+

WO2010066628A1 - Dispositif pour modifier le pouvoir réfringent de l'œil humain - Google Patents

Dispositif pour modifier le pouvoir réfringent de l'œil humain Download PDF

Info

Publication number
WO2010066628A1
WO2010066628A1 PCT/EP2009/066308 EP2009066308W WO2010066628A1 WO 2010066628 A1 WO2010066628 A1 WO 2010066628A1 EP 2009066308 W EP2009066308 W EP 2009066308W WO 2010066628 A1 WO2010066628 A1 WO 2010066628A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant
eye
frame
implants
frame parts
Prior art date
Application number
PCT/EP2009/066308
Other languages
German (de)
English (en)
Inventor
Stefan Clemens
Original Assignee
Ernst-Moritz-Arndt-Universität
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ernst-Moritz-Arndt-Universität filed Critical Ernst-Moritz-Arndt-Universität
Priority to EP09764811A priority Critical patent/EP2370024A1/fr
Publication of WO2010066628A1 publication Critical patent/WO2010066628A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants

Definitions

  • the invention relates to a device for changing the refractive power of the human eye for the purpose of eliminating myopia and / or hyperopia, as well as the astigmatism.
  • hyperopia hypermetropia
  • the colloquial hyperopia called hyperopia or hypermetropia means that the eyeball is too short in relation to the refractive power of the optical device of the eye or the lens is not curved enough. This leads to the fact that the image position (focal point) for optically infinitely distant objects with relaxed (not accommodated) eye not in the
  • Retinal level is what is required for a sharp visual impression. Instead, the (virtual) focal point of the far-sighted eye lies behind the retinal plane and results in a fuzzy visual impression. The closer an object is brought to the eye, the more the focus shifts to the rear and moves away from the retinal plane.
  • Myopia is another form of misdirection or ametropia. This is an optical aberration (aberration) in which the image position is in front of the retina.
  • Myopia is the geometric-optical opposite of hyperopia.
  • Short-sightedness and hyperopia (myopia and hyperopia) are also referred to as axial patches and are a low-order aberration.
  • Astigmatism, ie astigmatism referred called in optic ophthalmological optics, a special refractive property of the eyeball, in which the outgoing of object points, ie from the smallest details considered light rays do not reunite at a point on the retina, but there in an area, usually a stretch (hence: astigmatism).
  • the invention has for its object to provide a device for changing the refractive power of the human eye, which works without direct retinal surgery.
  • the invention provides at least one deformable from a compressed working position by means of an adjustment in an expanded end or initial position implant.
  • This makes it possible, by applying the implant to the dermis (sclera) of the human eye to shorten the axial length of the eye without retinal surgery, d. H. without having to intervene on the cornea, within the eye to anterior chamber, posterior chamber or additional so-called phakic lens implantation.
  • a therapeutic effect for the prevention of retinal detachment is also taken advantage of.
  • a frame-like implant and associated therewith, connected to two opposite parallel frame members adjusting means are provided to the two opposing frame parts of the implant in a compressed working position and the controlled re-deformation of the two frame parts to be deformed To deform implants in the expanded end or initial position.
  • the two frame parts to be deformed are formed in opposite directions trapezoidal.
  • the implant is formed from an elastically deformable material, in particular silicone.
  • a chain of several implants is provided, wherein the length of the chain corresponds to the circumference of the dermis (sclera) of the human eye.
  • the implant according to the invention is characterized in that the external shape and sheath of the dermis (sclera) of the eye for the purpose of achieving a reduced myopia or the establishment of legality is changed so that the refractive power by shortening the axial length of the eye in the legal range comes.
  • the axial length of the eye is shortened well-dosed. Without the opening of the inside of the eye and in contrast to retinal surgery, a gradual shortening of the axial length of the order of magnitude of between 1 and 4 mm is achieved for the purpose of refractive change. Should this happen within seconds, this axial contraction would create an immense pressure and seal the central artery. There would be a danger of blindness.
  • the drag mechanism formed by the chain of multiple implants allows a time-delayed shortening of the eye, without raising the pressure significantly. Over a period of two to four hours, with a pressure increase of, for example, normal 15 mm Hg to a maximum of 40 mm Hg, a gentle compression of the eye takes place.
  • the fixation of the necessary implants is done with a suture technique according to the principle limbusparalleler punctures and a suture channel with bridging character between peripherally and centrally.
  • the principle of a U- or tunnel or mattress suture is known from retinal surgery and advantageous with respect to the implants for a refractive change.
  • the individual implant is wrapped around the mattress seam according to the principle of a pulley arrangement.
  • the compressed shape of the implant is the working position during surgery.
  • the equatorial diameter of the eyeball is about 3 cm 2 on average.
  • a pressure increase of 15 to 40 mm Hg (mercury column, one millimeter of mercury corresponds to about 13 mm of water)
  • a circular force of about 70 pounds is required to achieve axis shortening via a gradual contraction of the prestressed seam.
  • ten implants are placed circularly in the chain, you should apply about 7 ponds per implant.
  • the seam tension and also the stress release of the implant itself are known.
  • the ten implants are connected by the chain of rigid individual elements, so that a contraction in the axial direction does not cause a circular secondary contraction.
