WO2010096564A4 - Dietary supplements containing polyunsaturated omega-3 fatty acids and probiotic bacteria with potential gastrointestinal and dermatological benefits - Google Patents
Dietary supplements containing polyunsaturated omega-3 fatty acids and probiotic bacteria with potential gastrointestinal and dermatological benefits Download PDFInfo
- Publication number
- WO2010096564A4 WO2010096564A4 PCT/US2010/024594 US2010024594W WO2010096564A4 WO 2010096564 A4 WO2010096564 A4 WO 2010096564A4 US 2010024594 W US2010024594 W US 2010024594W WO 2010096564 A4 WO2010096564 A4 WO 2010096564A4
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- supplement
- fatty acids
- per gram
- polyunsaturated fatty
- probiotic bacteria
- Prior art date
Links
- 239000006041 probiotic Substances 0.000 title claims abstract 20
- 230000000529 probiotic effect Effects 0.000 title claims abstract 20
- 235000018291 probiotics Nutrition 0.000 title claims abstract 20
- 235000015872 dietary supplement Nutrition 0.000 title claims abstract 18
- 235000020660 omega-3 fatty acid Nutrition 0.000 title claims abstract 3
- 229940012843 omega-3 fatty acid Drugs 0.000 title claims abstract 3
- 241000894006 Bacteria Species 0.000 title claims 17
- 239000006014 omega-3 oil Substances 0.000 title claims 2
- 230000002496 gastric effect Effects 0.000 title 1
- 239000013589 supplement Substances 0.000 claims abstract 35
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims abstract 19
- 102000008186 Collagen Human genes 0.000 claims abstract 12
- 108010035532 Collagen Proteins 0.000 claims abstract 12
- 229920001436 collagen Polymers 0.000 claims abstract 12
- 244000199866 Lactobacillus casei Species 0.000 claims abstract 6
- 241000251468 Actinopterygii Species 0.000 claims abstract 5
- 235000013958 Lactobacillus casei Nutrition 0.000 claims abstract 5
- 235000019219 chocolate Nutrition 0.000 claims abstract 5
- 239000010638 cranberry seed oil Substances 0.000 claims abstract 5
- 229940017800 lactobacillus casei Drugs 0.000 claims abstract 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract 4
- 230000001815 facial effect Effects 0.000 claims abstract 4
- 210000001035 gastrointestinal tract Anatomy 0.000 claims abstract 4
- 239000002775 capsule Substances 0.000 claims abstract 3
- 239000000047 product Substances 0.000 claims abstract 3
- 229930003427 Vitamin E Natural products 0.000 claims abstract 2
- 230000000694 effects Effects 0.000 claims abstract 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract 2
- 235000020665 omega-6 fatty acid Nutrition 0.000 claims abstract 2
- 229940033080 omega-6 fatty acid Drugs 0.000 claims abstract 2
- 235000019165 vitamin E Nutrition 0.000 claims abstract 2
- 229940046009 vitamin E Drugs 0.000 claims abstract 2
- 239000011709 vitamin E Substances 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims 22
- 150000001413 amino acids Chemical class 0.000 claims 9
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 230000036559 skin health Effects 0.000 claims 3
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- 206010000059 abdominal discomfort Diseases 0.000 claims 1
- 239000013065 commercial product Substances 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 230000037406 food intake Effects 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 244000005706 microflora Species 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000037075 skin appearance Effects 0.000 claims 1
- 230000001502 supplementing effect Effects 0.000 claims 1
- 239000004615 ingredient Substances 0.000 abstract 2
- 235000013305 food Nutrition 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
This invention provides a new family of dietary supplements containing polyunsaturated fatty acids, a probiotic culture, and optionally hydrolyzed collagen. The prototype supplement contains cranberry seed oil as a source of omega-3 and omega-6 fatty acids, along with Vitamin E. The prototype supplement also contains a special strain of Lactobacillus casei as well as fish collagen. Nutritional supplements of this invention can be provided in capsule or tablet form, or as a food item such as a chocolate confectionary. Each of the three ingredients confers benefits on their own, allowing the consumer to get three nutritional supplements in the convenience of a single product. The ingredients are also believed to work synergistically to achieve a wider and more durable overall effect. In human clinical trials, consumption of the dietary supplement was associated subjective observations of improvement in softness and moisture of facial skin, reduction in wrinkles, and improvement in function of the gastrointestinal tract.
Claims
1. A dietary supplement formulated for oral consumption by human subjects, comprising at least 200 mg polyunsaturated fatty acids and at least 5 x 108 CFU's of probiotic bacteria per gram.
2. A dietary supplement formulated for oral consumption by human subjects, made by a process that includes:
a) obtaining or providing a source of lipids containing at least 400 mg per gram of polyunsaturated fatty acids per gram; and
b) adding at least 1 x 109 CFU's of probiotic bacteria per gram of lipids,
wherein the supplement produced according to the process comprises a least 200 mg polyunsaturated fatty acids per gram.
3. The supplement of either preceding clam, wherein the polyunsaturated fatty acids include at least 200 mg omega-3 fatty acids and at least 200 mg omega-6 fatty acids per gram.
