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WO2018141313A3 - Uses of fgf-4 compounds - Google Patents

Uses of fgf-4 compounds Download PDF

Info

Publication number
WO2018141313A3
WO2018141313A3 PCT/CN2018/083256 CN2018083256W WO2018141313A3 WO 2018141313 A3 WO2018141313 A3 WO 2018141313A3 CN 2018083256 W CN2018083256 W CN 2018083256W WO 2018141313 A3 WO2018141313 A3 WO 2018141313A3
Authority
WO
WIPO (PCT)
Prior art keywords
fgf
compounds
prevention
treatment
specifically
Prior art date
Application number
PCT/CN2018/083256
Other languages
French (fr)
Other versions
WO2018141313A2 (en
WO2018141313A9 (en
Inventor
Hao Wu
Zhe Wang
Dan HAN
Fang Zhang
Xiaoli Chen
Rasmus Joergensen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Priority to PCT/CN2018/083256 priority Critical patent/WO2018141313A2/en
Publication of WO2018141313A2 publication Critical patent/WO2018141313A2/en
Publication of WO2018141313A9 publication Critical patent/WO2018141313A9/en
Publication of WO2018141313A3 publication Critical patent/WO2018141313A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Provided are uses of FGF-4 compounds. More specifically, provided are uses of FGF-4 compounds in the prevention and/or treatment of metabolic disorders.
PCT/CN2018/083256 2018-04-17 2018-04-17 Uses of fgf-4 compounds WO2018141313A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/083256 WO2018141313A2 (en) 2018-04-17 2018-04-17 Uses of fgf-4 compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/083256 WO2018141313A2 (en) 2018-04-17 2018-04-17 Uses of fgf-4 compounds

Publications (3)

Publication Number Publication Date
WO2018141313A2 WO2018141313A2 (en) 2018-08-09
WO2018141313A9 WO2018141313A9 (en) 2018-09-07
WO2018141313A3 true WO2018141313A3 (en) 2019-02-21

Family

ID=63039362

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2018/083256 WO2018141313A2 (en) 2018-04-17 2018-04-17 Uses of fgf-4 compounds

Country Status (1)

Country Link
WO (1) WO2018141313A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111944035B (en) * 2019-05-14 2022-08-12 温州医科大学 FGF4 and its applications

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003012053A2 (en) * 2001-08-01 2003-02-13 New York University Identification of receptor and heparin binding sites in fgf4 by structure-based mutagenesis
WO2011158125A2 (en) * 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
CN102971001A (en) * 2009-08-14 2013-03-13 阿勒根公司 Methods of treating cancer using growth factor retargeted endopeptidases
KR101490017B1 (en) * 2013-03-14 2015-02-09 건국대학교 산학협력단 Medium Composition for Establishing Novel Epiblast Stem Cell and Method for Establishing Novel Epiblast Stem Cell Using Thereof
WO2015171928A2 (en) * 2014-05-07 2015-11-12 Joslin Diabetes Center, Inc. Methods and compositions for induction of ucp1 expression

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003012053A2 (en) * 2001-08-01 2003-02-13 New York University Identification of receptor and heparin binding sites in fgf4 by structure-based mutagenesis
CN102971001A (en) * 2009-08-14 2013-03-13 阿勒根公司 Methods of treating cancer using growth factor retargeted endopeptidases
WO2011158125A2 (en) * 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
KR101490017B1 (en) * 2013-03-14 2015-02-09 건국대학교 산학협력단 Medium Composition for Establishing Novel Epiblast Stem Cell and Method for Establishing Novel Epiblast Stem Cell Using Thereof
WO2015171928A2 (en) * 2014-05-07 2015-11-12 Joslin Diabetes Center, Inc. Methods and compositions for induction of ucp1 expression

Also Published As

Publication number Publication date
WO2018141313A2 (en) 2018-08-09
WO2018141313A9 (en) 2018-09-07

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