantageous for the prophylaxis and treatment of cosmetic or dermatological skin lesions, as z. B. in skin aging such as dryness, roughness and formation of dryness lines, itching, reduced refatting (eg after washing), visible vasodilation (telangiectasia, cuperosis), slackness and development of wrinkles and fine lines, local hypo-, hypo- and false pigmentation (eg, age spots), increased susceptibility to mechanical stress (eg, cracking), and the like). Furthermore, they are advantageous against the appearance of dry or rough skin.
  • Preparations in the context of the present invention may preferably contain at least one further UV-A, UV-B and / or broad-spectrum filter substance.
  • the formulations may, although not necessary, optionally also contain one or more organic and / or inorganic pigments as UV filter substances, which may be present in the water and / or the oil phase.
  • ICI octocrylene
  • 2-ethylhexyl 2-hydroxybenzoate 2-ethylhexyl salicylate, octyl salicylate, INCI: octyl Salicylates
  • esters of cinnamic acid
  • UV-A filter substances for the purposes of the present invention are dibenzoylmeter derivatives, in particular 4- (tert-butyl) -4'-methoxydibenzoylmethane (CAS No. 70356-09-1), which has been sold by Givaudan under the trademark Parsol ® 1789 and sold by Merck under the trade name Eusolex® 9020.
  • UV filter substances in the context of the present invention are sulfonated, water-soluble UV filters, such as. B .:
  • Advantageous UV filter substances for the purposes of the present invention are also so-called broadband filters, i. Filter substances that absorb both UV-A and UV-B radiation.
  • Advantageous broadband filters or UV-B filter substances are, for example, triazine derivatives, such as. B.
  • Diethylhexylbutylamidotriazone (INCI: diethylhexylbutamidotriazone), which is available under the trade name UVASORB HEB from Sigma 3V;
  • An advantageous broadband filter in the context of the present invention is also the 2,2'-methyl-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol ), which is available under the trade name Tinosorb® M from CIBA-Chemikalien GmbH.
  • the lipophilic phase eg oils, waxes
  • thickeners, pigments and the aqueous phase are weighed in separately, the nonionic O / W emulsifier being added to the lipophilic phase (oil phase), while the anionic, water-soluble emulsifiers were added to the water phase.
  • the oil phase is heated to 75 ° C in a water bath to the emulsifier and to dissolve the coemulsifier.
  • the water phase is also heated to 75 ° C with stirring and then it is slowly added after the addition of the thickener phase with intensive stirring to the oil phase, wherein a coarse emulsion is formed.
  • the silica-coated inorganic pigments are intensively homogenized in a separate vessel in about 100 ml of a solution of glycerol and water with a high-speed mixer (eg an ESG wand) for about 2 minutes and then submerged to about 60 ° C warm emulsion Stirring added.
  • the emulsion is then homogenized a first time and then neutralized with sodium hydroxide solution to a pH of pH 6.5 - 7.3. After the emulsion has cooled to room temperature, a second homogenization is carried out.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to cosmetic and dermatological preparations containing a) at least one pigment from the group of inorganic white, coloured or multi-coloured pigments which are coated with hydrophilic silica and b) one or more non-ionic emulsifiers.

