WO2011067105A1

WO2011067105A1 - Fragrancing process combining a topical fragrance with an oral fragrance; fragrancing kit

Info

Publication number: WO2011067105A1
Application number: PCT/EP2010/067560
Authority: WO
Inventors: Virginie Albelda; Isabelle Bara
Original assignee: L'oreal
Priority date: 2009-12-04
Filing date: 2010-11-16
Publication date: 2011-06-09
Also published as: BR112012013278A2; JP2013512867A; KR20120109541A; EP2506935A1; CN102725033A

Abstract

The invention relates to a fragrancing process that includes the following steps: (1) the direct application to human keratin materials or to clothing of a fragrancing composition (A) comprising, in a cosmetically acceptable medium, at least one fragrancing substance; the said composition producing a fragrance with a head note and/or a heart note and/or a base note; (2) the ingestion or placing in the mouth of at least one composition (B) comprising at least one edible fragrancing substance capable of producing an odour from within the body out to the human keratin materials; the said edible fragrancing substance being chosen such that the composition (B) produces a fragrance having at least one note in common with at least one of those of the fragrance produced by composition (A); the order of the steps not being critical, and the application of compositions (A) and (B) possibly being simultaneous or at different times. Composition (B) may comprise: a) at least one composition (Bi) comprising, in a support suitable for oral application, at least one edible fragrancing substance (1), which can, after ingestion or placing in the mouth, produce from within the body out to the human keratin materials a perfume whose diffusion reaches its maximum at a time of less than 4 hours 30 minutes, and b) at least one composition (B2) comprising, in a support suitable for oral application, at least one edible fragrancing substance (2) which can, after ingestion or placing in the mouth, produce from within the body out to the human keratin materials a perfume whose diffusion reaches its maximum at a time of greater than or equal to 4 hours 30 minutes.

Description

FRAGRA CING PROCESS COMBINING A TOPICAL FRAGRANCE WITH AN ORAL FRAGRANCE ; FRAGRANCING KIT

The invention relates to a fragrancing process that includes the following steps:

(1) the direct application to human keratin materials or to clothing of a fragrancing composition

(A) comprising, in a cosmetically acceptable medium, at least one fragrancing substance; the said composition producing a fragrance with a head note and/or a heart note and/or a base note;

(2) the ingestion of at least one composition (B) comprising, in a medium suitable for oral application, at least one edible fragrancing substance capable of producing an odour from within the body out to the human keratin materials; the said edible fragrancing substance being chosen such that the composition (B) produces a fragrance having at least one note in common with at least one of those of the fragrance produced by composition (A) ; the order of the steps not being critical, and the application of compositions (A) and

(B) possibly being simultaneous or at different times.

The invention also relates to a fragrancing kit or device containing at least two compartments, characterized in that it comprises:

- a first conditioning comprising composition (A) as defined previously;

- a second conditioning comprising composition (B) as defined previously.

Man has since time immemorial sought to fragrance himself and to fragrance the objects surrounding him or his environment, both to mask strong and/or unpleasant odours and to give a good odour.

It is known that a perfume is a combination of different odoriferous substances that evaporate at different periods. It is possible to classify a perfume according to its olfactory family, and to describe it as a function of the notes that appear during its use. These olfactory notes are differentiated into head notes (those associated with the first olfactory impression and which are the most volatile) , heart notes (which constitute the body of the perfume and remain for a few hours) and finally base notes (which persist for a long time after the perfume has vaporized and which may remain on clothing for months) . Certain perfumes may, however, have a different olfactory construction, namely they may have one or two of these notes .

It is common practice to incorporate perfume into a certain number of products or compositions, in particular cosmetic and dermatological compositions applied directly via the topical route onto keratin materials, in particular the skin. These products are generally in the form of eau fraiche, perfume or eau de toilette, eau de parfum, elixir or extract of parfum, aftershave lotion and eau de soin. However, the remanence and intensity of the fragrance in these formulations remain limited over time. They decrease substantially after a few hours. Moreover, the fragrance diffuses mainly at the area of application.

Products for improving or modifying the odour of the body after ingestion of particular edible fragrancing substances have appeared on the market in recent years. These products have the role either of limiting unpleasant body odour (deodorant type) or of subtly fragrancing the skin (fragrancing type) .

One of the first products that appeared on the market is a Brazilian product from 2004 (Fiber Sense) based on essence of coriander, which was presented as an anticholesterol medicament, but one of the side effects thereof was that of pleasantly fragrancing the skin from within.

Many products aimed at deodorizing the body also appear on the oral cosmetics market and contain chlorophyll derivatives such as chlorophylline . These products are sold for limiting unpleasant body odour. Such products are described especially in the documents JP 10245343 (Taisho Pharmaceutical Co.), WO 2004/10574 (Mitchell Kurk Lawrence, NY) and JP2002224203.

