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WO2009146151A3 - Corneal onlay devices and methods - Google Patents

Corneal onlay devices and methods Download PDF

Info

Publication number
WO2009146151A3
WO2009146151A3 PCT/US2009/039675 US2009039675W WO2009146151A3 WO 2009146151 A3 WO2009146151 A3 WO 2009146151A3 US 2009039675 W US2009039675 W US 2009039675W WO 2009146151 A3 WO2009146151 A3 WO 2009146151A3
Authority
WO
WIPO (PCT)
Prior art keywords
onlay
cornea
adhere
layer
methods
Prior art date
Application number
PCT/US2009/039675
Other languages
French (fr)
Other versions
WO2009146151A2 (en
Inventor
Eugene De Juan
Cary J. Reich
Stephen Boyd
David Sierra
Jose D. Alejandro
Original Assignee
Forsight Labs, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forsight Labs, Llc filed Critical Forsight Labs, Llc
Priority to EP09755513A priority Critical patent/EP2296580A2/en
Publication of WO2009146151A2 publication Critical patent/WO2009146151A2/en
Publication of WO2009146151A3 publication Critical patent/WO2009146151A3/en
Priority to US12/897,131 priority patent/US9125735B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
    • A61F2/1451—Inlays or onlays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
    • A61F2/1453—Corneal lenses connected to distinct attachment means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0019—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A corneal (100) only is configured to adhere to the cornea so as to inhibit epithelial growth under the onlay. Structures can be provided on the onlay to adhere the onlay to the eye. At least one of an epithelial layer or the water inhibiting layer can be provided on or over the onlay, for example a natural epithelial layer or water inhibiting layer that inhibits, for example minimizes, water penetration into the onlay, so as to adhere the onlay to the eye with pumping of the endothelium. The water inhibiting layer may comprise a therapeutic covering positioned over the onlay to inhibit swelling of the cornea. The posterior surface of the onlay may be shaped so as to fit the anterior exposed surface of the cornea.
PCT/US2009/039675 2008-04-04 2009-04-06 Corneal onlay devices and methods WO2009146151A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09755513A EP2296580A2 (en) 2008-04-04 2009-04-06 Corneal onlay devices and methods
US12/897,131 US9125735B2 (en) 2008-04-04 2010-10-04 Method of correcting vision using corneal onlays

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US4259408P 2008-04-04 2008-04-04
US4258908P 2008-04-04 2008-04-04
US61/042,589 2008-04-04
US61/042,594 2008-04-04
US5010608P 2008-05-02 2008-05-02
US5014708P 2008-05-02 2008-05-02
US61/050,106 2008-05-02
US61/050,147 2008-05-02
US19191508P 2008-09-11 2008-09-11
US61/191,915 2008-09-11
US11971208P 2008-12-03 2008-12-03
US61/119,712 2008-12-03
US21181509P 2009-04-03 2009-04-03
US61/211,815 2009-04-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/897,131 Continuation US9125735B2 (en) 2008-04-04 2010-10-04 Method of correcting vision using corneal onlays

Publications (2)

Publication Number Publication Date
WO2009146151A2 WO2009146151A2 (en) 2009-12-03
WO2009146151A3 true WO2009146151A3 (en) 2010-01-14

Family

ID=41258210

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/039675 WO2009146151A2 (en) 2008-04-04 2009-04-06 Corneal onlay devices and methods

Country Status (2)

Country Link
EP (1) EP2296580A2 (en)
WO (1) WO2009146151A2 (en)

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US9020580B2 (en) 2011-06-02 2015-04-28 Avedro, Inc. Systems and methods for monitoring time based photo active agent delivery or photo active marker presence
US9498122B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498642B2 (en) 2009-10-21 2016-11-22 Avedro, Inc. Eye therapy system