  • the expanding implant takes from the prestressed state by gradual expansion and thus tightening the pulley seam and thus shortening the eye, the relaxed shape again.
  • a latching mechanism may be provided which stops the axis shortening step. Even if at some later time the pressure in the eye once over 40 mm Hg, which may be the case after a cataract operation or vitreous, but is retained by the latching mechanism the predetermined shape change.
  • an individual planning must be carried out as follows: measurement of the refractive power deviation of the eye, measurement of the axial length,
  • the device described is used to eliminate myopia together with the more or less pronounced astimatism of the cornea (astigmatism by different radii of curvature of the cornea).
  • the device can also be used in the case of farsightedness. In farsightedness, correction is not about shortening the eye to localize the internal focus on the retina, but on the contrary, prolonging the eye and also increasing the curvature of the cornea. Both effects have the goal to shift the focus in the eye from behind the retina to the retinal level.
  • the above-described device for changing the shape of the eye and thus the refractive power is just as well suited to convert the farsightedness into legality, to twist the individual compression elements or implants by 90 °, also put together in a chain.
  • the goal of these measures is the slow confinement of the eye in order to produce a slightly softened hourglass shape from a spherical shape.
  • This compression results in an extension of the optical axis of the eye.
  • Both mechanisms counteract the extension of the focus from behind the retina to the retinal level.
  • the drag mechanism described is crucial.
  • the compression must be very gentle and must not significantly affect intraocular pressure increase.
  • the pressure values must be kept to a maximum of 40 mmHg. Even better is a maximum pressure increase from normal 15 to 30 mmHg.
  • the strength of the compression effect of the individual implants with voltage generation of the sclera will still be the subject of experimental investigations in order to transmit them safely to humans.
  • Implant used, remotely controllable mechanical drive is formed.
  • the mechanical drive from a miniature drive with a worm and two driven by this worm wheels are formed, which are connected to the opposite frame parts, and introduced into a protective cover.
  • the basic principle of the first embodiment is maintained, however, proposed a supplement of the device by a remotely controllable mechanical drive to the individual elements of expandable implant, suture and connecting links, which includes the possibility of remote control bloodless from the outside, the refractive power at any time subsequently to zero again, or also any astigmatism (astigmatism or curvature of the entire eyeball) may be restored to the zero position.
  • the remote control takes place in such a way that transmission parts additionally within the expandable implant are set, which allow after the expansion, via an induction mechanism, a double worm gear, which transmits a fine tuning in the ratio of one revolution of the induction wheel to 1/40 turn in the expansion phase.
  • the connecting links between the individual expanding implants are changed by the remote control mechanism.
  • the drive technology runs through an axially circumferential mechanism, while in the actual implant, the axis of the induction wheel is radial. This can be used to make a subtle adjustment to the desired mechanism, either axial shortening or circumference change, from the outside.
  • the storage can be encapsulated within a protective envelope made of silicone rubber filled with silicone oil. This reduces the frictional resistance.
  • the frame of the implant may be made of silicone polymer or the above-mentioned materials, the gear parts such.
  • B. worm and worm wheels can be made of polyethylene or polyamide either in sintering or casting or in micro-punching technology.
  • the winding of the two induction wheels consists of a basket or cage anchor or a single non-magnetic ring z.
  • the drive from the outside is ensured by an alternating current device with 120 ° offset windings, which drive the cage anchor according to the principle of an asynchronous motor.
  • sensors in the drive can also be electronic feedback can be determined whether a rotation has occurred or not. If this does not work, the success can also be determined on the basis of the refraction change. On the part of the patient's cooperation, it must be expected that a glance is taken in the different directions in order to bring the remote control precisely to the surface of the eye in order to selectively address only one implant from a short distance.
  • the special feature of the combination of the expansion implant with the adjustment mechanism is that only after expansion of the implant, the mechanism engages and then can be effective. First, it is firstly not desirable and secondly, it can not accommodate meaningful space reasons synonymous useful.
  • the handset can be powered by a battery-operated device that can be held in the hand. Short circuits from a power line are thus excluded.
  • the handset must therefore contain a converter and a three-phase generator with a corresponding transformer and possibly thyristors. Such devices are already commercially in model making, z. As in helicopters, in the application.
  • the force that occurs with one revolution at the induction wheel must be around 50 micrograms and can serve as a target for the calculation of the dimensionality.
  • Fig.l is a plan view of the implant of
  • FIG. 3 shows the implant according to FIG. 2 in the compressed working position
  • FIG. 4 shows the side view of the human eye with circumferentially arranged tunnel seams for fastening the implants according to FIGS. 1 to 3, FIG.
  • FIG. 5 shows the principle of the tunnel seam on the dermis (sclera) of the eye according to FIG. 4, FIG.
  • FIG. 6 shows an applied to the dermis of the eye implant of FIG. 1 to 3 in the compressed working position of FIG. 3,