Products this time claiming "fragrancing" of human keratin materials via the ingestion of edible products containing edible fragrancing substances capable of diffusing from within the body an odour onto human keratin materials, in particular the skin, have also been observed on the Asiatic oral cosmetics market. These products are sold in the form of confectionery, drinks, chewing gums or gel capsules. They are especially described in Chinese patent CN 1217889 (Liu) disclosing products based on mint, vanillin, geraniol and vitamins for the purpose of fragrancing human bodily fluids.

The patent application WO 2006/129 876 from Kanebo

Foods Ltd also discloses ingestible cosmetic products, preferably sweets or chewing gums, comprising at least one polar compound and/or terpene that fragrances the body after ingestion with edible fragrancing molecules such as geraniol, linalool and citronellol. The company Kanabo has been selling since 2006 chewing gums under the trade name Fuwarinka for the purpose of fragrancing the skin from within (based on geraniol, essence of rose and lemon) . The company Wakasa sells gel capsules under the brand name "Sofia" based on essence of rose.

There is thus still a need to find novel fragrancing processes for substantially improving the olfactory yield produced by topical fragrancing formulations, especially the intensity and/or the remanence and for also fragrancing the body as a whole and uniformly.

The Applicant has discovered, surprisingly, that this objective can be achieved with a fragrancing process that includes the following steps:

(1) the direct application to human keratin materials or to clothing of a fragrancing composition (A) comprising, in a cosmetically acceptable medium, at least one fragrancing substance; the said composition producing a fragrance with a head note and/or a heart note and/or a base note;

(2) the ingestion or placing in the mouth of at least one composition (B) comprising, in a medium suitable for oral application, at least one edible fragrancing substance that can produce an odour from within the body out to the human keratin materials; the said edible fragrancing substance being chosen such that composition (B) produces a fragrance having at least one note in common with at least one of those of the fragrance produced by composition (A) ; the order of the steps not being critical and the application of compositions (A) and (B) possibly being simultaneous or at different times.

This discovery forms the basis of the invention.

(1) the direct application to human keratin materials or to clothing of a fragrancing composition (A) comprising, in a cosmetically acceptable medium, at least one fragrancing substance; the same composition producing a fragrance with a head note and/or a heart note and/or a base note;

The invention also relates to a fragrancing kit or device with at least two conditionings, characterized in that it comprises at least: - a first conditioning comprising composition (A) as defined previously;

- a second conditioning comprising composition (B) as defined previously.

The term "human keratin materials" means the skin

(of the face or body) , the lips, the scalp, the hair, the eyelashes, the eyebrows, the nails or mucous membranes .

The term "fragrancing substance" means any fragrance or aroma capable of giving off a pleasant odour .

The term "edible substance" means any non-toxic substance suitable for oral application, in the oral cavity and on the lips.

The term "cosmetically acceptable medium" means a non-toxic medium that may be applied directly to the skin (face, body and lips) , the scalp, the hair, the eyelashes, the eyebrows, the nails and mucous membranes .

The term "different times" means time intervals between the application of composition (A) and the application of composition (B) . The user may thus successively apply composition (A) and composition (B) , the order being irrelevant, after a few seconds or after several hours in the same day, especially within an interval ranging from 30 seconds to 12 hours.

The fragrancing composition (A) according to the invention is in aqueous or anhydrous form, or in liquid, pasty or solid form.

The fragrancing composition (A) according to the invention may constitute a composition for fragrancing, caring for or treating keratin materials, and is especially in the form of a fragrance, an eau de parfum or eau de toilette, an eau fraiche, an aftershave lotion, an eau de soin or a silicone-based or hydrosilicone-based care oil. It may also be in the form of a fragranced two-phase lotion (for example hydrophilic phase/hydrocarbon-based oil phase and/or silicone oil phase) . It may also be in the form of a gel, balm or concrete.

It may also be in the form of a fragranced milk or cream (oil-in-water emulsion, water-in-oil emulsion or multiple emulsion of the water-in-oil-in-water or oil- in-water-in-oil type) .

It may also be in the form of a powder such as fragranced talcs. It may also be in the form of a roll- on (ball) or of sticks.

The fragrancing composition (A) may be diffused from various systems such as sprays, aerosols or piezoelectric devices.

The fragrances as used in composition (A) are compositions especially containing the starting materials described in S. Arctander, Perfume and Flavor Chemicals (Edition 2003) and in "Flavor and Fragrance Materials - 1991", Allured Publishing Co. Wheaton, 111.

They may be natural products (essential oils, absolutes, resinoids, resins or concretes) and/or synthetic products (terpene or sesquiterpene hydrocarbons, alcohols, phenols, aldehydes, ketones, ethers, acids, esters, nitriles and peroxides, which are saturated or unsaturated, and aliphatic or cyclic) .

