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WO2009066181A3 - Pastilles de chlorhydrate de duloxétine pour administration orale à libération retardée - Google Patents

Pastilles de chlorhydrate de duloxétine pour administration orale à libération retardée Download PDF

Info

Publication number
WO2009066181A3
WO2009066181A3 PCT/IB2008/003741 IB2008003741W WO2009066181A3 WO 2009066181 A3 WO2009066181 A3 WO 2009066181A3 IB 2008003741 W IB2008003741 W IB 2008003741W WO 2009066181 A3 WO2009066181 A3 WO 2009066181A3
Authority
WO
WIPO (PCT)
Prior art keywords
duloxentine
release
oral delayed
hydrochloride pellets
pellets
Prior art date
Application number
PCT/IB2008/003741
Other languages
English (en)
Other versions
WO2009066181A2 (fr
Inventor
Perez Sergio Lloret
Pena Agnes Fernandez
Original Assignee
Combino Pharm Sl
Perez Sergio Lloret
Pena Agnes Fernandez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combino Pharm Sl, Perez Sergio Lloret, Pena Agnes Fernandez filed Critical Combino Pharm Sl
Publication of WO2009066181A2 publication Critical patent/WO2009066181A2/fr
Publication of WO2009066181A3 publication Critical patent/WO2009066181A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des pastilles de chlorhydrate de duloxétine pour administration orale à libération retardée. L'invention concerne en outre des procédés permettant leur préparation et leur utilisation.
PCT/IB2008/003741 2007-07-09 2008-07-09 Pastilles de chlorhydrate de duloxétine pour administration orale à libération retardée WO2009066181A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92969707P 2007-07-09 2007-07-09
US60/929,697 2007-07-09

Publications (2)

Publication Number Publication Date
WO2009066181A2 WO2009066181A2 (fr) 2009-05-28
WO2009066181A3 true WO2009066181A3 (fr) 2009-08-20

Family

ID=40667910

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/003741 WO2009066181A2 (fr) 2007-07-09 2008-07-09 Pastilles de chlorhydrate de duloxétine pour administration orale à libération retardée

Country Status (2)

Country Link
AR (1) AR067502A1 (fr)
WO (1) WO2009066181A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010037849A1 (fr) * 2008-10-02 2010-04-08 Laboratorios Del Dr. Esteve, S.A. Pastilles de duloxétine gastro-résistantes
WO2011039768A2 (fr) * 2009-09-17 2011-04-07 Cadila Healthcare Limited Compositions pharmaceutiques pour réduire une libération massive induite par l'alcool
PL224543B1 (pl) 2013-08-21 2017-01-31 Pabianickie Zakłady Farm Polfa Spółka Akcyjna Dojelitowa tabletka duloksetyny

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0693282A2 (fr) * 1994-07-18 1996-01-24 Eli Lilly And Company Pilules entériques contenant de la duloxétine
WO1997033880A1 (fr) * 1996-03-11 1997-09-18 Eli Lilly And Company Methodes de traitement ou de prevention de la cystite interstitielle
EP1640000A2 (fr) * 2002-11-27 2006-03-29 Boehringer Ingelheim International GmbH Composition pharmaceutique comprenant un agoniste de l'adrénocepteur béta-3 et un inhibiteur de la recapture de la sérotonine et/ou de la norépinéphrine
WO2007034503A2 (fr) * 2005-06-20 2007-03-29 Cadila Healthcare Limited Formulation galenique a liberation commandee de duloxetine
WO2007139886A2 (fr) * 2006-05-22 2007-12-06 Teva Pharmaceutical Industries Ltd. Formulations à libération retardée de chlorhydrate de duloxétine
EP1938840A1 (fr) * 2006-12-27 2008-07-02 LEK Pharmaceuticals D.D. Composition à base de Duletoxine
WO2008129501A2 (fr) * 2007-04-20 2008-10-30 Wockhardt Research Centre Compositions pharmaceutiques de duloxetine

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0693282A2 (fr) * 1994-07-18 1996-01-24 Eli Lilly And Company Pilules entériques contenant de la duloxétine
WO1997033880A1 (fr) * 1996-03-11 1997-09-18 Eli Lilly And Company Methodes de traitement ou de prevention de la cystite interstitielle
EP1640000A2 (fr) * 2002-11-27 2006-03-29 Boehringer Ingelheim International GmbH Composition pharmaceutique comprenant un agoniste de l'adrénocepteur béta-3 et un inhibiteur de la recapture de la sérotonine et/ou de la norépinéphrine
WO2007034503A2 (fr) * 2005-06-20 2007-03-29 Cadila Healthcare Limited Formulation galenique a liberation commandee de duloxetine
WO2007139886A2 (fr) * 2006-05-22 2007-12-06 Teva Pharmaceutical Industries Ltd. Formulations à libération retardée de chlorhydrate de duloxétine
EP1938840A1 (fr) * 2006-12-27 2008-07-02 LEK Pharmaceuticals D.D. Composition à base de Duletoxine
WO2008129501A2 (fr) * 2007-04-20 2008-10-30 Wockhardt Research Centre Compositions pharmaceutiques de duloxetine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JANSEN P J ET AL: "CHARACTERIZATION OF IMPURITIES FORMED BY INTERACTION OF DULOXETINE HCI WITH ENTERIC POLYMERS HYDROXYPROPYL METHYLCELLULOSE ACETATE SUCCINATE AND HYDROXYPROPYL METHYLCELLULOSE PHTHALATE", JOURNAL OF PHARMACEUTICAL SCIENCE, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, vol. 87, no. 1, 1 January 1998 (1998-01-01), pages 81 - 85, XP000891949, ISSN: 0022-3549 *

Also Published As

Publication number Publication date
WO2009066181A2 (fr) 2009-05-28
AR067502A1 (es) 2009-10-14

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