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WO2016009095A1 - Tissus textiles fonctionnels - Google Patents

Tissus textiles fonctionnels Download PDF

Info

Publication number
WO2016009095A1
WO2016009095A1 PCT/ES2015/070328 ES2015070328W WO2016009095A1 WO 2016009095 A1 WO2016009095 A1 WO 2016009095A1 ES 2015070328 W ES2015070328 W ES 2015070328W WO 2016009095 A1 WO2016009095 A1 WO 2016009095A1
Authority
WO
WIPO (PCT)
Prior art keywords
endorphin
textile
textile fabric
bioactive molecule
fabric
Prior art date
Application number
PCT/ES2015/070328
Other languages
English (en)
Spanish (es)
Inventor
Ander Aldekoa Imaz
Original Assignee
Nabari Textil, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nabari Textil, S.L. filed Critical Nabari Textil, S.L.
Publication of WO2016009095A1 publication Critical patent/WO2016009095A1/fr

Links

Classifications

    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
    • D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
    • D06M15/15—Proteins or derivatives thereof

Definitions

  • the present invention falls within the field of materials, in particular the field of textile fibers or materials, in particular the invention relates to those textile materials or textile fibers used for the manufacture of functional textile elements comprising at least one molecule.
  • the present invention relates to a fabric made from textile fibers comprising at least one biologically active molecule, as well as to the textile garment made from said fabric.
  • the present invention also relates to a process for the manufacture of textile fabrics object of the invention comprising the bioactive molecule.
  • it refers to the application of at least one peptide, such as an opioid neurotransmitter of the endorphin type, in a cotton-based fabric, using a pipette with an optimized solution and concentration.
  • the present invention also relates to the use of said textile fabrics to manufacture textile garments that produce in the individual that they carry a feeling of general well-being.
  • the present invention thus provides a practical and simple solution that reports well-being in the users or patients who wear the garments as it had not been seen in the state of the art to date.
  • the effects it produces in the users of these tissues, the application of these molecules consist in the deceleration of the growth of cancer cells, promote the feeling of well-being, increase relaxation and inhibit the pain, and on the other hand produce feelings of placidity, joy, pleasure, desire to live and good humor, about people who are in contact with the tissue in question.
  • the procedures of ennoblement can be divided into purely mechanical and wet.
  • the liquids used are mainly water and, to a lesser extent, solvents, as well as liquefied ammonia gas.
  • Another important element is water vapor.
  • a large number of chemical products, dyes and chemical auxiliary agents are used.
  • ES2245795 discloses a composition
  • a composition comprising a peptide or a deposition adjuvant protein with a high affinity with the fibers or a surface, and a functional agent bound / adsorbed to the peptide or the adjuvant protein of the deposition, wherein said deposition peptide or protein is cellulose or the binding domain thereof, and said functional agent is selected from a perfume, an encapsulated perfume, a photoprotective agent, a soil-releasing polymer, a dirt repellent agent, a compound Fabric softener, an insecticide, a fungicide, antioxidants or pigment fixatives.
  • a functional agent in the context of this invention is a compound that provides a desirable effect for a fiber, fabric or surface not for the individual wearing it.
  • patent ES2087996 discloses a method for applying an insecticide to a fibrous textile material, characterized by encapsulating the insecticide within microcapsules of a substance that is a food, to which insects or their larvae are attracted. , and joining the microcapsules to the fibers of the material by means of a binding agent that does not prevent the release of the insecticide when the microcapsules are devoured.
  • composition comprises a polymer consisting of polyethyleneimine, a neutralizer of the bad smell consisting of an aliphatic aldehyde and an aqueous carrier, wherein said composition is practically free of any material that could dirty or stain fabrics.
  • US2008175991 discloses a method of manufacturing a coated cellulose textile, whereby a silk peptide is polymerized as in a building block to develop a silk peptide / building nanoparticle block, said nanoparticles are then used to cover the textile.
  • the resulting textile exhibits a high level of wrinkle recovery angle and / or resistance to breakage, all without the use of N-methylol compounds, including ureas and formaldehydes. In this case the advantage is over the fabric again.
  • WO2012131745 discloses a binder (which comprises sulfamic acid, ammonium sulfamate and ammonium sulfate) and the production process of fabrics containing cyclodextrins fixed with the binder. More precisely, the present invention makes it possible to fix a binder to natural, synthetic or artificial fibers, and by means of thermal processes fix cyclodextrins with the same binder, giving rise to suitable tissues to incorporate active ingredients and to free them in time. Peculiar characteristics of said binder are its abilities to interact with various types of tissues, regardless of their composition, and with several types of cyclodextrin.