According to the definition given in international standard ISO 9235 and adopted by the Commission of the European Pharmacopoeia, an essential oil is an odoriferous product generally of complex composition, obtained from a botanically defined plant raw material, either by steam entrainment, or by dry distillation, or via an appropriate mechanical process without heating (cold pressing) . The essential oil is usually separated from the aqueous phase via a physical process that does not result in any significant change in the composition . Modes for obtaining essential oils

The choice of technique depends mainly on the starting material: its original state and its characteristics, its actual nature. The "essential oil/plant starting material" yield may be extremely variable depending on the plant: 15 ppm to more than 20%. This choice conditions the characteristics of the essential oil, in particular viscosity, colour, solubility, volatility, richness or poorness in certain constituents .

Steam entrainment Steam entrainment corresponds to vaporization in the presence of steam of a sparingly water-miscible substance. The starting material is placed in contact with boiling water or steam in an alambic. The steam entrains the essential oil vapour, which is condensed in the condenser and recovered as a liquid phase in a Florentine vase (or essence jar) where the essential oil is separated from the water by settling. The aqueous distillate that remains after the steam entrainment, once the separation of the essential oil has been performed, is known as the "aromatic water" or "hydrolate" or "distilled floral water".

Dry distillation The essential oil is obtained by distillation of woods, barks or roots, without addition of water or steam, in a closed chamber designed so that the liquid is recovered at the bottom. Cade oil is the best known example of a product obtained in this way.

Cold pressing

This production method applies only to citrus fruits (Citrus spp . ) via mechanical processes at room temperature. The principle of the method is as follows: the zests are torn into pieces and the contents of the secretory sacs that have been broken are recovered by a physical process. The standard process consists in exerting an abrasive action on the entire surface of the fruit under a stream of water. After removal of the solid waste, the essential oil is separated from the aqueous phase by centrifugation . The majority of industrial installations allow simultaneous or sequential recovery of the fruit juices and of the essential oil.

Physicochemical characteristics Essential oils are generally volatile and liquid at room temperature, which distinguishes them from "set" oils. They are more or less coloured and their density is generally less than that of water. They have a high refractive index and most of them deflect polarized light. They are liposoluble and soluble in the usual organic solvents, entrainable with steam, and very sparingly soluble in water.

Among the essential oils that may be used according to the invention, mention may be made of those obtained from plants belonging to the following botanical families:

Abietaceae or Pinaceae: conifers

Amaryllidaceae

Anacardiaceae

Anonaceae: ylang ylang

Apiaceae (for example umbelliferae) : dill, angelica, coriander, sea fennel, carrot, parsley

Araceae

Aristolochiaceae

Asteraceae: yarrow, artemisia, camomile, helichrysum

Betulaceae

Brassicaceae

Burseraceae: frankincense Caryophyllaceae

Canellaceae

Cesalpiniaceae : copaifera (copaiba balsam)

Chenopodaceae

Cistaceae: rock rose

Cyperaceae

Dipterocarpaceae

Ericaceae: gaultheria (wintergreen)

Euphorbiaceae

Fabaceae

Geraniaceae: geranium

Guttiferae

Hamamelidaceae

Hernandiaceae

Hypericaceae : St-John' s wort

Iridaceae

Juglandaceae

Lamiaceae: thyme, oregano, monarda, savory, basil, marjorams, mints, patchouli, lavenders, sages, catnip, rosemary, hyssop, balm

Lauraceae: ravensara, sweet bay, rosewood, cinnamon, litsea

Liliaceae: garlic

Magnoliaceae : magnolia

Malvaceae

Meliaceae

Monimiaceae

Moraceae: hemp, hop

Myricaceae

Myristicaceae : nutmeg

Myrtaceae: eucalyptus, tea tree, paperbark tree, cajuput, backhousia, clove, myrtle

Oleaceae

Piperaceae: pepper

Pittosporaceae

Poaceae: lemon balm, lemongrass, vetiver

Polygonaceae

Renonculaceae

Rosaceae: roses Rubiaceae

Rutaceae: all citrus plants

Salicaceae

Santalaceae: sandalwood

Saxifragaceae

Schisandraceae

Styracaceae: benjoin

Thymelaceae: agar wood

Tilliaceae

Valerianaceae : valerian, spikenard

Verbenaceae: lantana, verbena

Violaceae

Zingiberaceae : galangal, turmeric, cardamom, ginger

Zygophyllaceae .

Mention may especially be made of the essential oils extracted from flowers (lily, lavender, rose, jasmine, ylang ylang, neroli) , from stems and leaves (patchouli, geranium, petitgrain) , from fruit (coriander, aniseed, cumin, juniper) , from fruit peel (bergamot, lemon, orange) , from roots (angelica, celery, cardamom, iris, sweet flag, ginger) , from wood (pinewood, sandalwood, gaiac wood, pink cedar, camphor) , from grasses and gramineae (tarragon, rosemary, basil, lemongrass, sage, thyme) , from needles and branches (spruce, fir, pine, dwarf pine) and from resins and balms (galbanum, elemi, benjoin, myrrh, olibanum, opopanax) .

