WO2011098819A1 - Dietary supplement composition - Google Patents
Dietary supplement composition Download PDFInfo
- Publication number
- WO2011098819A1 WO2011098819A1 PCT/GB2011/050248 GB2011050248W WO2011098819A1 WO 2011098819 A1 WO2011098819 A1 WO 2011098819A1 GB 2011050248 W GB2011050248 W GB 2011050248W WO 2011098819 A1 WO2011098819 A1 WO 2011098819A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dietary supplement
- supplement composition
- weight
- curcumin
- piperine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- This invention relates to a dietary supplement composition for the human or animal body, and in particular to a dietary supplement composition comprising Moringa oleifera, Curcumin, and Piperine.
- Moringa oleifera is instrumental in the fight against global malnutrition. It is a complete multivitamin vegetable. It is rich in Vitamin A, C, Calcium, Protein, Potassium, Iron, Essential Amino Acids and Phytonutrients which aid the immune system. It provides nourishment to the eyes and brain, strengthens the cell structure of the body, and delivers powerful nutrition.
- Moringa oleifera is an edible tree found worldwide in the dry tropics, and is increasingly being used for nutritional supplementation. Its nutrient-dense leaves are high in protein quality, leading to its widespread use by doctors, healers, nutritionists and community leaders, to treat under-nutrition and a variety of illnesses. The adoption of M. oleifera continues to increase.
- MEMO 250 and 750 mg/kg, po
- Ocimum sanctum 100 mg/kg, po
- MEMO produced significant increase in adhesion of neutrophils, attenuation of cyclophosphamide-induced neutropenia and an increase in phagocytic index in carbon clearance assay. From the above results, it can be concluded that MEMO stimulate both cellular and humoral immune response. However, low dose of MEMO was found to be more effective than the high dose.
- Moringa oleifera Lam (Moringaceae) are also used by the Indians in their herbal medicine as a hypocholesterolennic agent in obese patients.
- the scientific basis for their use in hypercholesterolemia was therefore examined. It was found (Ghasi et al Journal of Ethnopharmacology. 2000 Jan;69(1):21-5) that administration of the crude leaf extract of Moringa oleifera along with high-fat diet decreased the high-fat diet-induced increases in serum, liver, and kidney cholesterol levels by 14.35% (1 15-103.2 mg/100 ml of serum), 6.40% (9.4-8.8 mg/g wet weight) and 1 1 .09% (1 .09-0.97 mg/g wet weight) respectively.
- Piperine extract of Piper longum
- 1 Milligram of Piperine increases the body's ability to absorb curcumin and some other nutrients by over 100% (Shoba et al Planta Medica. 1998 May; 64(4):353-6 or Atal et al J Pharmacology and Experimental Therapeutics. 1985 Jan;232(1 ):258-62).
- a dietary supplement composition comprising Moringa oleifera, Curcumin and Piperine.
- the proportion of the ingredients that make up the dietary supplement composition of the present invention may be as follows:
- the proportion of the ingredients that make up the dietary supplement composition of the present invention may also be as follows:
- the dietary supplement composition may further comprise a stabiliser.
- the preservative may comprise about 2% by weight of Methyl Paraben and/or about 2% by weight of Proply Paraben.
- a dietary supplement composition comprising:
- the dietary supplement composition may further comprise a stabiliser.
- a stabiliser This may comprise at least Methyl Paraben, which may be about 10mg in weight and/or Propyl Paraben, which may be about 10mg in weight.
- the dietary supplement composition may comprise 250mg Moringa oleifera, 240mg Curcumin, 10mg Piperine, 10mg Methyl Paraben and 10mg Propyl Paraben.
- a tablet or capsule containing the dietary supplement composition according to this aspect of the present invention may have a weight that does not exceed about 700mg.
- the fornnulation may be adjusted to increase the potency and effect of certain ingredients, depending on the desired effect.
