WO2013016529A3 - Disk diffusion assay for oritavancin - Google Patents
Disk diffusion assay for oritavancin Download PDFInfo
- Publication number
- WO2013016529A3 WO2013016529A3 PCT/US2012/048329 US2012048329W WO2013016529A3 WO 2013016529 A3 WO2013016529 A3 WO 2013016529A3 US 2012048329 W US2012048329 W US 2012048329W WO 2013016529 A3 WO2013016529 A3 WO 2013016529A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- assay
- disk diffusion
- oritavancin
- diffusion assay
- polysorbate
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 5
- 238000009792 diffusion process Methods 0.000 title abstract 2
- VHFGEBVPHAGQPI-MYYQHNLBSA-N oritavancin Chemical compound O([C@@H]1C2=CC=C(C(=C2)Cl)OC=2C=C3C=C(C=2O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O[C@@H]2O[C@@H](C)[C@H](O)[C@@](C)(NCC=4C=CC(=CC=4)C=4C=CC(Cl)=CC=4)C2)OC2=CC=C(C=C2Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]2C(=O)N[C@@H]1C(N[C@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@@H](O)[C@H](C)O1 VHFGEBVPHAGQPI-MYYQHNLBSA-N 0.000 title 1
- 229960001607 oritavancin Drugs 0.000 title 1
- 108010006945 oritavancin Proteins 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 229940068968 polysorbate 80 Drugs 0.000 abstract 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9446—Antibacterials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention is directed to a disk diffusion assay for determining susceptibility of bacteria to a glycopeptide antibiotic. The assay includes improvements over conventional assays due to the inclusion of polysorbate 80 and Span 80 in the antibacterial solution used to impregnate paper disks used in the assay.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES12817566.8T ES2613806T3 (en) | 2011-07-26 | 2012-07-26 | Diffusion test with oritavancin disc |
| EP12817566.8A EP2737077B1 (en) | 2011-07-26 | 2012-07-26 | Disk diffusion assay for oritavancin |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161511608P | 2011-07-26 | 2011-07-26 | |
| US61/511,608 | 2011-07-26 | ||
| US201261642099P | 2012-05-03 | 2012-05-03 | |
| US61/642,099 | 2012-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2013016529A2 WO2013016529A2 (en) | 2013-01-31 |
| WO2013016529A3 true WO2013016529A3 (en) | 2013-04-04 |
Family
ID=47597512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2012/048329 WO2013016529A2 (en) | 2011-07-26 | 2012-07-26 | Disk diffusion assay for oritavancin |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8815535B2 (en) |
| EP (1) | EP2737077B1 (en) |
| ES (1) | ES2613806T3 (en) |
| WO (1) | WO2013016529A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3038620B1 (en) * | 2015-07-09 | 2019-05-24 | Biomerieux | METHOD FOR DETECTING A PRESENCE OR ABSENCE OF AT LEAST ONE FIRST INHIBITION AREA |
| CN108712909A (en) | 2016-02-18 | 2018-10-26 | 梅琳塔治疗公司 | Oritavancin preparation |
| KR102189833B1 (en) * | 2018-07-04 | 2020-12-14 | 연세대학교 산학협력단 | Media for disk diffusion method for evaluating susceptibility to antibiotics |
| CN113249431B (en) * | 2021-05-13 | 2022-10-04 | 吉林农业大学 | A kind of penicillin G residue test piece in milk, preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4448534A (en) * | 1978-03-30 | 1984-05-15 | American Hospital Corporation | Antibiotic susceptibility testing |
| US6103228A (en) * | 1997-05-09 | 2000-08-15 | Agraquest, Inc. | Compositions and methods for controlling plant pests |
| US6153400A (en) * | 1999-03-12 | 2000-11-28 | Akzo Nobel N.V. | Device and method for microbial antibiotic susceptibility testing |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840684A (en) | 1994-01-28 | 1998-11-24 | Eli Lilly And Company | Glycopeptide antibiotic derivatives |
-
2012
- 2012-07-26 US US13/559,060 patent/US8815535B2/en active Active
- 2012-07-26 ES ES12817566.8T patent/ES2613806T3/en active Active
- 2012-07-26 EP EP12817566.8A patent/EP2737077B1/en active Active
- 2012-07-26 WO PCT/US2012/048329 patent/WO2013016529A2/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4448534A (en) * | 1978-03-30 | 1984-05-15 | American Hospital Corporation | Antibiotic susceptibility testing |
| US6103228A (en) * | 1997-05-09 | 2000-08-15 | Agraquest, Inc. | Compositions and methods for controlling plant pests |
| US6153400A (en) * | 1999-03-12 | 2000-11-28 | Akzo Nobel N.V. | Device and method for microbial antibiotic susceptibility testing |
Non-Patent Citations (2)
| Title |
|---|
| FRANCIS F. ARHIN ET AL.: "Effect of Polysorbate 80 on Oritavancin Binding to Plastic Surfaces: Implications for Susceptibility Testing", ANTIMICROB AGENTS CHEMOTHER., vol. 52, no. 5, May 2008 (2008-05-01), pages 1597 - 1603, XP055142789 * |
| See also references of EP2737077A4 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2737077A4 (en) | 2014-12-03 |
| EP2737077A2 (en) | 2014-06-04 |
| ES2613806T3 (en) | 2017-05-26 |
| US8815535B2 (en) | 2014-08-26 |
| WO2013016529A2 (en) | 2013-01-31 |
| EP2737077B1 (en) | 2016-11-16 |
| US20130029371A1 (en) | 2013-01-31 |
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