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WO2009066469A1 - 被験物測定用担体およびその製造方法 - Google Patents

被験物測定用担体およびその製造方法 Download PDF

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Publication number
WO2009066469A1
WO2009066469A1 PCT/JP2008/003434 JP2008003434W WO2009066469A1 WO 2009066469 A1 WO2009066469 A1 WO 2009066469A1 JP 2008003434 W JP2008003434 W JP 2008003434W WO 2009066469 A1 WO2009066469 A1 WO 2009066469A1
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WO
WIPO (PCT)
Prior art keywords
reactant
analyte
carrier
site
measurement
Prior art date
Application number
PCT/JP2008/003434
Other languages
English (en)
French (fr)
Inventor
Koichi Minami
Hirohiko Tsuzuki
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Priority to US12/744,311 priority Critical patent/US8236575B2/en
Priority to EP08851758.6A priority patent/EP2224241B1/en
Publication of WO2009066469A1 publication Critical patent/WO2009066469A1/ja

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

【課題】被験物測定用担体を、被験物を短時間で、高感度かつ簡便に検出することができるものとする。 【解決手段】被験物と特異的に結合する反応部位（２）および蛍光標識部位（３）を有する第１反応体（４）と、被験物と特異的に結合する反応部位（５）および前記第１反応体（４）の蛍光標識部位（３）から発せられる蛍光を認識する認識部位（６）を有する第２反応体（７）とを、それぞれ被験物と結合し得る位置関係で担体上に固定されているものとする。
PCT/JP2008/003434 2007-11-22 2008-11-21 被験物測定用担体およびその製造方法 WO2009066469A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/744,311 US8236575B2 (en) 2007-11-22 2008-11-21 Carrier for analysis of an analyte and process for producing the same
EP08851758.6A EP2224241B1 (en) 2007-11-22 2008-11-21 Carrier for use in measurement of analyte, and method for production thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-303026 2007-11-22
JP2007303026 2007-11-22

Publications (1)

Publication Number Publication Date
WO2009066469A1 true WO2009066469A1 (ja) 2009-05-28

Family

ID=40667301

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003434 WO2009066469A1 (ja) 2007-11-22 2008-11-21 被験物測定用担体およびその製造方法

Country Status (4)

Country Link
US (1) US8236575B2 (ja)
EP (1) EP2224241B1 (ja)
JP (1) JP5264421B2 (ja)
WO (1) WO2009066469A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009145326A (ja) * 2007-11-22 2009-07-02 Fujifilm Corp 被験物測定用担体およびその製造方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5371690B2 (ja) 2008-10-24 2013-12-18 富士フイルム株式会社 断片化抗体固定化担体及びその製造方法
DE102014203266B4 (de) * 2014-02-24 2018-07-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit FRET-Paar in definierter Geometrie
JP6525199B2 (ja) * 2014-11-26 2019-06-05 国立大学法人広島大学 インスリンの検出方法、および、インスリンの検出キット
CN110018142B (zh) * 2019-03-20 2021-10-22 西南交通大学 复合荧光基底、复合荧光基底的制备方法以及应用
TW202337974A (zh) * 2021-08-27 2023-10-01 國立大學法人神戶大學 用於於基材上產率良好地形成空孔之技術之核殼模板分子、粒子

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JP2002311031A (ja) * 2001-04-18 2002-10-23 Sekisui Chem Co Ltd 分子認識蛍光体、それを用いた標的物質の測定方法
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JP2006090781A (ja) 2004-09-22 2006-04-06 Fuji Photo Film Co Ltd バイオセンサー
JP2006138656A (ja) 2004-11-10 2006-06-01 Kyowa Medex Co Ltd 分子インプリントゲル、その製造方法、該分子インプリントゲルを用いる検体中の対象分子の測定方法および対象分子測定用試薬
JP2007040834A (ja) 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬
JP2007519525A (ja) 2003-12-09 2007-07-19 マーケム コーポレーション 材料にマークされるイメージの領域のレーザによる塗り潰し
JP2007523754A (ja) 2003-04-30 2007-08-23 バイエル・テクノロジー・サービシーズ・ゲーエムベーハー （ｆ）ｒｅｔアッセイに適したコア／シェル・ナノ粒子

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US6689574B1 (en) * 1997-10-07 2004-02-10 Merck & Co., Inc. Assays for nuclear receptor agonists and antagonists using fluorescence resonance energy transfer
CA2305711A1 (en) 1997-10-07 1999-04-15 Merck & Co., Inc. Assays for nuclear receptor ligands using fret
JP2003075443A (ja) * 2001-09-03 2003-03-12 Sekisui Chem Co Ltd 標的物質測定試薬、それを用いた標的物質の測定方法
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JP2007518107A (ja) * 2004-01-13 2007-07-05 ユー．エス． ジェノミクス， インコーポレイテッド ポリマーを使用する溶液中の分析物の検出および定量化
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JP2002311031A (ja) * 2001-04-18 2002-10-23 Sekisui Chem Co Ltd 分子認識蛍光体、それを用いた標的物質の測定方法
JP2007523754A (ja) 2003-04-30 2007-08-23 バイエル・テクノロジー・サービシーズ・ゲーエムベーハー （ｆ）ｒｅｔアッセイに適したコア／シェル・ナノ粒子
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See also references of EP2224241A4
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009145326A (ja) * 2007-11-22 2009-07-02 Fujifilm Corp 被験物測定用担体およびその製造方法

Also Published As

Publication number Publication date
US8236575B2 (en) 2012-08-07
US20100290954A1 (en) 2010-11-18
JP2009145326A (ja) 2009-07-02
EP2224241A1 (en) 2010-09-01
JP5264421B2 (ja) 2013-08-14
EP2224241B1 (en) 2014-04-09
EP2224241A4 (en) 2011-04-20

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