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WO2009093251A3 - Vaccin contenant un réovirus basé sur une séquence de protéine sigma c - Google Patents

Vaccin contenant un réovirus basé sur une séquence de protéine sigma c Download PDF

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Publication number
WO2009093251A3
WO2009093251A3 PCT/IL2009/000098 IL2009000098W WO2009093251A3 WO 2009093251 A3 WO2009093251 A3 WO 2009093251A3 IL 2009000098 W IL2009000098 W IL 2009000098W WO 2009093251 A3 WO2009093251 A3 WO 2009093251A3
Authority
WO
WIPO (PCT)
Prior art keywords
sigma
protein sequence
vaccine based
peptide
reovirus
Prior art date
Application number
PCT/IL2009/000098
Other languages
English (en)
Other versions
WO2009093251A2 (fr
Inventor
Jacob Pitcovski
Dana Goldenberg
Original Assignee
Gavish-Galilee Bio Applications Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gavish-Galilee Bio Applications Ltd filed Critical Gavish-Galilee Bio Applications Ltd
Publication of WO2009093251A2 publication Critical patent/WO2009093251A2/fr
Publication of WO2009093251A3 publication Critical patent/WO2009093251A3/fr
Priority to IL207196A priority Critical patent/IL207196A0/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un peptide dérivé d’une région conservée d’une protéine sigma C d’un isolat de réovirus aviaire, et un analogue dudit peptide, ainsi que des vaccins anti-réovirus à large spectre d’activité contenant ledit peptide.
PCT/IL2009/000098 2008-01-24 2009-01-25 Vaccin contenant un réovirus basé sur une séquence de protéine sigma c WO2009093251A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL207196A IL207196A0 (en) 2008-01-24 2010-07-25 Reovirus vaccine based on sigma c protein sequence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2314608P 2008-01-24 2008-01-24
US61/023,146 2008-01-24

Publications (2)

Publication Number Publication Date
WO2009093251A2 WO2009093251A2 (fr) 2009-07-30
WO2009093251A3 true WO2009093251A3 (fr) 2009-10-22

Family

ID=40848562

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/000098 WO2009093251A2 (fr) 2008-01-24 2009-01-25 Vaccin contenant un réovirus basé sur une séquence de protéine sigma c

Country Status (1)

Country Link
WO (1) WO2009093251A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101600959B1 (ko) * 2013-06-18 2016-03-08 단국대학교 산학협력단 가금 레오바이러스 시그마 c 단백질의 항원 결정기를 포함하는 재조합 단백질 및 이에 대한 항체
RU2708316C2 (ru) 2014-01-29 2019-12-05 Дзе Юниверсити Оф Джорджиа Рисерч Фаундейшн, Инк. Вакцины на основе реовирусов птиц
ES2954910T3 (es) 2014-10-03 2023-11-27 Intervet Int Bv Vacuna de amplio espectro contra el reovirus aviar
RU2742250C2 (ru) * 2016-01-07 2021-02-04 Гавиш-Галили Био Эпликейшнз, Лтд Оптимизированный полипептид для субъединичной вакцины против реовируса птиц
CN116120468B (zh) * 2023-03-16 2023-09-08 扬州优邦生物药品有限公司 一种预防禽呼肠孤病毒的病毒样颗粒疫苗及其制备方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001809A (en) * 1994-07-11 1999-12-14 Elan Pharmaceuticals, Inc. Inhibitors of leukocyte adhesion
WO2000037487A1 (fr) * 1998-12-19 2000-06-29 Merck Patent Gmbh INHIBITEURS DE L'INTEGRINE $G(a)v$G(b)¿6?
US6187548B1 (en) * 1993-05-23 2001-02-13 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods using human calcium sensor protein, fragments thereof and DNA encoding same
US6239270B1 (en) * 1993-05-24 2001-05-29 Rhone-Poulenc Rorer S.A. Nucleic acids encoding human calcium sensor protein
WO2001096377A2 (fr) * 2000-06-15 2001-12-20 Purdue Research Foundation Vaccin contre les tremblements congenitaux du porc
US6689363B1 (en) * 1992-01-29 2004-02-10 Epimmune Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
WO2004031211A2 (fr) * 2002-10-03 2004-04-15 Epimmune Inc. Peptides de liaison hla et utilisations de ces derniers
WO2005110456A2 (fr) * 2004-05-11 2005-11-24 Abgenomics Corporation Epitopes induisant la mort des lymphocytes t
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689363B1 (en) * 1992-01-29 2004-02-10 Epimmune Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
US6187548B1 (en) * 1993-05-23 2001-02-13 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods using human calcium sensor protein, fragments thereof and DNA encoding same
US6239270B1 (en) * 1993-05-24 2001-05-29 Rhone-Poulenc Rorer S.A. Nucleic acids encoding human calcium sensor protein
US6001809A (en) * 1994-07-11 1999-12-14 Elan Pharmaceuticals, Inc. Inhibitors of leukocyte adhesion
WO2000037487A1 (fr) * 1998-12-19 2000-06-29 Merck Patent Gmbh INHIBITEURS DE L'INTEGRINE $G(a)v$G(b)¿6?
US7026443B1 (en) * 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
WO2001096377A2 (fr) * 2000-06-15 2001-12-20 Purdue Research Foundation Vaccin contre les tremblements congenitaux du porc
WO2004031211A2 (fr) * 2002-10-03 2004-04-15 Epimmune Inc. Peptides de liaison hla et utilisations de ces derniers
WO2005110456A2 (fr) * 2004-05-11 2005-11-24 Abgenomics Corporation Epitopes induisant la mort des lymphocytes t

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HSU CHIEN J ET AL: "Development and characterization of monoclonal antibodies against avian reovirus .sigma.C protein and their application in detection of avian reovirus isolates", AVIAN PATHOLOGY, HUNTINGDON, CAMBS, GB, vol. 35, no. 4, 1 August 2006 (2006-08-01), pages 320 - 326, XP008107192, ISSN: 0307-9457 *
VASSERMAN Y ET AL: "The influence of reovirus sigma C protein diversity on vaccination efficiency", AVIAN DISEASES, AMERICAN ASSOCIATION OF AVIAN PATHOLOGISTS, KENNET SQ., PA, US, vol. 48, no. 2, 1 April 2004 (2004-04-01), pages 271 - 278, XP008107191, ISSN: 0005-2086 *

Also Published As

Publication number Publication date
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