4. The supplement of any preceding claim, wherein the polyunsaturated fatty acids are contained in a mixture of fatty acids extracted from one or more botanical sources.
5. The supplement of any preceding claim, wherein a source of the polyunsaturated fatty acids is cranberry seed oil.
6. The supplement of any preceding claim, which contains between about 400 and 800 mg of polyunsaturated fatty acids per gram.
7. The supplement of any preceding claim, wherein the probiotic bacteria are Lactobacillus casei.
8. The supplement of any preceding claim, wherein the probiotic bacteria are L. casei strain KE-99 (ATCC accession no. PTA-3945).
9. The supplement of any preceding claim, which contains between about 2 and 20 billion CFU's of the probiotic bacteria per gram.
10. The supplement of any preceding claim, also comprising a separate source of amino acids.
1 1. The supplement of claim 10, wherein the amino acid source is hydrolyzed collagen from fish.
12. The supplement of any preceding claim, which contains between 50 and 500 mg of protein or free amino acids per gram.
13. The supplement of any preceding claim, further comprising a substantial amount of vitamin E per gram.
14. A nutritional supplement for administration to human subjects, comprising at least 200 mg of polyunsaturated fatty acids from a botanical source, 1 x 109 CFU's of probiotic bacteria, and 100 mg of hydrolyzed collagen per gram.
15. The nutritional supplement of claim 14, comprising at least 200 mg of cranberry seed oil.
16. The nutritional supplement of claim 14, wherein the probiotic bacteria are Lactobacillus casei.
17. The nutritional supplement of claim 14, wherein the collagen has been obtained from fish.
18. A pharmaceutical capsule or tablet for oral ingestion containing at least 500 mg of the nutritional supplement of any preceding claim.
19. A chocolate confectionary containing at least 500 mg of the nutritional supplement of any of claims 1-17.
20. A method for preparing the supplement of any of claims 1 to 19, comprising combining a probiotic culture, a polyunsaturated oil, and optionally hydrolyzed collagen in a capsule.
21. A method for preparing the supplement of any of claims 1 to 19, comprising formulating a probiotic culture, a polyunsaturated oil, and optionally hydrolyzed collagen in a chocolate confectionary.
22. A method for increasing bioavailability of polyunsaturated fatty acids in a subject, comprising providing to the subject for the purpose of oral consumption a supplement according to any of claims 1 to 19.
23. A method for supplementing microflora in the gastrointestinal tract in a subject, comprising providing to the subject for the purpose of oral consumption a supplement according to any of claims 1 to 19.
24. A method for improving health of the intestine or reducing gas the gastrointestinal tract of a subject, comprising providing to the subject for the purpose of oral consumption a supplement according to any of claims 1 to 19.
25. A commercial product, comprising a plurality of daily doses of a supplement according to any of claims 1 to 19, packaged in a container with written information on consumption of the product or possible use of the product to improve function of the gastrointestinal tract or affect skin health or appearance.
26. Use of a combination of at least 100 mg polyunsaturated fatty acids, at least 5 x 108 CFU's of probiotic bacteria, and optionally between 50 and 500 mg of collagen per gram, in the treatment of gastrointestinal upset.
26
27. A method for increasing bioavailability of amino acids in a subject, comprising providing to the subject for the purpose of oral consumption a supplement comprising:
• at least 100 mg polyunsaturated fatty acids,
• at least 5 x 108 CFU's of probiotic bacteria, and
• between 50 and 500 mg of protein or free amino acids
per gram of supplement.
28. Use of a dietary supplement comprising::
• at least 100 mg polyunsaturated fatty acids,
• at least 5 x 108 CFU's of probiotic bacteria, and
• between 50 and 500 mg of protein or free amino acids
per gram of supplement, for increasing bioavailability of amino acids in a subject.
29. The method or use of claim 27 or 28, wherein the supplement comprises at least 100 mg of hydrolyzed collagen per gram.
30. The method or use of claim 29, wherein the collagen has been obtained from fish.
31. The method or use of any of claims 27 to 30, wherein said polyunsaturated fatty acids are from cranberry seed oil.
32. The method or use of any of claims 27 to 31 , wherein the probiotic bacteria are Lactobacillus casei.
33. The method or use of any of claims 27 to 32, wherein the supplement is formulated as a chocolate confectionary.
34. A method for improving skin health in a subject, comprising providing to the subject for the purpose of oral consumption a supplement comprising:
• at least 100 mg polyunsaturated fatty acids, and
• at least 5 x 108 CFU's of probiotic bacteria,
per gram of supplement.
35. A method for improving facial appearance of a subject, comprising providing to the subject for the purpose of oral consumption a supplement comprising:
• at least 100 mg polyunsaturated fatty acids, and
• at least 5 x 108 CFU's of probiotic bacteria,
per gram of supplement.
27
36. Use of a dietary supplement comprising:
• at least 100 mg polyunsaturated fatty acids, and
• at least 5 x 108 CFU's of probiotic bacteria,
per gram of supplement, for improving skin health in a subject.