  • FIG. 7 shows the implant placed on the dermis according to FIG. 6 in the end position
  • Fig. 8 is a front view of the eye with ten am Equatorial circumference arranged, chain-like interconnected implants in the second embodiment
  • Fig. 9 is a plan view of the implanted implant in the second embodiment in expanded réellespp. end position
  • FIG. 10 shows the implant according to FIG. 9 in compressed working position
  • FIG. 11 is a view of the drive of FIG. 9,
  • FIG. 11 Drive according to FIG. 11 in the compressed working position of the implant in the case of non-latched bearing elements, FIG.
  • FIG. 13 shows the partial view according to FIG. 11 in the expanded end position of the implant with engaged bearing elements
  • the device for changing the refractive power of the human eye 9 comprises at least one, shown in Fig. 1, a frame-like implant 1, from an expanded starting or end position (Fig. 1 and 2) by means of a setting device 2 in a compressed Working position (Fig. 3) is deformable.
  • a frame-like implant 1 In the Nathans, End position (Fig. 1 and 2) are the maximum extension or width B of the implant 1 about 9.0 mm and the length L about 4.5 mm.
  • the width b is still 4.5 mm, so that the maximum working stroke is then still a maximum of 4.5 mm.
  • the thickness of the implant 1 is about 1.0 to 2.0 mm.
  • the adjustment device 2 comprises medical, thread-like suture material 3.
  • the frame-like implant 1 comprises two opposite, parallel frame parts 4, 5 extending in the longitudinal direction of the implant 1, with the adjusting device 2 for deforming the two other opposing frame parts 6, 7 of the implant 1, extending in the transverse direction of the implant 1
  • the compressed working position (Fig. 3) and the controlled remindver formation of the two frame parts to be deformed 6, 7 of the implant 1 in the expanded end or initial position (Fig. 2) are provided.
  • the two frame parts to be deformed 6, 7 of the implant 1 in the plan view of FIG. 1 and 2 are formed in opposite directions trapezoidal, the two frame parts 6, 7 due to their trapezoidal shape when compressed in the working position shown in Fig. 3, a resilient restoring force in build up the final or initial position.
  • the implant 1 is for this formed from an elastically deformable material.
  • plastics such as silicone, but also other date plastics in question, such.
  • acrylic, polyester, HEMA polyethylene, among others.
  • the adjusting device 2 further comprises in the outer sides of the two opposite, parallel frame parts 4, 5 each a pair of spaced notches 8 for a tunnel or Matatzennaht Adjust 27 (Fig. 5 to 7) from the medical, thread-like suture 3, so that a seam guide using the notches 8 is possible.
  • the frame-like implant 1 can be deformed from the expanded starting position shown in FIG. 2 into the compressed working position shown in FIG. 3 and back into the expanded end position according to FIGS. 1 and 2.
  • a chain 10 of several implants 1, in the exemplary embodiment ten implants 1, are sewn onto the equatorial circumference of the dermis (sclera) 26, the length of the chain 10 corresponding to the circumference of the dermis
  • Fig. 4 with pupil 11, eye muscles 12 and eye axis 25 is shown in principle.
  • the axial length Z of the eye 9 is about 24 mm.
  • the width A of the chain 10 from the implants 1 corresponds to the length L of the implants 1, ie about 4.5 mm.
  • the individual implants 1 of the chain 10 Before applying to the dermis (sclera) 26 have been spent by means of the adjustment device 2 in the form of the suture 3 and the formed from this U or tunnel seams 27 in the compressed working position shown in FIG.
  • Fig. 5 shows the principle of the dermis
  • FIG. 6 shows the arrangement of the implant 1 in the compressed working position shown in FIG. 3 on the dermis (sclera) 26 between the punctures 28 at a distance X of 10 mm, wherein the implant 1 has a width b of approximately 4.5 mm is compressed.
  • FIG. 7 shows the expanded end position of the implant 1 on the dermis 26, wherein the implant 1 expands to the width B of the end or initial position of about 9 mm and the distance y of the punctures 28 into the dermis 26 to about 8 mm is reduced.
  • FIG. 7 shows the slightly corrugated, contracted sclera 26 below the implant 1.
  • the circumference would not be changed, but only the axial length would be shortened.
  • each implant 1 is assigned a single adjustment device 2 in the form of the U or tunnel seam 27 from the suture 3, the U or tunnel seam 27 acting in the manner of a pulley or a pulley seam (pillar seam with a special thread guide).
  • the implant 1 is initially moved from the expanded starting position according to FIG. 2 into the compressed working position according to FIG. 3, in which each individual implant 1 of the chain 10 according to FIG. 6 is sewn onto the dermis of the eye 9. Due to the backward discharge of the pulley from the U or tunnel seam 27, each implant 1 is then guided back into the expanded end position according to FIG. 2 or FIG. 7 and thus acted on the eye 9 in the desired manner.
  • the implant 1 is characterized in that the outer shape and envelope of the eye 9, d. H. the dermis
  • Myopia and / or production of legality is changed so that the refractive power by shortening the
  • Axial length of the eye 9 comes in the legal area.
  • the peculiarity of the shortening of the eye 9 to cancel a stronger myopia of 8 to 18 diopters is that for this purpose the eye 9 in the axial direction, ie in the direction of the eye axis 25 by 3 to 6 mm must be shortened. Due to the toughness and rigidity of the dermis (Sclera) 26 would be at short-term contraction of the seams 27 an increase in pressure beyond the reasonable level must be done.
  • Towing mechanism for the gradual release of a tensile stress.
  • the drag mechanism of the chain 10 of implants 1 automatically remains in the grid position of the expanded end position of the implants 1 according to FIGS. 2 and 7, whereby the desired value of shortening the axial length of the eye 9 in the direction of the eye axis 25 is determined. Even with later taking place due to the disposition of the patient pressure increase thereby the eye 9 can not be longer again.
