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WO2011004360A1 - Dispositifs de transfert de fluide permettant de remplir une cartouche avec une dose de médicament liquide - Google Patents

Dispositifs de transfert de fluide permettant de remplir une cartouche avec une dose de médicament liquide Download PDF

Info

Publication number
WO2011004360A1
WO2011004360A1 PCT/IL2010/000530 IL2010000530W WO2011004360A1 WO 2011004360 A1 WO2011004360 A1 WO 2011004360A1 IL 2010000530 W IL2010000530 W IL 2010000530W WO 2011004360 A1 WO2011004360 A1 WO 2011004360A1
Authority
WO
WIPO (PCT)
Prior art keywords
cartridge
vial
drug dosage
liquid drug
port
Prior art date
Application number
PCT/IL2010/000530
Other languages
English (en)
Inventor
Moshe Barkan
Niv Ben Shalom
Original Assignee
Medimop Medical Projects Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimop Medical Projects Ltd filed Critical Medimop Medical Projects Ltd
Publication of WO2011004360A1 publication Critical patent/WO2011004360A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/062—Carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means

Definitions

  • the invention relates to fluid transfer devices for filling a cartridge with a liquid drug dosage.
  • Auto-injectors for self-administration of liquid drugs such as insulin typically employ so-called carpules or cartridges including an open ended tube hermetically sealed by a rubber septum at a leading end and a slidable seal at an opposite trailing end.
  • Cartridges can contain a single liquid drug dosage or a multiple liquid drug dosage.
  • Home users are typically supplied with pre- filled cartridges but may be supplied with empty cartridges requiring a manual cartridge filling procedure for filling same with a liquid drug dosage.
  • the manual cartridge filling procedure includes the following steps: A user prepares a syringe with a liquid drug dosage, mounts a needle on the syringe, punctures the cartridge's rubber septum and injects the liquid drug dosage into the cartridge. The user may have an additional step of reconstituting the liquid drug dosage from a powdered medicament.
  • WO 2007/105221 illustrates and describes fluid transfer devices for use with syringes and cartridges for assisting a manual cartridge filling procedure.
  • the fluid transfer devices include a syringe port and a cartridge port for correspondingly slidingly receiving a syringe and a cartridge.
  • WO 2007/105221 's Figures IA, 2, 3 and 4 show fluid transfer devices including a double ended main body having a cartridge port for telescopically receiving a cartridge and a syringe port for receiving a syringe.
  • WO 2007/105221 's Figures IB and 5 show a fluid transfer device similar in construction and operation to the fluid control devices with rotationally detachable vial adapters as illustrated and described in US Patent No. 6,238,372 to Zinger et al.'s Figures 11 to 15.
  • the cartridge ports preferably includes a primary puncturing member and a secondary puncturing member for correspondingly puncturing a cartridge's rubber septum offset from its center for fluid transfer purposes between a syringe and a cartridge, and venting purposes.
  • the fluid transfer devices are preferably used with stopping devices for preventing ejection of a cartridge's seal during a manual cartridge filling procedure.
  • the present invention is directed toward fluid transfer devices for use in manual cartridge filling procedures for filling cartridges with liquid drug dosages from medicament containing vials.
  • the present invention is based on provisioning an otherwise conventional cartridge including a slidable seal with a releasable attachment arrangement and a manual push rod for releasable attachment to the slidable seal for enabling manual displacement of same for aspirating a liquid drug dosage from a vial thereinto.
  • Suitable releasable attachment arrangements include inter alia a screw thread arrangement, and the like.
  • the cartridges can be employed for aspirating either a liquid drug dosage from a liquid medicament containing vial or a reconstituted liquid drug dosage from a powder medicament containing vial whose contents have undergone reconstitution.
  • the fluid transfer devices of the present invention include a double ended main body having a cartridge port for slidingly receiving a cartridge leading end and either a vial port for snap fitting onto a vial or a male connector for sealed fluid engagement with a conventional vial adapter including a female connector.