Examples of fragrancing substances are especially: geraniol, geranyl acetate, farnesol, borneol, bornyl acetate, linolool, linalyl acetate, linalyl propionate, linalyl butyrate, tetrahydrolinolool , citronellol, citronellyl acetate, citronellyl formate, citronellyl propionate, dihydromyrcenol , dihydromyrcenyl acetate, tetrahydromyrcenol, terpineol, terpinyl acetate, nopol, nopyl acetate, nerol, neryl acetate, 2-phenylethanol, 2-phenylethyl acetate, benzyl alcohol, benzyl acetate, benzyl salicylate, styrallyl acetate, benzyl benzoate, amyl salicylate, dimethylbenzylcarbinol, trichloro- methylphenylcarbinyl acetate, p-tert-butylcyclohexyl acetate, isononyl acetate, vetiveryl acetate, vetiverol, -hexylcinnamaldehyde, 2-methyl-3- (p-tert- butylphenyl ) propanal , 2-methyl-3- (p-isopropylphenyl ) - propanal, 3- (p-tert-butylphenyl ) propanal , 2,4- dimethylcyclohex-3-enylcarboxaldehyde, tricyclodecenyl acetate, tricyclodecenyl propionate, 4- (4-hydroxy-4- methylpentyl ) -3-cyclohexenecarboxaldehyde, 4- (4-methyl- 3-pentenyl) -3-cyclohexenecarboxaldehyde, 4-acetoxy-3- pentyltetrahydropyran, 3-carboxymethyl-2-pentylcyclo- pentane, 2-n-4-heptylcyclopentanone, 3-methyl-2-pentyl- 2-cyclopentenone, menthone, carvone, tagetone, geranylacetone, n-decanal, n-dodecanal, 9-decen-l-ol, phenoxyethyl isobutyrate, phenylacetaldehyde dimethyl acetal, phenylacetaldehyde diethyl acetal, geranonitrile, citronellonitrile, cedryl acetate, 3- isocamphylcyclohexanol , cedryl methyl ether, isolongifolanone, aubepinonitrile, aubepine, heliotropin, coumarin, eugenol, vanillin, diphenyl ether, citral, citronellal, hydroxycitronellal , damascone, ionones, methylionones , isomethylionones , solanone, irones, cis-3-hexenol and esters thereof, musk-indans, musk-tetralins , musk-isochromans , macrocyclic ketones, musk-macrolactones , ethylene brassylate, and mixtures thereof.

According to one preferred embodiment of the invention, a mixture of different fragrancing substances that generate in common a note that is pleasant to the user is used.

The fragrancing substances will preferably be chosen such that they produce notes (head, heart and base) in the following olfactory families:

- citrine,

- ambery,

- floral,

- spicy,

- woody,

- oriental,

- gourmand, - chypre,

- fougere,

- leathery.

The cosmetically acceptable medium of composition (A) in accordance with the present invention preferably contains for the liquid compositions at least one volatile alcohol and/or one volatile silicone oil and/or water. Preferentially, the medium of the composition contains water in an amount preferably ranging from 0.01% to 50% and more preferentially from 0.5% to 25% by weight relative to the total weight of the composition.

For the purposes of the invention, the term "volatile alcohol" means any compound containing at least one alcohol function that is capable of evaporating on contact with the skin or the keratin fibre in less than one hour, at room temperature and atmospheric pressure. The volatile alcohol is a volatile cosmetic compound, which is liquid at room temperature, especially having a non-zero vapour pressure, at room temperature and atmospheric pressure, especially a vapour pressure ranging from 0.13 Pa to 40 000 Pa (10^~3 to 300 mmHg) , in particular ranging from 1.3 Pa to 13 000 Pa (0.01 to 100 mmHg) and more particularly ranging from 1.3 Pa to 1300 Pa (0.01 to 10 mmHg) .

For the purposes of the invention, the term "oil" means a water-insoluble fatty substance that is liquid at room temperature and atmospheric pressure.

For the purposes of the invention, the term

"volatile silicone oil" means any silicone compound that is capable of evaporating on contact with the skin or the keratin fibre in less than one hour, at room temperature and atmospheric pressure. The volatile compound is a volatile cosmetic compound, which is liquid at room temperature, especially having a non^¬ zero vapour pressure, at room temperature and atmospheric pressure, especially a vapour pressure ranging from 0.13 Pa to 40 000 Pa (10^~3 to 300 mmHg), in particular ranging from 1.3 Pa to 13 000 Pa (0.01 to 100 mmHg) and more particularly ranging from 1.3 Pa to 1300 Pa (0.01 to 10 mmHg).

The volatile alcohols in accordance with the present invention are preferably chosen from C1-C5 lower monoalcohols , which may be chosen from methanol, ethanol, propanol, isopropanol, n-butanol, isobutanol and t-butanol and more particularly ethanol.

The volatile alcohol (s) are preferably present in amounts ranging from 40% to 80% and more preferentially in amounts ranging from 55% to 80% by weight relative to the total weight of the composition.

