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WO2010058393A3 - Compositions et procédés pour le pronostic du cancer du côlon - Google Patents

Compositions et procédés pour le pronostic du cancer du côlon Download PDF

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Publication number
WO2010058393A3
WO2010058393A3 PCT/IL2009/001075 IL2009001075W WO2010058393A3 WO 2010058393 A3 WO2010058393 A3 WO 2010058393A3 IL 2009001075 W IL2009001075 W IL 2009001075W WO 2010058393 A3 WO2010058393 A3 WO 2010058393A3
Authority
WO
WIPO (PCT)
Prior art keywords
prognosis
compositions
colon cancer
methods
derived
Prior art date
Application number
PCT/IL2009/001075
Other languages
English (en)
Other versions
WO2010058393A2 (fr
Inventor
Gila Lithwick Yanai
Baruch Brenner
Original Assignee
Rosetta Genomics Ltd.
Mor Research Applications
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rosetta Genomics Ltd., Mor Research Applications filed Critical Rosetta Genomics Ltd.
Publication of WO2010058393A2 publication Critical patent/WO2010058393A2/fr
Publication of WO2010058393A3 publication Critical patent/WO2010058393A3/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des compositions et des procédés pour le pronostic du cancer du côlon. Les compositions sont des molécules de microARN associées au pronostic du cancer du côlon, ainsi que différentes molécules d'acide nucléique apparentées à ou dérivées de celles-ci.
PCT/IL2009/001075 2008-11-20 2009-11-15 Compositions et procédés pour le pronostic du cancer du côlon WO2010058393A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11630108P 2008-11-20 2008-11-20
US61/116,301 2008-11-20

Publications (2)

Publication Number Publication Date
WO2010058393A2 WO2010058393A2 (fr) 2010-05-27
WO2010058393A3 true WO2010058393A3 (fr) 2010-08-12

Family

ID=42198596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/001075 WO2010058393A2 (fr) 2008-11-20 2009-11-15 Compositions et procédés pour le pronostic du cancer du côlon

Country Status (1)

Country Link
WO (1) WO2010058393A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3214185A1 (fr) * 2010-12-01 2017-09-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédé de prévision du résultat d'un cancer par l'analyse de l'expression miarn
US20120184453A1 (en) * 2011-01-13 2012-07-19 Industrial Technology Research Institute Biomarkers for recurrence prediction of colorectal cancer
BR112013029857A2 (pt) 2011-05-24 2017-11-28 Mor Research Applic Ltd métodos e composições para determinação de insuficiência cardíaca ou risco de insuficiência cardíaca
US20150292023A1 (en) * 2011-12-01 2015-10-15 Ohio State Innovation Foundation Materials and Methods Related to NSAID Chemoprevention in Colorectal Cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081740A2 (fr) * 2006-01-05 2007-07-19 The Ohio State University Research Foundation Méthodes et compositions basés sur des micro-arn et s'appliquant au diagnostic et au traitement de cancers solides
WO2008029295A2 (fr) * 2006-06-30 2008-03-13 Rosetta Genomics Ltd Procédé pour détecter des acides nucléiques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081740A2 (fr) * 2006-01-05 2007-07-19 The Ohio State University Research Foundation Méthodes et compositions basés sur des micro-arn et s'appliquant au diagnostic et au traitement de cancers solides
WO2008029295A2 (fr) * 2006-06-30 2008-03-13 Rosetta Genomics Ltd Procédé pour détecter des acides nucléiques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MYERS.: "Types of Colon Cancer.", ABOUT.COM, 17 October 2007 (2007-10-17), Retrieved from the Internet <URL:http://web.archive.org/web/20071017140923/http://coloncancer.about.com/od/typesofcancer/alTypeColonCancer.htm> [retrieved on 20100512] *
VOLINIA ET AL.: "A microRNA expression signature of human solid tumors defines cancer gene targets.", PROC NAT ACAD SCI, vol. 103, no. 7, 14 February 2006 (2006-02-14), pages 2257 - 2261 *

Also Published As

Publication number Publication date
WO2010058393A2 (fr) 2010-05-27

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