  • Suitable vial adapters are illustrated and described in US Design Patent No. 427,308 to Zinger et al. and are commercially available from Medimop Medical Projects Ltd., Ra'anana, Israel.
  • the male connector is preferably a male Luer lock connector.
  • Cartridge ports necessarily enable convenient manual withdrawal of a cartridge for subsequent deployment in an auto-injector.
  • Cartridge ports can be provisioned with a cartridge snap fit arrangement for removable snap fitting onto a cartridge leading end.
  • the cartridge snap fit arrangement can be implemented by a slotted skirt with a plurality of flex members with inwardly directed ridges for telescopically snap fitting onto a cartridge's leading end.
  • Cartridges can be manually withdrawn from such cartridge snap fit arrangements by bearing a cartridge against the inwardly directed ridges of a slotted skirt's flex members to temporarily slightly outward flex them until a cartridge passes beyond their inwardly directed ridges.
  • cartridge ports can be implemented with a finger operated cartridge snap fit arrangement for releasing a cartridge whereby the cartridge can be freely slidingly withdrawn.
  • Fig. 1 is a pictorial representation of a kit including a cartridge, a push rod, a vial and a first preferred embodiment of a fluid transfer device with a cartridge port and a vial port for direct fluid communication between the cartridge and the vial;
  • Fig. 2 is a longitudinal cross section of an assemblage of Figure l's fluid transfer device, cartridge and vial;
  • Figs. 3A to 3E show the steps of a manual cartridge filling procedure for filling a cartridge with a reconstituted liquid drug dosage
  • Fig. 4 is a longitudinal cross section of a second preferred embodiment of a fluid transfer device with a cartridge port and a male connector for use with a conventional vial adapter with a female connector for direct fluid communication between a cartridge and a vial;
  • Fig. 5 is a pictorial representation of an alternative implementation of Figure 4's fluid transfer device including a finger operated cartridge snap fit arrangement
  • Fig. 6 is a longitudinal cross section of an assemblage of Figure 5's fluid transfer device, cartridge and vial along line A-A in Figure 5.
  • Figures 1 and 2 show a kit 5 including a pre-filled diluent containing cartridge 10, a powder medicament containing vial 30 and a fluid transfer device 40 for use in a manual cartridge filling procedure for filling the cartridge 10 with a reconstituted liquid drug dosage.
  • the cartridge 10 includes an open ended tube 11 having a longitudinal axis 12, a small diameter cartridge leading end 13, an intermediate neck 14 and a wide diameter cartridge trailing end 16.
  • the cartridge leading end 13 is hermetically sealed by a rubber cartridge septum 17 capped by a metal band 18 leaving a small exposed circular rubber surface 19 of between about 2mm and 3mm in diameter.
  • the trailing end 16 is hermetically sealed by a slidable seal 21.
  • the slidable seal 21 has an exposed trailing surface 22 formed with a screw thread blind bore 23 for screw thread attachment with a push rod 24 having a screw threaded leading end 26.
  • the cartridge 10 contains diluent 27.
  • the vial 30 includes an open topped bottle 31 having a longitudinal axis 32 and hermetically sealed by a rubber vial stopper 33 capped by a metal band 34.
  • the vial 30 contains a powder drug dosage 36 requiring reconstitution by the cartridge's diluent contents 27.
  • the vial's powder drug contents 36 are typically stored under vacuum.
  • the vial 30 can contain a liquid drug dosage suitable for direct transfer to an empty cartridge.
  • the fluid transfer device 40 has a longitudinal axis 41 and includes a double ended main body 42 having a cartridge port 43 for slidingly receiving the cartridge leading end 13 therein and a vial port 44 for telescopically snap fitting onto the vial 30.
  • the cartridge port 43 includes a cartridge snap fit arrangement 45 implemented in the form of a slotted skirt 46 with a plurality of flex members 47 having inwardly directed ridges 48 for telescopically removably snap fitting onto the cartridge leading end 13 and a puncturing member 49 for puncturing the cartridge septum 17.
  • the puncturing member 49 is preferably constituted by a metal needle having an outer diameter of, say, about 0.5mm.
  • the vial port 44 includes a slotted skirt 51 with a plurality of flex members 52 having inwardly directed ridges 53 and a hollow cannula 54 for puncturing the vial septum 33.