Examples of volatile silicone oils that may be mentioned include volatile linear or cyclic silicone oils, especially those with a viscosity ≤ 6 centistokes (6 x 10^~6 m²/s) and especially containing from 2 to 10 silicon atoms, these silicones optionally comprising alkyl or alkoxy groups containing from 1 to 22 carbon atoms. As volatile silicone oils that may be used in the invention, mention may be made especially of octamethylcyclotetrasiloxane, decamethylcyclopenta- siloxane, dodecamethylcyclohexasiloxane, heptamethyl- hexyltrisiloxane, heptamethyloctyltrisiloxane, hexa- methyldisiloxane, octamethyltrisiloxane, decamethyl- tetrasiloxane and dodecamethylpentasiloxane, and mixtures thereof.

The volatile silicone oil (s) are preferably present in concentrations ranging from 40% to 98.5% and preferably from 10% to 80% by weight relative to the total weight of the composition.

The topical fragrancing composition (A) according to the invention may be manufactured via the known processes generally used in the field of fragranced lotions .

Composition (A) of the invention may also comprise any additive usually used in the field of fragrances chosen especially from antioxidants, UV-screening agents, dyes that are soluble in the medium, emulsifiers, cosmetic or dermatological active agents, for instance emollients or softeners, for instance sweet almond oil, apricot kernel oil, moisturizers such as glycerol, calmatives such as -bisabolol, allantoin or aloe vera; vitamins, essential fatty acids, propellants, peptizers, fillers, nacres and glitter flakes, and mixtures thereof. When they are present in the composition of the invention, these additives may be present in an amount ranging from 0.001% to 10% and better still from 0.01% to 5% by weight relative to the total weight of the composition.

The topical fragrancing composition (A) according to the invention in lotion form may be conditioned in the form of bottles. It may also be applied in the form of fine particles by means of pressurization devices. The devices in accordance with the invention are well known to those skilled in the art and comprise non- aerosol pumps or "atomizers", aerosol containers comprising a propellant and aerosol pumps using compressed air as propellant. These devices are described in patents US 4 077 441 and US 4 850 517 (which form an integral part of the content of the description) .

Composition (A) conditioned as an aerosol in accordance with the invention generally contains conventional propellants, for instance dimethyl ether, isobutane, n-butane or propane.

The edible fragrancing substances present in composition (B) of the invention may be chosen from:

(i) those indicated the official list established by the European Council in the publication "Substances aromatisantes et sources naturelles de matieres aromatisantes

[Aromatizing substances and natural sources of aromatizing materials], vol. 1 - 4th edition, 1992, Maisonneuve" ;

(ii) those indicated in the FEMA/GRAS official lists published by the Food and Drug Administration (FDA) . Edible fragrancing substances that produce notes in the following families will preferably be chosen:

- citrine: essence of lemon, citronellol, citral, essence of mandarin, essence of grapefruit, - ambery: terpineol, menthol, linalyl acetate,

- floral,

(i) pink flowers: geraniol, essence of rose, linalool ,

(ii) white flowers: heliotropin,

- spicy: essence of coriander, pepper, cinnamon, cinnamaldehyde, eugenol,

- woody: cedar wood, sandalwood,

- oriental,

- gourmand: vanillin, ethylvanillin, ethylmaltol, - chypre,

- fougere,

- leathery.

According to the invention, the edible fragrancing substances are chosen such that composition (B) produces a fragrance having a note in common with at least one of those of the fragrance produced by composition (A) .

According to one particular form of the invention, a composition (A) that produces a fragrance having at least one head note and/or one heart note will be used and the edible fragrancing substance (s) will be chosen such that composition (B) produces a fragrance having at least the same head note and/or the same heart note as the fragrance produced by composition (A) .

The daily dose of the edible fragrancing molecules of the invention will preferably range from 10^~5 to 200 mg according to the nature of the substance and of the galenical form containing it, and more preferentially from 0.05 to 85 mg. This dose may be taken in a single intake or in several intakes throughout the day.

The compositions (B) of the invention containing the various edible fragrancing substances, independently of each other, may be in liquid or solid form. They may be applied directly via the oral or sublingual route (applied under the tongue until totally dissolved, by absorption through the mucosae of the tongue and the mouth) . They may be in the form of capsules, especially to be melted under the tongue, tablets; gel capsules; granules; bars; pastes, pellets for sucking, hard, soft or jellified sweets, or sugar- coated sweets; chewing gums; drinks; solutions intended to be incorporated into pastries (for example macaroons), confectionery, flavoured sugars; powders to be diluted in water at the time of use; products that may be applied sublingually .

The various presentation or administration forms may be prepared according to the usual methods, with standard excipients that are compatible with oral administration .

The compositions (B) of the invention may also comprise one or more additives suitable for oral application chosen, for example, from food colorants, preserving agents, antioxidants, texture agents such as thickeners or gelling agents, flavour enhancers, sweeteners, emulsifiers, acidifying agents and stabilizers.

Needless to say, a person skilled in the art will take care to select the optional additional additives and/or the amount thereof such that the advantageous properties of the composition according to the invention are not, or are not substantially, adversely affected by the envisaged addition.