- the Piperine, Curcumin and Moringa oleifera help fight malnutrition, keep the body in its optimum form, while retaining all the medical benefits of a combination of PiCur, which is a food supplement with an ORAC (Oxygen Radical Absorbance Capacity) value of 159,000 and is available from The GlobaLeader Inc, Philippines.
- ORAC Oxygen Radical Absorbance Capacity
- Curcumin extract of Curcuma longa
- Curcumin and Piperine dry extracts are processed separately using known pulverization, extraction, evaporation, and crystallization techniques.
- Blumea balsamifera and Lagerstoemia speciosa dry extracts are processed separately using known pulverization and extraction techniques.
- the resulting powder extracts are then blended in the designated proportion and encapsulated using known techniques.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A dietary supplement composition comprising Moringa oleifera, Curcumin and Piperine. In one aspect of the invention the dietary supplement composition comprises between about 48%to about 58%by weight of Moringa oleifera, between about 37%to about 47%by weight of Curcumin, and between about 2% to about 4%by weight of Piperine. According to a another aspect of the invention the dietary supplement composition comprises between about 250mg to about 375mg Moringa oleifera, between about 200mg to about 250mg of Curcumin, and between about 10mg to about 20mg of Piperine.
Description
DIETARY SUPPLEMENT COMPOSITION
[0001] This invention relates to a dietary supplement composition for the human or animal body, and in particular to a dietary supplement composition comprising Moringa oleifera, Curcumin, and Piperine.
[0002] Moringa oleifera is instrumental in the fight against global malnutrition. It is a complete multivitamin vegetable. It is rich in Vitamin A, C, Calcium, Protein, Potassium, Iron, Essential Amino Acids and Phytonutrients which aid the immune system. It provides nourishment to the eyes and brain, strengthens the cell structure of the body, and delivers powerful nutrition.
[0003] Moringa oleifera is an edible tree found worldwide in the dry tropics, and is increasingly being used for nutritional supplementation. Its nutrient-dense leaves are high in protein quality, leading to its widespread use by doctors, healers, nutritionists and community leaders, to treat under-nutrition and a variety of illnesses. The adoption of M. oleifera continues to increase.
[0004]A study was conducted to investigate the immunomodulatory action of methanol ic extract of Moringa oleifera (MEMO) in an experimental model of immunity (Sudha et al Indian Journal of Physiology and Pharmacology. 2010 Apr- Jun;54(2):133-40). The cellular immunity was evaluated using neutrophil adhesion test, cyclophosphamide induced neutropenia and carbon clearance assay, whereas, humoral immunity was tested by mice lethality test, serum immunoglobulin estimation and indirect haemagglutination assay in animals. Administration of MEMO (250 and 750 mg/kg, po) and Ocimum sanctum (100 mg/kg, po) significantly increased the levels of serum immunoglobulins and also prevented the mortality induced by bovine Pasteurella multocida in mice. They also increased significantly the circulating antibody titre in indirect haemagglunation test. Moreover, MEMO produced significant increase in adhesion of neutrophils, attenuation of cyclophosphamide-induced neutropenia and an increase in phagocytic index in carbon clearance assay. From the above
results, it can be concluded that MEMO stimulate both cellular and humoral immune response. However, low dose of MEMO was found to be more effective than the high dose. [0005] The leaves of Moringa oleifera Lam (Moringaceae) are also used by the Indians in their herbal medicine as a hypocholesterolennic agent in obese patients. The scientific basis for their use in hypercholesterolemia was therefore examined. It was found (Ghasi et al Journal of Ethnopharmacology. 2000 Jan;69(1):21-5) that administration of the crude leaf extract of Moringa oleifera along with high-fat diet decreased the high-fat diet-induced increases in serum, liver, and kidney cholesterol levels by 14.35% (1 15-103.2 mg/100 ml of serum), 6.40% (9.4-8.8 mg/g wet weight) and 1 1 .09% (1 .09-0.97 mg/g wet weight) respectively. The effect on the serum cholesterol was statistically significant. No significant effect on serum total protein was observed. However, the crude extract increased serum albumin by 15.22% (46-53 g/l). This value was also found to be statistically significant. It was concluded that the leaves of Moringa oleifera have definite hypocholesterolennic activity and that there is valid pharmacological basis for employing them for this purpose. [0006]Curcumin (extract of Curcuma longa) is backed by over 3,000 clinical studies conducted worldwide (for example the review article Aggarwal et al in Advances in Experimental Medicine and Biology 2007;595:1 -75). Curcumin is beneficial in over 100 medical conditions. [0007] Piperine (extract of Piper longum) is a bio-availability enhancer. 1 Milligram of Piperine increases the body's ability to absorb curcumin and some other nutrients by over 100% (Shoba et al Planta Medica. 1998 May; 64(4):353-6 or Atal et al J Pharmacology and Experimental Therapeutics. 1985 Jan;232(1 ):258-62).