  • the puncturing member 49 and the cannula 54 are co-axial with the fluid transfer device's longitudinal axis 41 and enable direct fluid communication between a cartridge 10 and a vial 30 in an assemblage 56 of the fluid transfer device 40, the cartridge 10 and the vial 30
  • Figures 3A to 3E show the steps of a manual cartridge filling procedure using the kit 5 to reconstitute a liquid drug dosage to fill the cartridge with same as follows:
  • Figure 3A shows a user screw threading the push rod 24 into a pre-filled cartridge 10 depicted by arrow A, inserting the cartridge 10 into the cartridge port 43 depicted by arrow B and mounting the vial port 44 on the vial 30 depicted by arrow C to form the assemblage 56.
  • Figure 3B shows the vial 30's vacuum drawing the cartridge's diluent into the vial 30 as depicted by arrow D for reconstituting a liquid drug 57 in the vial.
  • a user may additionally depress the push rod 24 to assist the vacuum to transfer the diluent to the vial 30.
  • Figure 3C shows the user inverting the assemblage 56 and aspirating the reconstituted liquid drug 57 into the cartridge 10 depicted by arrow E.
  • Figure 3D shows the user inverting the assemblage 56 into its original upright position, unscrewing the push rod 24 depicted by arrow F and detaching the cartridge 10 from the assemblage 56 depicted by arrow G such that the reconstituted liquid drug filled cartridge 10 is ready for use in an automatic pen (see Figure 3E).
  • Figure 4 shows a fluid transfer device 60 for use with a conventional vial adapter 70 with a female connector 71.
  • the fluid transfer device 60 has a similar construction as the fluid transfer device 40 and similar parts are likewise numbered.
  • the fluid transfer device 60 differs from the fluid transfer device 40 insofar the former 60 includes a male connector 61 for screw thread fluid engagement on the female connector 71 for enabling fluid communication between a cartridge 10 inserted into the fluid transfer device 60's cartridge port 43 and a vial 30 inserted into the vial adapter 70.
  • the male and female connectors 61 and 71 are preferably Luer lock connectors.
  • Figures 5 and 6 show the fluid transfer device 60 with a cartridge port 43 implemented by an open ended cartridge holder 62 for slidingly receiving a cartridge 10 and a finger operated cartridge snap fit arrangement 63 for initially snap fitting onto a cartridge 10 on its sliding insertion into the cartridge holder 62 and enabling a user to manually release the cartridge 10 for enabling the cartridge 10 to be freely slidingly withdrawn from the cartridge holder 62.
  • the cartridge holder 62 is typically dimensioned such that a cartridge 10 can be inserted about midway along its length.
  • the cartridge holder 62 includes a pair of opposite support members 64 and the finger operated cartridge snap fit arrangement 63 includes a pair of opposite flex members 66 each having an outwardly directed finger operated member 67.
  • the flex members 66 each terminate in an inwardly directed ridge 68 toward the male connector 61 for snap fit insertion against a cartridge's neck 14 on sliding insertion of a cartridge 10 into the cartridge holder 62. Depression of the pair of opposite flex members 66 towards one another depicted by arrows H outwardly urges the inwardly directed ridges 68 depicted by arrows I thereby enabling a cartridge 10 to be freely withdrawn.
  • cartridge port 43 can be alternately implemented by the open ended cartridge holder 62 and the finger operated cartridge snap fit arrangement 63.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne des dispositifs de transfert de fluide destinés à être utilisés lors d'une procédure de remplissage de cartouche manuelle pour remplir une cartouche avec une dose de médicament liquide et concerne également des kits, des procédés et des cartouches associés. Les dispositifs de transfert de fluide comprennent un orifice de cartouche destiné à recevoir de manière coulissante une extrémité avant de cartouche et soit un orifice de flacon destiné à s'encliqueter sur un flacon soit un raccord mâle pour un contact fluidique étanche avec un adaptateur de flacon traditionnel comprenant un raccord femelle. La cartouche comprend un joint coulissant et une tige de poussée pour une fixation amovible au joint coulissant permettant le déplacement manuel du joint coulissant à des fins d'aspiration et d'injection.
PCT/IL2010/000530 2009-07-09 2010-07-01 Dispositifs de transfert de fluide permettant de remplir une cartouche avec une dose de médicament liquide WO2011004360A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL199767A IL199767A0 (en) 2009-07-09 2009-07-09 Medical device for use with cartridge and vial
IL199767 2009-07-09

