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WO2009068250A8 - Drug delivery device with shape memory actuator, lead screw and ratchet mechanism - Google Patents

Drug delivery device with shape memory actuator, lead screw and ratchet mechanism Download PDF

Info

Publication number
WO2009068250A8
WO2009068250A8 PCT/EP2008/009999 EP2008009999W WO2009068250A8 WO 2009068250 A8 WO2009068250 A8 WO 2009068250A8 EP 2008009999 W EP2008009999 W EP 2008009999W WO 2009068250 A8 WO2009068250 A8 WO 2009068250A8
Authority
WO
WIPO (PCT)
Prior art keywords
lead screw
shape memory
delivery device
drug delivery
memory alloy
Prior art date
Application number
PCT/EP2008/009999
Other languages
French (fr)
Other versions
WO2009068250A1 (en
Inventor
Marco. C. De Polo
Christopher Wiegel
Steven N. Roe
Original Assignee
Roche Diagnostics Gmbh
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, F. Hoffmann-La Roche Ag filed Critical Roche Diagnostics Gmbh
Priority to EP08855618.8A priority Critical patent/EP2211939B1/en
Priority to DK08855618.8T priority patent/DK2211939T3/en
Publication of WO2009068250A1 publication Critical patent/WO2009068250A1/en
Publication of WO2009068250A8 publication Critical patent/WO2009068250A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03G—SPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
    • F03G7/00—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
    • F03G7/06—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
    • F03G7/061—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by the actuating element
    • F03G7/0614—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by the actuating element using shape memory elements
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03G—SPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
    • F03G7/00—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
    • F03G7/06—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
    • F03G7/061—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by the actuating element
    • F03G7/0614—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by the actuating element using shape memory elements
    • F03G7/06143—Wires
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03G—SPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
    • F03G7/00—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
    • F03G7/06—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
    • F03G7/062—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by the activation arrangement
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03G—SPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
    • F03G7/00—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
    • F03G7/06—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
    • F03G7/064—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by its use
    • F03G7/0646—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like characterised by its use for pumping or compressing fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266—Shape memory materials

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Transmission Devices (AREA)

Abstract

A drug delivery device drive (100) that includes a single shape memory alloy wire actuator (10) to advance a lead screw (14) via a ratcheting mechanism is disclosed. In one embodiment, a shape memory alloy wire (10) is operably connected to one of a pair of ratchet wheels (16, 18) and configured to drive incrementally the rotation of the connected ratchet wheel (18) via a contraction, which in turn drives the rotation of the other ratchet wheel (16) about a rotational axis (X) which moves a lead screw and advances a plunger (48) to dispense a liquid drug from a drug container (50). A drug delivery device using the shape memory alloy wire actuator in combination with the ratcheting mechanism to incrementally rotate a shaft, a lead screw or a sleeve provides for a more compact and less complicated design.
PCT/EP2008/009999 2007-11-29 2008-11-26 Drug delivery device with shape memory actuator, lead screw and ratchet mechanism WO2009068250A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP08855618.8A EP2211939B1 (en) 2007-11-29 2008-11-26 Drug delivery device with shape memory actuator, lead screw and ratchet mechanism
DK08855618.8T DK2211939T3 (en) 2007-11-29 2008-11-26 PHARMACEUTICAL DELIVERY DEVICE WITH MEMORIAL MEMORY ACTUATOR, SCREW SCREW AND REMOVAL

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/946,905 2007-11-29
US11/946,905 US7771392B2 (en) 2007-11-29 2007-11-29 Lead screw delivery device using reusable shape memory actuator drive

Publications (2)

Publication Number Publication Date
WO2009068250A1 WO2009068250A1 (en) 2009-06-04
WO2009068250A8 true WO2009068250A8 (en) 2010-05-27

Family

ID=40385903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/009999 WO2009068250A1 (en) 2007-11-29 2008-11-26 Drug delivery device with shape memory actuator, lead screw and ratchet mechanism

Country Status (4)

Country Link
US (1) US7771392B2 (en)
EP (1) EP2211939B1 (en)
DK (1) DK2211939T3 (en)
WO (1) WO2009068250A1 (en)

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Also Published As

Publication number Publication date
WO2009068250A1 (en) 2009-06-04
DK2211939T3 (en) 2019-04-01
US20090143730A1 (en) 2009-06-04
EP2211939B1 (en) 2018-12-19
EP2211939A1 (en) 2010-08-04
US7771392B2 (en) 2010-08-10

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