Description

Beschreibung  description
Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an anorganischen Pigmente, welche mit hydrophilem Silica beschichtet sind, und nichtionischen Cosmetic or dermatological preparations containing inorganic pigments coated with hydrophilic silica, and nonionic
Emulgatoren  emulsifiers
Die Erfindung betrifft kosmetische oder dermatologische Zubereitungen mit einem Gehalt an anorganischen Pigmenten, welche mit hydrophilem Silica beschichtet sind, und nichtionischen Emulgatoren. The invention relates to cosmetic or dermatological preparations containing inorganic pigments coated with hydrophilic silica and nonionic emulsifiers.
Der Wunsch, schön und attraktiv auszusehen, ist seit Tausenden von Jahren in den Menschen verwurzelt. Auch wenn das Schönheitsideal im Laufe der Zeit Wandlungen erfahren hat, so ist das Streben nach einem makellosen Äußeren, immer das Ziel der Menschen gewesen, da ein sympathisches Erscheinungsbild ihr Selbstwertgefühl und die Anziehungskraft auf ihre Mitmenschen erhöht. The desire to look beautiful and attractive has been rooted in people for thousands of years. Even though the ideal of beauty has undergone changes over time, the pursuit of an impeccable appearance has always been the goal of man, since a sympathetic appearance enhances their self-esteem and attraction to their fellow human beings.
Der Begriff der Dekorativen Kosmetik leitet vom lateinischen„decoratio" - das Hervorheben des Schönen - ab. Meist werden dabei mit Hilfe von Farbstoffen einzelne Körperpartien, insbesondere im Gesicht, hervorgehoben und farbliche Uneinheitlichkeiten abgemildert. Das Gesichts-Make-up soll der Gesichtshaut ein natürliches Aussehen verleihen, blasse Haut auffrischen, farbliche Unregelmäßigkeiten der Haut ausgleichen sowie Augen und Lippen besonders betonen. The term "decorative cosmetics" derives from the Latin "decoratio" - the highlighting of the beautiful - with the help of dyes, individual parts of the body, especially on the face, are highlighted and color inconsistencies are lessened Give appearance, refresh pale skin, compensate for color irregularities of the skin as well as emphasize eyes and lips.
Neben Gesichtspudern und Rouge als pulverförmigen Kosmetika sowie stiftförmigen Zubereitungen werden hierzu cremeförmige Präparate, wie Tagescremes und Creme-Make-up auf Emulsionsbasis oder Hydrodispersionsbasis verwendet. Eine besondere Ausführungsform ist die sogenannte Foundation. Als Foundation bezeichnet man dabei flüssige oder halbfeste Make-up-Präparate, die meist Hautfarben sind und auf das Gesicht aufgetragen werden. Sie verleihen ein gleichmäßiges, gesundes, getöntes oder rötliches Aussehen. Ihren Farbton erhalten diese Zubereitungen in der Regel durch eine Mischung aus Pigmenten aus der Gruppe der anorganischen Weiß-, Färb- und/oder Buntpigmente. Um ein gleichmäßiges Hautbild zu erzeugen, sind nach dem Stand der Technik relativ große Mengen an diesen anorganischen Weiß-, Färb- und/oder Buntpigmenten erforderlich. Je größer der Anteil dieser Pigmente in der Zubereitung ist, desto besser wird das Hautbild ausgeglichen. Rötungen und andere optische Hautunregelmäßigkeiten werden überdeckt. In addition to facial powders and rouge as powdered cosmetics and stick-shaped preparations cream-like preparations, such as day creams and cream make-up based on emulsion or hydrodispersion base are used. A particular embodiment is the so-called Foundation. Foundation is liquid or semisolid make-up that is mostly skin colored and applied to the face. They give a uniform, healthy, tinted or reddish appearance. Their color is usually obtained by a mixture of pigments from the group of inorganic white, colored and / or colored pigments. To a uniform To produce a skin appearance, the prior art requires relatively large amounts of these inorganic whitening, coloring and / or colored pigments. The larger the proportion of these pigments in the preparation, the better the skin appearance is balanced. Redness and other visual skin irregularities are masked.
Nachteilig am Stande der Technik ist jedoch der Umstand, dass Foundations auf der Basis von O/W-Emulsionen (ÖI-in-Wasser-Emulsionen) nur mit einem relativ geringen Pigmentgehalt formuliert werden können, da bei einem zunehmendem Gehalt an unlöslichen Partikeln oder Pigmenten Instabilitäten bzw rheologische Veränderungen der Emulsion, wie zum Beispiel Abnahme der Viskosität, auftreten. Auf der anderen Seite lassen sich jedoch die erwünschten dekorativen Effekte nur mit ausreichend hohen Mengen an Pigmenten erzielen. A disadvantage of the prior art, however, is the fact that foundations based on O / W emulsions (oil-in-water emulsions) can only be formulated with a relatively low pigment content, since with an increasing content of insoluble particles or pigments Instabilities or rheological changes of the emulsion, such as decrease in viscosity occur. On the other hand, however, the desired decorative effects can only be achieved with sufficiently high amounts of pigments.
Es war daher die Aufgabe der vorliegenden Erfindung, eine Foundation auf der Basis einer O/W-Emulsion zu entwickeln, die eine hohe Stabilität aufweist, sich gut auf der Haut verteilen lässt und nach dem Auftragen auf die Haut zu einem gleichmäßigen Hautbild führt und alle optischen Unregelmäßigkeiten wirkungsvoll überdeckt. It was therefore an object of the present invention to develop a foundation based on an O / W emulsion, which has a high stability, can be distributed well on the skin and after application to the skin leads to a uniform skin appearance and all optical irregularities effectively covered.
Überraschend gelöst wird die Aufgabe durch eine kosmetische O/W-Emulsion enthaltend a) mindestens ein Pigment aus der Gruppe der anorganischen Weiß-, Färb- und/oder Buntpigmente, welche mit hydrophilem Silica beschichtet sind und, The object is surprisingly achieved by a cosmetic O / W emulsion containing a) at least one pigment from the group of inorganic whitening, dyeing and / or colored pigments which are coated with hydrophilic silica and
b) einen oder mehrere nichtionische Emulgatoren. b) one or more nonionic emulsifiers.
Besonders vorteilhafte anorganische Pigmente, welche mit hydrophilem Silica beschichtet sind, stellen die sogenannten„Primrose" Pigmente von der Firma Miyoshi Kasei Inc. dar. Particularly advantageous inorganic pigments which are coated with hydrophilic silica are the so-called "Primrose" pigments from Miyoshi Kasei Inc.
Bevorzugte Vertreter dieser mit Silica beschichteten, hydrophilen, anorganischen Pigmente haben eine durchschnittlichen Teilchengröße von 1 .0 - 3.0 μηι und haben folgende typische Zusammensetzung: 85.0 - 90.0 % anorganische Pigmente als Kern und 10.0 - 15.0 % Silici- umdioxid (Silica) als Beschichtung. Preferred representatives of these silica-coated, hydrophilic, inorganic pigments have an average particle size of 1 .0 - 3.0 μm and have the following typical composition: 85.0-90.0% of inorganic pigments as the core and 10.0-15.0% of silicon dioxide (silica) as coating.
Typische Metalloxide, die in den anorganischen Pigmenten verwendet werden, sind Titandioxid, Eisenoxid, Chromoxid und Manganoxid. Die unterschiedliche Oxidationszustände des Metalloxids, vor allem des Eisenoxids, sind verantwortlich für die unterschiedliche Farbgebung, wobei es folgende Klassen gibt, die im sogenannten Color Index zusammengefasst werden: Cl 77499 (Schwarz), Cl 77491 (Rot), Cl 77492 (Gelb). Diese anorganischen Weiß-, Färb- und/oder Buntpigmente werden mit einander in der vorliegenden Erfindung kombiniert, um einen bestimmten Farbton zu erzielen. Bevorzugt enthalten kosmetische oder dermatologische Zubereitungen gemäß der Erfindung 0,01 - 50 Gew.-%, bevorzugt 0,05 - 30 Gew.-%, besonders bevorzugt 0,1 - 20 Gew.-% an einem oder mehreren der erfindungsgemäßen Pigmente aus der Gruppe der anorganischen Weiß-, Färb- oder Buntpigmente, welche mit hydrophilem Silica beschichtet sind, bezogen auf die Gesamtzusammensetzung der Zubereitungen. Typical metal oxides used in the inorganic pigments are titanium dioxide, iron oxide, chromium oxide and manganese oxide. The different oxidation states of the metal oxide, especially the iron oxide, are responsible for the different colors, with the following classes, which are summarized in the so-called Color Index: Cl 77499 (black), Cl 77491 (red), Cl 77492 (yellow). These inorganic whitening, coloring and / or coloring pigments are combined with each other in the present invention to obtain a certain hue. Cosmetic or dermatological preparations according to the invention preferably contain from 0.01 to 50% by weight, preferably from 0.05 to 30% by weight, particularly preferably from 0.1 to 20% by weight, of one or more of the pigments of the invention Group of inorganic whitening, coloring or colored pigments which are coated with hydrophilic silica, based on the total composition of the preparations.
