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WO2009066537A1 - 免疫調節性機能誘導剤及び食品組成物 - Google Patents

免疫調節性機能誘導剤及び食品組成物 Download PDF

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Publication number
WO2009066537A1
WO2009066537A1 PCT/JP2008/069210 JP2008069210W WO2009066537A1 WO 2009066537 A1 WO2009066537 A1 WO 2009066537A1 JP 2008069210 W JP2008069210 W JP 2008069210W WO 2009066537 A1 WO2009066537 A1 WO 2009066537A1
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WO
WIPO (PCT)
Prior art keywords
lactic acid
acid bacterium
processed product
bacterium
food composition
Prior art date
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PCT/JP2008/069210
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English (en)
French (fr)
Inventor
Seiya Makino
Shuji Ikegami
Noriko Tsuji
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Meiji Dairies Corporation
National Institute Of Advanced Industrial Science And Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Meiji Dairies Corporation, National Institute Of Advanced Industrial Science And Technology filed Critical Meiji Dairies Corporation
Priority to JP2009542511A priority Critical patent/JP5527690B2/ja
Publication of WO2009066537A1 publication Critical patent/WO2009066537A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

　炎症性腸疾患に対して抗炎症効果の高いラクトコッカス属乳酸菌を提供することを課題とする。 　主にラクトコッカス・ラクティスＯＬＳ３３０１（Ｌａｃｔｏｃｏｃｃｕｓ　ｌａｃｔｉｓ　ＯＬＳ３３０１）株等を代表とするラクトコッカス属乳酸菌及び／又はその処理物、これを有効成分とする免疫調節性機能誘導剤、及びこれを有効量含んでなる食品組成物を提供する。本発明の菌及び／又はその処理物は抗炎症性のサイトカインであるＩＬ－１０を免疫担当細胞に大量に産生させる能力を有するので、過剰な炎症応答による炎症を抑制することができる。さらに、皮膚における炎症を抑制することもできる。
PCT/JP2008/069210 2007-11-19 2008-10-23 免疫調節性機能誘導剤及び食品組成物 WO2009066537A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009542511A JP5527690B2 (ja) 2007-11-19 2008-10-23 免疫調節性機能誘導剤及び食品組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007298754 2007-11-19
JP2007-298754 2007-11-19

Publications (1)

Publication Number Publication Date
WO2009066537A1 true WO2009066537A1 (ja) 2009-05-28

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PCT/JP2008/069210 WO2009066537A1 (ja) 2007-11-19 2008-10-23 免疫調節性機能誘導剤及び食品組成物

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JP (1) JP5527690B2 (ja)
WO (1) WO2009066537A1 (ja)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148710A (ja) * 2010-01-19 2011-08-04 Snow Brand Milk Prod Co Ltd 炎症性腸疾患及び／又は過敏性腸症候群の予防及び／又は治療剤
JP2014501100A (ja) * 2010-12-17 2014-01-20 コンパニ・ジェルベ・ダノン 消化器の病的状態の改善に使用するためのラクトコッカスラクティス株
JP6298912B1 (ja) * 2017-04-10 2018-03-20 有限会社バイオ研 乳酸菌の製造方法、及び免疫調節用組成物
WO2018092678A1 (ja) * 2016-11-16 2018-05-24 株式会社明治 微生物の加熱処理方法
KR102154254B1 (ko) * 2020-04-29 2020-09-09 (주)녹십자웰빙 우수한 면역기능 증진 효과를 갖는 신규한 유산균 및 이를 포함하는 식품조성물, 건강기능성 식품 조성물 및 프로바이오틱스
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
CN111818812A (zh) * 2018-03-15 2020-10-23 麒麟控股株式会社 皮肤状态改善用组合物
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11466582B2 (en) 2016-10-12 2022-10-11 General Electric Company Turbine engine inducer assembly
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
CN116121110A (zh) * 2022-10-28 2023-05-16 益加生物科技成都有限公司 一种抑菌和抗炎作用较强的乳酸乳球菌yj0801及其应用
WO2025018275A1 (ja) * 2023-07-14 2025-01-23 株式会社明治 ラクトコッカス属乳酸菌及びその発酵物を含む組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005154387A (ja) * 2003-11-28 2005-06-16 National Institute Of Agrobiological Sciences 免疫調節性機能を誘導する乳酸菌類・成分とその取得方法
JP2007269737A (ja) * 2006-03-31 2007-10-18 Morinaga Milk Ind Co Ltd インターロイキン産生調節剤、該インターロイキン産生調節剤を含む医薬組成物及び飲食品、並びにその製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005154387A (ja) * 2003-11-28 2005-06-16 National Institute Of Agrobiological Sciences 免疫調節性機能を誘導する乳酸菌類・成分とその取得方法
JP2007269737A (ja) * 2006-03-31 2007-10-18 Morinaga Milk Ind Co Ltd インターロイキン産生調節剤、該インターロイキン産生調節剤を含む医薬組成物及び飲食品、並びにその製造方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HIROMI KIMOTO ET AL.: "Nyugyoyo Nyusankin Lactococcus no Men'eki Chosetsu Sayo ni tsuite", JOURNALOF JAPANESE SOCIETY OF NUTRITION, AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 58TH, 2004, pages 123 *
MAKINO S. ET AL.: "Immunomodulatory efects of Lactococcus lactis subsp. lactis OLS3301 on dextran sulfate sodium-induced colitis in mice.", DAI 37 KAI PROCEEDINGS OF THE JAPANESE SOCIETY FOR IMMUNOLOGY, vol. 37, October 2007 (2007-10-01), pages 161 *
NORIKO TSUJI ET AL.: "IL-10 Sansei o Unagashi Men'eki Chosetsu ni Hataraku Probiotics", NIPPON NOGEI KAGAKUKAI TAIKAI KOEN YOSHISHU, vol. 2004, 2004, pages 217 *

