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WO2009000384A2 - Système de contrôle de la prise de médicaments - Google Patents

Système de contrôle de la prise de médicaments Download PDF

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Publication number
WO2009000384A2
WO2009000384A2 PCT/EP2008/004360 EP2008004360W WO2009000384A2 WO 2009000384 A2 WO2009000384 A2 WO 2009000384A2 EP 2008004360 W EP2008004360 W EP 2008004360W WO 2009000384 A2 WO2009000384 A2 WO 2009000384A2
Authority
WO
WIPO (PCT)
Prior art keywords
rfid
cover film
blister
cover
patient
Prior art date
Application number
PCT/EP2008/004360
Other languages
German (de)
English (en)
Other versions
WO2009000384A3 (fr
Inventor
Michael Kiy
Original Assignee
Alcan Technology & Management Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcan Technology & Management Ltd. filed Critical Alcan Technology & Management Ltd.
Priority to EP08758929A priority Critical patent/EP2170243A2/fr
Publication of WO2009000384A2 publication Critical patent/WO2009000384A2/fr
Publication of WO2009000384A3 publication Critical patent/WO2009000384A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035Blister-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/06Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/32Layered products comprising a layer of synthetic resin comprising polyolefins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/02Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions
    • B32B3/08Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions characterised by added members at particular parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/13ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/30Compliance analysis for taking medication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00Properties of the layers or laminate
    • B32B2307/40Properties of the layers or laminate having particular optical properties
    • B32B2307/412Transparent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00Containers; Receptacles
    • B32B2439/80Medical packaging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2203/00Decoration means, markings, information elements, contents indicators
    • B65D2203/10Transponders

