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WO2009007334A3 - Systèmes thérapeutiques transdermiques contenant le principe actif anastrozol - Google Patents

Systèmes thérapeutiques transdermiques contenant le principe actif anastrozol Download PDF

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Publication number
WO2009007334A3
WO2009007334A3 PCT/EP2008/058743 EP2008058743W WO2009007334A3 WO 2009007334 A3 WO2009007334 A3 WO 2009007334A3 EP 2008058743 W EP2008058743 W EP 2008058743W WO 2009007334 A3 WO2009007334 A3 WO 2009007334A3
Authority
WO
WIPO (PCT)
Prior art keywords
substance
anastrozole
transdermal therapeutic
contain
layer
Prior art date
Application number
PCT/EP2008/058743
Other languages
German (de)
English (en)
Other versions
WO2009007334A2 (fr
Inventor
Christian Braetter
Original Assignee
Christian Braetter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christian Braetter filed Critical Christian Braetter
Priority to EP08774817A priority Critical patent/EP2178523A2/fr
Publication of WO2009007334A2 publication Critical patent/WO2009007334A2/fr
Publication of WO2009007334A3 publication Critical patent/WO2009007334A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention se rapporte à un système thérapeutique transdermique (STT) comprenant une couche de support imperméable au principe actif, une couche adhésive (couche contenant le principe actif) contenant un composant adhésif et le principe actif anastrozol ou son hydrate, solvate ou sel physiologiquement acceptable dissous à une concentration de 0,1 % (m/m) à 30 % (m/m), sur la base du poids de la couche adhésive, et une couche pelliculable côté peau qui se retire du STT avant application. L'invention se rapporte aussi à l'utilisation de ce STT.
PCT/EP2008/058743 2007-07-10 2008-07-07 Systèmes thérapeutiques transdermiques contenant le principe actif anastrozol WO2009007334A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08774817A EP2178523A2 (fr) 2007-07-10 2008-07-07 Systèmes thérapeutiques transdermiques contenant le principe actif anastrozol

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710032468 DE102007032468A1 (de) 2007-07-10 2007-07-10 Transdermale Therapeutische Systeme, welche den Wirkstoff Anastrozol enthalten
DE102007032468.7 2007-07-10

Publications (2)

Publication Number Publication Date
WO2009007334A2 WO2009007334A2 (fr) 2009-01-15
WO2009007334A3 true WO2009007334A3 (fr) 2009-03-12

Family

ID=40121449

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/058743 WO2009007334A2 (fr) 2007-07-10 2008-07-07 Systèmes thérapeutiques transdermiques contenant le principe actif anastrozol

Country Status (3)

Country Link
EP (1) EP2178523A2 (fr)
DE (1) DE102007032468A1 (fr)
WO (1) WO2009007334A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010046464A1 (de) 2009-03-19 2011-04-21 Amw Gmbh Transdermales System mit Aromatasehemmer
DE102010026883A1 (de) 2010-03-11 2011-12-15 Amw Gmbh Transdermales System mit Aromatasehemmer
WO2017054151A1 (fr) * 2015-09-30 2017-04-06 徐静 Timbre pour application externe contenant de l'anastrozole et utilisation de celui-ci
DE102019110398A1 (de) * 2019-04-18 2020-10-22 Amw Gmbh Transdermales Darreichungssystem mit Aromatasehemmer
DE102019110397A1 (de) * 2019-04-18 2020-10-22 Amw Gmbh Transdermales Darreichungssystem mit Aromatasehemmer in übersättigter Matrix

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006788A1 (fr) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Administration trans-cutanee de vorozole
WO2002017928A2 (fr) * 2000-08-30 2002-03-07 Lts Lohman Therapie-Systeme Ag Systeme therapeutique transdermique destine a la delivrance d'exemestane
CN1927190A (zh) * 2006-09-28 2007-03-14 哈尔滨健迪医药技术有限公司 来曲唑透皮给药贴剂及其贴剂的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE505635C2 (sv) 1995-11-28 1997-09-22 Aga Ab Sätt och anordning för att tillsätta ett luktämne till ett ledningssystem för gas
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
EP0943333A1 (fr) 1998-03-18 1999-09-22 S.W. Patentverwertungs GmbH Médicament pour la prévention et/ou le traitement du cancer du sein contenant un inhibiteur de la synthèse d'estrogènes
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
EP1303270B1 (fr) * 2000-07-10 2006-03-29 Hormos Medical Ltd. Methode de traitement de la cryptorchidie
CA2492287C (fr) * 2002-07-12 2011-12-13 Pantarhei Bioscience B.V. Composition pharmaceutique comprenant des derives d'estetrol utilises dans la therapie anticancereuse
US20060189670A1 (en) * 2005-02-22 2006-08-24 Glenmark Pharmaceuticals Limited Process for the preparation of anastrozole and intermediates thereof
CA2626337C (fr) * 2005-10-19 2015-12-29 Chavah Pty Ltd Reduction des effets secondaires des inhibiteurs de l'aromatase employes dans le traitement du cancer du sein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006788A1 (fr) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Administration trans-cutanee de vorozole
WO2002017928A2 (fr) * 2000-08-30 2002-03-07 Lts Lohman Therapie-Systeme Ag Systeme therapeutique transdermique destine a la delivrance d'exemestane
CN1927190A (zh) * 2006-09-28 2007-03-14 哈尔滨健迪医药技术有限公司 来曲唑透皮给药贴剂及其贴剂的制备方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BUZDAR AMAN U; ROBERTSON JOHN F R; EIERMANN WOLFGANG; NABHOLTZ JEAN-MARC: "An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane.", CANCER, vol. 95, no. 9, 1 November 2002 (2002-11-01), United States, pages 2006 - 2016, XP002510617 *
DATABASE EPODOC EUROPEAN PATENT OFFICE, THE HAGUE, NL; XP002510618 *
SIPE ET AL: "A prospective randomized trial comparing anastrozole and clomiphene citrate in an ovulation induction protocol using gonadotropins", FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, NEW YORK, NY, US, vol. 86, no. 6, 22 November 2006 (2006-11-22), pages 1676 - 1681, XP005776229, ISSN: 0015-0282 *

Also Published As

Publication number Publication date
DE102007032468A1 (de) 2009-01-15
WO2009007334A2 (fr) 2009-01-15
EP2178523A2 (fr) 2010-04-28

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