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148710A (ja) * 2010-01-19 2011-08-04 Snow Brand Milk Prod Co Ltd 炎症性腸疾患及び／又は過敏性腸症候群の予防及び／又は治療剤
JP2014501100A (ja) * 2010-12-17 2014-01-20 コンパニ・ジェルベ・ダノン 消化器の病的状態の改善に使用するためのラクトコッカスラクティス株
US10874700B2 (en) 2016-03-31 2020-12-29 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US11998575B2 (en) 2016-03-31 2024-06-04 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US11633451B2 (en) 2016-03-31 2023-04-25 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
US11846209B2 (en) 2016-10-12 2023-12-19 General Electric Company Turbine engine inducer assembly
US11466582B2 (en) 2016-10-12 2022-10-11 General Electric Company Turbine engine inducer assembly
WO2018092678A1 (ja) * 2016-11-16 2018-05-24 株式会社明治 微生物の加熱処理方法
JP2018078832A (ja) * 2016-11-16 2018-05-24 株式会社明治 微生物の加熱処理方法
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
JP2018174772A (ja) * 2017-04-10 2018-11-15 有限会社バイオ研 乳酸菌の製造方法、及び免疫調節用組成物
JP6298912B1 (ja) * 2017-04-10 2018-03-20 有限会社バイオ研 乳酸菌の製造方法、及び免疫調節用組成物
EP3766363A4 (en) * 2018-03-15 2022-01-05 Kirin Holdings Kabushiki Kaisha COMPOSITION TO IMPROVE SKIN PROBLEMS
US11497778B2 (en) 2018-03-15 2022-11-15 Kirin Holdings Kabushiki Kaisha Composition for improving skin conditions
CN111818812B (zh) * 2018-03-15 2023-09-26 麒麟控股株式会社 皮肤状态改善用组合物
CN111818812A (zh) * 2018-03-15 2020-10-23 麒麟控股株式会社 皮肤状态改善用组合物
AU2019233471B2 (en) * 2018-03-15 2024-03-28 Kirin Holdings Kabushiki Kaisha Composition for improving skin conditions
KR102154254B1 (ko) * 2020-04-29 2020-09-09 (주)녹십자웰빙 우수한 면역기능 증진 효과를 갖는 신규한 유산균 및 이를 포함하는 식품조성물, 건강기능성 식품 조성물 및 프로바이오틱스
CN116121110A (zh) * 2022-10-28 2023-05-16 益加生物科技成都有限公司 一种抑菌和抗炎作用较强的乳酸乳球菌yj0801及其应用
WO2025018275A1 (ja) * 2023-07-14 2025-01-23 株式会社明治 ラクトコッカス属乳酸菌及びその発酵物を含む組成物

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JPWO2009066537A1 (ja) 2011-04-07
JP5527690B2 (ja) 2014-06-18

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