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WO2009037660A3 - Analysing the binding of cell membrane bound molecules - Google Patents

Analysing the binding of cell membrane bound molecules Download PDF

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Publication number
WO2009037660A3
WO2009037660A3 PCT/IB2008/053790 IB2008053790W WO2009037660A3 WO 2009037660 A3 WO2009037660 A3 WO 2009037660A3 IB 2008053790 W IB2008053790 W IB 2008053790W WO 2009037660 A3 WO2009037660 A3 WO 2009037660A3
Authority
WO
WIPO (PCT)
Prior art keywords
binding
cell membrane
membrane bound
analysing
bound molecules
Prior art date
Application number
PCT/IB2008/053790
Other languages
French (fr)
Other versions
WO2009037660A2 (en
Inventor
Electra Gizeli
Michail Saitakis
Original Assignee
Foundation For Res And Technol
Electra Gizeli
Michail Saitakis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foundation For Res And Technol, Electra Gizeli, Michail Saitakis filed Critical Foundation For Res And Technol
Publication of WO2009037660A2 publication Critical patent/WO2009037660A2/en
Publication of WO2009037660A3 publication Critical patent/WO2009037660A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/032—Analysing fluids by measuring attenuation of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/30—Arrangements for calibrating or comparing, e.g. with standard objects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02466—Biological material, e.g. blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02818—Density, viscosity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0422—Shear waves, transverse waves, horizontally polarised waves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Acoustics & Sound (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

A method of analysing the binding of cell membrane bound molecules to specific binding molecules by using a liquid-phase acoustic sensor device to monitor the change in a signal whilst cell membrane bound molecules form specific bonds with binding molecules immobilised on the sensing surface of the liquid-phase acoustic sensor device.
PCT/IB2008/053790 2007-09-17 2008-09-17 Analysing the binding of cell membrane bound molecules WO2009037660A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0718073.0 2007-09-17
GB0718073A GB0718073D0 (en) 2007-09-17 2007-09-17 Analysing the binding of cell membrane bound molecules

Publications (2)

Publication Number Publication Date
WO2009037660A2 WO2009037660A2 (en) 2009-03-26
WO2009037660A3 true WO2009037660A3 (en) 2009-07-30

Family

ID=38659065

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/053790 WO2009037660A2 (en) 2007-09-17 2008-09-17 Analysing the binding of cell membrane bound molecules

Country Status (2)

Country Link
GB (1) GB0718073D0 (en)
WO (1) WO2009037660A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2515111A1 (en) 2011-04-19 2012-10-24 SAW instruments GmbH Analytical method to investigate binding of analyte ligands to cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006068619A1 (en) * 2004-12-23 2006-06-29 Nanoxis Ab Device and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006068619A1 (en) * 2004-12-23 2006-06-29 Nanoxis Ab Device and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COOPER M A ET AL: "Direct and sensitive detection of a human virus by rupture event scanning.", NATURE BIOTECHNOLOGY SEP 2001, vol. 19, no. 9, September 2001 (2001-09-01), pages 833 - 837, XP002527915, ISSN: 1087-0156 *
WEGENER J ET AL: "Analysis of the composite response of shear wave resonators to the attachment of mammalian cells.", BIOPHYSICAL JOURNAL JUN 2000, vol. 78, no. 6, June 2000 (2000-06-01), pages 2821 - 2833, XP002527914, ISSN: 0006-3495 *

Also Published As

Publication number Publication date
GB0718073D0 (en) 2007-10-24
WO2009037660A2 (en) 2009-03-26

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