The invention also relates to a fragrancing kit or device with at least two conditionings, characterized in that it comprises at least:

- a first conditioning comprising composition (A) as defined previously;

- a second conditioning comprising composition (B) as defined previously.

The fragrancing composition (A) applied topically or to clothing may be conditioned in a bottle, a pressurization device such as a pump-dispenser bottle or an aerosol, a device suited for a fragranced talc equipped, for example, with a grille or a suitable applicator, a tube in the case of fragranced milks or creams, or wipes.

The fragrancing composition (B) applied orally may be conditioned in a box or pill bottle, a flask or a bottle (in the case of drinks or mouthwashes) , a conditioning suited for gel capsules, chewing gums or tablets, blister packs, sachets, or in drinkable vials.

According to one particular form of the invention, the composition (B) applied orally may be an oral fragrancing agent containing at least two components, characterized in that it comprises:

a) at least one component ( Bi ) comprising, in a support suitable for oral application, at least one edible fragrancing substance (1) that can, after ingestion or placing in the mouth, produce from within the body out to the human keratin materials, a fragrance whose diffusion reaches its maximum at a time of less than 4 hours 30 minutes, and

b) at least one composition ( B₂ ) comprising, in a support suitable for oral application, at least one edible fragrancing substance (2) that can, after ingestion or placing in the mouth, produce from within the body out to the human keratin materials, a fragrance whose diffusion reaches its maximum at a time of greater than or equal to 4 hours 30 minutes; the order of ingestion of compositions ( Bi ) and ( B₂ ) being irrelevant; compositions ( Bi ) and ( B₂ ) possibly being conditioned separately or together in the same galenical form.

- a first conditioning comprising composition (A) as defined previously;

- a second conditioning comprising composition ( Bi ) as defined previously, - a third conditioning comprising composition (B₂) as defined previously.

The Applicant has surprisingly discovered, in the course of its extensive research, that this type of two-component fragrancing agent can, after ingestion, diffuse from within the body a fragrance onto human keratin materials, in particular the skin, whose intensity remains uniform, efficient and constant from 1 hour 30 minutes to 6 hours at least.

The edible fragrancing substances (1) and (2) in accordance with the invention are chosen from those that produce fragrances with notes (head, heart and base) in the following olfactory families:

- citrine,

- ambery,

- floral,

- spicy,

- woody,

- oriental,

- gourmand,

- chypre,

- fougere,

- leathery.

Among the edible fragrancing substances (1) that can, after ingestion, produce from within the body out to the human keratin materials a fragrance whose diffusion reaches its maximum at a time of less than 4 hours 30 minutes, mention may be made preferentially of:

essence of rose, citronellol, ethylvanillin, linalool, menthol, essence of pepper.

Among the edible fragrancing substances (2) that can, after ingestion, produce from within the body out to the human keratin materials a fragrance whose diffusion reaches its maximum at a time of greater than or equal to 4 hours 30 minutes, examples that may be mentioned include: geraniol, linalyl acetate, citral, essence of coriander, ethylmaltol, γ-undecalactone, terpineol, heliotropin .

Another particular subject of the invention consists of a process for fragrancing human keratin materials, which consists in simultaneously or separately ingesting:

a) at least one composition ( Bi ) comprising, in a support suitable for oral application, at least one edible fragrancing substance (1) chosen from essence of rose, citronellol, menthol and essence of pepper, and b) at least one composition ( B₂ ) comprising, in a support suitable for oral application, at least one edible fragrancing substance (2) chosen from geraniol, linalyl acetate, citral, essence of coriander, ethylmaltol, γ-undecalactone, terpineol and heliotropin;

the order of ingestion of compositions ( Bi ) and ( B₂ ) being irrelevant; compositions ( Bi ) and ( B₂ ) possibly being conditioned separately or together in the same galenical form.

The invention also relates to a fragrancing kit or device for human keratin materials containing at least two conditionings, characterized in that it comprises at least:

- a first conditioning comprising composition ( Bi ) as defined previously;

- a second conditioning comprising composition ( B₂ ) as defined previously.

The daily dose of the edible fragrancing molecules of the invention will preferably range from 10^~5 to 200 mg and more preferentially from 0.05 to 85 mg according to the nature of the substance and of the galenical form containing it. This dose may be taken in a single intake or in several intakes throughout the day .

Compositions ( Bi ) and ( B₂ ) of the invention containing the various edible fragrancing substances, independently of each other, may be in the form of capsules especially to be melted under the tongue, tablets; gel capsules; granules; bars; pastes, pellets for sucking, hard, soft or jellified sweets, or sugar- coated sweets; chewing gums; drinks; solutions intended to be incorporated into pastries (for example macaroons), confectionery, flavoured sugars; powders to be diluted in water at the time of use; products that may be applied sublingually (applied under the tongue until totally dissolved, by absorption through the mucosae of the tongue and the mouth) . They may be conditioned, for example, in a box or pill bottle, a flask or a bottle (in the case of drinks), conditionings suited for gel capsules or tablets, blister packs, sachets or drinkable vials; conditionings suitable for chewing gums.