Unter den nichtionischen Emulgatoren befinden sich vorzugsweise a) Partialfettsäureester und Fettsäureester mehrwertiger Alkohole und deren ethoxilierte Derivate (z. B. Glycerylmonostearate, Sorbitanstearate, Glycerylstearatcitrat Sucrose Stearate) und b) ethoxylierte Fettalkohole und Fettsäuren, bevorzugt PEG-100-Stearat, PEG-40-Stea- rat, Ceteareth-20, Ceteth-20, Steareth-20, Ceteareth-12, Ceteth-12, Steareth-12 sowie Ester aus Mono-, Oligo- oder Polysacchariden mit Fettsäuren, bevorzugt Cetearylglu- cosid und Methylglucosedistearat. c) Fettsäureester von Oligoglycerinen sowie Gemische aus den unter a), b) und c) bezeichneten Substanzen. Among the nonionic emulsifiers are preferably a) partial fatty acid esters and fatty acid esters of polyhydric alcohols and their ethoxylated derivatives (eg glyceryl monostearates, sorbitan stearates, glyceryl stearate citrate, sucrose stearates) and b) ethoxylated fatty alcohols and fatty acids, preferably PEG-100 stearate, PEG-40 Steatrate, ceteareth-20, ceteth-20, steareth-20, ceteareth-12, ceteth-12, steareth-12 and esters of mono-, oligo- or polysaccharides with fatty acids, preferably cetearyl glucoside and methyl glucose distearate. c) fatty acid esters of oligoglycerols and mixtures of the substances mentioned under a), b) and c).
Besonders bevorzugt sind Glycerylstearatcitrat, Polyglyceryl-3 Methylglucosedistearat, Poly- glyceryl-10 Stearat und/oder PEG-40-Stearat. Particularly preferred are glyceryl stearate citrate, polyglyceryl-3-methyl glucose distearate, polyglyceryl stearate and / or PEG-40 stearate.
Ein bevorzugter Vertreter des„Polyglyceryl-3 Methylglucosedistearat" (PGMS) ist unter der Warenbezeichnung Tego® Care 450 von der Firma Evonik Industries erhältlich. A preferred representative of "polyglyceryl-3-methyl-glucose distearate" (PGMS) is available under the trade name Tego® Care 450 from Evonik Industries.
PEG-40 Stearat ist unter anderem bei der Firma Evonik Industries unter dem Handelsnamen TEGO Acid S40 P erhältlich. PEG-40 Stearate is available, inter alia, from Evonik Industries under the trade name TEGO Acid S40P.
Glycerylstearatcitrat, (2-Hydroxy-1 ,2,3-propantricarbonsäure-1 ,2,3-propantriolmonoocta-de- canoat, INCI Glyceryl Stearate Citrate) ist der Citronensäureester des Glycerylstearates und wird von verschiedenen Herstellern unter den Bezeichnungen Imwitor 370 oder 372 angeboten. Polyglyceryl-10 Stearat ist unter der Warenbezeichnung Polyaldo 10-1 -S von der Firma Lonza erhältlich. Glyceryl stearate citrate, (2-hydroxy-1,2,3-propanetricarboxylic acid 1,2,3-propanetriol monoocta-decanoate, INCI Glyceryl Stearate Citrate) is the citric acid ester of glyceryl stearate and is available from several manufacturers under the names Imwitor 370 or 372 , Polyglyceryl-10 stearate is available under the trade designation Polyaldo 10-1 -S from Lonza.
Bevorzugt enthalten kosmetische oder dermatologische Zubereitungen gemäß der Erfindung 0,01 - 20 Gew.-%, bevorzugt 0,05 - 10 Gew.-%, besonders bevorzugt 0,1 - 5 Gew.-% an einem oder mehreren der erfindungsgemäßen nichtionischen Emulgatoren, bezogen auf die Gesamtzusammensetzung der Zubereitungen, insbesondere eine oder mehrere Substanzen, gewählt aus einer oder mehrerer der unter a) bis c) genannten Gruppen, ganz besonders bevorzugt eine oder mehrere Substanzen, gewählt aus der Gruppe Glycerylstearatcitrat, Poly- glyceryl-3-Methylglucose Distearat, Polyglyceryl-10 Stearat und/oder PEG-40-Stearat. Cosmetic or dermatological preparations according to the invention preferably comprise 0.01-20% by weight, preferably 0.05-10% by weight, particularly preferably 0.1-5% by weight of one or more of the nonionic emulsifiers according to the invention, based on the total composition of the preparations, in particular one or more substances selected from one or more of the groups mentioned under a) to c), most preferably one or more substances selected from the group glyceryl stearate citrate, polyglyceryl-3-methylglucose distearate , Polyglyceryl-10 stearate and / or PEG-40 stearate.
Emulsionen sind vorteilhafte Darreichungsformen im Sinne der vorliegenden Erfindung, z.B. in Form einer Creme, einer Lotion, einer kosmetischen Milch sind vorteilhaft und enthalten z.B. Fette, Öle, Wachse und/oder andere Fettkörper, sowie Wasser und einen oder mehrere Emulgatoren, wie sie üblicherweise für einen solchen Typ der Formulierung verwendet werden. Emulsions are advantageous dosage forms in the sense of the present invention, e.g. in the form of a cream, a lotion, a cosmetic milk are advantageous and contain e.g. Fats, oils, waxes and / or other fatty substances, as well as water and one or more emulsifiers, as they are commonly used for such a type of formulation.
Sofern die kosmetische oder dermatologische Zubereitung im Sinne der vorliegenden Erfindung eine Lösung oder Emulsion oder Dispersion darstellt, können als Lösungsmittel verwendet werden: If the cosmetic or dermatological preparation in the sense of the present invention is a solution or emulsion or dispersion, it is possible to use as solvent:
Wasser oder wässrige Lösungen  Water or aqueous solutions
Öle, wie Triglyceride der Caprin- oder der Caprylsäure, Siliconöle;  Oils, such as triglycerides of capric or caprylic acid, silicone oils;
Fette, Wachse und andere natürliche und synthetische Fettkörper, vorzugsweise Ester von Fettsäuren mit Alkoholen niedriger C-Zahl, z.B. mit Isopropanol, Propylenglykol o- der Glycerin, oder Ester von Fettalkoholen mit Alkansäuren niedriger C-Zahl oder mit Fats, waxes and other natural and synthetic fats, preferably esters of fatty acids with lower C-number alcohols, e.g. with isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with alkanoic acids of low C number or with
Fettsäuren, drei dimensional vernetzte Organopolysiloxane wie zum Beispiel Siloxa- nelastomer; Fatty acids, three dimensionally crosslinked organopolysiloxanes such as siloxane nelastomer;
Alkohole, Diole oder Polyole niedriger C-Zahl, sowie deren Ether, vorzugsweise Ethanol, Isopropanol, Propylenglykol, Glycerin, Hexandiol, Octandiol, Ethylhexylglycerin, Glycerylcaprylat, Ethylenglykol, Ethylenglykolmonoethyl- oder -monobutylether, Propy- lenglykolmonomethyl, Butylenglykol, Methylpropandiol, -monoethyl- oder -monobutylether, Diethylenglykolmonomethyl- oder -monoethylether und analoge Produkte.  Alcohols, diols or polyols of low C number, and their ethers, preferably ethanol, isopropanol, propylene glycol, glycerol, hexanediol, octanediol, ethylhexylglycerol, glycerylcaprylate, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, butylene glycol, methylpropanediol, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products.
Insbesondere werden Gemische der vorstehend genannten Lösungsmittel verwendet. Bei alkoholischen Lösungsmitteln kann Wasser ein weiterer Bestandteil sein. Die Ölphase der Emulsionen, Oleogele bzw. Hydrodispersionen oder Lipodispersionen im Sinne der vorliegenden Erfindung wird vorteilhaft gewählt aus der Gruppe der Ester aus gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkancarbonsäuren einer Kettenlänge von 3 bis 30 C-Atomen und gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkoholen einer Kettenlänge von 3 bis 30 C-Atomen, aus der Gruppe der Ester aus aromatischen Carbonsäuren und gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkoholen einer Kettenlänge von 3 bis 30 C-Atomen. Solche Esteröle können dann vorteilhaft gewählt werden aus der Gruppe Isopropylmyristat, Isopropylpalmitat, Isopropylstearat, Isopropyloleat, n-Butylstearat, n-Hexyllaurat, n-Decy- loleat, Isooctylstearat, Isononylstearat, Isononylisononanoat, Cetearylisononanoat, Isodecyl- neopentanoat, 2-Ethylhexylpalmitat, 2-Ethylhexyllaurat, 2-Hexyldecylstearat, 2-Octyldodecyl- palmitat, Oleyloleat, Oleylerucat, Erucyloleat, Erucylerucat sowie synthetische, halbsynthetische und natürliche Gemische solcher Ester, z.B. Jojobaöl. In particular, mixtures of the abovementioned solvents are used. For alcoholic solvents, water can be another ingredient. The oil phase of the emulsions, oleogels or hydrodispersions or lipodispersions in the context of the present invention is advantageously selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms, from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms. Such ester oils can then advantageously be selected from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, cetearyl isononanoate, isodecyl neopentanoate, 2-ethylhexyl palmitate, 2 Ethyl hexyl laurate, 2-hexyl decyl stearate, 2-octyl dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate and also synthetic, semi-synthetic and natural mixtures of such esters, for example jojoba oil.