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US7668325B2 (en) 2005-05-03 2010-02-23 Earlens Corporation Hearing system having an open chamber for housing components and reducing the occlusion effect
EP2208367B1 (en) 2007-10-12 2017-09-27 Earlens Corporation Multifunction system and method for integrated hearing and communiction with noise cancellation and feedback management
US8545487B2 (en) 2007-12-05 2013-10-01 Avedro Inc. Eye therapy system
CA2720250C (en) 2008-04-04 2018-01-23 Forsight Labs, Llc Therapeutic device for pain management and vision
US8715152B2 (en) 2008-06-17 2014-05-06 Earlens Corporation Optical electro-mechanical hearing devices with separate power and signal components
WO2010033932A1 (en) 2008-09-22 2010-03-25 Earlens Corporation Transducer devices and methods for hearing
US8506473B2 (en) 2008-12-16 2013-08-13 SoundBeam LLC Hearing-aid transducer having an engineered surface
US8109997B2 (en) * 2009-01-18 2012-02-07 Eyeon Medical Ltd. Hydrophobic pseudo-endothelial implants for treating corneal edema
WO2011050327A1 (en) 2009-10-23 2011-04-28 Forsight Labs Llc Corneal denervation for treatment of ocular pain
EP2490620A4 (en) 2009-10-23 2017-03-22 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
EP4480461A3 (en) 2010-03-19 2025-02-12 Avedro, Inc. Systems for applying and monitoring eye therapy
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
EP2656639B1 (en) 2010-12-20 2020-05-13 Earlens Corporation Anatomically customized ear canal hearing apparatus
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
WO2014210186A2 (en) 2013-06-26 2014-12-31 Nexisvision, Inc. Contact lenses for refractive correction
US9044308B2 (en) 2011-05-24 2015-06-02 Avedro, Inc. Systems and methods for reshaping an eye feature
ES2986057T3 (en) 2012-03-29 2024-11-08 Epion Therapeutics Inc Compositions and methods for treating or preventing diseases associated with oxidative stress
EP4420725A3 (en) 2012-03-29 2025-04-16 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
US9555111B2 (en) 2012-03-29 2017-01-31 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
EP4074294A1 (en) 2012-07-16 2022-10-19 Avedro, Inc. Systems and methods for corneal cross-linking with pulsed light
US10092393B2 (en) 2013-03-14 2018-10-09 Allotex, Inc. Corneal implant systems and methods
CN103272268B (en) * 2013-05-16 2015-04-22 华南理工大学 Antibacterial cornea repairing material and preparation method thereof
US10034103B2 (en) 2014-03-18 2018-07-24 Earlens Corporation High fidelity and reduced feedback contact hearing apparatus and methods
WO2016011044A1 (en) 2014-07-14 2016-01-21 Earlens Corporation Sliding bias and peak limiting for optical hearing devices
KR102416876B1 (en) 2014-10-27 2022-07-05 아베드로 인코퍼레이티드 Systems and methods for cross-linking treatments of an eye
WO2016077747A1 (en) 2014-11-13 2016-05-19 Avedro, Inc. Multipass virtually imaged phased array etalon
US9924276B2 (en) 2014-11-26 2018-03-20 Earlens Corporation Adjustable venting for hearing instruments
EP3827792A1 (en) 2015-04-24 2021-06-02 Avedro, Inc. Systems and methods for photoactivating a photosensitizer applied to an eye
EP4483884A3 (en) 2015-05-22 2025-03-05 Avedro Inc. Systems for monitoring cross-linking activity for corneal treatments
EP3324973B1 (en) 2015-07-21 2020-06-03 Avedro, Inc. Treament of an eye with a photosensitizer
US10449090B2 (en) 2015-07-31 2019-10-22 Allotex, Inc. Corneal implant systems and methods
EP3888564B1 (en) 2015-10-02 2025-04-09 Earlens Corporation Drug delivery customized ear canal apparatus
US10492010B2 (en) 2015-12-30 2019-11-26 Earlens Corporations Damping in contact hearing systems
US10178483B2 (en) 2015-12-30 2019-01-08 Earlens Corporation Light based hearing systems, apparatus, and methods
US11350226B2 (en) 2015-12-30 2022-05-31 Earlens Corporation Charging protocol for rechargeable hearing systems
EP3510796A4 (en) 2016-09-09 2020-04-29 Earlens Corporation Contact hearing systems, apparatus and methods
US20190201710A1 (en) * 2016-09-27 2019-07-04 KeraMed, Inc. System, device, and method for cross-linking corneal tissue
WO2018093733A1 (en) 2016-11-15 2018-05-24 Earlens Corporation Improved impression procedure
US10966863B2 (en) 2018-01-08 2021-04-06 EyeYon Medical Ltd. Treatment to improve adhesive properties of corneal implant
EP3761927B1 (en) 2018-03-05 2024-01-31 Avedro, Inc. System for eye tracking during eye treatment
WO2019173470A1 (en) 2018-03-07 2019-09-12 Earlens Corporation Contact hearing device and retention structure materials
EP3761928A1 (en) 2018-03-08 2021-01-13 Avedro, Inc. Micro-devices for treatment of an eye
WO2019199680A1 (en) 2018-04-09 2019-10-17 Earlens Corporation Dynamic filter
AU2019345058B2 (en) 2018-09-19 2024-12-05 Avedro, Inc. Systems and methods for eye tracking during eye treatment
EP3863576A4 (en) 2018-10-09 2022-07-06 Avedro, Inc. Photoactivation systems and methods for corneal cross-linking treatments
CN113286788A (en) * 2018-10-24 2021-08-20 加州理工学院 Treatment of myopia and other eye disorders using singlet oxygen
EP3930648A4 (en) 2019-02-26 2022-11-23 Avedro, Inc. SYSTEMS AND METHODS FOR CROSS-LINKING EYE TREATMENTS
CA3147045A1 (en) 2019-08-06 2021-02-11 Desmond C. Adler Photoactivation systems and methods for corneal cross-linking treatments
US11737919B2 (en) * 2021-06-17 2023-08-29 EyeYon Medical Ltd. Endothelial ocular implant
WO2022272082A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Corneal onlay medical device

