+

WO2010088667A1 - Crèmes topiques améliorées - Google Patents

Crèmes topiques améliorées Download PDF

Info

Publication number
WO2010088667A1
WO2010088667A1 PCT/US2010/022884 US2010022884W WO2010088667A1 WO 2010088667 A1 WO2010088667 A1 WO 2010088667A1 US 2010022884 W US2010022884 W US 2010022884W WO 2010088667 A1 WO2010088667 A1 WO 2010088667A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
camphor
phenol
menthol
acne
Prior art date
Application number
PCT/US2010/022884
Other languages
English (en)
Inventor
Niella Naidu
Original Assignee
Niella Naidu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Niella Naidu filed Critical Niella Naidu
Publication of WO2010088667A1 publication Critical patent/WO2010088667A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions

Definitions

  • the present invention relates to improved topical creams, Preferably, these creams are anti-acne creams * face creams and body skin creams.
  • these creams are anti-acne creams * face creams and body skin creams.
  • acne is a dermatologicat disorder that affects 20 to 25 million
  • acne produces a hypersecretion of the sebaceous glands
  • substances having a seboreguialing. or seboinhibiting activity fOOO ⁇
  • a ⁇ ti-microbial agents are often used. These compounds have been useful since all are active against the principle germs associated with acne, such as staphylococcus aureas, staphylococcus albus and especially eorynebaeterium acnes and Propionbacterium granules um.
  • the lesions associated with acne are the result of the rupture of a sebaceous follicle.
  • the lesions When the rapture is followed by inflammation and pus, the lesions is known as a whitehead.
  • the rupture is followed by the accumulation of clogged material in the sebaceous follicle and the lesion is then known as a blackhead.
  • This is caused by (he plugging of the upper portion of tire follicle, i.e., the pore, into which ⁇ sebum is secreted.
  • the pore is in direct communication with the skin surface and may be clogged by cells, sebum, bacteria and other debris.
  • the plugged sebaceous gland continues to produce sebum, stretching the mfundibulurn until the pore or a lower portion of the follicle ruptures.
  • the present invention provides other benefits for the skin, such as improving texture and feei.
  • the present invention relates to cosmetic and/or derraatologieal medicated compositions and methods for treatment of acne and its improvement and maintenance, together with conditioning of human skin, by improving texture and feel, which include those for regulating sebum on facial and the body skin of a human subject prowling cosmetic and or therapeutic benefits.
  • the topical agents work by normalizing the skin's production of keratin and the sebaceous gland's production of sebum, thereby preventing obstruction of the follicle while at the .same time attacking the mature pimples, blackheads- whiteheads, redness and dead skin cells to be exfoliated, and cleansing while nourishing and moisturizing the skin.
  • the skin becomes supple, soft, smooth and fcels good.
  • the present, invention through a blend of oils and compounds and extracts advantageously treats acne without any adverse effect, and conditions skin cells io reduce the likelihood of further acne.
  • Hie present invention provides such a topical treatment and in addition contains a skin cell conditioning and repairing component in an amount sufficient to properly regulate the sebum in the sebaceous glands and keratin production of the skm ceils as long as this topical invention is massaged well onto the skin and is consistently applied as directed,
  • lite present invention envisions three products:
  • Product I anti-acne cream composition for the healing, reduction and prevention of acne and for conditioning the skin cells that are inflicted with disorders, for men, women and teenagers;
  • Product II - lace cream for the purpose of conditioning skin, and preventing acne and other disorders while toning, moisturizing and softening skin, for men, women and teenagers;
  • Product 111 body skin cream, for prevention, maintenance, conditioning and moisturizing of chapped, dry skin, for men. women and teenagers.
  • Products comprise a base of an oleaginous base and emollient.
  • the concentration of camphor is greater than the concentration of phenol by weight, with the concentration of menthol by weight being about not less than the concentration of phenol and about no greater than die concentration of camphor. More preferably, the concentration of camphor is about twice the concentration of phenol by weight, and the concentration of menthol is about 60% the concentration of camphor by weight.