Ferner kann die Ölphase vorteilhaft gewählt werden aus der Gruppe der verzweigten und unverzweigten Kohlenwasserstoffe und -wachse, der Silkonöle, der Dialkylether, der Gruppe der gesättigten oder ungesättigten, verzweigten oder unverzweigten Alkohole, sowie der Fettsäuretriglyceride, namentlich der Triglycerinester gesättigter und/oder ungesättigter, verzweigter und/oder unverzweigter Alkancarbonsäuren einer Kettenlänge von 8 bis 24, insbesondere 12 bis 18 C-Atomen. Die Fettsäuretriglyceride können beispielsweise vorteilhaft gewählt werden aus der Gruppe der synthetischen, halbsynthetischen und natürlichen Öle, z.B. Olivenöl, Sonnenblumenöl, Sojaöl, Erdnussöl, Rapsöl, Mandelöl, Palmöl, Kokosöl, Palm- kernöl und dergleichen mehr. Furthermore, the oil phase can be advantageously selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols, and the fatty acid triglycerides, in particular the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 12 to 18 carbon atoms. For example, the fatty acid triglycerides can be advantageously selected from the group of synthetic, semi-synthetic and natural oils, e.g. Olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil and the like.
Übliche Farbmittel, welche sich für die Verwendung als kosmetische oder dermatologische Zusammensetzungen im Sinne der vorliegenden Erfindung eignen, sind lipophile Farbstoffe (z.B. Sudanrot, DB&C Red 17, DB&C Green 6, ß-Carotin, Sudanbraun, DB&C Yellow 1 1 , DB&C Violet 2, DB&C Orange 5 oder Annatto) , hydrophile Farbstoffe (z.B. Rote Beete-Saft oder Methylenblau), Perlglanzpigmenten sowie Abmischungen aus solchen Farbmitteln. Usual colorants which are suitable for use as cosmetic or dermatological compositions in the context of the present invention are lipophilic dyes (eg Sudan Red, DB & C Red 17, DB & C Green 6, β-carotene, Sudan brown, DB & C Yellow 1 1, DB & C Violet 2, DB & C Orange 5 or Annatto), hydrophilic dyes (eg beetroot juice or methylene blue), pearlescent pigments and blends of such colorants.
Die Pigmente können weiß oder farbig, goniochromatisch oder nicht goniochromatisch, anorganisch und/oder organisch, beschichtet oder nicht beschichtet sein. Zu den anorganischen Pigmenten, die angegeben werden können, gehören Titandioxid, das optional oberflächenbehandelt ist, Zirconiumoxid (Zr02), Zinkoxid (ZnO), Eisenoxid (z.B. Fe203), Siliciumoxid (Si02), Mangans (z. B. MnO), Aluminiums (AI203), oder Ceroxid (z. B. Ce203), sowie Eisenoxid, Chromoxid, Manganviolett, Ultramarinblau, Chromhydrat und Eisenblau Die Perlglanzpigmente können unter weißen Perlglanzpigmenten, wie Glimmer, der mit Titan oder mit Bismutoxidchlorid überzogen ist, farbigen Perlglanzpigmenten, wie Titanglimmer mit Eisenoxiden, Titanglimmer mit vor allem Eisenblau oder Chromoxid, Titanglimmer mit einem organischen Pigment vom oben erwähnten Typ und Perlglanzpigmente auf der Basis von Bismutoxidchlorid ausgewählt werden. The pigments may be white or colored, goniochromatic or non-goniochromatic, inorganic and / or organic, coated or uncoated. Among the inorganic pigments which may be mentioned include titanium dioxide which is optionally surface-treated, zirconium oxide (ZrO 2), zinc oxide (ZnO), iron oxide (eg Fe 2 O 3), silicon oxide (SiO 2), manganese (eg MnO), aluminum ( Al 2 O 3), or ceria (eg, Ce 2 O 3), and iron oxide, chromium oxide, manganese violet, ultramarine blue, chromium hydrate, and iron blue The pearlescent pigments may be exemplified by white pearlescent pigments such as mica coated with titanium or bismuth oxychloride, colored pearlescent pigments such as titanium mica with iron oxides, titanium mica especially iron blue or chromium oxide mica, titanium mica having an organic pigment of the type mentioned above and pearlescent pigments based on Bismuth oxychloride.
Die Pigmente können vorteilhaft im Sinne der vorliegenden Erfindung auch in Form kommerziell erhältlicher öliger oder wässriger Vordispersionen zur Anwendung kommen. Diesen Vordispersionen können vorteilhaft Dispergierhilfsmittel und/oder Solubilisations-vermittler zugesetzt sein. Within the meaning of the present invention, the pigments can also be used advantageously in the form of commercially available oily or aqueous predispersions. Dispersants and / or solubilizers may advantageously be added to these predispersions.
Bei den erfindungsgemäßen Silikonelastomeren handelt es sich um vernetzte, ggf. substituierte Organopolysiloxane. Die Vernetzung kann mittels aller gängigen Verfahren und Vernetzern durchgeführt worden sein. Besonders vorteilhaft im Sinne der vorliegenden Erfindung können Silikonelastomeren in Puder Form eingesetzt werden, wie beispielsweise z.B. EP- 9701 oder EP-9801 von Dow Corning. The silicone elastomers according to the invention are crosslinked, optionally substituted organopolysiloxanes. The crosslinking may have been carried out by means of all common methods and crosslinkers. Particularly advantageous for the purposes of the present invention, silicone elastomers can be used in powder form, such as, for example, e.g. EP-9701 or EP 9801 to Dow Corning.
Ferner ist es erfindungsgemäß vorteilhaft, wenn die Zubereitung eine oder mehrere Füllstoffe enthält. Erfindungsgemäß bevorzugt werden die Füllstoffe gewählt aus der Gruppe der Verbindungen Nylon 6/12, Silica, Silica Dimethyl Silylate, Aluminiumstärkeoctenylsuccinate, Di- methicon-Crosspolymer, Dimethicon/Vinyldimethicon-Crosspolymer, Methylmethacrylat- Grosspolymer, Talkum, Reisstärke und alle Stärke Derivate, Lauroyl Lysine, Magnesium Silikat und/oder Polymethylsilsesquioxane. Furthermore, it is advantageous according to the invention if the preparation contains one or more fillers. According to the invention, the fillers are selected from the group of the compounds nylon 6/12, silica, silica dimethyl silylates, aluminum starch octenylsuccinates, dimethicone crosspolymer, dimethicone / vinyldimethicone crosspolymer, methyl methacrylate large polymer, talc, rice starch and all starch derivatives, lauroyl lysines , Magnesium silicate and / or polymethylsilsesquioxane.
Die wässrige Phase der erfindungsgemäßen Zubereitungen enthält gegebenenfalls vorteilhaft ein oder mehrere Verdickungsmittel, welches oder welche vorteilhaft gewählt werden können aus der Gruppe Siliciumdioxid, Aluminiumsilikate, Polysaccharide bzw. deren Derivate, z.B. Hyaluronsäure, Xanthangummi, Celluloseether wie z.B. Hydroxypropylmethylcellu- lose, besonders vorteilhaft aus der Gruppe der Polyacrylate, bevorzugt ein Polyacrylat aus der Gruppe der sogenannten Carbopole, beispielsweise Carbopole der Typen 980, 981 , 1382, 2984, 5984, Ultrez 10, ETD 2020, Acrylates/C 10-30 Alkyl Acrylates Crosspolymer, Sodium Acrylates Copolymer, Carbomer, jeweils einzeln oder in Kombination. The aqueous phase of the preparations according to the invention may advantageously contain one or more thickening agents which may be advantageously selected from the group of silica, aluminum silicates, polysaccharides or their derivatives, e.g. Hyaluronic acid, xanthan gum, cellulose ethers such as e.g. Hydroxypropylmethylcellu- lose, particularly advantageous from the group of polyacrylates, preferably a polyacrylate from the group of so-called Carbopols, for example, Carbopols types 980, 981, 1382, 2984, 5984, Ultrez 10, ETD 2020, acrylates / C 10-30 alkyl acrylates Crosspolymer, sodium acrylate copolymer, carbomer, either individually or in combination.