[0008] Therefore, according to the present invention there is provided a dietary supplement composition comprising Moringa oleifera, Curcumin and Piperine.
[0009]The proportion of the ingredients that make up the dietary supplement composition of the present invention may be as follows:
- between about 48% to about 58% by weight of Moringa oleifera;
- between about 37% to about 47% by weight of Curcumin; and
- between about 2% to about 4% by weight of Piperine.
[0010]The proportion of the ingredients that make up the dietary supplement composition of the present invention may also be as follows:
- about 48% by weight of Moringa oleifera;
- about 46% by weight of Curcumin; and
- about 2% by weight of Piperine.
[0011]The dietary supplement composition may further comprise a stabiliser. The preservative may comprise about 2% by weight of Methyl Paraben and/or about 2% by weight of Proply Paraben.
[0012] According to a further aspect of the present invention there is provided a dietary supplement composition comprising:
- between about 250mg to about 375mg Moringa oleifera;
- between about 200mg to about 250mg of Curcumin; and
- between about 10mg and about 20mg of Piperine.
[0013]The dietary supplement composition may further comprise a stabiliser. This may comprise at least Methyl Paraben, which may be about 10mg in weight and/or Propyl Paraben, which may be about 10mg in weight.
[0014]The dietary supplement composition may comprise 250mg Moringa oleifera, 240mg Curcumin, 10mg Piperine, 10mg Methyl Paraben and 10mg Propyl Paraben.
[0015] A tablet or capsule containing the dietary supplement composition according to this aspect of the present invention may have a weight that does not exceed about 700mg.
[0016] The fornnulation may be adjusted to increase the potency and effect of certain ingredients, depending on the desired effect. [0017] In combination, the Piperine, Curcumin and Moringa oleifera help fight malnutrition, keep the body in its optimum form, while retaining all the medical benefits of a combination of PiCur, which is a food supplement with an ORAC (Oxygen Radical Absorbance Capacity) value of 159,000 and is available from The GlobaLeader Inc, Philippines.
[0018] At least one example of the present invention will now be described, by way of example only.
[0019] Example 1
Composition - Weight
Moringa oleifera
Curcumin (extract of Curcuma longa)
Piperine (extract of Piper longum)
Methyl Paraben
Propyl Paraben
Method
Curcumin and Piperine dry extracts are processed separately using known pulverization, extraction, evaporation, and crystallization techniques.
Blumea balsamifera and Lagerstoemia speciosa dry extracts are processed separately using known pulverization and extraction techniques.
The resulting powder extracts are then blended in the designated proportion and encapsulated using known techniques.
Claims
1 . A dietary supplement composition comprising Moringa oleifera, Curcumin and Piperine.
2. A dietary supplement composition according to Claim 1 comprising:
- between about 48% to about 58% by weight of Moringa oleifera;
- between about 37% to about 47% by weight of Curcumin; and
- between about 2% to about 4% by weight of Piperine.