  • This patent application discloses a method for treating spider silk filament, for use as a thread or composition in the manufacture of cosmetics, medical elements, textiles, and industrial applications, where the spider silk filament, from genetically modified organisms, it is treated with at least one component selected from the group consisting of vitamins, hormones, antioxidants, chelating agents, antibiotics, preservatives, fragrances, dyes, pigments, magnetic nanoparticles, nanocrystals, adhesion enhancers cellular, thermal insulators, shrinkage agents and cosmetic, medical or dermatological active substances. Fabrics obtained by this method are stronger, biocompatible, biodegradable and have superior thermal conductivity.
  • the treated spider silk filament can also be applied in an oil-petticoat or water-in-oil protective cream that is hypoallergenic and ensures firmer skin, but has no effect directly on the skin from the woven garment.
  • JPH09158041 discloses a method of obtaining clothing, such as underwear sufficiently capable of masking body odor due to perspiration, etc., without imparting an unpleasant sensation to a user by impregnating the clothing with a perfume precursor capable of producing a perfume component by hydrolysis.
  • the solution proposed by this patent is that the functional clothing is obtained by impregnating a fibrous material or a knitted fabric that constitutes the clothing with a perfume precursor such as a glycoside of a perfume, a glyceride or a peptide derivative.
  • the perfume precursor is preferably impregnated in an amount of 0.01-20% by weight.
  • the clothing or the fibrous material can be impregnated even with an enzyme capable of breaking down the perfume precursor to regulate the amount of an aroma released.
  • KR20040063730 Another patent of the next state of the art is KR20040063730.
  • This patent application discloses a functional textile that contains functional medical materials that are characterized by stimulating the immune system and the lymphatic system to control functions of vital importance, which has anti-cancer property, for disease prevention, which has the function of disease recovery, vital rhythm control, prevent aging and increased autoimmunity.
  • the functional medical materials are ribonucleic acid, oligosaccharides, chitosan, polysaccharide, amino acid, oligopeptides, peptideglycans, probiotics of useful microorganisms, functional plants and an algae extract.
  • patent KR20040064170 The last patent detected by the researchers of the present invention is patent KR20040064170.
  • This patent application is related to the previous one and discloses a functional cotton that contains functional medical materials and is characterized by stimulating the immune system and the lymphatic system to control the function of vital importance, which has anti-cancer property, disease prevention , which has the function of disease recovery, vital rhythm control, preventing aging and increasing autoimmunity.
  • Functional medical materials are ribonucleic acid, oligosaccharides, chitosan, polysaccharide, amino acid, oligopeptides, peptidoglycans, probiotics of useful microorganisms, functional plants and an algae extract.
  • Figure 1. Shows a mass spectrum in which a defined peak is reflected in a range between 3464-3465 Daltons characteristic of ⁇ -endorphin that allows it to be used as a control measure to track the presence of the compound in the tissue in the following days.
  • Figure 2. Shows a mass spectrum in which triplicates of 1 cm 2 tissue sample embedded with 2 ⁇ g / ⁇ l of B-endorphin are reflected, after 6h of exposure to controlled room temperature ( ⁇ 22.5 ⁇ c).
  • the tissue sample was treated as follows: Extraction by incubation with ACN: H 2 0 (1: 1) for 30 minutes at a controlled temperature of 22.52C. After incubation, it has been dried in a centrifugal desiccator, and the sample has been resuspended in 30 ⁇ . TFA 0.1% in water. The sample has been analyzed by splashing after desalting by R2R3 column (reverse phase, similar to C18 / C8).
  • Figure 4. Shows a mass spectrum in which triplicates of 1 cm 2 tissue sample embedded with 2 ⁇ g / ⁇ l of B-endorphin are reflected, after 48h of exposure to controlled room temperature ( ⁇ 22.5 ⁇ c). The tissue sample was treated in the same manner as Figure 2.
  • Figure 5. Shows a mass spectrum in which triplicates of 1 cm 2 tissue sample embedded with 2 ⁇ g / ⁇ l of B-endorphin are reflected, after 72h of exposure to controlled room temperature ( ⁇ 22.5 ⁇ c). The tissue sample was treated in the same manner as Figure 2.
  • Figure 6. Shows a mass spectrum in which triplicates of 1 cm 2 tissue sample embedded with 2 ⁇ g / ⁇ l of B-endorphin are reflected, after 10 days of exposure to controlled room temperature ( ⁇ 22.5 ⁇ c). The tissue sample was treated in the same manner as Figure 2.
  • textile fibers are understood regardless of the set of filaments or strands that can be used to form threads and with them fabrics, either by spinning or by other physical or chemical processes.
  • textile fibers are the basic structures of textile fabrics.
  • Textile fiber is considered any material whose length is much greater than its diameter and which can be spun.
  • textile fabric is considered to be the fabric made from textile fibers, that is, the textile product as a result of weaving textile threads, filaments or fibers.
  • textile garment is considered to be any final material obtained from the textile fabric object of the present invention that will be placed in contact with the user's skin.