Erfindungsgemäße Rezepturen, welche z. B. bekannte Anti-Falten Wirkstoffe wie Flavon-gly- coside (insbesondere α-Glycosylrutin), Coenzym Q10, Vitamin E und/oder Derivate und dergleichen enthalten, eignen sich insbesondere vorteilhaft zur Prophylaxe und Behandlung kosmetischer oder dermatologischer Hautveränderungen, wie sie z. B. bei der Hautalterung auftreten (wie beispielsweise Trockenheit, Rauigkeit und Ausbildung von Trockenheitsfält- chen, Juckreiz, verminderte Rückfettung (z. B. nach dem Waschen), sichtbare Gefäßerweiterungen (Teleangiektasien, Cuperosis), Schlaffheit und Ausbildung von Falten und Fältchen, lokale Hyper-, Hypo- und Fehlpigmentierungen (z. B. Altersflecken), vergrößerte Anfälligkeit gegenüber mechanischem Stress (z. B. Rissigkeit) und dergleichen). Weiterhin vorteilhaft eignen sie sich gegen das Erscheinungsbild der trockenen bzw. rauen Haut. Inventive formulations which z. B. known anti-wrinkle agents such as flavone glycosides (especially α-glycosyl rutin), coenzyme Q10, vitamin E and / or derivatives and the like, are particularly advantageous for the prophylaxis and treatment of cosmetic or dermatological skin lesions, as z. B. in skin aging such as dryness, roughness and formation of dryness lines, itching, reduced refatting (eg after washing), visible vasodilation (telangiectasia, cuperosis), slackness and development of wrinkles and fine lines, local hypo-, hypo- and false pigmentation (eg, age spots), increased susceptibility to mechanical stress (eg, cracking), and the like). Furthermore, they are advantageous against the appearance of dry or rough skin.
Zubereitungen im Sinne der vorliegenden Erfindung können vorzugsweise mindestens eine weitere UV-A-, UV-B- und/oder Breitbandfiltersubstanz enthalten. Die Formulierungen können, obgleich nicht notwendig, gegebenenfalls auch ein oder mehrere organische und/oder anorganische Pigmente als UV-Filtersubstanzen enthalten, welche in der Wasser- und/oder der Ölphase vorliegen können. Preparations in the context of the present invention may preferably contain at least one further UV-A, UV-B and / or broad-spectrum filter substance. The formulations may, although not necessary, optionally also contain one or more organic and / or inorganic pigments as UV filter substances, which may be present in the water and / or the oil phase.
Besonders vorteilhafte bei Raumtemperatur flüssige UV-Filtersubstanzen im Sinne der vorliegenden Erfindung sind 2-Ethylhexyl-2-cyano-3,3-diphenylacrylat (INCI: Octocrylene), 2- Ethylhexyl-2-hydroxybenzoat (2-Ethylhexylsalicylat, Octylsalicylat, INCI: Octyl Salicylate) und Ester der Zimtsäure, vorzugsweise 4-Methoxyzimtsäure(2-ethylhexyl)ester (2-Ethylhe- xyl-4-methoxycinnamat, INCI: Octyl Methoxycinnamate). Particularly advantageous UV filter substances which are liquid at room temperature for the purposes of the present invention are 2-ethylhexyl 2-cyano-3,3-diphenylacrylate (INCI: octocrylene), 2-ethylhexyl 2-hydroxybenzoate (2-ethylhexyl salicylate, octyl salicylate, INCI: octyl Salicylates) and esters of cinnamic acid, preferably 4-methoxycinnamic acid (2-ethylhexyl) ester (2-ethylhexyl-4-methoxycinnamate, INCI: octyl methoxycinnamate).
Vorteilhafte UV-A-Filtersubstanzen im Sinne der vorliegenden Erfindung sind Dibenzoylmet- handerivate, insbesondere das 4-(tert.-Butyl)-4'-methoxydibenzoylmethan (CAS-Nr. 70356- 09-1 ), welches von Givaudan unter der Marke Parsol® 1789 und von Merck unter der Handelsbezeichnung Eusolex® 9020 verkauft wird. Advantageous UV-A filter substances for the purposes of the present invention are dibenzoylmeter derivatives, in particular 4- (tert-butyl) -4'-methoxydibenzoylmethane (CAS No. 70356-09-1), which has been sold by Givaudan under the trademark Parsol ® 1789 and sold by Merck under the trade name Eusolex® 9020.
Vorteilhafte weitere UV-Filtersubstanzen im Sinne der vorliegenden Erfindung sind sulfo- nierte, wasserlösliche UV-Filter, wie z. B.: Advantageous further UV filter substances in the context of the present invention are sulfonated, water-soluble UV filters, such as. B .:
• Salze der 2-Phenylbenzimidazol-5-sulfonsäure, wie ihr Natrium-, Kalium- oder ihr Tri- ethanolammonium-Salz sowie die Sulfonsäure selbst mit der INCI Bezeichnung Phe- nylbenzimidazole Sulfonsäure (CAS. -Nr. 27503-81 -7), welches beispielsweise unter der Handelsbezeichnung Eusolex 232 bei Merck oder unter Neo Heliopan Hydro bei Haarmann & Reimer erhältlich ist;  Salts of 2-phenylbenzimidazole-5-sulfonic acid, such as its sodium, potassium or triethanolammonium salt, and the sulfonic acid itself with the INCI name phenylbenzimidazole sulfonic acid (CAS No. 27503-81 -7), which is available, for example, under the trade name Eusolex 232 from Merck or under Neo Heliopan Hydro from Haarmann &Reimer;
• 1 ,4-di(2-oxo-10-Sulfo-3-bornylidenmethyl)-Benzol (auch: 3,3'-(1 ,4-Phenylendimethyl- ene)-bis-(7,7-dimethyl-2-oxo-bicyclo-[2.2.1 ]hept-1 -ylmethan Sulfonsäure) und dessen Salze (besonders die entprechenden 10-Sulfato-verbindungen, insbesondere das entsprechende Natrium-, Kalium- oder Triethanolammonium-Salz), das auch als Benzol- 1, 4-di (2-oxo-10-sulfo-3-bornylidenemethyl) benzene (also: 3,3 '- (1,4-phenylenedimethylene) -bis (7,7-dimethyl-2-) oxo-bicyclo [2.2.1] hept-1-ylmethane sulfonic acid) and its salts (especially the corresponding 10-sulfato compounds, in particular the corresponding sodium, potassium or triethanolammonium salt), also known as benzene
1 ,4-di(2-oxo-3-bornylidenmethyl-10-sulfonsäure) bezeichnet wird. Benzol-1 ,4-di(2-oxo- 3-bornylidenmethyl-10-sulfonsäure) hat die INCI-Bezeichnung Terephtalidene Di- campher Sulfonsäure (CAS. -Nr.: 90457-82-2) und ist beispielsweise unter dem Handelsnamen Mexoryl SX von der Fa. Chimex erhältlich. 1, 4-di (2-oxo-3-bornylidenemethyl-10-sulfonic acid) is called. Benzene-1, 4-di (2-oxo) 3-bornylidenemethyl-10-sulfonic acid) has the INCI name Terephtalidene Di-sulfo Sulfonic Acid (CAS No. 90457-82-2) and is available, for example, under the trade name Mexoryl SX from Chimex.
Vorteilhafte UV-Filtersubstanzen im Sinne der vorliegenden Erfindung sind ferner sogenannte Breitbandfilter, d.h. Filtersubstanzen, die sowohl UV-A- als auch UV-B-Strahlung absorbieren. Advantageous UV filter substances for the purposes of the present invention are also so-called broadband filters, i. Filter substances that absorb both UV-A and UV-B radiation.
Vorteilhafte Breitbandfilter oder UV-B-Filtersubstanzen sind beispielsweise Triazinderivate, wie z. B. Advantageous broadband filters or UV-B filter substances are, for example, triazine derivatives, such as. B.
• 2,4-Bis-{[4-(2-Ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1 ,3,5-triazin (INCI: Aniso Triazin), welches unter der Handelsbezeichnung Tinosorb® S bei der CIBA-Chemikalien GmbH erhältlich ist;  2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI: aniso triazine), which available under the trade name Tinosorb® S from CIBA-Chemikalien GmbH;
• Diethylhexylbutylamidotriazon (INCI: Diethylhexylbutamidotriazone), welches unter der Handelsbezeichnung UVASORB HEB bei Sigma 3V erhältlich ist;  Diethylhexylbutylamidotriazone (INCI: diethylhexylbutamidotriazone), which is available under the trade name UVASORB HEB from Sigma 3V;
4,4',4"-(1 ,3,5-Triazin-2,4,6-triyltriimino)-tris-benzoesäure-tris(2-ethylhexylester), auch: 2,4,6-Tris-[anilino-(p-carbo-2'-ethyl-1 '-hexyloxy)]-1 ,3,5-triazin (INCI: Ethylhexyl Tria- zone), welches von der BASF Aktiengesellschaft unter der Warenbezeichnung U- VINUL® T 150 vertrieben wird.  4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester), also: 2,4,6-tris [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone), which is sold by BASF Aktiengesellschaft under the trade name U-VINUL® T 150.
Ein vorteilhafter Breitbandfilter im Sinne der vorliegenden Erfindung ist auch das 2,2'-Methy- len-bis-(6-(2H-benzotriazol-2-yl)-4-(1 ,1 ,3,3-tetramethylbutyl)-phenol), welches unter der Handelsbezeichnung Tinosorb® M bei der CIBA-Chemikalien GmbH erhältlich ist. An advantageous broadband filter in the context of the present invention is also the 2,2'-methyl-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol ), which is available under the trade name Tinosorb® M from CIBA-Chemikalien GmbH.