Definitions

  • the invention relates to a system for reminding a patient of a medication intake and checking the withdrawal of medication by the patient from a blister pack.
  • Known push-through or blister packs consist of a blister base part and a cover foil which is sealed against the blister bottom part and closes the pack.
  • a blister pack known for metered packaging of pharmaceutical products, such as tablets usually has a multiplicity of individual small containers in the form of cup-shaped depressions formed in the bottom blister in the blister bottom part for receiving the tablets. To remove a single tablet from a blister pack, the corresponding recess is pressed in the bottom part and in this case the tablet pushed through the lid material.
  • the cover sheet is an aluminum foil or a composite foil of an aluminum foil with further layers of plastic or paper.
  • the aluminum foil is a preferred lidding material for blister packs, since at the selected thicknesses of the lid materials relatively low breaking forces are necessary, the required piercing energy is thus low and the aluminum has a low elongation.
  • the bottom part of the blister pack made of plastic, such as PVC, polyamide, polyolefin, polyethylene terephthalate and from at least one of these materials constructed, optionally also containing an aluminum foil composite films.
  • plastic blister films wherein the blistering property of the plastic film is achieved by embedding fillers in the matrix.
  • the fillers are selected with regard to their composition and proportion in such a way that a weakening of the surrounding plastics occurs matrix, whereby the puncture resistance of the film is lowered so that the packaged goods can push through tearing or breaking the film through them. Due to the requirement that the selection of the fillers and in particular their proportions in the plastic matrix should ensure the puncture property of the film, opaque push-through films always resulted.
  • EP-A-0 613 832 discloses a metal foil-free cover sheet comprising at least one polyolefin or polyester-based thermoplastic film having a filler content of 5 to 50% by weight.
  • Preferred plastic is polyethylene
  • fillers are, for example, chalk and talc.
  • a transparent push-through foil with a polyolefin-containing polymer phase is known.
  • the polymer phase contains a hydrocarbon resin component in dissolved form with pendant cyclic groups on the polymer chain.
  • Preferred polyolefins are polyethylene, polypropylene or a co- or terpolymer of ethylene and / or propylene.
  • filler such as chalk or talc, may be embedded in the polymer composition.
  • a control, memory and motivation of patients can significantly increase the success of a therapy and thus lead to a reduction in costs.
  • All previous systems available on the market detect an opening of the packaging, which is also considered as taking the medication. If then the drug is really taken, can not be determined with most conventional systems. As a rule, however, a patient only bothers to open a package if he really wants to take the medication.
  • Some packages help the patient to take the medication by visibly displaying the time (e.g., days of the week) on the package from the outside.
  • Printed conductors arranged directly on the blister pack are disclosed, for example, in US Pat. No. 4,616,316, US Pat. No. 4,617,557, EP 0 972 507 A1, EP 0 129 785 A1 and US2007 / 0084746 A1.
  • the blister pack with the tracks are connected to dataloggers, which record every change of the contacts and record the time of the change. The data is usually read out at the end, thus controlling the time of taking it. Even systems without data output are known; they will issue warnings and instructions when not taking proper medication via a display.
  • a major disadvantage of the known systems are the required electronic components and batteries, which are usually for reasons of cost and lack of environmental compatibility no disposable items.
  • the use of mobile phones in memory of a medication intake is disclosed in DE 100 46 762 A1.
  • the invention has for its object to provide a system of the type mentioned, which allows reliable control of the drug intake without costly adaptation of the blister packs to the system and requires no electronic components and batteries to the blister pack.
  • a system which comprises:
  • a blister pack comprising a blister bottom portion having at least one container formed from a bottom film, containing a tablet or like medicament portion and a push-through cover film sealed against the blister bottom portion, an RFID tag associated with each receptacle and disposed over the container over the receptacle with an RFID tag; Chip with individual identification and a destroyed after opening the container RFI D antenna,
  • At least one RFID tag may have a writable RFID chip as reference RFI D tag.
  • the RFID reader is preferably arranged in a communication means with input and output means for receiving information and for transmitting information, the preferred communication means being a mobile telephone, in particular a mobile telephone with NFC technology.
  • the RFID antennas are printed on the cover sheet in the form of a Porterbahnaufdrucks.
  • the printed conductor imprint can be produced from a lacquer containing at least one electrically conductive material, wherein the electrically conductive material can be a powder of metal and / or graphite or an intrinsically conductive polymer.
  • Core of the invention is a novel detection mechanism for controlling the withdrawal of medication from the blister pack.
  • Complete RFI D tags consisting of one RFI D chip and one RFI D antenna per tablet are mounted in such a way that removing a tablet destroys the RFID antenna and thus makes this RFID tag illegible.
  • the other RFID tags remain functional, so that it can be reliably determined with an RFID reader, which tablet was removed.
  • RFID tags are usually passive systems, ie they are only active if there is sufficient electromagnetic radiation above the RFI D antenna in order to build up a sufficiently high operating voltage. Passive RFID tags therefore do not require a battery and are available on demand.
  • the RFID tags Upon activation, the RFID tags return information in the form of a number as an individual identification code to the RFI D reader. This number is unique, ie there is only one chip worldwide with this number. The numbers are usually 96 bit and allow about 8 x 10 28 different numbers. Furthermore, there are RFID chips that contain additional variable information, but these are relatively expensive.
  • the RFID antennas can not be directly applied to a metal surface as this would attenuate the electromagnetic radiation too much.
  • conventional aluminum foil as a cover film spacers would have to be provided, which, however, would significantly limit the compactness and function of the entire system.
  • a metal foil-free cover film as is known for example from DE 196 13 960 A1
  • the problem can be solved.
  • the known non-metallic cover films have the disadvantage of containing additives such as e.g. Talcum, exhibit. Without these additives, however, the brittleness of these films is too low for use as printable cover films.
  • the invention is therefore based on the further object of providing a metal foil-free cover film which is suitable for sealing against all common floor materials, which is transparent and at the same time has a brittleness which has comparable through-pressure properties with a conventional push-through film containing aluminum foil.
  • the cover film contains at least one layer of cycloolefin copolymer (COC).
  • Cycloolefin copolymer (COC) is a highly transparent material with excellent barrier to water vapor transmission, can be coextruded with other materials such as polyethylene or polypropylene, and is also very brittle. These properties provide ideal conditions for the use of cycloolefin copolymer (COC) for the production of push-through films. It is possible with this material fürdschreibfolien achieve with fürdrückfolien similar to the fürdschreibfolien produced in large quantities mainly from aluminum foil of a thickness of 20 microns.
  • the cover film is preferably provided in layers on the side facing against the blister side with a hot-sealing lacquer layer or a coextruded heat seal, the seal to blister base made of PVC, ACLAR ®, PP, PE, PS, Formpack ® or PA.
  • the cover sheet with a thermally stable at sealing temperature paint layer or with a coextruded, at sealing temperature thermally stable plastic layer preferably from COC, PP, PA or PET, be provided.
  • the cover film has a preferred thickness of 5 to 60 .mu.m, in particular 10 to 30 .mu.m.
  • the blister bottom part consists of a material whose chemical structure is compatible with that of the plastic film sealed against the blister bottom part.
  • Examples of materials used to make blister sheet parts are films of PVC, PVDC, PP, PET, PE, PS; PA and composite films such as PVC / ACLAR® (PCTFE), PVC / PVDC and COC or FORMPACK® (AI-AI BIister). It should be mentioned here that both the cover foil and the bottom foil can be printed.
  • the metal-free cover sheet according to the invention contains a multiplicity of RFID antennas, which are e.g. can be printed with silver on the cover sheet.
  • the cover film can already be equipped with the RFID chips already or later in the customer's process after the blister pack has been produced. For each blister pack, one RFI D antenna and one additional RFI D antenna in a non-destructible area are required per tablet.
  • the patient has received the blister pack, he can with a suitable RFID reader, which is preferably located in a mobile phone, read the reference RFI D-tag or another RFID tag, and the corresponding reading software thus knows the information (serial number ) about the drug.
  • the dosage may be, e.g. after sending the serial number of the blister pack by data transfer from a corresponding server.
  • the dosage can also be determined, for example, in a writable RFID chip by the pharmacy.
  • the information is preferably written in the reference RFI D chip, since this is present only once and thus the costs are lower.
  • the serial number can be used to verify the authenticity of the drug by comparing it with the manufacturer's database.
  • the software is now aware of the dosage and can begin to remind the patient of the medication according to a predetermined schedule. After taking the software asks to keep the example arranged in the mobile phone RFID reader to the blister pack so that the software can read the existing RFID chips there. Those RFIDs that no longer send information can be assigned to the removed tablets. The software saves the time and the Quantity / position of the removed tablets and can also forward this information directly online if required. This procedure is repeated at the next reminder.
  • FIG. 1 is a plan view of the Blisterteilteil a blister pack.
  • FIG. 2 shows a cross section through the blister pack of FIG. 1 along the line I-I;
  • - Fig. 3 is a plan view of the cover sheet of the blister pack of
  • FIG. 4 shows a cross section through a first cover sheet
  • FIG. FIG. 5 shows a cross section through a second cover film
  • FIG. 6 shows a system for controlling a medication intake.
  • a blister pack 10 shown in Figs. 1 to 3 consists of a Blisterteil 12 formed out of a bottom foil, cup-shaped containers 14.
  • the containers 14 are tablets 16.
  • As a closure for the containers 14 is a the openings of the containers 14 spanning cover sheet 18 sealed against the blister base 12.
  • the cover film 18 is equipped with RFID tags 70 with an RFID chip 72 and an RFID antenna 74, wherein over the opening of each container 14 of the Blister foundedteils 12 each an RFID tag 70 is arranged.
  • a reference RFI D tag 70 a is arranged in a non-destructible area.
  • a first cover film 18 shown by way of example in FIG. 4 consists of a core film 20 of mLLDPE (metallocene-based linear polyethylene lower
  • Heissgueellack für 26 has a thickness of 2 microns, optionally provided with an imprinted outside with a transparent protective lacquer layer 28 of a thickness of 2 microns.
  • a second embodiment of a cover film 18 shown by way of example in FIG. 5 consists of a core film 30 made of COC with a thickness of 10 .mu.m and films of 5 .mu.m thickness coextruded on both sides.
  • a system shown in FIG. 6 by way of example for controlling a medicament intake or a removal of a tablet 16 from a blister pack 10 comprises a mobile telephone 42 for receiving and transmitting information, eg in the form of SMS (Short Message Service) short message.
  • a mobile radio network 44 for example a GSM (Global System for Mobile Communications) or a UMTS (Universal Mobile Telecommunications System) mobile radio network or another mobile radio network, for example a satellite-based mobile radio network or a WLAN (Wireless Local Area Network).
  • GSM Global System for Mobile Communications
  • UMTS Universal Mobile Telecommunications System
  • WLAN Wireless Local Area Network
  • the system further comprises a computer system 46 having a transceiver unit 48 for transmitting and receiving information over the cellular network 44, a computer unit 50, and a database 52 associated with the computer unit 50 with the stored data including instructions for a patient to take the medication Identification 40 of the blister packs 10th LIST OF REFERENCES