  • the above Products are topical cosmetic and/or dermatologies! medicated skin treatments. They include an acne healing and reducing component in an amount sufficient to reduce the swelling, redness and blemishes associated with acne as well as unplugging whiteheads and blackheads on the skin. They also control, exfoliate, clean, moisturize, tone and improve the condition and appearance of human skin, In addition to the acne healing and reducing component, the above products or formulations also include oleaginous base. They can be used to treat, heal and reduce acne as well as improve she condition and appearance of skin.
  • a 4 gram preparation contains about 1 % camphor by weight ⁇ eg., about ,04g) about i),6% menthol by weight (e.g., about .024g) and about 0.5% phenol by weight (e.g., aboui .02g).
  • the remainder comprises an oleaginous base such as petrolatum and emollients.
  • the emollients can be selected from the group consisting of cocoa butter, lanolin, light mineral oil, white wax, carnauba wax. araehidyl propionate, atyl alcohol, tsopt'ophyl myristate.
  • isopropyl ianolate methylparaben, oetyiadodeeanol, oleyl alcohol, paraffin, phenyl trimethicone or propyl paraben, or mixtures thereof. Fragrance can also be added.
  • the concentration of emollient is preferably greater than the concentration of oleaginous base. More preferably, the base of Product I contains about 40% by weight of oleaginous base and about 60% by weight emollient, More preferably, Product I contains about 45% oleaginous base with the remainder comprising emollient, camphor, menthol, phenol and other optional ingredients.
  • Product 1 can be massaged onto the skin, optionally with additional amounts added to acne infection, like cysts and mature pimples, 3 to 5 times a day until the face is cleared.
  • Product t can also be used to heal cuts, soothe rwuor bunts and stop minor burns from graduating into blisters when applied soon after the bum.
  • Product II discussed more MIy below, can be used as a preventative.
  • Product U of the instant invention is a face cream.
  • ft contains the .same active ingredients (about Mg camphor, about ,024g menthol and about ,02g phenol) as Product I, except they are in a total weight of 28 grams of Product and thus are more diluted.
  • Ilie remaining weight is oleaginous base such as petrolatum and emollients, with fragrance optional.
  • Product 31 will contain about .(M)14% by weight camphor, about .0009% by weight menthol and about .0007% by weight phenol.
  • Product Il preferably contains more oleaginous base than Product I. More preferably.
  • Product H contains about 55% by weight oleaginous base, with the remainder comprising the rest of the ingredients.
  • Product J Us a normal face cream and is used for normal or troubled skin to exfoliate, cleanse, moisturize, (one, maintain, condition, prevent and reduce acne, dry skin, wrinkles and other skin disorders. It can also be used to prevent water loss, heal cuts and keep dry shaved skin supple, moisturized and toned. It can be applied when needed, typically 1-2 times a day.
  • Product III also contains about .04g camphor, about ,024g menthol and about ,02g phenol, these ingredients would be contained in about 36 grams of product. Again, as was the ease with Product U, the remaining weight comprises oleaginous base such as petrolatum, emollients and optionally fragrance. Thus, Product HI will contain about ,0013% by weight camphor, about .00007% by weight menthol and about .00006% by weight phenol.
  • Product Ul preferably contains more oleaginous base than Product I or Product IL
  • Product 111 contains about 65-70% by weight oleaginous base, with the remainder comprising the rest of the ingredients.
  • Product IH is used for the maintenance of body skin, leaving a moist and healthy feei. It also helps prevent chapped skin. Product IH can also be used as a make-up remover. Product JII can be applied when needed, for example multiple times a day, daily or weekly, [00023]
  • the above Products can be compounded via any traditional technique.
  • the camphor, menthol and phenol are mixed together first, '(-hey can then be added to the oleaginous base with emollients and other ingredients (e.g., fragrance) added later or the oleaginous base and emollients can be mixed together first and men camphor-menthol-phenol mixture added to that.
  • the other ingredient can be added at any time.
  • the other ingredient can be added at any time.
  • some lightening of the skin might occur, although this is not a frequent or severe event.
  • the above topical preparations can contain other ingredients.
  • the preparation also contaias sun screen.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne des crèmes topiques améliorées. Ces crèmes comprennent une base oléagineuse et un émollient et contiennent également du camphre, du menthol et du phénol. Ces préparations sont utiles par exemple pour traiter l'acné.
PCT/US2010/022884 2009-02-02 2010-02-02 Crèmes topiques améliorées WO2010088667A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14903609P 2009-02-02 2009-02-02
US61/149,036 2009-02-02

