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WO2009053628A3 - Nouveaux composes, préparation et utilisations - Google Patents

Nouveaux composes, préparation et utilisations Download PDF

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Publication number
WO2009053628A3
WO2009053628A3 PCT/FR2008/051838 FR2008051838W WO2009053628A3 WO 2009053628 A3 WO2009053628 A3 WO 2009053628A3 FR 2008051838 W FR2008051838 W FR 2008051838W WO 2009053628 A3 WO2009053628 A3 WO 2009053628A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel compounds
preparation
relates
present
compounds
Prior art date
Application number
PCT/FR2008/051838
Other languages
English (en)
Other versions
WO2009053628A2 (fr
Inventor
Gaetan Lucien Alfred Mislin
Isabelle Jeanne Louise Schalk
Gerard Jean Marie Lescoat
Francois Remi Gaboriau
David Rodriguez-Lucena
Original Assignee
Univ Pasteur
Inst Nat Sante Rech Med
Centre Nat Rech Scient
Gaetan Lucien Alfred Mislin
Isabelle Jeanne Louise Schalk
Gerard Jean Marie Lescoat
Francois Remi Gaboriau
David Rodriguez-Lucena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pasteur, Inst Nat Sante Rech Med, Centre Nat Rech Scient, Gaetan Lucien Alfred Mislin, Isabelle Jeanne Louise Schalk, Gerard Jean Marie Lescoat, Francois Remi Gaboriau, David Rodriguez-Lucena filed Critical Univ Pasteur
Publication of WO2009053628A2 publication Critical patent/WO2009053628A2/fr
Publication of WO2009053628A3 publication Critical patent/WO2009053628A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouveaux composés, les compositions pharmaceutiques les comprenant ainsi que leurs applications thérapeutiques dans les domaines de la santé humaine et animale. La présente invention a également trait à un procédé de préparation de ces composés.
PCT/FR2008/051838 2007-10-11 2008-10-10 Nouveaux composes, préparation et utilisations WO2009053628A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0758229A FR2922210A1 (fr) 2007-10-11 2007-10-11 Nouveaux composes, preparation et utilisations
FR0758229 2007-10-11

Publications (2)

Publication Number Publication Date
WO2009053628A2 WO2009053628A2 (fr) 2009-04-30
WO2009053628A3 true WO2009053628A3 (fr) 2009-06-18

Family

ID=39281755

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/051838 WO2009053628A2 (fr) 2007-10-11 2008-10-10 Nouveaux composes, préparation et utilisations

Country Status (2)

Country Link
FR (1) FR2922210A1 (fr)
WO (1) WO2009053628A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2603385C (fr) 2005-04-04 2014-07-15 University Of Florida Research Foundation, Inc. Analogues de polyether desferrithiocine et leurs utilisations dans le traitement de conditions telles que la surcharge metallique, la fatigue oxydative et les conditions neoplasiques et pre-neoplasiques
WO2008115433A1 (fr) 2007-03-15 2008-09-25 University Of Florida Analogues de polyéther de desferrithiocine
GB0918722D0 (en) * 2009-10-26 2009-12-09 Univ Birmingham Anti cancer agent
MX368275B (es) 2011-12-16 2019-09-26 Univ Florida Usos de análogos de 4'-desferritiocina.
CA2930966A1 (fr) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Analogues de la desferrithiocine et leurs utilisations
WO2015077652A1 (fr) * 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Analogues de la désazadesferrithiocine et leurs utilisations
CN107708693A (zh) 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005034949A1 (fr) * 2003-09-09 2005-04-21 University Of Florida Derives de desferrithiocine et leur utilisation en tant que chelateurs du fer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ509172A (en) * 1998-09-21 2004-02-27 Univ Florida Antimalarial agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005034949A1 (fr) * 2003-09-09 2005-04-21 University Of Florida Derives de desferrithiocine et leur utilisation en tant que chelateurs du fer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HOVEYDA H R ET AL: "DESIGN AND SYNTHESIS OF MULTIDENTATE 2-(2'-HYDROXYPHENYL)-2-THIAZOLI NES FOR BIOMEDICAL APPLICATION", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 48, no. 25, 1992, pages 5219 - 5226, XP001160881, ISSN: 0040-4020 *

Also Published As

Publication number Publication date
FR2922210A1 (fr) 2009-04-17
WO2009053628A2 (fr) 2009-04-30

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