  • the drag mechanism of the chain 10 of implants 1 is ensured that equatorial circumferentially on the dermis (sclera) 26 of the eye 9 eight to twelve individual implants 1 are effective with the drag mechanism and thus a defined pressure increase of 40 mmHg is not exceeded.
  • the normal value is 15 mmHg with a tolerance of +/- 5 mmHg.
  • the implants 1 are used as shaped profiles made of silicone in the compressed working position according to FIG. 3 and FIG. 6 with the pulley seam or the U or tunnel seam 27 from the suture material 3. By gradual expansion of the implants 1 a kind of translation mechanism of relatively high expansion stress in distance to contraction on the eye 9 is implemented.
  • Contraction elements in the form of implants 1 absorb forces of the order of about 20 g. Circumferentially this gives a maximum contraction force of 200 g. Based on the cross-sectional area of the eye 9, this value then does not exceed the 40 mmHg and leads to a slow onset shortening of the eye 9. The eye 9 itself would with its gradual
  • Both the sutures and the expansion implants 1 have a non-resorbable character to hold the shape after the phase of change of the eye 9 and the reaching of the Einrastiss.
  • the described device from the implants 1 can be used reversibly, so that in an infection, incompatibility of the material, a tearing of the sutures 27, or a subsequent dilution of the dermis (sclera) 26 by rheumatoid changes the complete removal of the device is possible.
  • the conjunctiva of the eye 9 and the Tenon capsule have to be prepared in order to reach the implants 1.
  • the adjusting device 20 is formed from a remote-controlled mechanical drive 21 inserted into the frame-like implant 1.
  • This consists of FIG. 11 from a miniature drive with a worm 22 and two driven by this, gear-like worm wheels 23, which are in each case in operative connection with one of the opposite frame parts 4, 5 of the implant 1, so that the implant by means of the worm wheels 23 from the compressed work position in the expanded
  • FIGS. 11 to 13 show, threaded bushes 29 are inserted into the gearwheel-like worm wheels 23 in which threaded rods 30 can be moved, on the free ends of which bearing elements 31 can be screwed. These engage in stepped notches 32 on the
  • the implant 1 shown in Fig. 12 in compressed working position can be slowly deformed back into the end or initial position shown in Fig. 13 by the bearing elements 31 are moved on the ends of the threaded rods 31 to the outside and then into the notches 32 of the implant. 1 intervention. Since on both opposite frame parts 4, 5 of the implant 1 notches 32 and associated bearing elements 31 is disposed on the associated threaded rods 30, the thread formed on these must be formed in opposite directions to at the respective, generated by the worm 22 opposite rotational movement of the gearwheel-like worm wheels 23 all four bearing elements 31 simultaneously to be able to move outward into the respective notches 32.
  • the worm 22 and the worm wheels 23 cause a self-locking, so that the adjusted by the drive 21 end position of the implant 1 is maintained.
  • the mechanical drive 1 of the implant 1 is inserted into a protective cover, not shown, of silicone rubber.
  • the basic principle of the first embodiment is maintained, however, a supplement of the device by the remotely controllable mechanical drive 21 to the individual elements of expandable Implant 1, suture 3 and links 24 proposed, which includes the ability to remotely control the refractive power at any time subsequently to zero by remote control, or any astigmatism (corneal curvature or curvature of the entire eyeball) to put back to the zero position ,
  • the remote control takes place in such a way that within the expandable implant 1 the above-described
  • Transmission parts are additionally used, which allow after expansion, via an induction mechanism, the double worm gear 22, 23 in motion, which transmits a fine tuning in the ratio of one revolution at the induction wheel to 1/40 turn in the expansion phase.
  • the connecting links 24 between the individual expanding implants 1 are changed by the remote control mechanism, not shown.
  • the storage can be encapsulated within a protective envelope made of silicone rubber filled with silicone oil. This reduces the frictional resistance.
  • the frame formed from the frame parts 4 to 7 of the implant 1 can be made of silicone polymer or the above-mentioned materials, the gear parts such.
  • B. worm and worm wheels can be made of polyethylene or polyamide either in sintering or casting technique or in micro-punching technique.
  • the winding of the two induction wheels of the induction mechanism consists of a cage or cage anchor or a single non-magnetic ring, e.g. made of aluminum, platinum or titanium.
  • the drive from the outside is ensured by an alternating current device with 120 ° offset windings, which drive the cage anchor according to the principle of an asynchronous motor.
  • By appropriate sensor in the drive can also be detected electronically feedback, whether a rotation is done or not. If this does not work, the success can also be determined on the basis of the refraction change. On
  • the peculiarity of the combination of the expansion implant 1 with the adjustment mechanism is that only after the expansion of the implant 1, the mechanism shown in Fig. 12 and 13 engages and then can be effective. First, it is firstly not desirable and secondly, it can not accommodate meaningful space reasons synonymous useful.
  • the drive 21 can be done via a battery powered device that can be held in the hand. Short circuits from a power line are then eliminated. concluded.
  • the handset must include a converter and a three-phase alternator with appropriate transformer and possibly thyristors. Such devices are already commercially in model making, z. As in helicopters, in the application.
  • the force that occurs with one revolution at the induction wheel must be around 50 micrograms and can serve as a target for the calculation of the dimensionality.

