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WO2012053011A3 - Compositions ophthalmiques comprenant de la brinzolamide - Google Patents

Compositions ophthalmiques comprenant de la brinzolamide Download PDF

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Publication number
WO2012053011A3
WO2012053011A3 PCT/IN2011/000720 IN2011000720W WO2012053011A3 WO 2012053011 A3 WO2012053011 A3 WO 2012053011A3 IN 2011000720 W IN2011000720 W IN 2011000720W WO 2012053011 A3 WO2012053011 A3 WO 2012053011A3
Authority
WO
WIPO (PCT)
Prior art keywords
brinzolamide
ophthalmic compositions
novel process
ophthalmic suspensions
beta
Prior art date
Application number
PCT/IN2011/000720
Other languages
English (en)
Other versions
WO2012053011A2 (fr
Inventor
Ashok Omray
Varsha Shashank Choudhary
Yogesh Sharad Bhide
Dinesh Yashawant Parsai
Original Assignee
Usv Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Limited filed Critical Usv Limited
Publication of WO2012053011A2 publication Critical patent/WO2012053011A2/fr
Publication of WO2012053011A3 publication Critical patent/WO2012053011A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un nouveau procédé de préparation de suspensions ophtalmiques d'un inhibiteur d'anhydrase carbonique tel que la brinzolamide. Le procédé se caractérise en ce qu'il ne nécessite pas l'autoclavage de l'ingrédient actif brinzolamide. L'invention concerne en outre des suspensions ophtalmiques contenant de la brinzolamide seule ou en association avec un bêta-bloquant préparé par ce nouveau procédé.
PCT/IN2011/000720 2010-10-18 2011-10-18 Compositions ophthalmiques comprenant de la brinzolamide WO2012053011A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2894MU2010 2010-10-18
IN2894/MUM/2010 2010-10-18

Publications (2)

Publication Number Publication Date
WO2012053011A2 WO2012053011A2 (fr) 2012-04-26
WO2012053011A3 true WO2012053011A3 (fr) 2012-10-04

Family

ID=45464055

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000720 WO2012053011A2 (fr) 2010-10-18 2011-10-18 Compositions ophthalmiques comprenant de la brinzolamide

Country Status (1)

Country Link
WO (1) WO2012053011A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150119386A1 (en) 2012-05-21 2015-04-30 Aurobindo Pharma Limited Process for preparing opthalmic suspension of brinzolamide
WO2014057499A1 (fr) 2012-10-11 2014-04-17 Indoco Remedies Limited Procédé de production d'une suspension ophtalmique stérile à base de la brinzolamide
US10463674B2 (en) 2013-11-08 2019-11-05 Sentiss Pharma Private Limited Process for manufacturing sterile ophthalmic pharmaceutical suspensions
US9820991B2 (en) * 2013-11-08 2017-11-21 Sentiss Pharma Private Limited Pharmaceutical composition comprising brinzolamide
PL407710A1 (pl) * 2014-03-28 2015-10-12 Instytut Farmaceutyczny Sposób wytwarzania preparatu kropli do oczu w postaci zawiesiny zawierającej brynzolamid i preparat wytworzony tym sposobem
JP6279395B2 (ja) * 2014-05-01 2018-02-14 東亜薬品株式会社 ブリンゾラミド懸濁性点眼液組成物の製造方法
CN106535943A (zh) 2014-07-11 2017-03-22 富士胶片株式会社 眼科用水性组合物
WO2022156371A1 (fr) * 2021-01-22 2022-07-28 成都瑞沐生物医药科技有限公司 Support ou substance auxiliaire de préparation ophtalmique, son procédé de préparation et son application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1985618A1 (fr) * 2007-04-27 2008-10-29 Duke Chem, S. A. Procédé de préparation de brinzolamide et intermédiaires correspondants
JP2010037327A (ja) * 2008-07-07 2010-02-18 Wakamoto Pharmaceut Co Ltd ブリンゾラミド水性組成物
WO2010103115A1 (fr) * 2009-03-13 2010-09-16 Azad Pharmaceutical Ingredients Ag Procédé de préparation de brinzolamide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153192A (en) 1990-04-09 1992-10-06 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
US5378703A (en) 1990-04-09 1995-01-03 Alcon Laboratories, Inc. Sulfonamides useful as carbonic anhydrase inhibitors
US6071904A (en) 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
WO2008062463A2 (fr) 2006-10-13 2008-05-29 Usv Limited Procédé perfectionné pour la préparation de (r)-(+)-4-(éthylamino)-3,4-dihydro-2-(3-méthoxypropyl)-2h-thiéno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxyde

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1985618A1 (fr) * 2007-04-27 2008-10-29 Duke Chem, S. A. Procédé de préparation de brinzolamide et intermédiaires correspondants
JP2010037327A (ja) * 2008-07-07 2010-02-18 Wakamoto Pharmaceut Co Ltd ブリンゾラミド水性組成物
WO2010103115A1 (fr) * 2009-03-13 2010-09-16 Azad Pharmaceutical Ingredients Ag Procédé de préparation de brinzolamide

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"GUIDE TO INSPECTIONS OF STERILE DRUG SUBSTANCE MANUFACTURERS", 30 April 2009 (2009-04-30), XP002679029, Retrieved from the Internet <URL:http://www.fda.gov/ICECI/Inspections/InspectionGuides/ucm074930.htm> [retrieved on 20120629] *
AKRAM MUHAMMAD ET AL: "Development of new ophthalmic suspension prednisolone acetate 1%.", PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 23, no. 2, April 2010 (2010-04-01), pages 149 - 154, XP002679030, ISSN: 1011-601X *
ANONYMOUS: "Australian Public Assessment Report for Brinzolamide/ Timolol Maleate", February 2010 (2010-02-01), pages 1 - 47, XP002679031, Retrieved from the Internet <URL:http://www.tga.gov.au/pdf/auspar/auspar-timolol.pdf> [retrieved on 20120702] *
RAJESH M. PATEL *: "PARENTERAL SUSPENSION: AN OVERVIEW", INTERNATIONAL JOURNAL OF CURRENT PHARMACEUTICAL RESEARCH, vol. 2, no. 3, 1 January 2010 (2010-01-01), pages 4 - 13, XP055031426, ISSN: 0975-7066, Retrieved from the Internet <URL:http://dfpcorec-p/wf/web/citenpl/citenpl.html?_url=http%3A%2F%2Fwww.ijcpr.org%2FIssues%2FVol2Issue3%2F195.pdf> *

Also Published As

Publication number Publication date
WO2012053011A2 (fr) 2012-04-26

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