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Primary Health Care (AREA)
  • Composite Materials (AREA)
  • Mechanical Engineering (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un système destiné à rappeler à un patient la prise de médicaments et à vérifier la prise de médicaments par le patient par prélèvement dans un emballage sous blister (10). Le système comprend : un emballage sous blister (10) présentant une partie fond de blister (12), au moins un contenant (14) formé à partir d'un film de fond et dans lequel se trouve un comprimé (16) ou une dose médicamenteuse analogue, et un film de recouvrement (18) extrudable scellé contre la partie fond de blister (12); une étiquette RFID (70) associée à chaque contenant (14), disposée sur le film de recouvrement (18) au dessus du contenant (14) et comprenant une puce RFID (72) à caractéristique d'identification (40) individuelle et une antenne RFID (74) qui est détruite après ouverture du contenant (14); un lecteur RFID associé au patient et destiné à reconnaître des étiquettes RFID (70) non détruites; et un logiciel associé au lecteur RFID et comprenant une unité d'enregistrement destinée à la lecture et à l'enregistrement de données comprenant des instructions renseignant le patient sur la prise des médicaments et les caractéristiques d'identification (40) de l'emballage sous blister (10).
PCT/EP2008/004360 2007-06-22 2008-06-02 Système de contrôle de la prise de médicaments WO2009000384A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08758929A EP2170243A2 (fr) 2007-06-22 2008-06-02 Système de contrôle de la prise de médicaments