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention porte sur un dispositif destiné à modifier le pouvoir réfringent de l'œil humain par une déformation de la sclérotique. Pour que ce dispositif fonctionne, il est prévu au moins un implant (1), en forme de cadre, déformable à partir d'une position de travail comprimée, au moyen d'un dispositif de réglage (2), pour prendre une position finale ou initiale expansée, l'implant (1) en forme de cadre, le dispositif de réglage (2), qui lui est affecté, et est relié à deux parties de cadre (4, 5) parallèles et opposées l'une à l'autre, servant à la déformation des deux autres parties de cadre (6, 7) opposées l'une à l'autre, de l'implant (1), jusqu'à la position de travail comprimée, et à la déformation pilotée en retour des deux parties de cadre (6, 7) à déformer de l'implant (1), pour les mettre dans la position finale ou initiale expansée.
PCT/EP2009/066308 2008-12-12 2009-12-03 Dispositif pour modifier le pouvoir réfringent de l'œil humain WO2010066628A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09764811A EP2370024A1 (fr) 2008-12-12 2009-12-03 Dispositif pour modifier le pouvoir réfringent de l' il humain

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008061647.8 2008-12-12
DE200810061647 DE102008061647B4 (de) 2008-12-12 2008-12-12 Vorrichtung zur Änderung der Brechkraft des menschlichen Auges