  • bioactive molecule is considered to be any compound, molecular entity, ingredient or active agent whatever its origin - human, animal, vegetable, chemical or other - to which an appropriate activity beneficial to health is attributed and / or promote the feeling of well-being, increase relaxation and inhibit pain or produce feelings of placidity.
  • the invention relates to those textile materials or textile fibers used for the manufacture of functional textile fabrics comprising at least one biologically active molecule.
  • the biologically active molecule incorporated in the textile tissue is preferably a peptide, such as an opioid neurotransmitter of the endorphin type. More preferably ⁇ -endorphin.
  • Beta endorphin is an endogenous opioid hormone and neurotransmitter that is produced in the central nervous system. It acts primarily as a moderator of pain, reducing the transmission and effectiveness of sensory stimuli. Its receptors are located along the central and peripheral nervous system and are called opioid receptors, specifically ⁇ receptors. When the neurotransmitter is attached to the receptor it causes Supra peripheral spinal analgesia that results, among other effects, in a dilation of blood vessels, euphoria and sedation. It has great influence on the immune system. Leukocytes are extremely sensitive to endorphins, for which they have specific receptors. Endorphins increase the production and efficacy of T cells, which keep viruses, bacteria and cancer cells at bay and also stimulate the synthesis of endogenous antioxidants.
  • the present invention relates to a fabric made from textile fibers comprising at least one biologically active molecule, as well as to the textile garment made from said fabric.
  • the present invention also relates to a process for the manufacture of textile fabrics object of the invention comprising the bioactive molecule.
  • it refers to the application of at least one peptide, such as an opioid neurotransmitter of the endorphin type, in a cotton-based fabric, using a pipette with an optimized solution and concentration.
  • the present invention also relates to the use of said textile fabrics to manufacture textile garments that produce in the individual that they carry a feeling of general well-being.
  • the present invention therefore provides a practical and simple solution that reports well-being in the users or patients wearing the garments made from the tissue impregnated with a concentration of Beta endorphins.
  • the effects it produces on the users of these tissues, the application of these molecules consist of the slowdown of the growth of cancer cells, promote the feeling of well-being, increase relaxation and inhibit pain, and on the other hand produce feelings of placidity, joy , pleasure, desire to live and good humor, about people who are in contact with the tissue in question.
  • the concentration of ⁇ -endorphin is 0.1 to 500 ⁇ g / ⁇ L in H 2 0 and preferably 2 ⁇ g / ⁇ L of ⁇ -endorphin in H 2 0. This concentration is easily detected by a MALDI spectrometer. TOF Bruker Autoflex III Smartbeam, so that it can be verified that the textile fabric effectively comprises endorphin.
  • a textile fabric comprising a composition of at least one bioactive molecule that is ⁇ -endorphin in which the composition of the bioactive molecule is from 0.1 to 500 ⁇ g / ⁇ L of ⁇ -endorphin in H 2 0 and preferably 2 ⁇ g / ⁇ L of ⁇ -endorphin in H 2 0.
  • the textile fabric is a natural textile fabric selected from the group consisting of cotton, wool, silk, linen, hemp or biso, or artificial textile fabric selected from the group consisting of polyester, nylon, rayon, elastane, Taffeta or gauze.
  • the textile fabric is cotton.
  • the textile fabric of step a.-) is a natural textile fabric selected from the group consisting of cotton, wool, silk, linen, hemp or biso, or artificial textile fabric selected from the group consisting of polyester, nylon, rayon, elastane, taffeta or gauze.
  • the textile fabric is cotton.
  • the application of step b.-) is carried out with a device selected from the group consisting of pipette, swab, dropper, etc.
  • it is done with an automatic pipette, with solid phase extraction by means of reverse-phase Zip-Tip ® tips.
  • the application occurs directly in the fabric, so that it is absorbed by the tissue, the molecule being attached to the fibers of the textile fabric itself.
  • the process object of the present invention is characterized in that the addition of ⁇ -endorphin from step b.-) is carried out with an automatic pipette.
  • the process object of the present invention is characterized in that the addition of ⁇ -endorphin of step b.-) is carried out by atomizing a solution with the bioactive molecule on the tissue, waiting a few minutes to its absorption
  • ⁇ -endorphin from step b.- is performed at a concentration of 2ug ⁇ ⁇ -endorphin L H 2 0.
  • Another aspect of the present invention is a textile garment suitable for absorbing and releasing a bioactive molecule of the ⁇ -endorphin type that is obtained by the process of the present invention.
  • the aforementioned textile garment is suitable for absorbing and releasing a bioactive molecule of the ⁇ -endorphin type and is selected from the group consisting of dressings, gauze, sheets and clothing.
  • Another aspect of the present invention is the use of the textile fabric object of the present invention to manufacture a textile garment suitable for absorbing and releasing a bioactive molecule of the ⁇ -endorphin type.
  • EXAMPLE 1 Test of adhesion or fixation of ⁇ -endorphin to textile fabric.
  • the amount charged was 7 ⁇ , with elution in 0.5 ⁇ matrix (synapine acid, 10 mg / ml, in ACN: 0.1% TFA [70:30]).

