WO2009053750A3 - Novel crystalline and amorphous forms - Google Patents
Novel crystalline and amorphous forms Download PDFInfo
- Publication number
- WO2009053750A3 WO2009053750A3 PCT/GB2008/050988 GB2008050988W WO2009053750A3 WO 2009053750 A3 WO2009053750 A3 WO 2009053750A3 GB 2008050988 W GB2008050988 W GB 2008050988W WO 2009053750 A3 WO2009053750 A3 WO 2009053750A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amorphous forms
- novel crystalline
- novel
- forms
- relates
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003892 tartrate salts Chemical class 0.000 abstract 1
- IKBKZGMPCYNSLU-RGVLZGJSSA-N tegaserod Chemical compound C1=C(OC)C=C2C(/C=N/NC(=N)NCCCCC)=CNC2=C1 IKBKZGMPCYNSLU-RGVLZGJSSA-N 0.000 abstract 1
- 229960002876 tegaserod Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to novel amorphous and crystalline forms of the tartrate salt of tegaserod, and to processes for the preparation of these novel forms. The invention also relates to pharmaceutical compositions containing these novel forms, and to uses of said compositions to provide methods of treatingpatients suffering from gastrointestinal disorders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2106/MUM/2007 | 2007-10-24 | ||
IN2106MU2007 | 2007-10-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009053750A2 WO2009053750A2 (en) | 2009-04-30 |
WO2009053750A3 true WO2009053750A3 (en) | 2009-08-06 |
Family
ID=40289166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2008/050988 WO2009053750A2 (en) | 2007-10-24 | 2008-10-24 | Novel crystalline and amorphous forms |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009053750A2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006116953A1 (en) * | 2005-05-02 | 2006-11-09 | Zentiva, A.S. | A method for the preparation of tegaserod and slected salts thereof |
WO2008149154A2 (en) * | 2007-06-05 | 2008-12-11 | Generics [Uk] Limited | Tegaserod succinate and polymorphic forms |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3885357T2 (en) | 1987-06-29 | 1994-03-24 | Duphar Int Res | Fused indole derivatives. |
HUT64023A (en) | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
GB9721139D0 (en) | 1997-10-07 | 1997-12-03 | Glaxo Group Ltd | Medicaments |
-
2008
- 2008-10-24 WO PCT/GB2008/050988 patent/WO2009053750A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006116953A1 (en) * | 2005-05-02 | 2006-11-09 | Zentiva, A.S. | A method for the preparation of tegaserod and slected salts thereof |
WO2008149154A2 (en) * | 2007-06-05 | 2008-12-11 | Generics [Uk] Limited | Tegaserod succinate and polymorphic forms |
Also Published As
Publication number | Publication date |
---|---|
WO2009053750A2 (en) | 2009-04-30 |
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