Publications (1)

Publication Number Publication Date
WO2010088667A1 true WO2010088667A1 (fr) 2010-08-05

Family

ID=42396081

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/022884 WO2010088667A1 (fr) 2009-02-02 2010-02-02 Crèmes topiques améliorées

Country Status (1)

Country Link
WO (1) WO2010088667A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9623062B2 (en) * 2014-06-27 2017-04-18 Jeju National University Industryacademic Cooperation Foundation Anti-ageing activity of camphor in fibroblast cell line

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970216A (en) * 1986-03-17 1990-11-13 Richardson Vicks, Inc. Skin treatment composition and method
US5961997A (en) * 1997-03-25 1999-10-05 Swinehart; James M. Antipruritic composition
US20050042196A1 (en) * 2003-06-03 2005-02-24 Ian Askill Antimicrobial phenol containing cyanoacrylate compositions
US20070142317A1 (en) * 2003-12-29 2007-06-21 Qlt Usa, Inc. Topical composition for treatment of skin disorders

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970216A (en) * 1986-03-17 1990-11-13 Richardson Vicks, Inc. Skin treatment composition and method
US5961997A (en) * 1997-03-25 1999-10-05 Swinehart; James M. Antipruritic composition
US20050042196A1 (en) * 2003-06-03 2005-02-24 Ian Askill Antimicrobial phenol containing cyanoacrylate compositions
US20070142317A1 (en) * 2003-12-29 2007-06-21 Qlt Usa, Inc. Topical composition for treatment of skin disorders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9623062B2 (en) * 2014-06-27 2017-04-18 Jeju National University Industryacademic Cooperation Foundation Anti-ageing activity of camphor in fibroblast cell line

Similar Documents

Publication Publication Date Title
CN100496579C (zh) 止痒性组合物和促进创伤治愈的组合物
US11969405B2 (en) Method of treatment of topical dermatologic acne using a cream composition and method of manufacture
US20050244354A1 (en) Oxygenated personal care products
US6193987B1 (en) Lubricating composition for hands and skin
CN102342993B (zh) 一种皮肤抗敏修复外用制剂
US8394395B2 (en) Use of a cosmetic composition for the care of fatty skin
CN111920764A (zh) 用于表皮剥脱的组合物及其用途
KR20110036683A (ko) 피부 치료용 벤조일 퍼옥사이드 조성물
US20070172431A1 (en) Methods, systems and compositions for skin care
US7655255B2 (en) Topical composition for transdermal administration
CN113171327A (zh) 控油祛痘组合物及其应用
US20060222689A1 (en) Skin care compositions and methods
US20220183951A1 (en) Skin treatment methods and compositions with retinoid and delivery systems thereof
WO2011119247A2 (fr) Composition topique de soin de la peau
JP3590369B2 (ja) クリプトタンシノンを含むニキビ予防及び治療用化粧料組成物
KR100879094B1 (ko) 천연 정유 성분 및 그의 하이드로졸 성분을 함유하는 여드름 개선용 화장료 조성물
CN108938514B (zh) 一种清肤祛痘液及其制备方法
EP2046273A2 (fr) Agents thérapeutiques rincables pour le traitement de la peau
US20060292108A1 (en) Topical skin mask for oily and acneic skin
US20100285110A1 (en) Composition comprising mucilaginous polysaccharides derived from aloe barbadensis combined with liposomes, method for obtaining same and use thereof as a sun protector, an anti-acne agent, an epidermal regenerator and a moisturiser
WO2010088667A1 (fr) Crèmes topiques améliorées
CN107260622B (zh) 一种生肌敛口滋润保湿防裂膏及其制备方法
JP2002179519A (ja) 清浄な皮膚の状態を向上するための方法および組成物
KR102701789B1 (ko) 헤어 케어 조성물
KR20220151931A (ko) 여드름 피부 개선용 화장료 조성물

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10736570

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10736570

Country of ref document: EP

Kind code of ref document: A1

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载