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WO2008139786A1 - 微細針ディバイス及びその製造方法 - Google Patents

微細針ディバイス及びその製造方法 Download PDF

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Publication number
WO2008139786A1
WO2008139786A1 PCT/JP2008/056471 JP2008056471W WO2008139786A1 WO 2008139786 A1 WO2008139786 A1 WO 2008139786A1 JP 2008056471 W JP2008056471 W JP 2008056471W WO 2008139786 A1 WO2008139786 A1 WO 2008139786A1
Authority
WO
WIPO (PCT)
Prior art keywords
microneedle device
microneedles
skin surface
producing
same
Prior art date
Application number
PCT/JP2008/056471
Other languages
English (en)
French (fr)
Inventor
Ying-Shu Quan
Fumio Kamiyama
Yoshikazu Tobinaga
Tomoya Kitagawa
Kentaro Ohshima
Akira Yamamoto
Original Assignee
Cosmed Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosmed Pharmaceutical Co., Ltd. filed Critical Cosmed Pharmaceutical Co., Ltd.
Priority to KR1020097023674A priority Critical patent/KR101400545B1/ko
Priority to US12/599,860 priority patent/US8167852B2/en
Priority to CN2008800150482A priority patent/CN101687090B/zh
Publication of WO2008139786A1 publication Critical patent/WO2008139786A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/04—Processes
    • Y10T83/0448—With subsequent handling [i.e., of product]
    • Y10T83/0467—By separating products from each other

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)

Abstract

　皮膚表面内に容易に刺入でき、皮膚表面内において溶解又は膨潤する微細針を有する微細針ディバイスを提供する。 　微細針ディバイスは、基盤と、基盤上に配置された円錐状または多角錐状の皮膚表面内挿入用微細針とを備えている。皮膚表面内挿入用微細針は、キトサン、コラーゲン、ゼラチン及びヒアルロン酸よりなる群から選ばれた１種または複数種類の生体由来物質を５０重量％以上含有し、生体内で溶解又は膨潤しうる素材からなる。  
PCT/JP2008/056471 2007-05-15 2008-04-01 微細針ディバイス及びその製造方法 WO2008139786A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020097023674A KR101400545B1 (ko) 2007-05-15 2008-04-01 마이크로니들 디바이스 및 그의 제조 방법
US12/599,860 US8167852B2 (en) 2007-05-15 2008-04-01 Microneedle device and method for producing the same
CN2008800150482A CN101687090B (zh) 2007-05-15 2008-04-01 一种微针系统及其制造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-155752 2007-05-15
JP2007155752A JP2008284318A (ja) 2007-05-15 2007-05-15 生体由来物質からなる投薬用微細針

Publications (1)

Publication Number Publication Date
WO2008139786A1 true WO2008139786A1 (ja) 2008-11-20

Family

ID=40002009

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/056471 WO2008139786A1 (ja) 2007-05-15 2008-04-01 微細針ディバイス及びその製造方法

Country Status (5)

Country Link
US (1) US8167852B2 (ja)
JP (1) JP2008284318A (ja)
KR (1) KR101400545B1 (ja)
CN (1) CN101687090B (ja)
WO (1) WO2008139786A1 (ja)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011002034A1 (ja) * 2009-07-01 2011-01-06 凸版印刷株式会社 針状体
CN109069812A (zh) * 2016-04-07 2018-12-21 实验室和人们 利用生物可吸收金属的微针
WO2020004428A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020004666A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020017441A1 (en) 2018-07-17 2020-01-23 L'oreal Microneedle sheet
US10603477B2 (en) 2014-03-28 2020-03-31 Allergan, Inc. Dissolvable microneedles for skin treatment
WO2020130157A1 (en) 2018-12-21 2020-06-25 L'oreal Kit and cosmetic process using microneedle sheet
EP3695876A1 (en) 2019-02-18 2020-08-19 L'oreal Pencil for inserting micro-implants inside upper skin layers
EP3698841A1 (en) 2019-02-19 2020-08-26 L'oreal Injection device
WO2020200407A1 (en) 2019-03-29 2020-10-08 L'oreal Frozen micro-implants and method of making same
US11065428B2 (en) 2017-02-17 2021-07-20 Allergan, Inc. Microneedle array with active ingredient

