WO2009053993A3 - Process for preparation of novel salt of voriconazole oxalate form-c - Google Patents
Process for preparation of novel salt of voriconazole oxalate form-c Download PDFInfo
- Publication number
- WO2009053993A3 WO2009053993A3 PCT/IN2007/000562 IN2007000562W WO2009053993A3 WO 2009053993 A3 WO2009053993 A3 WO 2009053993A3 IN 2007000562 W IN2007000562 W IN 2007000562W WO 2009053993 A3 WO2009053993 A3 WO 2009053993A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- voriconazole
- preparation
- novel salt
- oxalate form
- oxalate
- Prior art date
Links
- 229960004740 voriconazole Drugs 0.000 title abstract 2
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical group OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- BCEHBSKCWLPMDN-MGPLVRAMSA-N voriconazole Chemical compound C1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=NC=C1F BCEHBSKCWLPMDN-MGPLVRAMSA-N 0.000 title 1
- -1 Voriconazole oxalate salt Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The subject matter of the present application is a novel polymorphic Voriconazole oxalate salt of form C and a process for preparing thereof.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2382CH2007 | 2007-10-22 | ||
IN2382/CHE/2007 | 2007-10-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009053993A2 WO2009053993A2 (en) | 2009-04-30 |
WO2009053993A3 true WO2009053993A3 (en) | 2009-09-24 |
Family
ID=40580200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2007/000562 WO2009053993A2 (en) | 2007-10-22 | 2007-12-03 | Process for preparation of novel salt of voriconazole oxalate form-c |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009053993A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2788344A4 (en) * | 2011-12-06 | 2015-06-24 | Basf Se | Multicomponent crystalline system of voriconazole with fumaric acid |
EP3581566A3 (en) * | 2016-11-28 | 2020-01-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of fungal infections |
CN108276387B (en) * | 2018-01-24 | 2020-12-18 | 成都倍特药业股份有限公司 | Purification method of voriconazole |
IL298010A (en) * | 2020-05-12 | 2023-01-01 | Cellix Bio Private Ltd | Process for the preparation salts of triazole compounds |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005084671A2 (en) * | 2004-02-04 | 2005-09-15 | Pfizer Limited | Combination of voriconazole and an antifungal cyp2c19 inhibitor |
WO2006065726A2 (en) * | 2004-12-14 | 2006-06-22 | Dr. Reddy's Laboratories Ltd. | Process for preparing voriconazole |
CN1847243A (en) * | 2005-07-08 | 2006-10-18 | 北京博尔达生物技术开发有限公司 | Prepn process and prepn of new soluble voriconazole salt |
WO2007013096A1 (en) * | 2005-06-30 | 2007-02-01 | Msn Laboratories Limited | Improved process for the preparation of 2r, 3s-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl) butan-2-ol (voriconazole) |
-
2007
- 2007-12-03 WO PCT/IN2007/000562 patent/WO2009053993A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005084671A2 (en) * | 2004-02-04 | 2005-09-15 | Pfizer Limited | Combination of voriconazole and an antifungal cyp2c19 inhibitor |
WO2006065726A2 (en) * | 2004-12-14 | 2006-06-22 | Dr. Reddy's Laboratories Ltd. | Process for preparing voriconazole |
WO2007013096A1 (en) * | 2005-06-30 | 2007-02-01 | Msn Laboratories Limited | Improved process for the preparation of 2r, 3s-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl) butan-2-ol (voriconazole) |
CN1847243A (en) * | 2005-07-08 | 2006-10-18 | 北京博尔达生物技术开发有限公司 | Prepn process and prepn of new soluble voriconazole salt |
Also Published As
Publication number | Publication date |
---|---|
WO2009053993A2 (en) | 2009-04-30 |
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