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WO2009053742A3 - Salts of nefopam and their use in therapy - Google Patents

Salts of nefopam and their use in therapy Download PDF

Info

Publication number
WO2009053742A3
WO2009053742A3 PCT/GB2008/050979 GB2008050979W WO2009053742A3 WO 2009053742 A3 WO2009053742 A3 WO 2009053742A3 GB 2008050979 W GB2008050979 W GB 2008050979W WO 2009053742 A3 WO2009053742 A3 WO 2009053742A3
Authority
WO
WIPO (PCT)
Prior art keywords
nefopam
therapy
salts
relates
novel salts
Prior art date
Application number
PCT/GB2008/050979
Other languages
French (fr)
Other versions
WO2009053742A2 (en
Inventor
Peter Tiffin
Original Assignee
Sosei R & D Ltd
Peter Tiffin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sosei R & D Ltd, Peter Tiffin filed Critical Sosei R & D Ltd
Publication of WO2009053742A2 publication Critical patent/WO2009053742A2/en
Publication of WO2009053742A3 publication Critical patent/WO2009053742A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22Eight-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

This invention relates to novel salts of Nefopam, which may be suitable for use in therapy.
PCT/GB2008/050979 2007-10-25 2008-10-23 Salts of nefopam and their use in therapy WO2009053742A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0721013.1A GB0721013D0 (en) 2007-10-25 2007-10-25 New Salts
GB0721013.1 2007-10-25

Publications (2)

Publication Number Publication Date
WO2009053742A2 WO2009053742A2 (en) 2009-04-30
WO2009053742A3 true WO2009053742A3 (en) 2009-07-23

Family

ID=38829977

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2008/050979 WO2009053742A2 (en) 2007-10-25 2008-10-23 Salts of nefopam and their use in therapy

Country Status (2)

Country Link
GB (1) GB0721013D0 (en)
WO (1) WO2009053742A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2940911B1 (en) * 2009-01-13 2012-09-21 Philippe Perovitch FORMULATION FOR ORAL TRANSMUCOSAL ADMINISTRATION OF ANTALGIC AND / OR ANTI-SPASMODIC MOLECULES
CA2782472C (en) 2009-12-15 2019-04-16 The Hospital For Sick Children Method of treating scars and beta-catenin-mediated disorders
US10736905B1 (en) 2016-09-09 2020-08-11 Shahin Fatholahi Nefopam dosage forms and methods of treatment
US10736874B1 (en) 2017-09-08 2020-08-11 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
US11446311B2 (en) 2017-09-08 2022-09-20 Shahin Fatholahi Methods for treating pain associated with sickle cell disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105833A1 (en) * 2002-06-17 2003-12-24 Arakis Ltd. Formulation of nefopam and its use in the treatment of pain
WO2005056539A2 (en) * 2003-12-12 2005-06-23 Arakis Ltd. A process for the resolution of nefopam

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105833A1 (en) * 2002-06-17 2003-12-24 Arakis Ltd. Formulation of nefopam and its use in the treatment of pain
WO2005056539A2 (en) * 2003-12-12 2005-06-23 Arakis Ltd. A process for the resolution of nefopam

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOLT, A. G. ET AL: "Stereoselective demethylation of the enantiomers of nefopam, an experimental antidepressant and skeletal muscle relaxant", XENOBIOTICA , 4(6), 355-63 CODEN: XENOBH; ISSN: 0049-8254, 1974, XP002525368 *

Also Published As

Publication number Publication date
WO2009053742A2 (en) 2009-04-30
GB0721013D0 (en) 2007-12-05

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