Publications (1)

Publication Number Publication Date
WO2011004360A1 true WO2011004360A1 (fr) 2011-01-13

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Family Applications (1)

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PCT/IL2010/000530 WO2011004360A1 (fr) 2009-07-09 2010-07-01 Dispositifs de transfert de fluide permettant de remplir une cartouche avec une dose de médicament liquide

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IL (1) IL199767A0 (fr)
WO (1) WO2011004360A1 (fr)

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
WO2013150538A1 (fr) 2012-04-05 2013-10-10 Medimop Medical Projects Ltd Dispositifs de transfert de liquides comportant un orifice pour cartouche doté d'un agencement d'éjection de cartouche
EP2771047A1 (fr) * 2011-12-19 2014-09-03 Medimop Medical Projects Ltd Adaptateur de fiole à utiliser avec une seringue possédant un embout de seringue distal élargi
WO2015134777A1 (fr) * 2014-03-05 2015-09-11 Yukon Medical Llc Adaptateur de flacon de seringue de diluant pré-rempli
USD747472S1 (en) 2014-01-06 2016-01-12 Zoetis Services Llc Fluid transfer device
WO2016110838A1 (fr) * 2015-01-05 2016-07-14 Medimop Medical Projects Ltd Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte
USD769444S1 (en) 2012-06-28 2016-10-18 Yukon Medical, Llc Adapter device
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
WO2017212480A1 (fr) 2016-06-06 2017-12-14 Medimop Medical Projects Ltd Dispositifs de transfert de fluide pour remplir des cartouches de pompe à médicament avec un contenu médicamenteux liquide
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
CN111132647A (zh) * 2017-09-26 2020-05-08 科赫尔塑料机械制造有限公司 容器以及连接和制造装置
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
US10772798B2 (en) 2016-12-06 2020-09-15 West Pharma Services Il, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US10806671B2 (en) 2016-08-21 2020-10-20 West Pharma. Services IL, Ltd. Syringe assembly
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923782S1 (en) 2019-01-17 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
EP3687552A4 (fr) * 2017-09-28 2021-07-07 BioCeryx Technologies Inc. Dispositifs de transfert de sang et procédés associés
USD954253S1 (en) 2019-04-30 2022-06-07 West Pharma. Services IL, Ltd. Liquid transfer device
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
US20220267480A1 (en) * 2015-04-07 2022-08-25 Nissan Chemical Industries, Ltd. Method for preparing liquid medium composition, and preparation device and kit therefor
US11642285B2 (en) 2017-09-29 2023-05-09 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including twin vented female vial adapters
USD1010112S1 (en) 2021-07-03 2024-01-02 KAIRISH INNOTECH Private Ltd. Vial adapter with valve
US11918542B2 (en) 2019-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device
US12274670B2 (en) 2019-04-09 2025-04-15 West Pharma. Services IL, Ltd. Liquid transfer device with integrated syringe

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WO2007105221A1 (fr) 2006-03-16 2007-09-20 Medimop Medical Projects Ltd Dispositifs de transfert de fluide a des fins d'utilisation avec des cartouches
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DE1913926A1 (de) * 1969-03-19 1970-09-24 Hoechst Ag Zweikammerspritze
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WO2009112489A1 (fr) * 2008-03-10 2009-09-17 Süddeutsche Feinmechanik GmbH Dispositif de mélange

Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
EP2771047A1 (fr) * 2011-12-19 2014-09-03 Medimop Medical Projects Ltd Adaptateur de fiole à utiliser avec une seringue possédant un embout de seringue distal élargi
CN104185487A (zh) * 2011-12-19 2014-12-03 麦迪麦珀医疗工程有限公司 与具有加宽的远侧注射器端头的注射器一起使用的药水瓶转接器
WO2013150538A1 (fr) 2012-04-05 2013-10-10 Medimop Medical Projects Ltd Dispositifs de transfert de liquides comportant un orifice pour cartouche doté d'un agencement d'éjection de cartouche
CN104203195A (zh) * 2012-04-05 2014-12-10 麦迪麦珀医疗工程有限公司 具有带有套筒弹出装置的套筒端口的流体转移装置
USD769444S1 (en) 2012-06-28 2016-10-18 Yukon Medical, Llc Adapter device
US10299990B2 (en) 2012-08-26 2019-05-28 West Pharma. Services IL, Ltd. Liquid drug transfer devices
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
USD747472S1 (en) 2014-01-06 2016-01-12 Zoetis Services Llc Fluid transfer device
WO2015134777A1 (fr) * 2014-03-05 2015-09-11 Yukon Medical Llc Adaptateur de flacon de seringue de diluant pré-rempli
EP3113812A4 (fr) * 2014-03-05 2018-03-07 Yukon Medical, LLC Adaptateur de flacon de seringue de diluant pré-rempli
US10813837B2 (en) 2014-03-05 2020-10-27 Yukon Medical, Llc Pre-filled diluent syringe vial adapter
EP3581225A1 (fr) * 2014-03-05 2019-12-18 Yukon Medical, LLC Adaptateur de flacon de seringue de diluant préremplie
CN108601706A (zh) * 2015-01-05 2018-09-28 麦迪麦珀医疗工程有限公司 具有用于保证正确使用的快速释放药瓶转接器的药瓶转接器组件
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
WO2016110838A1 (fr) * 2015-01-05 2016-07-14 Medimop Medical Projects Ltd Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte
US20220267480A1 (en) * 2015-04-07 2022-08-25 Nissan Chemical Industries, Ltd. Method for preparing liquid medium composition, and preparation device and kit therefor
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
JP2019517352A (ja) * 2016-06-06 2019-06-24 ウエスト・ファーマ．サービシーズ・イスラエル，リミテッド 液剤内容物を有する薬剤ポンプカートリッジを充填するための流体移送デバイス
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