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WO2009085575A3 - Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof - Google Patents

Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof Download PDF

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Publication number
WO2009085575A3
WO2009085575A3 PCT/US2008/085841 US2008085841W WO2009085575A3 WO 2009085575 A3 WO2009085575 A3 WO 2009085575A3 US 2008085841 W US2008085841 W US 2008085841W WO 2009085575 A3 WO2009085575 A3 WO 2009085575A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
calibrator
quality control
immunohistochemistry assay
cell device
Prior art date
Application number
PCT/US2008/085841
Other languages
French (fr)
Other versions
WO2009085575A2 (en
Inventor
Marc E. Key
Original Assignee
Spring Bioscience Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spring Bioscience Corporation filed Critical Spring Bioscience Corporation
Publication of WO2009085575A2 publication Critical patent/WO2009085575A2/en
Publication of WO2009085575A3 publication Critical patent/WO2009085575A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

This disclosure relates to immunohistochemistry, and specifically to a quality control device for an immunohistochemistry assay and methods of use thereof. More specifically, disclosed herein is a calibrator cell pellet and methods of use as a control in an immunohistochemistry assay. The calibrator cell pellets are used, in some embodiments, as standards for quantifying the intensity of immunohistochemical staining, for instance for normalizing immunohistochemical staining to a calibrated standard, thereby allowing more accurate quantitation of staining intensity.
PCT/US2008/085841 2007-12-28 2008-12-08 Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof WO2009085575A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US936007P 2007-12-28 2007-12-28
US942007P 2007-12-28 2007-12-28
US942607P 2007-12-28 2007-12-28
US61/009,360 2007-12-28
US61/009,420 2007-12-28
US61/009,426 2007-12-28

Publications (2)

Publication Number Publication Date
WO2009085575A2 WO2009085575A2 (en) 2009-07-09
WO2009085575A3 true WO2009085575A3 (en) 2009-09-17

Family

ID=40824978

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2008/085833 WO2009085573A2 (en) 2007-12-28 2008-12-08 Quality control cell device for immunohistochemistry assay and methods of use thereof
PCT/US2008/085844 WO2009085576A2 (en) 2007-12-28 2008-12-08 Positive control cell pellets for immunohistochemistry and methods of use thereof
PCT/US2008/085841 WO2009085575A2 (en) 2007-12-28 2008-12-08 Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2008/085833 WO2009085573A2 (en) 2007-12-28 2008-12-08 Quality control cell device for immunohistochemistry assay and methods of use thereof
PCT/US2008/085844 WO2009085576A2 (en) 2007-12-28 2008-12-08 Positive control cell pellets for immunohistochemistry and methods of use thereof

Country Status (1)

