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WO2009052810A3 - Matrices de fibrilles de collagène - Google Patents

Matrices de fibrilles de collagène Download PDF

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Publication number
WO2009052810A3
WO2009052810A3 PCT/DE2008/001745 DE2008001745W WO2009052810A3 WO 2009052810 A3 WO2009052810 A3 WO 2009052810A3 DE 2008001745 W DE2008001745 W DE 2008001745W WO 2009052810 A3 WO2009052810 A3 WO 2009052810A3
Authority
WO
WIPO (PCT)
Prior art keywords
collagen fibril
fibril matrices
morphology
matrices
substrate materials
Prior art date
Application number
PCT/DE2008/001745
Other languages
German (de)
English (en)
Other versions
WO2009052810A2 (fr
Inventor
Babette Lanfer
Uwe Freudenberg
Ralf Zimmermann
Carsten Werner
Original Assignee
Leibniz-Institut Für Polymerforschung Dresden E.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leibniz-Institut Für Polymerforschung Dresden E.V. filed Critical Leibniz-Institut Für Polymerforschung Dresden E.V.
Publication of WO2009052810A2 publication Critical patent/WO2009052810A2/fr
Publication of WO2009052810A3 publication Critical patent/WO2009052810A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne des matrices de fibrilles de collagène qui peuvent être obtenues par un procédé de revêtement de supports avec des matrices de fibrilles de collagène de structure et de morphologie définies, à partir de solutions qui s'écoulent. La commande de la structure et de la morphologie s'effectue ici en faisant varier un ou plusieurs paramètres différents, sachant que le groupe des paramètres à faire varier comprend : - les matériaux de substrats; - les revêtements tensioactifs sur les matériaux de substrats; - la concentration de la solution; - le temps de fibrillation; et - les conditions marginales de dynamique des fluides du processus de séparation.
PCT/DE2008/001745 2007-10-24 2008-10-22 Matrices de fibrilles de collagène WO2009052810A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007000564.6 2007-10-24
DE102007000564.6A DE102007000564B4 (de) 2007-10-24 2007-10-24 Verfahren zur Beschichtung von Trägern mit Kollagenfibrillenmatrices

Publications (2)

Publication Number Publication Date
WO2009052810A2 WO2009052810A2 (fr) 2009-04-30
WO2009052810A3 true WO2009052810A3 (fr) 2009-10-15

Family

ID=40467077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2008/001745 WO2009052810A2 (fr) 2007-10-24 2008-10-22 Matrices de fibrilles de collagène

Country Status (2)

Country Link
DE (1) DE102007000564B4 (fr)
WO (1) WO2009052810A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004050134A2 (fr) * 2001-11-30 2004-06-17 Cambridge Polymer Group Structures polymeres alignees en couches et leurs procedes de fabrication
US20060019361A1 (en) * 2004-07-26 2006-01-26 Agency For Science, Technology And Research Immobilization of cells in a matrix formed by biocompatible charged polymers under laminar flow conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE327038T1 (de) * 2001-05-30 2006-06-15 Biolex Inc Testplatte für hochdurchsatzscreening

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004050134A2 (fr) * 2001-11-30 2004-06-17 Cambridge Polymer Group Structures polymeres alignees en couches et leurs procedes de fabrication
US20060019361A1 (en) * 2004-07-26 2006-01-26 Agency For Science, Technology And Research Immobilization of cells in a matrix formed by biocompatible charged polymers under laminar flow conditions

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
ELSDALE T ET AL: "COLLAGEN SUBSTRATA FOR STUDIES OF CELL BEHAVIOR", JOURNAL OF CELL BIOLOGY, vol. 54, no. 3, 1972, pages 626 - 637, XP002522579, ISSN: 0021-9525 *
GUO ET AL: "Flow and magnetic field induced collagen alignment", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 28, no. 6, 28 November 2006 (2006-11-28), pages 1105 - 1114, XP005788944, ISSN: 0142-9612 *
JIANG FENGZHI ET AL: "Creating nanoscopic collagen matrices using atomic force microscopy.", MICROSCOPY RESEARCH AND TECHNIQUE AUG 2004, vol. 64, no. 5-6, August 2004 (2004-08-01), pages 435 - 440, XP002522580, ISSN: 1059-910X *
KÖSTER SARAH ET AL: "An in situ study of collagen self-assembly processes.", BIOMACROMOLECULES JAN 2008, vol. 9, no. 1, January 2008 (2008-01-01), pages 199 - 207, XP002522578, ISSN: 1526-4602 *
LANFER B ET AL: "Aligned fibrillar collagen matrices obtained by shear flow deposition", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 29, no. 28, 1 October 2008 (2008-10-01), pages 3888 - 3895, XP023316152, ISSN: 0142-9612, [retrieved on 20080707] *
PHILIP LEE ET AL: "Microfluidic alignment of collagen fibers for in vitro cell culture", BIOMEDICAL MICRODEVICES, KLUWER ACADEMIC PUBLISHERS, BO, vol. 8, no. 1, 1 March 2006 (2006-03-01), pages 35 - 41, XP019205127, ISSN: 1572-8781 *
POOLE K ET AL: "Molecular-scale Topographic Cues Induce the Orientation and Directional Movement of Fibroblasts on Two-dimensional Collagen Surfaces", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 349, no. 2, 3 June 2005 (2005-06-03), pages 380 - 386, XP004879719, ISSN: 0022-2836 *
RUBERTI J W ET AL: "NANOSCALE ENGINEERING OF TYPE I COLLAGEN FIBRILS TO MIMIC THE MULTIPLE LAYERS OF ALIGNED LAMELLAE IN CORNEA", ANNUAL MEETING OF THE ASSOCIATION FOR RESEARCH IN VISION ANDOPHTHALMOLOGY, XX, XX, vol. 44, 1 January 2003 (2003-01-01), pages AbstractNo.4218, XP001180573 *
THAKAR R G ET AL: "Regulation of vascular smooth muscle cells by micropatterning", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 307, no. 4, 8 August 2003 (2003-08-08), pages 883 - 890, XP004439219, ISSN: 0006-291X *
TORBET ET AL: "Orthogonal scaffold of magnetically aligned collagen lamellae for corneal stroma reconstruction", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 28, no. 29, 10 August 2007 (2007-08-10), pages 4268 - 4276, XP022192635, ISSN: 0142-9612 *

Also Published As

Publication number Publication date
DE102007000564A1 (de) 2009-04-30
DE102007000564B4 (de) 2016-11-17
WO2009052810A2 (fr) 2009-04-30

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