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2820335T3 (es) 2007-04-16 2021-04-20 Corium Inc Matrices de microagujas coladas con disolvente que contienen agente activo
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP2010141278A (ja) * 2008-12-10 2010-06-24 Yoshiichi Tobinaga 多糖質配線基板及びその製造方法
JP5499509B2 (ja) * 2009-04-02 2014-05-21 凸版印刷株式会社 針状物体の製造方法
CA2759850C (en) * 2009-04-24 2019-10-22 Corium International, Inc. Methods for manufacturing microprojection arrays
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
WO2011071287A2 (ko) 2009-12-07 2011-06-16 에스케이케미칼 주식회사 활성 성분의 흡수 속도가 개선된 마이크로니들
CA2798145C (en) 2010-05-04 2022-10-18 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CN102917752A (zh) * 2010-05-28 2013-02-06 久光制药株式会社 带微小突起的阵列
CN102917751A (zh) * 2010-05-28 2013-02-06 久光制药株式会社 具有带有微小突起的阵列的装置
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
JP5672554B2 (ja) * 2010-08-19 2015-02-18 Ｊｃｒファーマ株式会社 皮下又は経皮吸収用組成物
JP5687170B2 (ja) 2011-03-30 2015-03-18 コスメディ製薬株式会社 マイクロニードルパッチ収納容器
CN102178616B (zh) * 2011-05-06 2013-06-05 广州保税区雅兰国际化妆品有限公司 一种玻尿酸微针贴膜及其制备方法
KR101990654B1 (ko) 2011-09-22 2019-06-18 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 패치 수납 용기
KR101931845B1 (ko) 2011-10-20 2018-12-21 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 용착법
EP2772279B1 (en) * 2011-10-28 2019-06-05 Toppan Printing Co., Ltd. Hollow needles manufacturing method and hollow needles
US20140371713A1 (en) * 2012-02-17 2014-12-18 Cosmed Pharmaceutical Co., Ltd. Short-time soluble microneedle
CN102580232B (zh) * 2012-02-23 2013-12-18 游学秋 一种丝素微针系统和丝素纳米颗粒及其制备方法
EP2821096B1 (en) 2012-02-29 2019-05-22 Toppan Printing Co., Ltd. Method for manufacturing needle-like material
WO2013166162A1 (en) 2012-05-01 2013-11-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
JP2015522342A (ja) * 2012-06-29 2015-08-06 イーエルシー マネージメント エルエルシー １つ以上の化粧品成分を含むマイクロニードル
EP2866607A4 (en) * 2012-06-29 2016-07-13 Elc Man Llc SOLUBLE MICROARRAYS COMPRISING ONE OR MORE ENCAPSULATED COSMETIC INGREDIENTS
EP2895217B1 (en) 2012-09-13 2020-10-21 Avraham Amir Delivery devices and methods for skin augmentation
US12161831B2 (en) 2012-09-13 2024-12-10 Avraham Amir Microneedles and compositions for skin augmentation
KR101435888B1 (ko) * 2012-10-23 2014-09-01 연세대학교 산학협력단 히알루론산을 이용한 생분해성 마이크로니들 제조방법
CN104755128B (zh) * 2012-11-02 2018-05-11 考司美德制药株式会社 视黄酸微针
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム， インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
JP2016506780A (ja) 2013-01-21 2016-03-07 ブキョン ファ−ム カンパニ− リミテッド マイクロニードル及びその製造用モールドならびにその製造方法
US20200230033A1 (en) * 2013-01-21 2020-07-23 Paean Aesthetics Inc. Micro-spicule composition to control its shape and method for producing the same
KR102332671B1 (ko) 2013-03-12 2021-11-30 코리움, 인크. 미세돌기 어플리케이터
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP6700170B2 (ja) 2013-03-15 2020-05-27 コリウム， インコーポレイテッド 治療剤の送達のためのマイクロアレイおよび使用の方法
AU2014237357B2 (en) 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CN104095761A (zh) * 2013-04-08 2014-10-15 上海汇林医药科技有限公司 一种高分子聚合物微针贴剂及其应用
TWI528975B (zh) * 2013-07-12 2016-04-11 國立成功大學 微針經皮傳輸裝置及應用其之微針經皮傳輸方法
US10869832B2 (en) * 2013-07-12 2020-12-22 National Cheng Kung University Substance delivery device and substance delivery method using the same
US9694142B2 (en) 2013-09-03 2017-07-04 Visage Sculpture, PLLC Device for percutaneous delivery of therapeutic agents, and a method for its use
US10232158B2 (en) 2013-09-18 2019-03-19 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
EP3068408A4 (en) * 2013-11-14 2017-09-06 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
EP3148630B1 (en) * 2014-05-28 2022-12-07 Mdapp S.R.L. A flexible dissolvable patch and its method of fabricating
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
CN104434561A (zh) * 2014-11-10 2015-03-25 广州市博卡利生物科技有限公司 一种微针面膜
CN104644456A (zh) * 2015-01-16 2015-05-27 刘春生 透皮吸收可溶性制剂贴片、制备方法及方法中使用的工具
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
KR102493996B1 (ko) * 2015-04-29 2023-01-31 주식회사 엘지생활건강 항염 효과의 성분을 포함하는 저자극 용해성 미세바늘 패치
CN104826228B (zh) * 2015-05-25 2017-12-29 成都凤磐生物科技有限公司 用于皮肤修复与保养的生物贴