The compositions or components (Bi) and (B₂) of the invention may also comprise one or more additives suitable for oral application chosen, for example, from food colorants, preserving agents, antioxidants, texture agents, thickeners or gelling agents, flavour enhancers, sweeteners, emulsifiers, acidifying agents and stabilizers.

The invention will now be described with reference to the following examples, which are given as nonlimiting illustrations.

EXAMPLES

Protocol of the efficacy tests and results: The efficacy tests are performed in comparison with ingestion of a "neutral" or placebo capsule, composed solely of a neutral oil and a sweetener.

Evaluation of the skin of the "ingesters" was performed by a panel of "sniffer" experts at different times: 1 hour 30 minutes, 3 hours, 4 hours 30 minutes and 6 hours .

For each molecule, ten ingesters were smelled by ten sniffers. As a result, each molecule was smelled 100 times.

The evaluation was made in the crook of the elbow, according to very precise test conditions: exclusion of smokers, absence of fragranced washing product, shower gel or softener during the test. Absence of perfume or fragranced cosmetic during the test.

Diet excluding spices or alcohol the day before and throughout the duration of the test.

The "intensity" note on a scale from 0 to 5 was thus evaluated at the various evaluation times.

A molecule will be said to be "effective" relative to the placebo when its evaluation score of the mean intensity at each time is greater than 3/5.

EXAMPLE 1 :

A Tresor eau de toilette from Lancome that produces a perfume with a head note: fruity-peach, a heart note: floral-rose, and a base note: ambery- vanilla, is applied to the skin at TO.

One capsule of each fragrancing substance is then ingested and is left to melt under the tongue for as long as possible:

capsule containing 2.75 mg of ethylmaltol

capsule containing 0.0055 mg of essence of rose capsule containing 1.65 mg of γ-undecalactone capsule containing 1.5 mg of ethylvanillin .

Identical support capsules based on fish gelatine are prepared according to the process described in patent application WO 03/045 166.

After 1 hour 30 minutes, a very pleasant floral rose flower and gourmand odour corresponding to the heart and base notes of the Tresor eau de toilette applied topically alone is obtained on the skin. After 6 hours, this same floral gourmand odour is still obtained on the skin with an intensity of greater than 3/5 according to the evaluation test mentioned above .

EXAMPLE 2 :

A masculine eau de toilette based on menthol, cinnamaldehyde, essence of pepper and terpinen-4-ol is applied to the skin at o. This eau de toilette produces a perfume having a head note: spicy, a heart note: fresh-ambery and a base note: woody.

capsule containing 5.5 mg of menthol

capsule containing 0.33 mg of cinnamaldehyde capsule containing 5.5 mg of essence of pepper capsule containing 0.0385 mg of terpinen-4-ol .

After 1 hour 30 minutes, a very pleasant spicy, fresh and woody odour, corresponding to the head, heart and base notes of the eau de toilette applied topically alone, is obtained on the skin.

After 6 hours, this same spicy, fresh and woody odour is still obtained on the skin with an intensity of greater than 3/5.

EXAMPLE 3 :

An eau de toilette based on cinnamaldehyde and geraniol producing a floral and fresh perfume is applied to the skin at T₀.

cinnamaldehyde capsule containing 0.33 mg geraniol capsule containing 0.055 mg.

After 1 hour 30 minutes, a very pleasant floral and fresh odour is obtained on the skin.

After 6 hours, the same floral and fresh odour is obtained on the skin with an intensity of greater than 3/5.

EXAMPLE 4: MULTI-COMPONENT ORAL FRAGRA CING AGENT

(B)

The following are ingested and left to melt under the tongue for as long as possible:

- 3 capsules each containing 0.055 mg of geraniol (maximum diffusion at 4 hours 30 minutes) ,

- 3 capsules each containing 2.75 mg of ethylmaltol (maximum diffusion at 4 hours 30 minutes) , - 3 capsules each containing 0.55 mg of linalyl acetate (maximum diffusion at 4 hours 30 minutes) ,

- 3 capsules each containing 0.55 mg of citronellol (maximum diffusion at 3 hours) .

All the capsules are based on fish gelatine and are prepared according to the process described in patent application WO 03/045 166.

For each molecule, ten ingesters were smelled by ten sniffers. As a result, each molecule was smelled 100 times. The evaluation was made in the crook of the elbow, according to very precise test conditions: exclusion of smokers, absence of washing product, fragranced shower gel or fragranced softener during the test. Absence of perfume or fragranced cosmetic product during the test.

Results

A pleasant perfume of constant intensity greater than 3/5 is obtained from 1 hour 30 minutes to 6 hours, with a floral-fresh and slightly gourmand character.