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH01003/07 2007-06-22
CH10032007 2007-06-22

Publications (2)

Publication Number Publication Date
WO2009000384A2 true WO2009000384A2 (fr) 2008-12-31
WO2009000384A3 WO2009000384A3 (fr) 2009-02-19

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013109221A1 (de) * 2013-08-26 2015-02-26 Infineon Technologies Ag Chip-Anordnung, Analysevorrichtung, Aufnahmebehälter, und Aufnahmebehältersystem
EP3149718A4 (fr) * 2014-05-27 2018-01-31 Amerisourcebergen Specialty Group, Inc. Système et procédé de distribution et de suivi de produits
US10588826B2 (en) 2014-11-04 2020-03-17 Intelligent Devices Sezc Inc. Means for monitoring compliance, facilitating automatic dispensing and childproofing strip packaged medications

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WO1997014157A1 (fr) * 1995-10-07 1997-04-17 Img Group Limited Composant de circuit electrique forme par impression directe d'un liquide conducteur sur un substrat
DE10046762A1 (de) * 1999-10-23 2001-05-23 Siegfried R Riek Handy mit Schnittstelle zur Kommunikation mit einer interaktiven Schaltung mit welcher Medikamente virtuell verwaltet und über ein Signal zur Einnahme gemeldet werden können
WO2001051369A1 (fr) * 2000-01-10 2001-07-19 Moore North America, Inc. Etiquettes a frequence radio situees sur des contenants a usages multiples
US20030063524A1 (en) * 2000-07-07 2003-04-03 Niemiec Mark A. Drug delivery management system
WO2006007867A1 (fr) * 2004-07-20 2006-01-26 Schreiner Group Gmbh & Co. Kg Plaquette de support de produits
DE202005017891U1 (de) * 2005-10-12 2006-11-16 Alcan Technology & Management Ag Kaltverformbares Laminat für Bodenteile von Blisterverpackungen
WO2007043858A2 (fr) * 2005-09-02 2007-04-19 Kort, Willem, Theo Plaquette alveolaire dotee d'un systeme de surveillance de contenu (otcm) a composants electroniques polymeres imprimes
WO2007060588A1 (fr) * 2005-11-23 2007-05-31 Koninklijke Philips Electronics N.V. Systeme de controle d’un distributeur de medicament

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014157A1 (fr) * 1995-10-07 1997-04-17 Img Group Limited Composant de circuit electrique forme par impression directe d'un liquide conducteur sur un substrat
DE10046762A1 (de) * 1999-10-23 2001-05-23 Siegfried R Riek Handy mit Schnittstelle zur Kommunikation mit einer interaktiven Schaltung mit welcher Medikamente virtuell verwaltet und über ein Signal zur Einnahme gemeldet werden können
WO2001051369A1 (fr) * 2000-01-10 2001-07-19 Moore North America, Inc. Etiquettes a frequence radio situees sur des contenants a usages multiples
US20030063524A1 (en) * 2000-07-07 2003-04-03 Niemiec Mark A. Drug delivery management system
WO2006007867A1 (fr) * 2004-07-20 2006-01-26 Schreiner Group Gmbh & Co. Kg Plaquette de support de produits
WO2007043858A2 (fr) * 2005-09-02 2007-04-19 Kort, Willem, Theo Plaquette alveolaire dotee d'un systeme de surveillance de contenu (otcm) a composants electroniques polymeres imprimes
DE202005017891U1 (de) * 2005-10-12 2006-11-16 Alcan Technology & Management Ag Kaltverformbares Laminat für Bodenteile von Blisterverpackungen
WO2007060588A1 (fr) * 2005-11-23 2007-05-31 Koninklijke Philips Electronics N.V. Systeme de controle d’un distributeur de medicament

Cited By (5)

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