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JPWO2017018086A1 (ja) * 2015-07-29 2018-02-01 Ｎｉｓｓｈａ株式会社 マイクロニードルシート
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
KR101811513B1 (ko) 2015-11-25 2017-12-20 주식회사 파이안에스테틱스 마이크로 스피큘과 이의 제조용 몰드 및 이의 제조방법
CN105434332A (zh) * 2015-12-02 2016-03-30 江汉大学 水溶性生物大分子微针膜的制备方法
CN105411997A (zh) * 2015-12-30 2016-03-23 李媚 一种可降解微结构体及其制备方法
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
CN105797266A (zh) * 2016-03-07 2016-07-27 李媚 一种微结构体及其制备方法
KR101719319B1 (ko) * 2016-04-05 2017-03-23 주식회사 엘지생활건강 효율적인 피부 천공을 위한 마이크로니들 구조
WO2017176069A2 (ko) * 2016-04-07 2017-10-12 랩앤피플주식회사 생체흡수성 금속을 이용한 마이크로 니들
KR101878414B1 (ko) * 2016-08-12 2018-07-13 연세대학교 산학협력단 마이크로니들 패치, 이의 제조방법 및 이를 이용한 알레르기 질환 진단방법
US20180092776A1 (en) 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
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US11241563B2 (en) 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
CN106808162A (zh) * 2017-02-21 2017-06-09 中山大学 一种微针阵列电极及其制备方法
KR101776659B1 (ko) * 2017-02-27 2017-09-11 주식회사 쿼드메디슨 마이크로 니들 및 이의 제조방법
US11504512B2 (en) * 2017-05-10 2022-11-22 Chee Yen Lim Method of fabricating microneedle patches
KR102388991B1 (ko) 2017-05-22 2022-04-22 삼성전자주식회사 바이오 센서, 바이오 센서의 제조방법 및 생체신호 측정장치
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WO2019088315A1 (ko) * 2017-11-01 2019-05-09 주식회사 엘지생활건강 탈모 방지제 및 발모 치료제 전달을 위한 용해성 미세바늘 패치
US20210060321A1 (en) * 2018-01-07 2021-03-04 Avraham Amir High-load microneedles and compositions for skin augmentation
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US12121618B2 (en) 2018-05-18 2024-10-22 Postech Academy-Industry Foundation Transdermal drug delivery patch and manufacturing method thereof
KR102604754B1 (ko) 2018-05-18 2023-11-22 포항공과대학교 산학협력단 경피 투과형 약물 전달 패치의 제조 방법
CA3102959A1 (en) 2018-06-29 2020-01-02 Johnson & Johnson Consumer Inc. Three-dimensional microfluidics devices for the delivery of actives
WO2020017436A1 (ja) * 2018-07-19 2020-01-23 久光製薬株式会社 マイクロニードル・シートの製造方法、およびマイクロニードル・シート
US11517729B2 (en) * 2018-08-20 2022-12-06 University Of Washington Integrated fiber microneedle device for drug and vaccine delivery
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EP3856323A1 (en) * 2018-09-24 2021-08-04 L'oreal Device comprising microneedles for cosmetic fillers delivery
KR102039582B1 (ko) * 2018-12-12 2019-11-01 주식회사 라파스 인장 공정으로 제조하기에 적합한 마이크로니들 재료의 적합성 시험 방법 및 이를 포함하는 마이크로니들 제조 방법
KR102187439B1 (ko) * 2019-01-30 2020-12-07 주식회사 라파스 마이크로니들 패취를 이용한 최소 침습적 피부 생체 검사 방법
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
EP3854375A1 (en) * 2020-01-23 2021-07-28 Paean Aesthetics Inc Micro-spicule composition to control its shape and method for producing the same
JP2021143146A (ja) * 2020-03-11 2021-09-24 コスメディ製薬株式会社 天然保湿因子含有貼付型化粧料
EP4134121A4 (en) * 2020-04-06 2024-05-08 Illon Co., Ltd. COSMETIC PRODUCT INJECTOR ON WHICH MICRO-NEEDLES ARE MOUNTED TO INDUCE THE ABSORPTION OF COSMETIC PRODUCTS, AND METHOD FOR MANUFACTURING SAME
CN112675124A (zh) * 2020-12-29 2021-04-20 浙江摩达生物科技有限公司 一种改性自溶性透明质酸微针的制备方法及其在戒毒药物领域的应用
CN113520905A (zh) * 2021-03-25 2021-10-22 甘肃天际生物科技有限公司 一种速溶胶原蛋白微针及其制备方法
KR102683399B1 (ko) * 2021-12-14 2024-07-10 주식회사 라파스 마이크로니들 패치 및 마이크로니들 패치의 제조방법
WO2023197672A1 (zh) * 2022-04-15 2023-10-19 优微（珠海）生物科技有限公司 一种平面微针、微针贴及制造设备、立形设备和制备方法
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004105729A2 (en) * 2002-08-08 2004-12-09 Alza Corporation Transdermal vaccine delivery device having coated microprotrusions
WO2005004729A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
WO2006080508A1 (ja) * 2005-01-31 2006-08-03 Bioserentach Co., Ltd. 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4090018B2 (ja) 2002-02-18 2008-05-28 Ｆｏｒ Ｈｅａｄ株式会社 機能性マイクロパイル及びその製造方法
WO2004108203A1 (ja) 2003-06-10 2004-12-16 Medrx Co., Ltd. 経皮投薬用パッドベース、及び注射針
CN2662899Y (zh) * 2003-11-20 2004-12-15 陈以国 梅花丛针贴
WO2006067587A2 (en) * 2004-12-22 2006-06-29 Pfizer Limited Nonnucleoside inhibitors of hiv-1 reverse transcriptase
CN102408470A (zh) * 2005-12-23 2012-04-11 洛桑大学 用作神经递质分泌抑制剂和肌肉松弛诱导物的合成肽