Country Link
WO (3) WO2009085573A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2742743C2 (en) 2010-03-12 2021-02-10 Дебиофарм Интернешнл, С.А. Cd37-binding molecules and their immunoconjugates
US9447189B2 (en) 2011-04-01 2016-09-20 Immunogen, Inc. CD37-binding molecules and immunoconjugates thereof
JP2015514716A (en) * 2012-03-30 2015-05-21 イミュノジェン， インコーポレイテッド Method for increasing the effectiveness of a treatment based on CD37
US20130338014A1 (en) * 2012-04-05 2013-12-19 Vala Sciences, Inc. Calibration Standards For Digital Histocytometry
US20130338016A1 (en) * 2012-04-17 2013-12-19 Vala Sciences, Inc. Method For Integrated Pathology Diagnosis And Digital Biomarker Pattern Analysis
WO2014052876A1 (en) * 2012-09-28 2014-04-03 Immunogen Inc. Methods for increasing efficacy of cd56- based therapy
SG11201508139UA (en) * 2013-03-30 2015-11-27 Clarient Diagnostic Services Inc Microscope slides with quality controls thereon
EP3027226A4 (en) * 2013-08-02 2016-07-27 Siemens Healthcare Diagnostics CELLS WITNESSES AND ASSOCIATED METHOD
KR20180011315A (en) 2015-06-08 2018-01-31 데비오팜 인터네셔날 에스 에이 Anti-cd37 immunoconjugate and anti-cd20 antibody combinations
MX2018002467A (en) 2015-08-28 2018-06-15 Debiopharm Int Sa Antibodies and assays for detection of cd37.
CN105241726A (en) * 2015-09-14 2016-01-13 黄小军 Immunohistochemical staining method and applications of immunohistochemical staining method in cervical tumorous lesion screening
US11278629B2 (en) 2016-11-02 2022-03-22 Debiopharm International, S.A. Methods for improving anti-CD37 immunoconjugate therapy
EP3639079A4 (en) * 2017-06-15 2021-02-24 Sunstone Scientific Limited. Process record slide for immunohistochemical staining
KR102342988B1 (en) * 2017-06-15 2021-12-27 션전 피알에스 리미티드 IHC antigen imaging scale extrapolation method
KR20210014684A (en) 2018-05-30 2021-02-09 데비오팜 인터네셔날 에스 에이 Anti-CD37 immunoconjugate dosage regimen
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
GB202006257D0 (en) * 2020-04-28 2020-06-10 Leeds Teaching Hospitals Nhs Trust Stain assessment
CN113515077A (en) * 2021-04-23 2021-10-19 重庆德方信息技术有限公司 System and method for monitoring human body cell staining process
GB2630694B (en) * 2021-05-06 2025-04-30 Futamura Chemical Uk Ltd Device
GB2606387B (en) * 2021-05-06 2024-08-14 Futamura Chemical Uk Ltd Device
CN117295946A (en) * 2021-06-07 2023-12-26 株式会社日立高新技术 Control slide for pathological examination and method for manufacturing same
CN113820286A (en) * 2021-09-27 2021-12-21 麦克奥迪（厦门）医疗诊断系统有限公司 Chip and calibration method for DNA ploidy analysis system calibration
CN116026654A (en) * 2022-12-30 2023-04-28 江苏鼎泰药物研究(集团)股份有限公司 Method for preparing immunohistochemical positive control tissue section
CN118376792B (en) * 2024-04-16 2025-04-15 北京菲诺维康生物科技有限公司 A calibration method for detecting tissue target protein expression results

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005263A1 (en) * 1989-09-26 1991-04-18 City Of Hope Quantitative immunocytochemistry assay
US5846749A (en) * 1994-10-12 1998-12-08 The Regents Of The University Of California Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination
WO2000062064A2 (en) * 1999-04-14 2000-10-19 Cytologix Corporation Quality control for cytochemical assays
US20050003458A1 (en) * 2003-06-12 2005-01-06 Mathew Moore Method and system for the analysis of high density cells samples
KR100650162B1 (en) * 2003-08-05 2006-11-27 주식회사 진인 Microarray for detecting drug-resistant hepatitis virus containing a quality control probe and a negative control probe and a method for detecting drug-resistant hepatitis virus using the same
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005263A1 (en) * 1989-09-26 1991-04-18 City Of Hope Quantitative immunocytochemistry assay
US5846749A (en) * 1994-10-12 1998-12-08 The Regents Of The University Of California Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination
WO2000062064A2 (en) * 1999-04-14 2000-10-19 Cytologix Corporation Quality control for cytochemical assays
US20050003458A1 (en) * 2003-06-12 2005-01-06 Mathew Moore Method and system for the analysis of high density cells samples
KR100650162B1 (en) * 2003-08-05 2006-11-27 주식회사 진인 Microarray for detecting drug-resistant hepatitis virus containing a quality control probe and a negative control probe and a method for detecting drug-resistant hepatitis virus using the same
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls

Also Published As

Publication number Publication date
WO2009085576A3 (en) 2009-09-24
WO2009085575A2 (en) 2009-07-09
WO2009085576A2 (en) 2009-07-09
WO2009085573A3 (en) 2009-09-17
WO2009085573A2 (en) 2009-07-09

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