Die nachfolgenden Beispiele sollen die vorliegende Erfindung verdeutlichen, ohne sie einzuschränken. Alle Mengenangaben, Anteile und Prozentanteile sind, soweit nicht anders angegeben, auf das Gewicht und die Gesamtmenge bzw. auf das Gesamtgewicht der Zubereitungen bezogen. The following examples are intended to illustrate the present invention without limiting it. Unless indicated otherwise, all amounts, proportions and percentages are based on the weight and the total amount or on the total weight of the preparations.
Zur Herstellung von 1 Kilogramm der erfindungsgemäßen Emulsionen werden die lipophile Phase (z.B. Öle, Wachse), Verdicker, Pigmente und die wässrige Phase separat eingewogen, wobei der nichtionische O/W-Emulgator zur lipophilen Phase (Ölphase) zugegeben wird, während die anionischen, wasserlöslichen Emulgatoren in die Wasserphase gegeben wurden. Die Ölphase wird bis auf 75°C in einem Wasserbad erhitz, um den Emulgator und den Coemulgator zu lösen. Die Wasserphase wird ebenfalls bis auf 75°C unter Rühren erhitzt und danach wird sie nach der Zugabe der Verdickerphase unter intensivem Rühren langsam zur Ölphase hinzugegeben, wobei eine grobe Emulsion entsteht. Die Silica-be- schichteten anorganischen Pigmente werden in einem separaten Gefäß in ca. 100 ml einer Lösung aus Glycerin und Wassers mit einem hochtourigen Mixer (z.B. einem ESG Zauberstab) circa 2 Minuten intensiv homogenisiert und dann zur ca. 60 °C warmen Emulsion unter Rühren hinzugegeben. Die Emulsion wird dann ein erstes Mal homogenisiert und danach mit Natronlauge auf einen pH Wert von pH 6.5 - 7.3 neutralisiert. Nach Abkühlung der Emulsion auf Raumtemperatur erfolgt eine zweite Homogenisierung. To prepare 1 kilogram of the emulsions according to the invention, the lipophilic phase (eg oils, waxes), thickeners, pigments and the aqueous phase are weighed in separately, the nonionic O / W emulsifier being added to the lipophilic phase (oil phase), while the anionic, water-soluble emulsifiers were added to the water phase. The oil phase is heated to 75 ° C in a water bath to the emulsifier and to dissolve the coemulsifier. The water phase is also heated to 75 ° C with stirring and then it is slowly added after the addition of the thickener phase with intensive stirring to the oil phase, wherein a coarse emulsion is formed. The silica-coated inorganic pigments are intensively homogenized in a separate vessel in about 100 ml of a solution of glycerol and water with a high-speed mixer (eg an ESG wand) for about 2 minutes and then submerged to about 60 ° C warm emulsion Stirring added. The emulsion is then homogenized a first time and then neutralized with sodium hydroxide solution to a pH of pH 6.5 - 7.3. After the emulsion has cooled to room temperature, a second homogenization is carried out.
Zur Bestimmung der Lagerstabilität von den Pigmenten werden alle Emulsionsproben in verschraubten 30 mL Gläsern bei unterschiedlichen Temperaturen gelagert: bei Raumtemperatur (RT) (ca. 20°C), bei +40 °C, bei +50 °C sowie unter Wechseltemperaturbedingungen zwischen -10°C und +40°C. To determine the storage stability of the pigments, all emulsion samples are stored in screw-retained 30 mL glasses at different temperatures: at room temperature (RT) (about 20 ° C.), at + 40 ° C., at + 50 ° C. and under alternating temperature conditions between -10 ° C and + 40 ° C.
Die Stabilität wurde nach 7, 14, 21 und 30 Tagen (T) visuell bewertet. The stability was assessed visually after 7, 14, 21 and 30 days (T).
Beispielrezeptur/ RT +40 °C + 50°C W-10 °C/ Temperaturen 40°CExample recipe / RT + 40 ° C + 50 ° C W-10 ° C / Temperatures 40 ° C
1 a - Emulsion mit Poly- Stabil 30T Stabil 30T Stabil 30T Stabil 30T glyceryl-3 Methylglu- cose Distearate und 1 a - Emulsion with PolyStable 30T Stabil 30T Stabil 30T Stabil 30T glyceryl-3 methylglucose distearate and
Pigmenten  pigments
1 b - Emulsion 1 a Stabil 30T Stabil 30T Stabil 30T Stabil 30T ohne Piamente Nihiih El Iih Eltttconscemgaorenonscemgaorenuu-1 b - Emulsion 1 a Stable 30T Stable 30T Stable 30T Stable 30T without piamente N ihiih E l Iih E lttt conscem g ao r enonscem g ao r enuu
2a - Emulsion mit PEG- Stabil 30T Stabil 30T Stabil 30T Leichte In40 Stearate stabilität und Pigmenten 30T 2a - Emulsion with PEG-Stabil 30T Stabil 30T Stabil 30T Light In40 Stearate stability and pigments 30T
2b - Emulsion 2a Stabil 30T Stabil 30T Stabil 30T Stabil 30T ohne Piamente  2b - Emulsion 2a Stable 30T Stable 30T Stable 30T Stable 30T without Piamente
3a - Emulsion mit Gly- Stabil 30T Stabil 30T Leichte InstaStabil 30T cerylstearatcitrat und bilität 30T  3a - Emulsion with Gly-Stabil 30T Stabil 30T Light InstaStabil 30T ceryl stearate citrate and 30T
Pigmenten  pigments
3b - Emulsion 3a ohne Stabil 30T Stabil 30T Stabil 30T Stabil 30T Pigmenten  3b - Emulsion 3a without Stabil 30T Stabil 30T Stabil 30T Stabil 30T pigments
4a - Emulsion mit Stabil 30T SedimentaSedimentation Leichte InSodium Stearoyl Glutation der Pigder Pigmente stabilität mate mente ab 21 T ab 21 T 30T und Pigmenten  4a - Emulsion with Stable 30T Sedimenta Sedimentation Slight InSodium Stearoyl Glutation of Pigder Pigments Stability Mate ments from 21 T from 21 T 30T and Pigments
4b - Emulsion 4a Stabil 30T Stabil 30T Stabil 30T Stabil 30T ohne Piqmente  4b - Emulsion 4a Stable 30T Stable 30T Stable 30T Stable 30T without Piqmente
5a - Emulsion mit SoLeichte InSedimentaSedimentation Stabil 30T dium Cetearyl Sulfate stabilität tion der Pigder Pigmente  5a - Emulsion with SoLight InSedimenta Sedimentation Stable 30T dium Cetearyl Sulfate Stability of Pigder Pigments
und Pigmenten 30T mente ab 14T ab 14T  and pigments 30T from 14T from 14T
5b - Emulsion 5a Leichte InStabil 30T Stabil 30T Stabil 30T ohne Piamente stabilität  5b - Emulsion 5a Light InStable 30T Stabil 30T Stabil 30T without Piamente stability
30T  30T
„Stabil" bedeutet, dass keine oder nur geringe Phasentrennung, keine oder nur geringe Ölab- scheidung, keine visuell erkennbaren Inhomogenität der Pigmentverteilung auftritt.„Leichte Instabilität" bedeutet, dass es zu einer moderaten, sichtbaren Phasentrennung oder deutlich sichtbaren Ölabscheidung oder zu visuell erkennbaren Inhomogenität kommt. „Sedimentation der Pigmente" bedeutet, vollständige und sichtbare Sedimentation der Pigmente am Boden. "Stable" means no or little phase separation, little or no oil separation, no visually discernible inhomogeneity of the pigment distribution. "Light instability" means that there is a moderate, visible phase separation or clearly visible oil separation or visually discernible Inhomogeneity is coming. "Sedimentation of the pigments" means complete and visible sedimentation of the pigments on the soil.
Diese Experimente haben gezeigt, dass die Silica beschichtete anorganischen Pigmente Emulsionen durch die nichtionischen Emulgatoren stabilisiert wurden. These experiments have shown that the silica-coated inorganic pigments emulsions have been stabilized by the non-ionic emulsifiers.
Figure imgf000012_0001
Octyldodecanol 4
Figure imgf000012_0001
Octyldodecanol 4
Caprylic/Capric Triglyceride 4Caprylic / Capric Triglycerides 4
Stearylalkohol 2Stearyl alcohol 2
Phenoxyethanol 0.8Phenoxyethanol 0.8
Dicaprylyl Ether 4Dicaprylyl ether 4
Carbomer 0.1Carbomer 0.1
Glycerin 7Glycerol 7
Natronlauge (45%-ig) 0,13Sodium hydroxide solution (45%) 0.13
Silica beschichtete anorganischen Pigmente 6 [(Cl 77499, Cl 77491 , Cl 77891 , Cl 77492) Silica coated inorganic pigments 6 [(Cl 77499, Cl 77491, Cl 77891, Cl 77492)
+ Silica] - PRIMROSE  + Silica] - PRIMROSE
Wasser Ad 100  Water Ad 100
Figure imgf000013_0001
Beispielrezeptur 8 Gew.-%
Figure imgf000013_0001
Example recipe 8% by weight
Polyglyceryl-10 Stearat 1Polyglyceryl-10 Stearate 1
Glyceryl Stearate 2Glyceryl Stearate 2
Cetylalkohol 1Cetyl alcohol 1
Octyldodecanol 3Octyldodecanol 3
Cetearyl Isononanoate 4Cetearyl Isononanoate 4
C12-15 Alkylbenzoat 2C12-15 alkyl benzoate 2
Bis-Ethylhexyloxyphenolmethoxyphenyltria- 1 zin Bis-ethylhexyloxyphenolmethoxyphenyltria-1-zine
Octocrylen 5 Octocrylene 5
Phenoxyethanol 0.5Phenoxyethanol 0.5
Methylpropandiol 0.2Methylpropanediol 0.2
Xanthan Gum 0.2Xanthan gum 0.2
Acrylates/C 10-30 Alkyl Acrylate Crosspoly- 0.2 mer Acrylates / C 10-30 alkyl acrylate cross-poly-0.2 mer
Glycerin 6 Glycerol 6
Benzylalkohol 0.1Benzyl alcohol 0.1
Natronlauge (45%-ig) 0,13Sodium hydroxide solution (45%) 0.13
Silica beschichtete anorganischen Pigmente 5 Silica coated inorganic pigments 5
[(Cl 77499, Cl 77491 , Cl 77891 , Cl 77492) [(Cl 77499, Cl 77491, Cl 77891, Cl 77492)
+ Silica] - PRIMROSE + Silica] - PRIMROSE
Wasser Ad 100  Water Ad 100