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004105729A2 (en) * 2002-08-08 2004-12-09 Alza Corporation Transdermal vaccine delivery device having coated microprotrusions
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
WO2005004729A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
WO2006080508A1 (ja) * 2005-01-31 2006-08-03 Bioserentach Co., Ltd. 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2011002034A1 (ja) * 2009-07-01 2012-12-13 凸版印刷株式会社 針状体
JP2014223554A (ja) * 2009-07-01 2014-12-04 凸版印刷株式会社 針状体
JP5663477B2 (ja) * 2009-07-01 2015-02-04 凸版印刷株式会社 針状体
WO2011002034A1 (ja) * 2009-07-01 2011-01-06 凸版印刷株式会社 針状体
US10603477B2 (en) 2014-03-28 2020-03-31 Allergan, Inc. Dissolvable microneedles for skin treatment
US10987503B2 (en) 2014-03-28 2021-04-27 Allergan, Inc. Dissolvable microneedles for skin treatment
CN109069812A (zh) * 2016-04-07 2018-12-21 实验室和人们 利用生物可吸收金属的微针
CN109069812B (zh) * 2016-04-07 2021-05-07 实验室和人们 利用生物可吸收金属的微针
US11065428B2 (en) 2017-02-17 2021-07-20 Allergan, Inc. Microneedle array with active ingredient
WO2020004666A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020004428A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020017441A1 (en) 2018-07-17 2020-01-23 L'oreal Microneedle sheet
WO2020130157A1 (en) 2018-12-21 2020-06-25 L'oreal Kit and cosmetic process using microneedle sheet
EP3695876A1 (en) 2019-02-18 2020-08-19 L'oreal Pencil for inserting micro-implants inside upper skin layers
WO2020169443A1 (en) 2019-02-18 2020-08-27 L'oreal Pencil for inserting micro-implants inside upper skin layers
EP3698841A1 (en) 2019-02-19 2020-08-26 L'oreal Injection device
WO2020169640A1 (en) 2019-02-19 2020-08-27 L'oreal Injection device
WO2020200407A1 (en) 2019-03-29 2020-10-08 L'oreal Frozen micro-implants and method of making same

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US20100228203A1 (en) 2010-09-09
KR20100025509A (ko) 2010-03-09
KR101400545B1 (ko) 2014-05-28
JP2008284318A (ja) 2008-11-27

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