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US4810082A (en) * 1987-07-01 1989-03-07 Abel Robert Jr Corneal onlay lens
EP0434205A2 (en) * 1989-11-22 1991-06-26 Allergan, Inc Corneal onlay lenses and methods for attaching same
WO1995013764A1 (en) * 1993-11-19 1995-05-26 Ciba-Geigy Ag Corneal onlays
WO2000009042A1 (en) * 1998-08-12 2000-02-24 Novartis Ag Corneal onlay
WO2002068008A1 (en) * 2001-02-28 2002-09-06 Novartis Pharma Gmbh Coated biomedical devices
WO2003097759A1 (en) * 2002-05-21 2003-11-27 Commonwealth Scientific And Industrial Research Organisation Biomedical adhesive
US20040184158A1 (en) * 2002-02-06 2004-09-23 Shadduck John H. Adaptive optic lens and method of making
US20050259221A1 (en) * 2004-05-20 2005-11-24 Coopervision, Inc Corneal onlays and wavefront aberration correction to enhance vision
CA2174967C (en) * 1993-11-19 2006-03-14 John Gerard Steele Corneal onlays
US20060083773A1 (en) * 2004-10-05 2006-04-20 David Myung Artificial corneal implant
US20060241751A1 (en) * 2002-09-13 2006-10-26 Marmo J C Corneal onlays and methods of producing same

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810082A (en) * 1987-07-01 1989-03-07 Abel Robert Jr Corneal onlay lens
EP0434205A2 (en) * 1989-11-22 1991-06-26 Allergan, Inc Corneal onlay lenses and methods for attaching same
WO1995013764A1 (en) * 1993-11-19 1995-05-26 Ciba-Geigy Ag Corneal onlays
CA2174967C (en) * 1993-11-19 2006-03-14 John Gerard Steele Corneal onlays
WO2000009042A1 (en) * 1998-08-12 2000-02-24 Novartis Ag Corneal onlay
WO2002068008A1 (en) * 2001-02-28 2002-09-06 Novartis Pharma Gmbh Coated biomedical devices
US20040184158A1 (en) * 2002-02-06 2004-09-23 Shadduck John H. Adaptive optic lens and method of making
WO2003097759A1 (en) * 2002-05-21 2003-11-27 Commonwealth Scientific And Industrial Research Organisation Biomedical adhesive
US20060241751A1 (en) * 2002-09-13 2006-10-26 Marmo J C Corneal onlays and methods of producing same
US20050259221A1 (en) * 2004-05-20 2005-11-24 Coopervision, Inc Corneal onlays and wavefront aberration correction to enhance vision
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US20060083773A1 (en) * 2004-10-05 2006-04-20 David Myung Artificial corneal implant

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9498642B2 (en) 2009-10-21 2016-11-22 Avedro, Inc. Eye therapy system
US9020580B2 (en) 2011-06-02 2015-04-28 Avedro, Inc. Systems and methods for monitoring time based photo active agent delivery or photo active marker presence
US9498122B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment

Also Published As

Publication number Publication date
EP2296580A2 (en) 2011-03-23
WO2009146151A2 (en) 2009-12-03

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