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WO2009060621A1 - 術後の癒着を抑制するための医療用組成物 - Google Patents

術後の癒着を抑制するための医療用組成物 Download PDF

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Publication number
WO2009060621A1
WO2009060621A1 PCT/JP2008/003228 JP2008003228W WO2009060621A1 WO 2009060621 A1 WO2009060621 A1 WO 2009060621A1 JP 2008003228 W JP2008003228 W JP 2008003228W WO 2009060621 A1 WO2009060621 A1 WO 2009060621A1
Authority
WO
WIPO (PCT)
Prior art keywords
medical composition
surgical adhesion
preventing post
adhesion
post
Prior art date
Application number
PCT/JP2008/003228
Other languages
English (en)
French (fr)
Inventor
Shouji Ooya
Tetsuo Hiratou
Kentaro Nakamura
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Publication of WO2009060621A1 publication Critical patent/WO2009060621A1/ja

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/043Proteins; Polypeptides; Degradation products thereof
    • A61L31/047Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

 本発明の目的は、薬剤貯蔵、徐放用担体としての機能を保持しつつ、特に心筋組織での繊維組織形成を抑制し、かつ、周辺組織との癒着を抑制することができる医療用組成物を提供することである。本発明によれば、架橋されたアルブミンを含有する、術後の癒着を抑制するための医療用組成物が提供される。  
PCT/JP2008/003228 2007-11-08 2008-11-07 術後の癒着を抑制するための医療用組成物 WO2009060621A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-290552 2007-11-08
JP2007290552 2007-11-08

Publications (1)

Publication Number Publication Date
WO2009060621A1 true WO2009060621A1 (ja) 2009-05-14

Family

ID=40625528

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003228 WO2009060621A1 (ja) 2007-11-08 2008-11-07 術後の癒着を抑制するための医療用組成物

Country Status (1)

Country Link
WO (1) WO2009060621A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362856A (zh) * 2011-11-02 2012-02-29 珠海亿胜生物制药有限公司 重组牛碱性成纤维细胞生长因子外用溶液

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002020310A (ja) * 2000-06-30 2002-01-23 Nipro Corp 組織癒着防止剤
WO2006016600A1 (ja) * 2004-08-10 2006-02-16 National Institute For Materials Science 酒石酸誘導体及び該誘導体により合成された高分子架橋体
WO2006085653A1 (ja) * 2005-02-14 2006-08-17 Medgel Corporation 医療用ハイドロゲル
WO2006136870A1 (fr) * 2005-06-21 2006-12-28 Antoine Turzi Hydrogel bioresorbable

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002020310A (ja) * 2000-06-30 2002-01-23 Nipro Corp 組織癒着防止剤
WO2006016600A1 (ja) * 2004-08-10 2006-02-16 National Institute For Materials Science 酒石酸誘導体及び該誘導体により合成された高分子架橋体
WO2006085653A1 (ja) * 2005-02-14 2006-08-17 Medgel Corporation 医療用ハイドロゲル
WO2006136870A1 (fr) * 2005-06-21 2006-12-28 Antoine Turzi Hydrogel bioresorbable

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"The Society of Polymer Science, Japan Preprints of Research Group on Biochemical Polymer Symposium, 23 July, 2007 (23.07.07)", vol. 36TH, article YASUMUNE YAMAZOE: "Kessei Albumin o Mochiita Saibo Setchaku Seigyo", pages: 1 - 2 *
MOTOYUKI SUZUKI ET AL.: "Setchaku Izonsei Dobutsu Saibo no Fuchaku ni Oyobosu Kessei Tanpaku no Eikyo", MONTHLY JOURNAL OF INSTITUTE OF INDUSTRIAL SCIENCE, vol. 41, no. 3, March 1989 (1989-03-01), pages 175 - 178 *
YASUMUNE YAMAZOE ET AL.: "Kessei Albumin Film no Sakusei to Sono Bussei ni Kansuru Kenkyu", POLYMER PREPRINTS, JAPAN, vol. 50, no. 5, 7 May 2001 (2001-05-07), pages 1012 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362856A (zh) * 2011-11-02 2012-02-29 珠海亿胜生物制药有限公司 重组牛碱性成纤维细胞生长因子外用溶液

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