Claims

Patentansprüche claims
Kosmetische oder dermatologische Zubereitungen enthaltend Contains cosmetic or dermatological preparations
a) Mindestens ein Pigment aus der Gruppe der anorganischen Weiß-, Färb- oder Buntpigmente, welche mit hydrophilem Silica beschichtet sind und a) at least one pigment from the group of inorganic white, colored or colored pigments, which are coated with hydrophilic silica and
b) einen oder mehrere nichtionischen Emulgatoren b) one or more nonionic emulsifiers
Zubereitungen nach Anspruch 1 , dadurch gekennzeichnet, dass der oder die nichtionischen Emulgatoren gewählt werden aus den Gruppen Preparations according to claim 1, characterized in that the one or more nonionic emulsifiers are selected from the groups
a) Partialfettsäureester und Fettsäureester mehrwertiger Alkohole und deren ethoxylierten Derivate (z. B. Glycerylmonostearat, Sorbitanstearat, Glyceryl- stearatcitrat, Sucrose Stearate)  a) Partial fatty acid esters and fatty acid esters of polyhydric alcohols and their ethoxylated derivatives (for example glyceryl monostearate, sorbitan stearate, glyceryl stearate citrate, sucrose stearate)
b) Ethoxylierte Fettalkohole bzw. Fettsäuren, bevorzugt PEG-100-Stearat, PEG- 40-Stearat, Ceteareth-20, Ceteth-20, Steareth-20, Ceteareth-12, Ceteth-12, Steareth-12 sowie Ester aus Mono-, Oligo- oder Polysacchariden mit Fettsäuren, bevorzugt Cetearylglucosid und Methylglucosedistearat.  b) ethoxylated fatty alcohols or fatty acids, preferably PEG-100 stearate, PEG-40 stearate, ceteareth-20, ceteth-20, steareth-20, ceteareth-12, ceteth-12, steareth-12 and also esters of mono-, Oligo- or polysaccharides with fatty acids, preferably cetearyl glucoside and methyl glucose distearate.
c) Fettsäureester von Oligoglycerinen sowie Gemischen aus den unter a), b) und c) bezeichneten Substanzen.  c) fatty acid esters of oligoglycerols and mixtures of the substances mentioned under a), b) and c).
Zubereitungen nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass der oder die nichtionischen Emulgatoren gewählt wird oder werden aus der Gruppe Glycerylstea- ratcitrat, Polyglyceryl-3 Methylglucosedistearat, Polyglyceryl-10 Stearat, PEG-40-Stea- rat. Preparations according to Claim 1 or 2, characterized in that the nonionic emulsifier (s) is / are selected from the group of glyceryl stearate citrate, polyglyceryl-3-methylglucose distearate, polyglyceryl-10-stearate, PEG-40 stearate.
Zubereitungen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass sie 0,01 - 20 Gew.-%, bevorzugt 0,05 - 10 Gew.-%, besonders bevorzugt 0,1 - 5 Gew.-% an einem oder mehreren der erfindungsgemäßen nichtionischen Emulgatoren enthalten, bezogen auf die Gesamtzusammensetzung der Zubereitungen, insbesondere eine oder mehrere Substanzen, gewählt aus einer oder mehrerer der unter a) bis c) genannten Gruppen, ganz besonders bevorzugt eine oder mehrere Substanzen, gewählt aus der Gruppe Glycerylstearatcitrat, Polyglyceryl-3 Methylglucosedistearat, Polyglyceryl-10 Stearat, und/oder PEG-40-Stearat. Preparations according to one of the preceding claims, characterized in that they contain 0.01 to 20 wt.%, Preferably 0.05 to 10 wt.%, Particularly preferably 0.1 to 5 wt.% Of one or more of the present invention nonionic emulsifiers, based on the total composition of the preparations, in particular one or more substances selected from one or more of the groups mentioned under a) to c), most preferably one or more substances selected from the group glyceryl stearate citrate, polyglyceryl-3 methyl glucose distearate , Polyglyceryl-10 stearate, and / or PEG-40 stearate.
Zubereitungen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass sie 0,01 - 50 Gew.-%, bevorzugt 0,05 - 30 Gew.-%, besonders bevorzugt 0,1 - 20 Gew.-% an einem oder mehreren der erfindungsgemäßen Pigment aus der Gruppe der anorganischen Weiß-, Färb- oder Buntpigmente, welche mit hydrophilem Silica beschichtet sind, enthalten, bezogen auf die Gesamtzusammensetzung der Zubereitungen. Preparations according to one of the preceding claims, characterized in that they are 0.01-50 wt .-%, preferably 0.05-30 wt .-%, particularly preferably 0.1-20 wt .-% of one or more of the inventive Pigment from the group of the inorganic whitening, coloring or colored pigments coated with hydrophilic silica, based on the total composition of the preparations.
6. Verwendung von nichtionischen Emulgatoren, wie in den vorstehenden Ansprüchen beschrieben, zur Verbesserung der Einarbeitbarkeit, von mit hydrophilem Silica beschichteter Metalloxidpartikel, wie in den vorstehenden Ansprüchen beschrieben. Use of nonionic emulsifiers as described in the preceding claims for improving the incorporation of hydrophilic silica-coated metal oxide particles as described in the preceding claims.
PCT/EP2018/050269 2017-02-27 2018-01-05 Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers WO2018153556A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP18700101.1A EP3585353A1 (en) 2017-02-27 2018-01-05 Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017203115.8A DE102017203115A1 (en) 2017-02-27 2017-02-27 Cosmetic or dermatological preparations containing inorganic pigments coated with hydrophilic silica and non-ionic emulsifiers
DE102017203115.8 2017-02-27