3. A dietary supplement composition according to Claim 1 or Claim 2, comprising:
- about 48% by weight of Moringa oleifera;
- about 46% by weight of Curcumin; and
- about 2% by weight of Piperine.
4. A dietary supplement composition as claimed in any of Claims 1 to 3, further comprising a stabiliser.
5. A dietary supplement composition as claimed in Claim 4, wherein the preservative comprises about 2% by weight of Methyl Paraben.
6. A dietary supplement composition as claimed in Claim 4 or Claim 5, wherein the preservative comprises about 2% by weight of Propyl Paraben.
7. A dietary supplement composition as claimed in Claim 1 comprising:
- between about 250mg to about 375mg Moringa oleifera;
- between about 200mg to about 250mg of Curcumin; and
- between about 10mg to about 20mg of Piperine.
8. A dietary supplement composition as claimed in Claim 7, further comprising a preservative.
9. A dietary supplement composition as claimed in Claim 8, wherein the preservative comprises about 10mg of Methyl Paraben.
10. A dietary supplement composition as claimed in Claim 8 or Claim 9, wherein the preservative comprises about 10mg of Propyl Paraben.
1 1 . A dietary supplement composition as claimed in any of Claims 7 to 10, wherein the composition comprises 250mg of Moringa oleifera, 240mg of Curcumin, 10mg of Piperine, 10mg of Methyl Paraben and 10mg of Propyl Paraben.
12. A dietary supplement composition as claimed in any of Claims 5 to 9, wherein the total weight of the composition does not exceed about 700mg.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1002318.2 | 2010-02-11 | ||
| GBGB1002318.2A GB201002318D0 (en) | 2010-02-11 | 2010-02-11 | Dietary supplement composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2011098819A1 true WO2011098819A1 (en) | 2011-08-18 |
Family
ID=42110562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/GB2011/050248 WO2011098819A1 (en) | 2010-02-11 | 2011-02-10 | Dietary supplement composition |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB201002318D0 (en) |
| WO (1) | WO2011098819A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2654868C1 (en) * | 2017-03-10 | 2018-05-23 | Сергей Иванович Корнилов | Nutritional composition |
| KR20180089258A (en) * | 2017-01-31 | 2018-08-08 | 순천제일대학산학협력단 | Its Manufacturing method and Manufacturing for Pill using Moringa(Moringa oleifera) by Fermentation |
| CN110897157A (en) * | 2019-11-26 | 2020-03-24 | 纳图纽万达尼曼拉股份有限公司 | Health-care preparation, preparation process and application |
| WO2021053518A1 (en) * | 2019-09-17 | 2021-03-25 | Basilianus Basuki Nugroho Edward | A method of snake fish extraction |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744161A (en) * | 1995-02-24 | 1998-04-28 | Sabinsa Corporation | Use of piperine as a bioavailability enhancer |
| US20100112101A1 (en) * | 2008-05-06 | 2010-05-06 | Laila Impex | Bio-availability/bio-efficacy enhancing activity of stevia rebaudiana and extracts and fractions and compounds thereof |
-
2010
- 2010-02-11 GB GBGB1002318.2A patent/GB201002318D0/en not_active Ceased
-
2011
- 2011-02-10 WO PCT/GB2011/050248 patent/WO2011098819A1/en active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744161A (en) * | 1995-02-24 | 1998-04-28 | Sabinsa Corporation | Use of piperine as a bioavailability enhancer |