Publications (1)

Publication Number Publication Date
WO2010066628A1 true WO2010066628A1 (fr) 2010-06-17

Family

ID=41664592

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/066308 WO2010066628A1 (fr) 2008-12-12 2009-12-03 Dispositif pour modifier le pouvoir réfringent de l'œil humain

Country Status (3)

Country Link
EP (1) EP2370024A1 (fr)
DE (1) DE102008061647B4 (fr)
WO (1) WO2010066628A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824086A (en) * 1993-08-02 1998-10-20 Keravision, Inc. Segmented pre-formed intrastromal corneal insert
WO2002011648A1 (fr) * 2000-08-04 2002-02-14 Environmental Robots, Inc. Correction refractive par implants musculaires artificiels actifs
US20060116759A1 (en) * 2004-11-30 2006-06-01 Thornton Spencer P Method of treating presbyopia and other eye conditions
US20080097596A1 (en) * 2006-10-18 2008-04-24 Christ F Richard Injection of anti-presbyopia corrective element precursor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824086A (en) * 1993-08-02 1998-10-20 Keravision, Inc. Segmented pre-formed intrastromal corneal insert
WO2002011648A1 (fr) * 2000-08-04 2002-02-14 Environmental Robots, Inc. Correction refractive par implants musculaires artificiels actifs
US20060116759A1 (en) * 2004-11-30 2006-06-01 Thornton Spencer P Method of treating presbyopia and other eye conditions
US20080097596A1 (en) * 2006-10-18 2008-04-24 Christ F Richard Injection of anti-presbyopia corrective element precursor

Also Published As

Publication number Publication date
EP2370024A1 (fr) 2011-10-05
DE102008061647B4 (de) 2011-04-21
DE102008061647A1 (de) 2010-06-17

Similar Documents

Publication Publication Date Title
DE69917931T2 (de) Akkomodationsfähige intraocularlinse
DE4403326C1 (de) Intraokulare Linsenanordnung zur Astigmatismuskorrektur
DE69433855T3 (de) Intraokularlinse zur Akkommodation
DE69916097T2 (de) Multifokale akkomodationsfähige intraokularlinse
DE69333904T2 (de) Behandlung von Altersweitsichtigkeit und anderen Augenkrankheiten
DE69526962T2 (de) Akkomodierendes kuenstliches linsenimplantat
EP2887908B1 (fr) Lentille intraoculaire, notamment lentille intraoculaire à sac capsulaire
EP2887907B1 (fr) Lentille intraoculaire, notamment lentille intraoculaire ciliaire
DE60307521T2 (de) Akkommodative intraokularlinse
DE3348066C2 (fr)
DE60118522T2 (de) Intraokulare linse befestigt an der iris
DE69919893T2 (de) Vorrichtung zur behandlung der weitsichtigkeit oder anderer augenbeschwerden
EP1658021B1 (fr) Implant cristallinien actionne par le muscle ciliaire et apte a l'accommodation
DE3632835A1 (de) Verbesserte instrumente zur implantation deformierbarer intraokularer linsenstrukturen
DE60027290T2 (de) Skleraprothese zur behandlung der weitsichtigkeit und anderer augenkrankheiten
DE10346024A1 (de) Ciliarmuskel-betätigtes, akkommodationsfähiges Linsenimplantat
EP2907489A1 (fr) Dispositif de réticulation d'un tissu oculaire à l'aide d'un rayonnement électromagnétique
DE60029102T2 (de) Bewegbare intraokularlinse
DE60201010T2 (de) Element zur presbyopiekorrektur
DE3902560A1 (de) Verfahren zur erzeugung einer expansiblen intraokulaeren hydrogel-linse, material zur durchfuehrung desselben sowie daraus hergestellte linse
DE102008061647B4 (de) Vorrichtung zur Änderung der Brechkraft des menschlichen Auges
DE69428807T2 (de) Verfahren zur auswahl einer vorrichtung zum modifizieren der brechungseigenschaften der hornhaut
DE19538951C2 (de) Vorrichtung zum Spreizen einer Augeniris
WO2006117208A1 (fr) Implant oculaire
WO2013086644A1 (fr) Anneau de tension capsulaire chirurgical pour ophtalmologie

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09764811

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009764811

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载