37. Use of a dietary supplement comprising:
• at least 100 mg polyunsaturated fatty acids, and
• at least 5 x 108 CFU's of probiotic bacteria,
per gram of supplement, for improving facial appearance of a subject.
38. The method or use of any of claims 34 to 37, wherein the supplement further comprises a source of amino acids.
39. The method or use of claim 38, wherein the supplement comprises between 50 and 500 mg of protein or free amino acids per gram.
40. The method or use of claim 38, wherein the supplement comprises at least 100 mg of hydrolyzed collagen per gram.
41. The method or use of claim 40, wherein the collagen has been obtained from fish.
42. The method or use of any of claims 34 to 41 , wherein said polyunsaturated fatty acids are from cranberry seed oil.
43. The method or use of any of claims 33 to 41 , wherein the probiotic bacteria are Lactobacillus casei.
44. The method or use of any of claims 34 to 43, wherein the supplement is formulated as a chocolate confectionary.
45. Use of a dietary supplement as hereintofore described with reference to Example 1.
28
STATEMENT UNDER ARTICLE 19(1)
The replacement claims are related to the claims in the application as originally filed as follows:
• Claims 1 to 23 are unaltered.
• Claims 24 to 26 are renumbered from previous claim 26, 27, and 30 as originally presented.
• Claims 27 to 44 are new. They are based on claims 14-17 and 24-25 as originally presented (indicated in the International Search Report as being novel and inventive), in combination with features from claims 10, 12, and 19.
• Omnibus claim 45 refers to effect of the dietary supplements of the invention on skin and facial appearance, as documented in the clinical study presented as Example 1.
The amendments do not go beyond the disclosure in the international application as filed.
29
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20815009P | 2009-02-19 | 2009-02-19 | |
| US61/208,150 | 2009-02-19 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2010096564A2 WO2010096564A2 (en) | 2010-08-26 |
| WO2010096564A3 WO2010096564A3 (en) | 2011-04-07 |
| WO2010096564A4 true WO2010096564A4 (en) | 2011-07-14 |
Family
ID=42634439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2010/024594 WO2010096564A2 (en) | 2009-02-19 | 2010-02-18 | Dietary supplements containing polyunsaturated omega-3 fatty acids and probiotic bacteria with potential gastrointestinal and dermatological benefits |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2010096564A2 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2603208T3 (en) | 2010-08-10 | 2014-09-15 | Rp Scherer Technologies Llc | Process for preparing a stable soft gel capsule containing microencapsulated probiotic bacteria |
| FR2973650A1 (en) * | 2011-04-08 | 2012-10-12 | Frederic Pottecher | MEANS FOR HUNTING THE TASTE AND ODOR OF PEPTIDE HYDROLYSATES |
| EP2710901A1 (en) * | 2012-09-20 | 2014-03-26 | Symrise AG | Dietary supplement compositions |
| FI20126389L (en) * | 2012-12-28 | 2014-06-29 | Aromtech Ltd | Composition including capsule and seed oil |
| US9211277B2 (en) | 2013-02-07 | 2015-12-15 | Young Living Essential Oils, Lc | Dietary supplement composition |
| EP3595695A1 (en) * | 2017-03-15 | 2020-01-22 | Rousselot B.V. | Compositions of hydrolyzed collagen peptides and commensal microorganisms and methods thereof |
| US11896720B2 (en) * | 2017-09-26 | 2024-02-13 | Captek Softgel International | Orally available articles containing at least one stabilized supplement therein |
| WO2020018504A1 (en) * | 2018-07-16 | 2020-01-23 | Lonza Inc. | Collagen and cell matter supplement and method for administering same |
| IT201900008394A1 (en) * | 2019-06-07 | 2020-12-07 | Sofar Spa | Composition for use in the treatment of chronic inflammatory bowel diseases |
| WO2024144735A1 (en) * | 2022-12-28 | 2024-07-04 | Chivalric Regulus Biyoteknoloji Anonim Sirketi | A microencapsulated food supplement with probiotic microorganisms |
| WO2024167478A1 (en) * | 2023-02-06 | 2024-08-15 | Toplu Celal | Chocolate, wafer, tahini wafer, cream biscuit and tahini cream biscuit enriched with essential omega-3 alpha linolenic acid |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040009160A1 (en) * | 2001-06-22 | 2004-01-15 | Villamar Daniel F | Bioactive food complex, method for making bioactive food complex product and method for controlling disease |
| DK1992351T3 (en) * | 2007-05-18 | 2016-06-06 | Nestec Sa | Lactobacillus johnsonii for the prevention of post-surgical infection |
| EP2173856A1 (en) * | 2007-06-28 | 2010-04-14 | Chr. Hansen A/S | Treatment of cell suspension |
| MX2010001260A (en) * | 2007-08-03 | 2010-04-07 | Shaklee Corp | Nutritional supplement system. |
-
2010
- 2010-02-18 WO PCT/US2010/024594 patent/WO2010096564A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010096564A3 (en) | 2011-04-07 |
| WO2010096564A2 (en) | 2010-08-26 |
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