Publications (1)

Publication Number Publication Date
WO2018153556A1 true WO2018153556A1 (en) 2018-08-30

Family

ID=60937771

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2018/050269 WO2018153556A1 (en) 2017-02-27 2018-01-05 Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers

Country Status (3)

Country Link
EP (1) EP3585353A1 (en)
DE (1) DE102017203115A1 (en)
WO (1) WO2018153556A1 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009801A1 (en) 1978-10-10 1980-04-16 Sterling Drug Inc. Pharmaceutical compositions containing polycyclic cyanoketones
EP0009701A1 (en) 1978-09-28 1980-04-16 RHEIN-CHEMIE RHEINAU GmbH Sulfur-containing reaction products, method for their preparation and their use as lubricant additives
US20070104677A1 (en) * 2004-04-02 2007-05-10 Barbara Dold Preparation in the form of an emulsion
DE102009060148A1 (en) * 2009-12-23 2011-06-30 Beiersdorf AG, 20253 Cosmetic oil/water-emulsion, useful to obtain consistent skin texture after applying the emulsion on the skin, comprises pigment including inorganic white-, color- and/or multicolored pigments, and a pearlescent pigment
EP2364688A2 (en) * 2010-03-12 2011-09-14 Beiersdorf AG Cosmetic preparations with highly elastic texture
DE102014203868A1 (en) * 2014-03-04 2015-09-10 Evonik Degussa Gmbh Polyglycerol ester with particular oligomer distribution of polyglycerol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9616978D0 (en) 1996-08-13 1996-09-25 Tioxide Specialties Ltd Zinc oxide dispersions
US8277785B2 (en) 2005-12-13 2012-10-02 Avon Products, Inc. Cosmetic compositions with encapsulated pigments and a method for using
DE202006011834U1 (en) 2006-08-02 2006-09-28 Beiersdorf Ag Cosmetic preparation, useful in sun protective agent, comprises a benzoyl compound and hydrophilic micro pigments
DE102007055008A1 (en) 2007-11-14 2009-06-10 Coty Prestige Lancaster Group Gmbh Cosmetic product for the protection of the skin against environmental influences

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009701A1 (en) 1978-09-28 1980-04-16 RHEIN-CHEMIE RHEINAU GmbH Sulfur-containing reaction products, method for their preparation and their use as lubricant additives
EP0009801A1 (en) 1978-10-10 1980-04-16 Sterling Drug Inc. Pharmaceutical compositions containing polycyclic cyanoketones
US20070104677A1 (en) * 2004-04-02 2007-05-10 Barbara Dold Preparation in the form of an emulsion
DE102009060148A1 (en) * 2009-12-23 2011-06-30 Beiersdorf AG, 20253 Cosmetic oil/water-emulsion, useful to obtain consistent skin texture after applying the emulsion on the skin, comprises pigment including inorganic white-, color- and/or multicolored pigments, and a pearlescent pigment
EP2364688A2 (en) * 2010-03-12 2011-09-14 Beiersdorf AG Cosmetic preparations with highly elastic texture
DE102014203868A1 (en) * 2014-03-04 2015-09-10 Evonik Degussa Gmbh Polyglycerol ester with particular oligomer distribution of polyglycerol

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MIYOSHI EUROPE: "PRIMROSE Silica-Coated Pigments", 19 January 2017 (2017-01-19), pages 1 - 2, XP055453663, Retrieved from the Internet <URL:http://web.archive.org/web/20170119191944/http://miyoshiamerica.com/wp-content/uploads/2016/01/PRIMROSE-v1.3-LR-MAI.pdf> [retrieved on 20180222] *
MIYOSHI EUROPE: "Silica Beads Highly Pure Spherical Silic Beads", SAGE OPEN, 1 March 2015 (2015-03-01), Los Angeles, CA, XP055452897, Retrieved from the Internet <URL:http://www.cossma.com/fileadmin/all/cossma/Archiv/ProductInfo/COS1604_70SilicaBead.pdf> [retrieved on 20180221], DOI: 10.1177/2158244014536405 *

Also Published As

Publication number Publication date
EP3585353A1 (en) 2020-01-01
DE102017203115A1 (en) 2018-08-30

Similar Documents

Publication Publication Date Title
DE60001345T2 (en) At least one insoluble organic UV filter and an associative polymer containing emulsions
EP2111847A1 (en) Hydrocarbon mixtures and their use
EP1641904B1 (en) O/w emulsifier, o/w emulsion and applications thereof
DE10321147A1 (en) Stabilization of self-tanning products with layered silicates
EP1301166A1 (en) Rendering sunscreen agents visible on the skin
WO2018060018A1 (en) Use of dialkyl carbonates of branched alcohols as a dispersant
DE102008022434A1 (en) Cosmetic preparations containing hydrocarbons
DE102005051869A1 (en) Cosmetic preparation, useful e.g. for the protection of skin and (semi)mucous membrane against bacteria and/or virus, comprises violacein dye in combination with lipophilic and/or hydrophilic substances
EP1013262A2 (en) Cosmetic and dermatologic o/w-emulsions containing boron nitride
EP0887068B1 (en) Use of beeswax to increase the protection factor of cosmetic or dermatological sunscreens
DE19703471A1 (en) Cosmetic and dermatological sunscreen formulations containing triazine derivatives and butylene glycol diesters
EP0887069B1 (en) Use of synthetic beeswax to increase the protection factor of cosmetic or dermatological sunscreens
CH713170B1 (en) Cosmetic or dermatological preparation containing an aqueous and a lipophilic fish extract.
EP0935959B1 (en) Use of beeswax to increase the UVA protection factor of cosmetic or dermatologic sunscreens
EP0826360B1 (en) Use of dibenzoyl methane derivatives to attain or improve the solubility of triazine derivatives in oils
WO2018153556A1 (en) Cosmetic or dermatological preparations containing inorganic pigments which are coated with hydrophobic silica, and non-ionic emulsifiers
DE19723732A1 (en) Use of mono-acyl esters of isosorbide
AU2006297609A1 (en) Cosmetic compostions having increased color intensity and method for producing same
DE10035512A1 (en) Use of dyes in cosmetic and dermatological sunscreen formulations to make them visible on skin
DE202007019599U1 (en) Use of cosmetic or dermatological preparations containing glycyrrhetin and / or glycyrrhizin and 2,4-bis- {I4- (2-ethylhexyloxy) -2-hydroxyl-1-phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine Increase in the pigmentation of the human skin
EP0895775B1 (en) Lightprotection compositions containing inorganic pigments which are coated on their surface with UV filter substances
EP3570812B1 (en) Cosmetic preparations containing sphereic silicone materials coated with titanium dioxide and iron oxides and medium-chained aliphatic dioles
DE19900094B4 (en) Process for the preparation of sunscreen preparations comprising organic UV filters in solid, finely divided form
DE19645320A1 (en) Active agent combination for foaming pharmaceuticals and cosmetics
DE19830461A1 (en) Use of iron-titanium mixed oxides to enhance the sun protection performance of cosmetic or dermatological sunscreens

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 18700101

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2018700101

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载