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  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)

Abstract

la présente invention concerne un tissu textile confectionné à partir de fibres textiles, qui comprend au moins une molécule biologiquement active. La présente invention concerne également un procédé de fabrication des tissus textiles objets de l'invention, lesquels comprennent au moins un peptide tel qu'un neurotransmetteur opiacé du type β-endorphine. La présente invention concerne en outre l'utilisation desdits tissus tissés pour fabriquer des vêtements en textiles qui produisent chez l'individu qui les porte une sensation de bien-être général.
PCT/ES2015/070328 2014-07-16 2015-04-21 Tissus textiles fonctionnels WO2016009095A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP201431073 2014-07-16
ES201431073A ES2518765B2 (es) 2014-07-16 2014-07-16 Tejidos textiles funcionales

Publications (1)

Publication Number Publication Date
WO2016009095A1 true WO2016009095A1 (fr) 2016-01-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2015/070328 WO2016009095A1 (fr) 2014-07-16 2015-04-21 Tissus textiles fonctionnels

Country Status (2)

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ES (1) ES2518765B2 (fr)
WO (1) WO2016009095A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107641956A (zh) * 2017-09-08 2018-01-30 安徽龙盛纺织科技有限公司 一种雪纺面料压绉印花方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019087124A1 (fr) * 2017-11-01 2019-05-09 Clexio Biosciences Ltd. Structures fibreuses finies et leur procédés d'utilisation et de préparation