| US20100112101A1 (en) * | 2008-05-06 | 2010-05-06 | Laila Impex | Bio-availability/bio-efficacy enhancing activity of stevia rebaudiana and extracts and fractions and compounds thereof |
Non-Patent Citations (13)
| Title |
|---|
| AGGARWAL ET AL., ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 595, 2007, pages 1 - 75 |
| ANONYMOUS: "Curcumin", WIKIPEDIA, THE FREE ENCYCLOPEDIA, 11 January 2009 (2009-01-11), pages 10PP, XP002634388, Retrieved from the Internet <URL:http://en.wikipedia.org/wiki/Curcumin> [retrieved on 20110414] * |
| ANONYMOUS: "Moringa oleifera", WIKIPEDIA, THE FREE ENCYCLOPEDIA, 8 January 2009 (2009-01-08), XP002634846, Retrieved from the Internet <URL:http://en.wikipedia.org/wiki/Moringa_oleifera> [retrieved on 20110428] * |
| ANONYMOUS: "MoringaCurPlus", BIMBYBAG, 19 May 2010 (2010-05-19), XP002634848, Retrieved from the Internet <URL:http://bimbybag.multiply.com/photos/album/36/MoringaCur_Plus> [retrieved on 20110429] * |
| ANONYMOUS: "PiCur", BIMBYBAG, 19 May 2010 (2010-05-19), XP002634392, Retrieved from the Internet <URL:http://bimbybag.multiply.com/photos/album/37/PiCur> [retrieved on 20110414] * |
| ANONYMOUS: "Piperine", WIKIPEDIA, THE FREE ENCYCLOPEDIA, 8 February 2009 (2009-02-08), XP002634390, Retrieved from the Internet <URL:http://en.wikipedia.org/wiki/Piperine> [retrieved on 20110414] * |
| ANONYMOUS: "Turmeric", WIKIPEDIA, THE FREE ENCYCLOPEDIA, 12 November 2009 (2009-11-12), XP002634389, Retrieved from the Internet <URL:http://en.wikipedia.org/wiki/Turmeric> [retrieved on 20110414] * |
| ATAL ET AL., J PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 232, no. 1, January 1985 (1985-01-01), pages 258 - 62 |
| GHASI ET AL., JOURNAL OF ETHNOPHARMACOLOGY, vol. 69, no. 1, January 2000 (2000-01-01), pages 21 - 5 |
| GUIDO SHOBA: "Influence of Piperine on the pharmacokinetics of curcumin in animals and huan volunteers", THIEME EJOURNALS, 1998, XP002634391, Retrieved from the Internet <URL:https://www.thieme-connect.de/DOI/DOI?10.1055/s-2006-957450> [retrieved on 20110426] * |
| PATTY DONOVAN: "Moringa oleifera: the miracle tree", NATURAL NEWS, 20 November 2007 (2007-11-20), XP002634847, Retrieved from the Internet <URL:http://www.naturalnews.com/022272.html> [retrieved on 20110428] * |
| SHOBA ET AL., PLANTA MEDICA, vol. 64, no. 4, May 1998 (1998-05-01), pages 353 - 6 |
| SUDHA ET AL., INDIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, vol. 54, no. 2, April 2010 (2010-04-01), pages 133 - 40 |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180089258A (en) * | 2017-01-31 | 2018-08-08 | 순천제일대학산학협력단 | Its Manufacturing method and Manufacturing for Pill using Moringa(Moringa oleifera) by Fermentation |
| KR102228199B1 (en) | 2017-01-31 | 2021-03-16 | 순천제일대학산학협력단 | Its Manufacturing method and Manufacturing for Pill using Moringa(Moringa oleifera) by Fermentation |
| RU2654868C1 (en) * | 2017-03-10 | 2018-05-23 | Сергей Иванович Корнилов | Nutritional composition |
| WO2021053518A1 (en) * | 2019-09-17 | 2021-03-25 | Basilianus Basuki Nugroho Edward | A method of snake fish extraction |
| CN110897157A (en) * | 2019-11-26 | 2020-03-24 | 纳图纽万达尼曼拉股份有限公司 | Health-care preparation, preparation process and application |
Also Published As
| Publication number | Publication date |
|---|---|
| GB201002318D0 (en) | 2010-03-31 |
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