Claims

1. Fragrancing process, characterized in that it includes the following steps:

(1) the direct application to human keratin materials or to clothing of a fragrancing composition (A) comprising, in a cosmetically acceptable medium, at least one fragrancing substance; the said composition producing a perfume with a head note and/or a heart note and/or a base note in the following families:

citrine,

ambery,

floral ,

spicy,

woody,

gourmand,

chypre,

fougere,

leathery;

(2) the ingestion or placing in the mouth of at least one composition (B) comprising at least one edible fragrancing substance that can produce an odour from within the body out to the human keratin materials; the said edible fragrancing substance being chosen such that composition (B) produces a perfume having at least one note in common with those of the perfume produced by composition (A) in the following families :

citrine,

ambery,

floral ,

spicy,

woody,

gourmand,

chypre,

fougere,

leathery; the order of the steps being irrelevant and the application of compositions (A) and (B) possibly being simultaneous or at different times.

2. Process according to Claim 1, in which composition (A) produces a perfume with at least one head note and/or one heart note and in which the edible fragrancing substance (s) are chosen such that composition (B) produces a fragrance with at least the same head note and/or the same heart note as that of the perfume produced by composition (A) .

3. Process according to Claim 1, in which the fragrancing composition (A) is in the form of eau de toilette, eau de parfum, eau fraiche, aftershave lotion, eau de soin, silicone-based or hydrosilicone- based care oil, fragranced two-phase lotion; fragranced milk or cream; fragranced powder, gel, balm or concrete; roll-on (ball); sticks.

4. Process according to any one of Claims 1 to 3, in which composition (A) is conditioned in a pressurization device.

5. Process according to any one of Claims 1 to 4, in which composition (B) is in the form of capsules especially to be melted under the tongue, tablets; gel capsules; granules; bars; pastes, pellets for sucking, hard, soft or jellified sweets, or sugar-coated sweets; chewing gums; drinks; solutions intended to be incorporated into pastries (macaroons) , confectionery, flavoured sugars; powders to be diluted in water at the time of use; products that may be applied sublingually .

6. Process according to any one of Claims 1 to 5, in which the fragrancing composition (B) applied orally is an oral fragrancing agent containing at least two components, characterized in that it comprises:

b) at least one composition (B₂) comprising, in a support suitable for oral application, at least one edible fragrancing substance (2) that can, after ingestion or placing in the mouth, produce from within the body out to the human keratin materials, a fragrance whose diffusion reaches its maximum at a time of greater than or equal to 4 hours 30 minutes; the order of ingestion of compositions (Bi) and (B₂) being irrelevant; compositions (Bi) and (B₂) possibly being conditioned separately or together in the same galenical form; the said edible fragrancing substances (1) and (2) being chosen from those that produce perfumes with notes (head, heart and base) in the following olfactory families:

- citrine,

- ambery,

- floral,

- spicy,

- woody,

- oriental,

- gourmand,

- chypre,

- fougere,

- leathery.

7. Process according to Claim 6, in which the edible fragrancing substances (1) that can produce a perfume whose diffusion reaches its maximum at a time of less than 4 hours 30 minutes are chosen from essence of rose, citronellol, ethylvanillin, linalool, menthol and essence of pepper, or mixtures thereof.

8. Process according to Claim 6 or 7, in which the edible fragrancing substances (2) that can produce a perfume whose diffusion reaches its maximum at a time of greater than or equal to 4 hours 30 minutes are chosen from linalyl acetate, citral, essence of coriander, ethylmaltol, γ-undecalactone, terpineol and heliotropin, or mixtures thereof.

9. Process according to any one of Claims 1 to 8, in which the daily dose of the edible fragrancing molecule (s) ranges from 10^~5 to 200 mg and preferably from 1 to 50 mg.

10. Fragrancing kit or device containing at least two conditionings, characterized in that it comprises at least:

- a first conditioning comprising composition (A) as defined in any one of Claims 1 to 9, and

- a second conditioning comprising composition (B) as defined in any one of Claims 1 to 9.

11. Fragrancing kit or device according to Claim 10, characterized in that it comprises at least:

- a second conditioning comprising composition (Bi) as defined in any one of Claims 6 to 9, and

- a third conditioning comprising composition (B₂) as defined in any one of Claims 6 to 9.

12. Process for fragrancing human keratin materials, which consists in simultaneously or separately ingesting:

a) at least one composition (Bi) comprising, in a support suitable for oral application, at least one edible fragrancing substance (1) chosen from essence of rose, citronellol, menthol and essence of pepper, and b) at least one composition (B₂) comprising, in a support suitable for oral application, at least one edible fragrancing substance (2) chosen from geraniol, linalyl acetate, citral, essence of coriander, ethylmaltol, γ-undecalactone, terpineol and heliotropin;

the order of ingestion of compositions (Bi) and (B₂) being irrelevant; compositions (Bi) and (B₂) possibly being conditioned separately or together in the same galenical form.

13. Fragrancing kit or device for human keratin materials containing at least two conditionings, characterized in that it comprises at least:

- a first conditioning comprising composition (Bi) as defined in Claim 12; - a second conditioning comprising composition (B₂)fined in Claim 12.