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2005260A (en) 1932-12-30 1935-06-18 Atlas Powder Co Press mechanism
ES2087996T3 (es) 1990-01-18 1996-08-01 Cpc International Inc Tratamiento de materiales textiles.
WO2003103550A2 (fr) * 2002-06-08 2003-12-18 Ian Robert Thomson Systeme d'administration de medicament ou de composition augmentant le bien-etre
KR20040063730A (ko) 2003-01-08 2004-07-14 손영석 기능성 원단
KR20040064170A (ko) 2003-01-09 2004-07-16 손영석 기능성 솜
EP1498113A1 (fr) * 2003-07-17 2005-01-19 L'oreal Utilisation de béta-endorphine et/ou d'agents exercant une activité béta-endorphine-like en cosmétique et dermatologie
DE10329685A1 (de) * 2003-07-02 2005-01-20 Cognis Deutschland Gmbh & Co. Kg Mikrokapseln (XXV)
ES2245795T3 (es) 1996-07-01 2006-01-16 Unilever N.V. Composicion detergente.
US20080175991A1 (en) 2007-01-22 2008-07-24 The Hong Kong Polytechnic University Cellulosic fabric with silk peptide/building block nanopolymer
MX2012003293A (es) 2009-09-18 2012-04-30 Procter & Gamble Composiciones refrescantes que comprenden polimeros que absorben el mal olor y neutralizadores del mal olor.
US20120238942A1 (en) * 2009-12-04 2012-09-20 Michael Horstmann Transdermal therapeutic System for the Administration of Peptides
WO2012131745A1 (fr) 2011-03-31 2012-10-04 GIANIS S.r.L. Liant et processus de production de tissus contenant des cyclodextrines fixées par ledit liant
WO2013147590A2 (fr) 2012-03-27 2013-10-03 Essaidi Jalila Procédé pour le traitement de filament de soie d'araignée pour utiliser comme fil ou composition dans la fabrication de produits cosmétiques, médicaux, textiles ou dans des applications industrielles comme des tissus de cellules bio-artificielles ou de la peau artificielle à base de soie d'araignée (recombinée)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780073B1 (fr) * 1998-06-19 2000-09-01 Dim Sa Textile bio-actif comportant dans ses fibres de la proteine de soie et des microcapsules de produit actif
EP2444549A1 (fr) * 2010-10-20 2012-04-25 Stazione Sperimentale per la Seta Matériaux textiles dotés d'une protection bioactive

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2005260A (en) 1932-12-30 1935-06-18 Atlas Powder Co Press mechanism
ES2087996T3 (es) 1990-01-18 1996-08-01 Cpc International Inc Tratamiento de materiales textiles.
ES2245795T3 (es) 1996-07-01 2006-01-16 Unilever N.V. Composicion detergente.
WO2003103550A2 (fr) * 2002-06-08 2003-12-18 Ian Robert Thomson Systeme d'administration de medicament ou de composition augmentant le bien-etre
KR20040063730A (ko) 2003-01-08 2004-07-14 손영석 기능성 원단
KR20040064170A (ko) 2003-01-09 2004-07-16 손영석 기능성 솜
DE10329685A1 (de) * 2003-07-02 2005-01-20 Cognis Deutschland Gmbh & Co. Kg Mikrokapseln (XXV)
EP1498113A1 (fr) * 2003-07-17 2005-01-19 L'oreal Utilisation de béta-endorphine et/ou d'agents exercant une activité béta-endorphine-like en cosmétique et dermatologie
US20080175991A1 (en) 2007-01-22 2008-07-24 The Hong Kong Polytechnic University Cellulosic fabric with silk peptide/building block nanopolymer
MX2012003293A (es) 2009-09-18 2012-04-30 Procter & Gamble Composiciones refrescantes que comprenden polimeros que absorben el mal olor y neutralizadores del mal olor.
US20120238942A1 (en) * 2009-12-04 2012-09-20 Michael Horstmann Transdermal therapeutic System for the Administration of Peptides
WO2012131745A1 (fr) 2011-03-31 2012-10-04 GIANIS S.r.L. Liant et processus de production de tissus contenant des cyclodextrines fixées par ledit liant
WO2013147590A2 (fr) 2012-03-27 2013-10-03 Essaidi Jalila Procédé pour le traitement de filament de soie d'araignée pour utiliser comme fil ou composition dans la fabrication de produits cosmétiques, médicaux, textiles ou dans des applications industrielles comme des tissus de cellules bio-artificielles ou de la peau artificielle à base de soie d'araignée (recombinée)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107641956A (zh) * 2017-09-08 2018-01-30 安徽龙盛纺织科技有限公司 一种雪纺面料压绉印花方法

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Publication number Publication date
ES2518765B2 (es) 2015-03-05
ES2518765A1 (es) 2014-11-05

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